Drosophila melanogaster

17 known processes

PH4alphaSG2 (Dmel_CG1546)

prolyl-4-hydroxylase-alpha SG2

(Aliases: CG1546,Dmel\CG1546,SG2)

PH4alphaSG2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.042
small molecule metabolic process GO:0044281 305 0.042
appendage development GO:0048736 401 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
wing disc morphogenesis GO:0007472 344 0.040
response to abiotic stimulus GO:0009628 341 0.040
imaginal disc derived appendage development GO:0048737 399 0.039
post embryonic appendage morphogenesis GO:0035120 385 0.039
single organism behavior GO:0044708 391 0.038
appendage morphogenesis GO:0035107 397 0.036
catabolic process GO:0009056 409 0.036
protein modification process GO:0036211 438 0.035
Rat
immune system process GO:0002376 347 0.035
regionalization GO:0003002 416 0.033
response to external biotic stimulus GO:0043207 293 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
humoral immune response GO:0006959 117 0.033
body morphogenesis GO:0010171 2 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
Fly
response to organic substance GO:0010033 284 0.030
immune response GO:0006955 246 0.030
cellular protein modification process GO:0006464 438 0.029
Rat
vesicle mediated transport GO:0016192 381 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
compound eye development GO:0048749 307 0.028
lateral inhibition GO:0046331 206 0.028
Fly
regulation of multicellular organismal development GO:2000026 414 0.028
organic substance catabolic process GO:1901575 308 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
negative regulation of gene expression GO:0010629 387 0.028
organic substance transport GO:0071702 257 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
response to lipopolysaccharide GO:0032496 4 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
endocytosis GO:0006897 310 0.027
epithelial cell differentiation GO:0030855 322 0.027
neurological system process GO:0050877 358 0.026
cellular catabolic process GO:0044248 372 0.026
response to organophosphorus GO:0046683 2 0.026
anion homeostasis GO:0055081 3 0.026
organic acid metabolic process GO:0006082 103 0.025
oxoacid metabolic process GO:0043436 103 0.025
ethanolamine containing compound metabolic process GO:0042439 4 0.025
cellular amine metabolic process GO:0044106 12 0.025
phagocytosis GO:0006909 215 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
amine metabolic process GO:0009308 12 0.024
response to other organism GO:0051707 293 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
positive regulation of cell communication GO:0010647 250 0.024
developmental growth GO:0048589 280 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
response to biotic stimulus GO:0009607 294 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
taxis GO:0042330 304 0.023
compound eye morphogenesis GO:0001745 249 0.023
organelle fission GO:0048285 340 0.023
eye development GO:0001654 323 0.023
salivary gland development GO:0007431 162 0.022
single organism biosynthetic process GO:0044711 206 0.022
response to oxygen containing compound GO:1901700 200 0.022
intracellular signal transduction GO:0035556 300 0.022
adult behavior GO:0030534 137 0.022
forebrain development GO:0030900 2 0.022
exocrine system development GO:0035272 162 0.022
epithelial cell development GO:0002064 274 0.022
single organism catabolic process GO:0044712 228 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
regulation of localization GO:0032879 275 0.021
death GO:0016265 284 0.021
organophosphate metabolic process GO:0019637 195 0.021
peptidyl proline modification GO:0018208 3 0.021
Rat
phosphorylation GO:0016310 294 0.021
gland development GO:0048732 191 0.021
mating GO:0007618 120 0.021
positive regulation of signaling GO:0023056 243 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
kidney development GO:0001822 3 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.020
growth GO:0040007 359 0.020
establishment of localization in cell GO:0051649 402 0.020
camera type eye development GO:0043010 4 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
innate immune response GO:0045087 144 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
positive regulation of cell migration GO:0030335 2 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
eye morphogenesis GO:0048592 260 0.019
positive regulation of gene expression GO:0010628 290 0.019
chemotaxis GO:0006935 249 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
cell death GO:0008219 279 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
