Drosophila melanogaster

123 known processes

pont (Dmel_CG4003)

pontin

(Aliases: Dmel\CG4003,0229/05,dpon,Pont,Pontin,pon,Tip49/Pontin,Tip49,l(3)S022905,dPon,dPontin,anon-WO0118547.698,CG4003)

pont biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cullin deneddylation GO:0010388 3 0.677
regulation of meiosis GO:0040020 3 0.580
embryo development ending in birth or egg hatching GO:0009792 152 0.489
meiotic cell cycle GO:0051321 171 0.435
nuclear division GO:0000280 332 0.302
regulation of mitotic cell cycle GO:0007346 190 0.286
regulation of cell cycle process GO:0010564 181 0.274
meiotic nuclear division GO:0007126 151 0.268
cell proliferation GO:0008283 299 0.263
regulation of cell division GO:0051302 72 0.239
chromatin modification GO:0016568 147 0.231
organelle fission GO:0048285 340 0.220
mrna metabolic process GO:0016071 124 0.218
cell cycle phase transition GO:0044770 140 0.217
regulation of cell cycle GO:0051726 291 0.210
negative regulation of gene expression GO:0010629 387 0.192
cell division GO:0051301 248 0.189
endocytosis GO:0006897 310 0.189
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.188
regulation of nuclear division GO:0051783 58 0.186
immune system process GO:0002376 347 0.186
establishment of localization in cell GO:0051649 402 0.176
regulation of cellular protein metabolic process GO:0032268 243 0.171
regulation of cell cycle phase transition GO:1901987 130 0.159
cellular macromolecule localization GO:0070727 220 0.158
negative regulation of cellular metabolic process GO:0031324 382 0.156
establishment of organelle localization GO:0051656 122 0.149
cellular protein modification process GO:0006464 438 0.146
single organism cellular localization GO:1902580 180 0.143
negative regulation of cell cycle phase transition GO:1901988 103 0.140
regulation of mitotic cell cycle phase transition GO:1901990 130 0.139
macromolecule catabolic process GO:0009057 161 0.130
mitotic cell cycle checkpoint GO:0007093 88 0.129
organic substance catabolic process GO:1901575 308 0.126
cellular catabolic process GO:0044248 372 0.126
cellular macromolecule catabolic process GO:0044265 136 0.125
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.123
regulation of phosphorus metabolic process GO:0051174 210 0.116
protein import into nucleus GO:0006606 51 0.114
protein modification process GO:0036211 438 0.114
catabolic process GO:0009056 409 0.108
regulation of organelle organization GO:0033043 196 0.106
sex differentiation GO:0007548 81 0.104
cell death GO:0008219 279 0.103
regulation of phosphate metabolic process GO:0019220 210 0.102
regulation of meiotic cell cycle GO:0051445 9 0.101
negative regulation of catabolic process GO:0009895 36 0.098
spindle organization GO:0007051 253 0.097
vesicle mediated transport GO:0016192 381 0.095
mitotic dna integrity checkpoint GO:0044774 75 0.093
mitotic nuclear division GO:0007067 213 0.092
intracellular protein transport GO:0006886 104 0.086
regulation of protein metabolic process GO:0051246 256 0.086
embryonic pattern specification GO:0009880 174 0.082
regulation of cellular catabolic process GO:0031329 157 0.082
regulation of catabolic process GO:0009894 170 0.078
imaginal disc derived appendage morphogenesis GO:0035114 395 0.076
negative regulation of mitotic cell cycle GO:0045930 109 0.072
imaginal disc derived appendage development GO:0048737 399 0.069
post embryonic appendage morphogenesis GO:0035120 385 0.068
small molecule metabolic process GO:0044281 305 0.067
organic cyclic compound catabolic process GO:1901361 168 0.066
protein targeting to nucleus GO:0044744 51 0.064
organelle localization GO:0051640 148 0.063
negative regulation of biosynthetic process GO:0009890 277 0.062
ribonucleoprotein complex assembly GO:0022618 23 0.062
rrna processing GO:0006364 3 0.061
negative regulation of cellular biosynthetic process GO:0031327 277 0.061
protein import GO:0017038 55 0.061
cellular nitrogen compound catabolic process GO:0044270 165 0.060
establishment of protein localization GO:0045184 163 0.060
ribonucleoprotein complex subunit organization GO:0071826 28 0.060
modification dependent macromolecule catabolic process GO:0043632 79 0.059
positive regulation of gene expression GO:0010628 290 0.059
organonitrogen compound metabolic process GO:1901564 318 0.058
