Drosophila melanogaster

16 known processes

DptB (Dmel_CG10794)

Diptericin B

(Aliases: Diptericin,dptlp,Dmel\CG10794,BcDNA:RH29451,147473_at,CG10794)

DptB biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
antibacterial humoral response GO:0019731 44 0.999
Fly
defense response to gram positive bacterium GO:0050830 41 0.999
antifungal humoral response GO:0019732 12 0.997
humoral immune response GO:0006959 117 0.986
positive regulation of antibacterial peptide production GO:0002803 20 0.979
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.972
regulation of defense response GO:0031347 102 0.971
Fly
antibacterial peptide biosynthetic process GO:0002780 22 0.966
immune response GO:0006955 246 0.964
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.960
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.957
positive regulation of defense response GO:0031349 59 0.956
Fly
regulation of antibacterial peptide production GO:0002786 22 0.951
positive regulation of antimicrobial humoral response GO:0002760 28 0.941
positive regulation of antimicrobial peptide production GO:0002225 28 0.935
response to bacterium GO:0009617 198 0.934
antibacterial peptide production GO:0002778 22 0.932
glycosaminoglycan catabolic process GO:0006027 3 0.928
defense response to gram negative bacterium GO:0050829 94 0.923
Fly
defense response to other organism GO:0098542 225 0.922
antimicrobial humoral response GO:0019730 99 0.918
Fly
positive regulation of defense response to bacterium GO:1900426 23 0.918
regulation of immune response GO:0050776 118 0.915
Fly
defense response to bacterium GO:0042742 178 0.915
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.913
innate immune response GO:0045087 144 0.910
Fly
positive regulation of immune response GO:0050778 63 0.909
Fly
antimicrobial peptide production GO:0002775 46 0.909
activation of innate immune response GO:0002218 4 0.905
defense response GO:0006952 300 0.902
regulation of defense response to bacterium GO:1900424 30 0.897
pattern recognition receptor signaling pathway GO:0002221 2 0.897
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.877
response to external biotic stimulus GO:0043207 293 0.846
regulation of response to stress GO:0080134 200 0.838
Fly
immune system process GO:0002376 347 0.835
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.826
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.818
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.815
peptide metabolic process GO:0006518 80 0.799
regulation of antimicrobial peptide production GO:0002784 44 0.795
response to other organism GO:0051707 293 0.790
positive regulation of immune system process GO:0002684 68 0.779
Fly
response to biotic stimulus GO:0009607 294 0.765
regulation of immune system process GO:0002682 176 0.764
Fly
defense response to virus GO:0051607 23 0.757
innate immune response activating signal transduction GO:0002758 2 0.692
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.678
response to peptidoglycan GO:0032494 2 0.677
positive regulation of response to biotic stimulus GO:0002833 31 0.676
peptidoglycan catabolic process GO:0009253 3 0.661
amide biosynthetic process GO:0043604 42 0.647
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.645
antimicrobial peptide biosynthetic process GO:0002777 38 0.641
defense response to fungus GO:0050832 48 0.613
positive regulation of response to stimulus GO:0048584 323 0.606
Fly
peptidoglycan metabolic process GO:0000270 3 0.601
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.594
regulation of innate immune response GO:0045088 71 0.582
Fly
positive regulation of biosynthetic process GO:0009891 316 0.581
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.525
positive regulation of immune effector process GO:0002699 28 0.511
melanization defense response GO:0035006 45 0.499
salivary gland morphogenesis GO:0007435 145 0.456
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.371
regulation of response to biotic stimulus GO:0002831 63 0.362
secondary metabolic process GO:0019748 75 0.351
cellular response to lipopolysaccharide GO:0071222 3 0.303
response to lipopolysaccharide GO:0032496 4 0.283
phosphorylation GO:0016310 294 0.267
peptide biosynthetic process GO:0043043 42 0.262
cellular response to molecule of bacterial origin GO:0071219 3 0.257
positive regulation of cellular amide metabolic process GO:0034250 26 0.215
mapk cascade GO:0000165 107 0.212
response to molecule of bacterial origin GO:0002237 7 0.182
positive regulation of cellular biosynthetic process GO:0031328 316 0.171
negative regulation of defense response GO:0031348 35 0.163
positive regulation of humoral immune response GO:0002922 28 0.147
immune response activating signal transduction GO:0002757 2 0.145
response to oxygen containing compound GO:1901700 200 0.144
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.142
gland morphogenesis GO:0022612 145 0.140
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.138
regulation of humoral immune response GO:0002920 51 0.135
organonitrogen compound catabolic process GO:1901565 128 0.126
organic substance catabolic process GO:1901575 308 0.114
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.113
regulation of antimicrobial humoral response GO:0002759 50 0.113
negative regulation of response to stimulus GO:0048585 258 0.109
aminoglycan metabolic process GO:0006022 18 0.105
regulation of multi organism process GO:0043900 131 0.100
organonitrogen compound biosynthetic process GO:1901566 117 0.099
negative regulation of intracellular signal transduction GO:1902532 57 0.099
negative regulation of defense response to bacterium GO:1900425 7 0.095
