Drosophila melanogaster

34 known processes

Fancl (Dmel_CG12812)

CG12812 gene product from transcript CG12812-RA

(Aliases: FANCL,Dmel\CG12812,CG12812)

Fancl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle phase transition GO:1901987 130 0.247
cell cycle phase transition GO:0044770 140 0.237
regulation of mitotic cell cycle phase transition GO:1901990 130 0.200
negative regulation of cell cycle phase transition GO:1901988 103 0.188
nuclear division GO:0000280 332 0.187
negative regulation of cell cycle GO:0045786 116 0.170
negative regulation of mitotic cell cycle GO:0045930 109 0.164
regulation of cell cycle GO:0051726 291 0.142
cell cycle checkpoint GO:0000075 95 0.135
regulation of cell cycle process GO:0010564 181 0.122
mitotic cell cycle checkpoint GO:0007093 88 0.117
catabolic process GO:0009056 409 0.111
dna integrity checkpoint GO:0031570 81 0.099
mitotic dna damage checkpoint GO:0044773 74 0.094
negative regulation of cell cycle process GO:0010948 109 0.089
cellular catabolic process GO:0044248 372 0.081
response to other organism GO:0051707 293 0.079
imaginal disc derived appendage morphogenesis GO:0035114 395 0.077
mitotic cell cycle phase transition GO:0044772 138 0.076
cellular response to dna damage stimulus GO:0006974 223 0.073
dna repair GO:0006281 54 0.064
organelle fission GO:0048285 340 0.063
wing disc morphogenesis GO:0007472 344 0.061
organonitrogen compound metabolic process GO:1901564 318 0.057
organic substance catabolic process GO:1901575 308 0.057
single organism catabolic process GO:0044712 228 0.054
dna damage checkpoint GO:0000077 78 0.053
mitotic nuclear division GO:0007067 213 0.051
establishment of localization in cell GO:0051649 402 0.050
response to biotic stimulus GO:0009607 294 0.046
mitotic dna integrity checkpoint GO:0044774 75 0.045
small molecule metabolic process GO:0044281 305 0.044
nucleotide metabolic process GO:0009117 161 0.043
reproductive behavior GO:0019098 122 0.036
endocytosis GO:0006897 310 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.035
response to external biotic stimulus GO:0043207 293 0.035
defense response to bacterium GO:0042742 178 0.034
organelle assembly GO:0070925 198 0.034
response to organophosphorus GO:0046683 2 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
vesicle mediated transport GO:0016192 381 0.032
response to bacterium GO:0009617 198 0.031
regulation of localization GO:0032879 275 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.031
guanosine containing compound catabolic process GO:1901069 74 0.030
intracellular transport GO:0046907 228 0.030
organic substance transport GO:0071702 257 0.030
response to abiotic stimulus GO:0009628 341 0.030
multi organism behavior GO:0051705 175 0.030
oxoacid metabolic process GO:0043436 103 0.030
carboxylic acid metabolic process GO:0019752 92 0.029
determination of adult lifespan GO:0008340 137 0.029
regulation of mitotic cell cycle GO:0007346 190 0.028
cell death GO:0008219 279 0.028
cell division GO:0051301 248 0.028
appendage morphogenesis GO:0035107 397 0.028
response to light stimulus GO:0009416 124 0.027
neurological system process GO:0050877 358 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
heterocycle catabolic process GO:0046700 166 0.026
regulation of molecular function GO:0065009 217 0.026
single organism intracellular transport GO:1902582 207 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
immune response GO:0006955 246 0.025
appendage development GO:0048736 401 0.025
organic acid metabolic process GO:0006082 103 0.025
aging GO:0007568 143 0.024
aromatic compound catabolic process GO:0019439 166 0.024
cellular protein modification process GO:0006464 438 0.024
homeostatic process GO:0042592 199 0.023
proteolysis GO:0006508 192 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
sister chromatid segregation GO:0000819 92 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.022
response to monosaccharide GO:0034284 4 0.021
ion transport GO:0006811 145 0.021
organophosphate metabolic process GO:0019637 195 0.021
response to lipopolysaccharide GO:0032496 4 0.021
defense response to other organism GO:0098542 225 0.021
cellular amide metabolic process GO:0043603 80 0.021
mitotic sister chromatid segregation GO:0000070 87 0.021
regulation of growth GO:0040008 233 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
regulation of catalytic activity GO:0050790 185 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
response to nutrient levels GO:0031667 114 0.020
spermatogenesis GO:0007283 200 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
regulation of mitosis GO:0007088 56 0.019
phagocytosis GO:0006909 215 0.019
defense response GO:0006952 300 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
positive regulation of signal transduction GO:0009967 223 0.018
death GO:0016265 284 0.018
programmed cell death GO:0012501 257 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
locomotory behavior GO:0007626 176 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
steroid catabolic process GO:0006706 1 0.018
fat soluble vitamin biosynthetic process GO:0042362 1 0.018
multicellular organismal aging GO:0010259 140 0.018
humoral immune response GO:0006959 117 0.018
regionalization GO:0003002 416 0.018
chromosome organization GO:0051276 360 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
protein dna complex subunit organization GO:0071824 86 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
protein transport GO:0015031 155 0.017
regulation of cell death GO:0010941 173 0.017
tissue migration GO:0090130 155 0.017
regulation of cellular localization GO:0060341 136 0.017
ovarian follicle cell development GO:0030707 248 0.017
regulation of response to stress GO:0080134 200 0.017
regulation of organelle organization GO:0033043 196 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
lateral inhibition GO:0046331 206 0.017
growth GO:0040007 359 0.016
compound eye development GO:0048749 307 0.016
regulation of proteolysis GO:0030162 87 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
secretion GO:0046903 109 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
regulation of transport GO:0051049 181 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
cellular ketone metabolic process GO:0042180 24 0.016
negative regulation of signal transduction GO:0009968 206 0.016
male gamete generation GO:0048232 201 0.016
regulation of cellular catabolic process GO:0031329 157 0.015
cytoplasmic transport GO:0016482 130 0.015