response to monosaccharide GO:0034284 4 0.019
protein localization GO:0008104 284 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
protein hydroxylation GO:0018126 1 0.019
Rat
regulation of cellular amine metabolic process GO:0033238 3 0.019
axon development GO:0061564 297 0.018
sensory organ morphogenesis GO:0090596 260 0.018
ovarian follicle cell development GO:0030707 248 0.018
negative regulation of signal transduction GO:0009968 206 0.018
regulation of cell differentiation GO:0045595 302 0.018
positive regulation of signal transduction GO:0009967 223 0.018
axon guidance GO:0007411 233 0.018
hormone catabolic process GO:0042447 3 0.018
telencephalon development GO:0021537 2 0.018
axonogenesis GO:0007409 290 0.018
neuron projection guidance GO:0097485 241 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
regulation of protein metabolic process GO:0051246 256 0.018
regulation of multi organism process GO:0043900 131 0.018
cell proliferation GO:0008283 299 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
nuclear division GO:0000280 332 0.018
regulation of developmental growth GO:0048638 174 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
cellular ketone metabolic process GO:0042180 24 0.017
tube development GO:0035295 244 0.017
response to nutrient levels GO:0031667 114 0.017
response to bacterium GO:0009617 198 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
localization of cell GO:0051674 257 0.017
acylglycerol biosynthetic process GO:0046463 2 0.017
neutral lipid biosynthetic process GO:0046460 2 0.017
actin filament based process GO:0030029 220 0.017
steroid catabolic process GO:0006706 1 0.017
proteolysis GO:0006508 192 0.017
response to wounding GO:0009611 94 0.017
response to temperature stimulus GO:0009266 106 0.017
response to radiation GO:0009314 155 0.017
regulation of molecular function GO:0065009 217 0.017
cellular response to ethanol GO:0071361 4 0.016
negative regulation of developmental process GO:0051093 201 0.016
negative regulation of cell communication GO:0010648 223 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
cell motility GO:0048870 251 0.016
programmed cell death GO:0012501 257 0.016
fat soluble vitamin biosynthetic process GO:0042362 1 0.016
nucleotide metabolic process GO:0009117 161 0.016
negative regulation of signaling GO:0023057 219 0.016
cellular macromolecule localization GO:0070727 220 0.016
gland morphogenesis GO:0022612 145 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
cell migration GO:0016477 238 0.016
regulation of nervous system development GO:0051960 248 0.016
immune response activating signal transduction GO:0002757 2 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
regulation of catalytic activity GO:0050790 185 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
regulation of cell cycle GO:0051726 291 0.016
peptidyl proline hydroxylation GO:0019511 1 0.016
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
establishment of tissue polarity GO:0007164 87 0.016
regulation of anatomical structure size GO:0090066 163 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
regulation of transport GO:0051049 181 0.015
response to hexose GO:0009746 3 0.015
segmentation GO:0035282 207 0.015
digestive system development GO:0055123 149 0.015
defense response to other organism GO:0098542 225 0.015
salivary gland morphogenesis GO:0007435 145 0.015
neurotransmitter metabolic process GO:0042133 2 0.015
lipid metabolic process GO:0006629 121 0.015
intracellular transport GO:0046907 228 0.015
response to glucose GO:0009749 2 0.015
xenobiotic catabolic process GO:0042178 1 0.015
connective tissue development GO:0061448 3 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of immune system process GO:0002682 176 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
androgen metabolic process GO:0008209 1 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
positive regulation of cell motility GO:2000147 3 0.015
ion transport GO:0006811 145 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
antimicrobial humoral response GO:0019730 99 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
chromosome segregation GO:0007059 157 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
tissue morphogenesis GO:0048729 297 0.015
regulation of cell development GO:0060284 215 0.015
tube morphogenesis GO:0035239 191 0.015
response to extracellular stimulus GO:0009991 116 0.015
transmembrane transport GO:0055085 139 0.015
wnt signaling pathway GO:0016055 98 0.015
spermatogenesis GO:0007283 200 0.014
developmental maturation GO:0021700 172 0.014