protein modification by small protein conjugation or removal GO:0070647 106 0.058
positive regulation of phosphate metabolic process GO:0045937 139 0.058
protein localization GO:0008104 284 0.055
growth GO:0040007 359 0.055
regulation of proteasomal protein catabolic process GO:0061136 39 0.055
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.052
establishment of protein localization to organelle GO:0072594 62 0.052
carbohydrate derivative metabolic process GO:1901135 217 0.052
negative regulation of cell cycle process GO:0010948 109 0.051
development of primary sexual characteristics GO:0045137 50 0.050
organelle assembly GO:0070925 198 0.049
intracellular transport GO:0046907 228 0.049
immune response GO:0006955 246 0.049
positive regulation of catabolic process GO:0009896 105 0.048
posttranscriptional regulation of gene expression GO:0010608 145 0.047
reproductive system development GO:0061458 74 0.045
protein transport GO:0015031 155 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.044
single organism catabolic process GO:0044712 228 0.044
pole plasm rna localization GO:0007316 52 0.044
cellular protein catabolic process GO:0044257 83 0.043
phagocytosis GO:0006909 215 0.043
mitotic spindle organization GO:0007052 220 0.043
larval development GO:0002164 104 0.043
protein complex biogenesis GO:0070271 201 0.043
regulation of response to stress GO:0080134 200 0.043
cell migration GO:0016477 238 0.043
gland development GO:0048732 191 0.043
regulation of catalytic activity GO:0050790 185 0.042
mrna processing GO:0006397 104 0.042
imaginal disc derived wing morphogenesis GO:0007476 337 0.042
dna damage checkpoint GO:0000077 78 0.041
atp metabolic process GO:0046034 49 0.041
positive regulation of cellular catabolic process GO:0031331 95 0.041
reproductive structure development GO:0048608 74 0.041
gene silencing GO:0016458 138 0.041
programmed cell death GO:0012501 257 0.041
negative regulation of cell cycle GO:0045786 116 0.040
negative regulation of nucleic acid templated transcription GO:1903507 240 0.040
rna interference GO:0016246 27 0.039
heterocycle catabolic process GO:0046700 166 0.039
posttranscriptional gene silencing by rna GO:0035194 45 0.039
nuclear transport GO:0051169 72 0.038
regulation of apoptotic process GO:0042981 130 0.038
protein deneddylation GO:0000338 8 0.037
regulation of immune system process GO:0002682 176 0.037
covalent chromatin modification GO:0016569 106 0.037
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
negative regulation of cellular protein metabolic process GO:0032269 85 0.036
cytoplasmic transport GO:0016482 130 0.036
response to external biotic stimulus GO:0043207 293 0.035
regulation of ras protein signal transduction GO:0046578 93 0.035
regulation of phosphorylation GO:0042325 147 0.034
mitotic cell cycle phase transition GO:0044772 138 0.034
defense response GO:0006952 300 0.034
positive regulation of catalytic activity GO:0043085 118 0.033
protein catabolic process GO:0030163 101 0.033
defense response to other organism GO:0098542 225 0.033
germarium derived egg chamber formation GO:0007293 101 0.033
oocyte differentiation GO:0009994 145 0.033
dna integrity checkpoint GO:0031570 81 0.033
maternal determination of anterior posterior axis embryo GO:0008358 74 0.033
positive regulation of cellular amine metabolic process GO:0033240 0 0.032
rna processing GO:0006396 147 0.032
response to biotic stimulus GO:0009607 294 0.032
oocyte anterior posterior axis specification GO:0007314 72 0.031
response to dsrna GO:0043331 15 0.031
positive regulation of growth GO:0045927 75 0.031
nucleotide catabolic process GO:0009166 109 0.031
pole plasm mrna localization GO:0019094 49 0.031
proteolysis GO:0006508 192 0.031
ubiquitin dependent protein catabolic process GO:0006511 78 0.031
regulation of immune response GO:0050776 118 0.031
regulation of intracellular signal transduction GO:1902531 236 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.030
regulation of developmental growth GO:0048638 174 0.030
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
segmentation GO:0035282 207 0.029
regulation of defense response GO:0031347 102 0.028
rna catabolic process GO:0006401 37 0.028
ribonucleoprotein complex biogenesis GO:0022613 31 0.028
positive regulation of response to stimulus GO:0048584 323 0.028
localization of cell GO:0051674 257 0.028