cellular response to oxygen containing compound GO:1901701 79 0.089
positive regulation of innate immune response GO:0045089 38 0.088
Fly
positive regulation of multi organism process GO:0043902 40 0.087
death GO:0016265 284 0.085
negative regulation of innate immune response GO:0045824 30 0.069
response to virus GO:0009615 28 0.067
tissue death GO:0016271 102 0.064
organonitrogen compound metabolic process GO:1901564 318 0.063
aging GO:0007568 143 0.061
carbohydrate derivative metabolic process GO:1901135 217 0.059
negative regulation of signaling GO:0023057 219 0.059
gland development GO:0048732 191 0.058
intracellular signal transduction GO:0035556 300 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.049
negative regulation of cell communication GO:0010648 223 0.047
developmental programmed cell death GO:0010623 138 0.045
cell death GO:0008219 279 0.044
immune response regulating signaling pathway GO:0002764 2 0.044
production of molecular mediator of immune response GO:0002440 46 0.042
programmed cell death GO:0012501 257 0.042
cellular response to biotic stimulus GO:0071216 4 0.042
exocrine system development GO:0035272 162 0.042
regulation of melanization defense response GO:0035007 6 0.041
wing disc morphogenesis GO:0007472 344 0.040
autophagic cell death GO:0048102 83 0.037
immune effector process GO:0002252 98 0.037
response to organic substance GO:0010033 284 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.033
response to fungus GO:0009620 50 0.032
regulation of mapk cascade GO:0043408 92 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
appendage morphogenesis GO:0035107 397 0.031
pigment metabolic process GO:0042440 84 0.029
imaginal disc derived appendage development GO:0048737 399 0.028
cellular amide metabolic process GO:0043603 80 0.027
catabolic process GO:0009056 409 0.027
stress activated mapk cascade GO:0051403 52 0.027
body morphogenesis GO:0010171 2 0.027
appendage development GO:0048736 401 0.027
macromolecule catabolic process GO:0009057 161 0.027
negative regulation of signal transduction GO:0009968 206 0.027
salivary gland development GO:0007431 162 0.027
protein modification process GO:0036211 438 0.026
regulation of phosphorylation GO:0042325 147 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
determination of adult lifespan GO:0008340 137 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
regulation of cellular amide metabolic process GO:0034248 39 0.022
response to endogenous stimulus GO:0009719 119 0.022
salivary gland histolysis GO:0035070 88 0.022
amine metabolic process GO:0009308 12 0.022
signal transduction by phosphorylation GO:0023014 107 0.021
nuclear division GO:0000280 332 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.020
cellular ketone metabolic process GO:0042180 24 0.020
cellular catabolic process GO:0044248 372 0.020
detection of chemical stimulus GO:0009593 93 0.020
anion homeostasis GO:0055081 3 0.019
regionalization GO:0003002 416 0.019
negative regulation of phosphate metabolic process GO:0045936 45 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
positive regulation of gene expression GO:0010628 290 0.019
histolysis GO:0007559 102 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
kidney development GO:0001822 3 0.018
single organism catabolic process GO:0044712 228 0.018
developmental growth GO:0048589 280 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
camera type eye development GO:0043010 4 0.018
cellular protein modification process GO:0006464 438 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
forebrain development GO:0030900 2 0.018
phagocytosis GO:0006909 215 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
positive regulation of response to external stimulus GO:0032103 44 0.017
positive regulation of cell migration GO:0030335 2 0.017
taxis GO:0042330 304 0.017
response to mercury ion GO:0046689 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
growth GO:0040007 359 0.017
positive regulation of cell motility GO:2000147 3 0.017
response to paraquat GO:1901562 4 0.017
response to abiotic stimulus GO:0009628 341 0.017
cellular amine metabolic process GO:0044106 12 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.016
negative regulation of phosphorylation GO:0042326 35 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
regulation of cellular response to stress GO:0080135 89 0.016
organelle fission GO:0048285 340 0.016
xenobiotic catabolic process GO:0042178 1 0.016
jnk cascade GO:0007254 50 0.016
regulation of response to external stimulus GO:0032101 115 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
oxoacid metabolic process GO:0043436 103 0.016
regulation of cell cycle GO:0051726 291 0.016
endocytosis GO:0006897 310 0.015
epithelial cell development GO:0002064 274 0.015
connective tissue development GO:0061448 3 0.015
chromosome organization GO:0051276 360 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
neurological system process GO:0050877 358 0.015
organic acid metabolic process GO:0006082 103 0.015
stress activated protein kinase signaling cascade GO:0031098 55 0.015
negative regulation of developmental process GO:0051093 201 0.015
multicellular organismal aging GO:0010259 140 0.015
segmentation GO:0035282 207 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
synaptic transmission GO:0007268 288 0.015
positive regulation of cell communication GO:0010647 250 0.015
axis specification GO:0009798 167 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
response to radiation GO:0009314 155 0.014
response to nitrogen compound GO:1901698 90 0.014
mitotic nuclear division GO:0007067 213 0.014