central nervous system development GO:0007417 201 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
purine containing compound metabolic process GO:0072521 155 0.015
fat soluble vitamin metabolic process GO:0006775 1 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
intracellular signal transduction GO:0035556 300 0.015
sterol homeostasis GO:0055092 4 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
nucleoside metabolic process GO:0009116 127 0.015
gland development GO:0048732 191 0.015
regulation of developmental growth GO:0048638 174 0.015
cell fate determination GO:0001709 91 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
rna processing GO:0006396 147 0.015
chromosome segregation GO:0007059 157 0.015
dna metabolic process GO:0006259 227 0.015
positive regulation of signaling GO:0023056 243 0.014
single organism biosynthetic process GO:0044711 206 0.014
cellular macromolecule localization GO:0070727 220 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
phosphorylation GO:0016310 294 0.014
negative regulation of gene expression GO:0010629 387 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
regulation of protein metabolic process GO:0051246 256 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
sensory organ morphogenesis GO:0090596 260 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
protein processing GO:0016485 68 0.014
autophagic cell death GO:0048102 83 0.014
adult behavior GO:0030534 137 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
nucleotide catabolic process GO:0009166 109 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
gtp catabolic process GO:0006184 72 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
positive regulation of transport GO:0051050 92 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
developmental growth GO:0048589 280 0.013
lipid metabolic process GO:0006629 121 0.013
synaptic transmission GO:0007268 288 0.013
trna modification GO:0006400 2 0.013
respiratory system development GO:0060541 213 0.013
innate immune response GO:0045087 144 0.013
camera type eye development GO:0043010 4 0.013
localization of cell GO:0051674 257 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
positive regulation of gene expression GO:0010628 290 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
nucleoside catabolic process GO:0009164 112 0.013
establishment of organelle localization GO:0051656 122 0.013
imaginal disc derived appendage development GO:0048737 399 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
dna replication GO:0006260 48 0.012
cellular amine metabolic process GO:0044106 12 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
cell growth GO:0016049 108 0.012
protein localization GO:0008104 284 0.012
macromolecule catabolic process GO:0009057 161 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
epithelium migration GO:0090132 148 0.012
meiotic cell cycle process GO:1903046 132 0.012
regulation of hydrolase activity GO:0051336 97 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
epithelial cell development GO:0002064 274 0.012
nitrogen compound transport GO:0071705 85 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
secretion by cell GO:0032940 101 0.012
lauric acid metabolic process GO:0048252 1 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
antimicrobial humoral response GO:0019730 99 0.012
mitotic g2 m transition checkpoint GO:0044818 70 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
protein complex biogenesis GO:0070271 201 0.012
cell motility GO:0048870 251 0.012
apoptotic process GO:0006915 159 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
response to extracellular stimulus GO:0009991 116 0.012
regulation of nuclear division GO:0051783 58 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
response to hexose GO:0009746 3 0.012
regulation of catabolic process GO:0009894 170 0.012
response to organic substance GO:0010033 284 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
cellularization GO:0007349 90 0.011
response to glucose GO:0009749 2 0.011
aggressive behavior GO:0002118 63 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
body morphogenesis GO:0010171 2 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
polyol biosynthetic process GO:0046173 3 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
regulation of anatomical structure size GO:0090066 163 0.011
regulation of protein localization GO:0032880 76 0.011
organophosphate catabolic process GO:0046434 112 0.011
protein phosphorylation GO:0006468 169 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
l amino acid import GO:0043092 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
protein complex assembly GO:0006461 200 0.011
ovarian follicle cell migration GO:0007297 121 0.011
cell migration GO:0016477 238 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
toxin metabolic process GO:0009404 2 0.011
response to starvation GO:0042594 97 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
intracellular protein transport GO:0006886 104 0.011
compound eye morphogenesis GO:0001745 249 0.011
cell proliferation GO:0008283 299 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
spindle organization GO:0007051 253 0.011
negative regulation of cell communication GO:0010648 223 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
establishment of protein localization GO:0045184 163 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
axonogenesis GO:0007409 290 0.010
dendrite morphogenesis GO:0048813 199 0.010
regulation of programmed cell death GO:0043067 152 0.010
hindbrain development GO:0030902 2 0.010
regulation of cell differentiation GO:0045595 302 0.010
chemical homeostasis GO:0048878 92 0.010
macromolecular complex assembly GO:0065003 256 0.010
tissue death GO:0016271 102 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
forebrain development GO:0030900 2 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
cholesterol homeostasis GO:0042632 3 0.010
single organism behavior GO:0044708 391 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
production of molecular mediator of immune response GO:0002440 46 0.010
kidney development GO:0001822 3 0.010
gtp metabolic process GO:0046039 72 0.010
amine metabolic process GO:0009308 12 0.010

Fancl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.018
nervous system disease DOID:863 0 0.015
cardiovascular system disease DOID:1287 0 0.013
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013