nucleoside monophosphate catabolic process GO:0009125 39 0.028
camera type eye development GO:0043010 4 0.028
apoptotic process GO:0006915 159 0.028
regulation of innate immune response GO:0045088 71 0.027
single organism nuclear import GO:1902593 51 0.027
compound eye development GO:0048749 307 0.027
organic substance transport GO:0071702 257 0.027
intracellular signal transduction GO:0035556 300 0.027
gene silencing by rna GO:0031047 57 0.027
intracellular mrna localization GO:0008298 66 0.027
positive regulation of biosynthetic process GO:0009891 316 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
negative regulation of response to stimulus GO:0048585 258 0.026
ras protein signal transduction GO:0007265 88 0.026
macromolecule methylation GO:0043414 45 0.026
cell cycle checkpoint GO:0000075 95 0.026
oocyte axis specification GO:0007309 108 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
regulation of molecular function GO:0065009 217 0.026
pole plasm oskar mrna localization GO:0045451 46 0.026
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.026
posttranscriptional gene silencing GO:0016441 46 0.026
small gtpase mediated signal transduction GO:0007264 88 0.026
regulation of protein modification process GO:0031399 112 0.025
regulation of cellular protein catabolic process GO:1903362 44 0.025
oocyte development GO:0048599 124 0.025
nuclear import GO:0051170 51 0.025
eye development GO:0001654 323 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
response to other organism GO:0051707 293 0.025
positive regulation of nucleic acid templated transcription GO:1903508 266 0.024
nucleocytoplasmic transport GO:0006913 72 0.024
regulation of mitotic sister chromatid segregation GO:0033047 28 0.024
chromosome organization GO:0051276 360 0.024
regulation of localization GO:0032879 275 0.024
blastoderm segmentation GO:0007350 159 0.024
purine containing compound metabolic process GO:0072521 155 0.024
aromatic compound catabolic process GO:0019439 166 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.023
fertilization GO:0009566 26 0.023
smad protein import into nucleus GO:0007184 11 0.023
histone modification GO:0016570 106 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
purine nucleotide catabolic process GO:0006195 109 0.023
cell motility GO:0048870 251 0.023
macromolecular complex assembly GO:0065003 256 0.022
protein localization to nucleus GO:0034504 55 0.022
cellular protein localization GO:0034613 160 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.021
multicellular organismal reproductive behavior GO:0033057 110 0.021
regulation of small gtpase mediated signal transduction GO:0051056 93 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
cytoplasm organization GO:0007028 64 0.021
mitotic g2 dna damage checkpoint GO:0007095 69 0.021
genitalia development GO:0048806 26 0.020
protein localization to organelle GO:0033365 82 0.020
regulation of intracellular protein transport GO:0033157 46 0.020
mrna cis splicing via spliceosome GO:0045292 1 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
mitotic g2 m transition checkpoint GO:0044818 70 0.020
regulation of proteolysis GO:0030162 87 0.020
regulation of mrna 3 end processing GO:0031440 7 0.020
regulation of erk1 and erk2 cascade GO:0070372 39 0.020
sensory organ morphogenesis GO:0090596 260 0.020
embryonic morphogenesis GO:0048598 206 0.020
protein acylation GO:0043543 42 0.020
positive regulation of transcription dna templated GO:0045893 266 0.019
death GO:0016265 284 0.019
peptidyl amino acid modification GO:0018193 105 0.019
chromatin organization GO:0006325 207 0.019
oxoacid metabolic process GO:0043436 103 0.019
regulation of programmed cell death GO:0043067 152 0.019
homeostatic process GO:0042592 199 0.019
retina development in camera type eye GO:0060041 4 0.018
mitotic cytokinesis GO:0000281 50 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
molting cycle GO:0042303 56 0.018
regulation of cell proliferation GO:0042127 163 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
regionalization GO:0003002 416 0.018
positive regulation of molecular function GO:0044093 136 0.018
protein complex assembly GO:0006461 200 0.017
purine nucleoside monophosphate catabolic process GO:0009128 38 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
