Drosophila melanogaster

119 known processes

Mkp3 (Dmel_CG14080)

Mitogen-activated protein kinase phosphatase 3

(Aliases: mkp3,DMKP-3,MKP3,Dmkp3,Dmel\CG14080,CG14080,CG14081)

Mkp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived wing morphogenesis GO:0007476 337 0.955
appendage morphogenesis GO:0035107 397 0.938
imaginal disc derived appendage morphogenesis GO:0035114 395 0.936
appendage development GO:0048736 401 0.933
regulation of nervous system development GO:0051960 248 0.880
imaginal disc derived appendage development GO:0048737 399 0.875
wing disc morphogenesis GO:0007472 344 0.861
post embryonic appendage morphogenesis GO:0035120 385 0.790
regulation of neuron differentiation GO:0045664 103 0.752
regulation of neurogenesis GO:0050767 158 0.707
negative regulation of cell communication GO:0010648 223 0.688
renal system development GO:0072001 72 0.657
cortical actin cytoskeleton organization GO:0030866 24 0.642
epithelial cell migration GO:0010631 148 0.635
embryonic morphogenesis GO:0048598 206 0.624
Zebrafish
open tracheal system development GO:0007424 204 0.621
sensory organ morphogenesis GO:0090596 260 0.583
morphogenesis of an epithelium GO:0002009 276 0.565
photoreceptor cell differentiation GO:0046530 170 0.540
ovarian follicle cell development GO:0030707 248 0.520
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.487
intracellular signal transduction GO:0035556 300 0.485
tube development GO:0035295 244 0.480
tor signaling GO:0031929 32 0.480
urogenital system development GO:0001655 72 0.479
programmed cell death GO:0012501 257 0.471
Human
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.463
negative regulation of signal transduction GO:0009968 206 0.449
regulation of cell development GO:0060284 215 0.442
enzyme linked receptor protein signaling pathway GO:0007167 179 0.435
Zebrafish
cortical cytoskeleton organization GO:0030865 29 0.431
chorion containing eggshell formation GO:0007304 105 0.421
regulation of growth GO:0040008 233 0.404
Mouse
defense response GO:0006952 300 0.398
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.395
negative regulation of signaling GO:0023057 219 0.391
cell motility GO:0048870 251 0.390
transcription from rna polymerase ii promoter GO:0006366 368 0.384
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.382
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.365
response to light stimulus GO:0009416 124 0.363
defense response to other organism GO:0098542 225 0.359
epithelial cell development GO:0002064 274 0.345
response to radiation GO:0009314 155 0.344
small gtpase mediated signal transduction GO:0007264 88 0.342
compound eye development GO:0048749 307 0.333
regulation of anatomical structure morphogenesis GO:0022603 242 0.330
Zebrafish
rho protein signal transduction GO:0007266 14 0.324
response to external biotic stimulus GO:0043207 293 0.322
negative regulation of rna metabolic process GO:0051253 251 0.317
eye morphogenesis GO:0048592 260 0.317
ovarian follicle cell migration GO:0007297 121 0.305
regulation of organ morphogenesis GO:2000027 78 0.298
localization of cell GO:0051674 257 0.290
actin filament based process GO:0030029 220 0.289
compound eye photoreceptor fate commitment GO:0001752 36 0.283
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.279
positive regulation of ras gtpase activity GO:0032320 36 0.277
catabolic process GO:0009056 409 0.274
erbb signaling pathway GO:0038127 58 0.270
negative regulation of cellular metabolic process GO:0031324 382 0.269
regulation of phosphate metabolic process GO:0019220 210 0.269
tissue morphogenesis GO:0048729 297 0.267
border follicle cell migration GO:0007298 113 0.266
regulation of cell proliferation GO:0042127 163 0.255
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.254
regulation of cellular amine metabolic process GO:0033238 3 0.251
epithelium migration GO:0090132 148 0.249
r7 cell differentiation GO:0045466 43 0.246
tube morphogenesis GO:0035239 191 0.244
imaginal disc derived wing vein specification GO:0007474 48 0.238
negative regulation of transcription dna templated GO:0045892 237 0.236
regulation of molecular function GO:0065009 217 0.233
Human Mouse
positive regulation of rho gtpase activity GO:0032321 19 0.228
regulation of hydrolase activity GO:0051336 97 0.223
positive regulation of biosynthetic process GO:0009891 316 0.223
compound eye morphogenesis GO:0001745 249 0.223
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.222
regulation of rho protein signal transduction GO:0035023 20 0.216
regulation of gtp catabolic process GO:0033124 44 0.213
dendrite development GO:0016358 204 0.212
regulation of cellular component size GO:0032535 98 0.212
regulation of erbb signaling pathway GO:1901184 42 0.212
death GO:0016265 284 0.209
Human
ras protein signal transduction GO:0007265 88 0.204
regulation of photoreceptor cell differentiation GO:0046532 34 0.202
stem cell differentiation GO:0048863 117 0.201
response to organic substance GO:0010033 284 0.194
Zebrafish
organonitrogen compound metabolic process GO:1901564 318 0.194