male gamete generation GO:0048232 201 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
sterol homeostasis GO:0055092 4 0.014
homeostatic process GO:0042592 199 0.014
regulation of response to stress GO:0080134 200 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
multi organism behavior GO:0051705 175 0.014
ameboidal type cell migration GO:0001667 151 0.014
cuticle development GO:0042335 86 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
hindbrain development GO:0030902 2 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
open tracheal system development GO:0007424 204 0.014
neuron recognition GO:0008038 101 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
acetylcholine metabolic process GO:0008291 2 0.014
organic hydroxy compound metabolic process GO:1901615 83 0.014
acylglycerol catabolic process GO:0046464 3 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
l glutamate import GO:0051938 1 0.014
single organism intracellular transport GO:1902582 207 0.014
aromatic compound catabolic process GO:0019439 166 0.014
digestive tract development GO:0048565 149 0.014
purine containing compound metabolic process GO:0072521 155 0.014
macromolecular complex assembly GO:0065003 256 0.014
regulation of growth GO:0040008 233 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
developmental programmed cell death GO:0010623 138 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
gene silencing GO:0016458 138 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
wound healing GO:0042060 75 0.013
limb development GO:0060173 1 0.013
protein transport GO:0015031 155 0.013
heterocycle catabolic process GO:0046700 166 0.013
spindle organization GO:0007051 253 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
ras protein signal transduction GO:0007265 88 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
multi multicellular organism process GO:0044706 123 0.013
glycerolipid catabolic process GO:0046503 3 0.013
vitamin biosynthetic process GO:0009110 1 0.013
activation of innate immune response GO:0002218 4 0.013
fat soluble vitamin metabolic process GO:0006775 1 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
polyol biosynthetic process GO:0046173 3 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
embryonic pattern specification GO:0009880 174 0.013
respiratory system development GO:0060541 213 0.013
response to copper ion GO:0046688 4 0.013
blastoderm segmentation GO:0007350 159 0.013
axis specification GO:0009798 167 0.013
synaptic transmission GO:0007268 288 0.013
defense response to bacterium GO:0042742 178 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
triglyceride biosynthetic process GO:0019432 2 0.012
chromosome organization GO:0051276 360 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
cell recognition GO:0008037 102 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
response to mercury ion GO:0046689 3 0.012
regulation of organelle organization GO:0033043 196 0.012
regulation of catabolic process GO:0009894 170 0.012
cellular lipid metabolic process GO:0044255 83 0.012
regulation of sequestering of triglyceride GO:0010889 3 0.012
tissue death GO:0016271 102 0.012
monocarboxylic acid transport GO:0015718 3 0.012
central nervous system development GO:0007417 201 0.012
regulation of cell cycle process GO:0010564 181 0.012
mitotic nuclear division GO:0007067 213 0.012
response to light stimulus GO:0009416 124 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
peptide metabolic process GO:0006518 80 0.012
organophosphate catabolic process GO:0046434 112 0.012
anterior posterior pattern specification GO:0009952 136 0.012
protein phosphorylation GO:0006468 169 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
vitamin metabolic process GO:0006766 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
positive regulation of molecular function GO:0044093 136 0.012
retina development in camera type eye GO:0060041 4 0.012
digestive tract morphogenesis GO:0048546 127 0.012
cell division GO:0051301 248 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
maintenance of location GO:0051235 73 0.012
rna processing GO:0006396 147 0.012
cation transport GO:0006812 110 0.012
positive regulation of lipid storage GO:0010884 4 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
macromolecule catabolic process GO:0009057 161 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
lauric acid metabolic process GO:0048252 1 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
medium chain fatty acid metabolic process GO:0051791 1 0.012