receptor mediated endocytosis GO:0006898 21 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
positive regulation of ras protein signal transduction GO:0046579 43 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
histone methylation GO:0016571 40 0.016
protein alkylation GO:0008213 43 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
spliceosomal complex assembly GO:0000245 1 0.016
exocrine system development GO:0035272 162 0.016
response to organic substance GO:0010033 284 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
rna localization GO:0006403 115 0.015
regulation of autophagy GO:0010506 62 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
purine containing compound catabolic process GO:0072523 112 0.015
nucleus organization GO:0006997 45 0.015
organelle inheritance GO:0048308 2 0.015
cellular homeostasis GO:0019725 80 0.015
ribosomal large subunit biogenesis GO:0042273 1 0.015
protein maturation GO:0051604 71 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
erk1 and erk2 cascade GO:0070371 39 0.014
regulation of cell death GO:0010941 173 0.014
smoothened signaling pathway GO:0007224 49 0.014
salivary gland development GO:0007431 162 0.014
regulation of mapk cascade GO:0043408 92 0.014
single organism intracellular transport GO:1902582 207 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
embryonic axis specification GO:0000578 107 0.014
positive regulation of immune response GO:0050778 63 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
regulation of protein localization GO:0032880 76 0.014
methylation GO:0032259 47 0.014
body morphogenesis GO:0010171 2 0.013
mitochondrion organization GO:0007005 65 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
negative regulation of rna splicing GO:0033119 5 0.013
cellular response to nutrient GO:0031670 1 0.013
protein neddylation GO:0045116 5 0.013
regulation of reproductive process GO:2000241 54 0.013
defense response to bacterium GO:0042742 178 0.013
multi organism reproductive behavior GO:0044705 121 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
eye morphogenesis GO:0048592 260 0.012
nuclear rna surveillance GO:0071027 3 0.012
compound eye morphogenesis GO:0001745 249 0.012
organophosphate catabolic process GO:0046434 112 0.012
oocyte construction GO:0007308 112 0.012
nucleoside catabolic process GO:0009164 112 0.012
appendage morphogenesis GO:0035107 397 0.012
response to organic cyclic compound GO:0014070 89 0.012
ribonucleoside monophosphate catabolic process GO:0009158 39 0.012
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
cytokinesis GO:0000910 90 0.012
negative regulation of chromosome organization GO:2001251 19 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
wing disc pattern formation GO:0035222 66 0.012
cellular component disassembly GO:0022411 46 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
response to oxygen containing compound GO:1901700 200 0.012
phosphorylation GO:0016310 294 0.012
positive regulation of cell communication GO:0010647 250 0.012
regulation of chromosome segregation GO:0051983 32 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
negative regulation of sister chromatid segregation GO:0033046 13 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
histone acetylation GO:0016573 38 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
formation of a compartment boundary GO:0060288 4 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
positive regulation of cell death GO:0010942 69 0.011
gonad development GO:0008406 50 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
regulation of protein catabolic process GO:0042176 55 0.011
chromosome separation GO:0051304 42 0.011
developmental maturation GO:0021700 172 0.011
response to sterol GO:0036314 34 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
regulation of cell differentiation GO:0045595 302 0.010
modification dependent protein catabolic process GO:0019941 78 0.010
muscle structure development GO:0061061 224 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.010
pole plasm assembly GO:0007315 61 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
single organism biosynthetic process GO:0044711 206 0.010
ribonucleotide metabolic process GO:0009259 145 0.010

pont disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010