small molecule metabolic process GO:0044281 305 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
positive regulation of signal transduction GO:0009967 223 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.014
hindbrain development GO:0030902 2 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
disruption of cells of other organism GO:0044364 1 0.014
chemotaxis GO:0006935 249 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
vesicle mediated transport GO:0016192 381 0.013
fat soluble vitamin metabolic process GO:0006775 1 0.013
telencephalon development GO:0021537 2 0.013
vitamin biosynthetic process GO:0009110 1 0.013
regulation of nervous system development GO:0051960 248 0.013
macromolecular complex assembly GO:0065003 256 0.013
organelle assembly GO:0070925 198 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
axon development GO:0061564 297 0.013
sterol homeostasis GO:0055092 4 0.013
cholesterol homeostasis GO:0042632 3 0.013
single organism behavior GO:0044708 391 0.013
homeostatic process GO:0042592 199 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
polyol biosynthetic process GO:0046173 3 0.013
negative regulation of gene expression GO:0010629 387 0.013
response to hexose GO:0009746 3 0.013
response to glucose GO:0009749 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
cell adhesion GO:0007155 136 0.013
establishment of localization in cell GO:0051649 402 0.013
ovarian follicle cell development GO:0030707 248 0.013
blastoderm segmentation GO:0007350 159 0.013
heterocycle catabolic process GO:0046700 166 0.012
eye development GO:0001654 323 0.012
kidney epithelium development GO:0072073 3 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
response to organophosphorus GO:0046683 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
protein localization GO:0008104 284 0.012
regulation of anatomical structure size GO:0090066 163 0.012
epithelial cell differentiation GO:0030855 322 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
regulation of catalytic activity GO:0050790 185 0.012
limb development GO:0060173 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
adult behavior GO:0030534 137 0.012
regulation of jnk cascade GO:0046328 40 0.012
intracellular transport GO:0046907 228 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
camera type eye morphogenesis GO:0048593 2 0.012
chaeta development GO:0022416 97 0.012
regulation of developmental growth GO:0048638 174 0.012
maintenance of location GO:0051235 73 0.012
protein phosphorylation GO:0006468 169 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
developmental maturation GO:0021700 172 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
protein complex biogenesis GO:0070271 201 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
single organism intracellular transport GO:1902582 207 0.011
positive regulation of lipid storage GO:0010884 4 0.011
organophosphate metabolic process GO:0019637 195 0.011
melanin metabolic process GO:0006582 47 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
nephron tubule development GO:0072080 3 0.011
rna processing GO:0006396 147 0.011
regulation of growth GO:0040008 233 0.011
insecticide metabolic process GO:0017143 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
glucosamine containing compound catabolic process GO:1901072 3 0.011
steroid catabolic process GO:0006706 1 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
regulation of protein metabolic process GO:0051246 256 0.011
ion transport GO:0006811 145 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
meiotic cell cycle GO:0051321 171 0.011
androgen metabolic process GO:0008209 1 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
nephron development GO:0072006 3 0.011
positive regulation of sequestering of triglyceride GO:0010890 1 0.011
cytolysis GO:0019835 1 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
limb morphogenesis GO:0035108 1 0.011
compound eye development GO:0048749 307 0.011
cell cycle phase transition GO:0044770 140 0.011
cellular response to organic substance GO:0071310 132 0.011
embryonic pattern specification GO:0009880 174 0.011
response to pain GO:0048265 3 0.011
nephron epithelium development GO:0072009 3 0.011
cellular macromolecule localization GO:0070727 220 0.011
vitamin metabolic process GO:0006766 2 0.011
killing of cells of other organism GO:0031640 1 0.011
response to light stimulus GO:0009416 124 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of mitotic cell cycle GO:0007346 190 0.010
retina development in camera type eye GO:0060041 4 0.010
nucleoside metabolic process GO:0009116 127 0.010
regulation of cell death GO:0010941 173 0.010
transmembrane transport GO:0055085 139 0.010
rrna processing GO:0006364 3 0.010
purine containing compound metabolic process GO:0072521 155 0.010
mrna metabolic process GO:0016071 124 0.010
axonogenesis GO:0007409 290 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
kidney morphogenesis GO:0060993 3 0.010
single organism biosynthetic process GO:0044711 206 0.010
response to copper ion GO:0046688 4 0.010
cell proliferation GO:0008283 299 0.010
anatomical structure homeostasis GO:0060249 97 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
spindle organization GO:0007051 253 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
embryonic axis specification GO:0000578 107 0.010
negative regulation of immune system process GO:0002683 50 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010

DptB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017
artery disease DOID:0050828 0 0.015
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
urinary system disease DOID:18 0 0.011
musculoskeletal system disease DOID:17 0 0.011