l amino acid import GO:0043092 2 0.012
salivary gland histolysis GO:0035070 88 0.012
sensory perception GO:0007600 196 0.012
chemosensory behavior GO:0007635 106 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of response to external stimulus GO:0032101 115 0.012
muscle structure development GO:0061061 224 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
regulation of notch signaling pathway GO:0008593 100 0.011
dendrite development GO:0016358 204 0.011
response to endogenous stimulus GO:0009719 119 0.011
cellular protein localization GO:0034613 160 0.011
embryonic morphogenesis GO:0048598 206 0.011
tripartite regional subdivision GO:0007351 103 0.011
locomotory behavior GO:0007626 176 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cellular response to organic substance GO:0071310 132 0.011
response to alcohol GO:0097305 95 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
actin cytoskeleton organization GO:0030036 206 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
chaeta development GO:0022416 97 0.011
acetate ester metabolic process GO:1900619 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
establishment of protein localization GO:0045184 163 0.011
imaginal disc pattern formation GO:0007447 91 0.011
apoptotic process GO:0006915 159 0.011
regulation of immune response GO:0050776 118 0.011
response to starvation GO:0042594 97 0.011
protein complex biogenesis GO:0070271 201 0.011
cholesterol transport GO:0030301 2 0.011
nephron development GO:0072006 3 0.011
dna metabolic process GO:0006259 227 0.011
cytoplasmic transport GO:0016482 130 0.011
peptidyl amino acid modification GO:0018193 105 0.011
Rat
positive regulation of catabolic process GO:0009896 105 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
regulation of lipid transport GO:0032368 3 0.011
eggshell formation GO:0030703 105 0.011
regulation of cellular localization GO:0060341 136 0.011
regulation of hydrolase activity GO:0051336 97 0.011
autophagic cell death GO:0048102 83 0.011
regulation of gene silencing GO:0060968 63 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
sulfur compound metabolic process GO:0006790 59 0.011
regulation of cell death GO:0010941 173 0.011
somatic muscle development GO:0007525 66 0.011
epithelium migration GO:0090132 148 0.011
leg disc development GO:0035218 92 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
multicellular organismal aging GO:0010259 140 0.011
response to organic cyclic compound GO:0014070 89 0.011
meiotic cell cycle process GO:1903046 132 0.011
triglyceride catabolic process GO:0019433 3 0.011
spermatid differentiation GO:0048515 114 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
mitotic cell cycle phase transition GO:0044772 138 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
protein complex assembly GO:0006461 200 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
sensory perception of smell GO:0007608 80 0.010
cell cycle phase transition GO:0044770 140 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
innate immune response activating signal transduction GO:0002758 2 0.010
chromatin organization GO:0006325 207 0.010
reproductive behavior GO:0019098 122 0.010
phosphate ion transport GO:0006817 4 0.010
mesenchymal cell development GO:0014031 1 0.010
histolysis GO:0007559 102 0.010
regulation of phosphorylation GO:0042325 147 0.010
eggshell chorion assembly GO:0007306 66 0.010
embryonic axis specification GO:0000578 107 0.010
synaptic target recognition GO:0008039 45 0.010
secondary metabolic process GO:0019748 75 0.010
meiotic cell cycle GO:0051321 171 0.010
tissue migration GO:0090130 155 0.010
protein processing GO:0016485 68 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
response to nitrogen compound GO:1901698 90 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
spinal cord development GO:0021510 1 0.010
mapk cascade GO:0000165 107 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
insecticide catabolic process GO:0046701 1 0.010

PH4alphaSG2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
cardiovascular system disease DOID:1287 0 0.021
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.015
acquired metabolic disease DOID:0060158 0 0.014
diabetes mellitus DOID:9351 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.013
glucose metabolism disease DOID:4194 0 0.013
type 2 diabetes mellitus DOID:9352 0 0.013
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013
hypertension DOID:10763 0 0.013
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.011
essential hypertension DOID:10825 0 0.011