positive regulation of cellular biosynthetic process GO:0031328 316 0.187
positive regulation of transcription dna templated GO:0045893 266 0.186
regulation of cell differentiation GO:0045595 302 0.186
Zebrafish
positive regulation of response to stimulus GO:0048584 323 0.186
response to abiotic stimulus GO:0009628 341 0.182
regulation of small gtpase mediated signal transduction GO:0051056 93 0.182
columnar cuboidal epithelial cell development GO:0002066 249 0.179
eye development GO:0001654 323 0.179
positive regulation of cell communication GO:0010647 250 0.177
small molecule metabolic process GO:0044281 305 0.177
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.175
positive regulation of signaling GO:0023056 243 0.172
oocyte construction GO:0007308 112 0.169
phosphorylation GO:0016310 294 0.167
multicellular organismal aging GO:0010259 140 0.164
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.162
digestive tract morphogenesis GO:0048546 127 0.158
Zebrafish
regulation of cell projection organization GO:0031344 92 0.158
epithelial cell differentiation GO:0030855 322 0.156
tissue migration GO:0090130 155 0.155
aging GO:0007568 143 0.154
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.153
axon development GO:0061564 297 0.153
regulation of catalytic activity GO:0050790 185 0.152
Human Mouse
cell projection assembly GO:0030031 94 0.152
oocyte development GO:0048599 124 0.151
cell maturation GO:0048469 144 0.151
germarium derived egg chamber formation GO:0007293 101 0.147
digestive tract development GO:0048565 149 0.144
Zebrafish
compound eye photoreceptor cell differentiation GO:0001751 140 0.143
regulation of cellular catabolic process GO:0031329 157 0.143
regulation of immune response GO:0050776 118 0.142
single organism cellular localization GO:1902580 180 0.142
single organism behavior GO:0044708 391 0.140
respiratory system development GO:0060541 213 0.140
establishment of localization in cell GO:0051649 402 0.134
positive regulation of catalytic activity GO:0043085 118 0.134
oocyte differentiation GO:0009994 145 0.134
determination of adult lifespan GO:0008340 137 0.133
mitotic cell cycle phase transition GO:0044772 138 0.131
proteolysis GO:0006508 192 0.130
eggshell chorion assembly GO:0007306 66 0.128
axis specification GO:0009798 167 0.128
gastrulation GO:0007369 70 0.127
Zebrafish
regulation of ras protein signal transduction GO:0046578 93 0.125
regulation of ras gtpase activity GO:0032318 38 0.125
positive regulation of gtpase activity GO:0043547 43 0.125
regulation of protein metabolic process GO:0051246 256 0.125
Human Mouse
regulation of intracellular signal transduction GO:1902531 236 0.124
positive regulation of hydrolase activity GO:0051345 78 0.123
epithelial tube morphogenesis GO:0060562 88 0.122
forebrain development GO:0030900 2 0.120
neurological system process GO:0050877 358 0.119
positive regulation of macromolecule metabolic process GO:0010604 405 0.118
immune response GO:0006955 246 0.116
developmental growth GO:0048589 280 0.116
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.116
eggshell formation GO:0030703 105 0.115
head involution GO:0008258 35 0.115
oocyte axis specification GO:0007309 108 0.114
positive regulation of developmental process GO:0051094 143 0.114
regulation of cellular protein metabolic process GO:0032268 243 0.110
Human Mouse
negative regulation of cellular catabolic process GO:0031330 34 0.109
ameboidal type cell migration GO:0001667 151 0.108
multicellular organism growth GO:0035264 46 0.107
embryonic development via the syncytial blastoderm GO:0001700 148 0.107
regulation of cellular amino acid metabolic process GO:0006521 0 0.105
apoptotic process GO:0006915 159 0.104
Human
cell death GO:0008219 279 0.102
Human
regulation of endopeptidase activity GO:0052548 36 0.099
chromosome organization GO:0051276 360 0.098
response to oxidative stress GO:0006979 86 0.097
regulation of phosphorus metabolic process GO:0051174 210 0.097
adult behavior GO:0030534 137 0.097
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.096
negative regulation of intracellular signal transduction GO:1902532 57 0.096
positive regulation of nucleic acid templated transcription GO:1903508 266 0.095
cellular component assembly involved in morphogenesis GO:0010927 151 0.095
regulation of neuron projection development GO:0010975 69 0.095
locomotory behavior GO:0007626 176 0.094
growth GO:0040007 359 0.093
Mouse
negative regulation of cell development GO:0010721 62 0.091
negative regulation of nucleic acid templated transcription GO:1903507 240 0.091
protein complex assembly GO:0006461 200 0.090
negative regulation of erbb signaling pathway GO:1901185 29 0.089
regulation of cell death GO:0010941 173 0.088
Human
regulation of immune system process GO:0002682 176 0.088
positive regulation of signal transduction GO:0009967 223 0.087
cellular protein modification process GO:0006464 438 0.087
negative regulation of phosphate metabolic process GO:0045936 45 0.085
positive regulation of rna biosynthetic process GO:1902680 266 0.085
cellular response to external stimulus GO:0071496 66 0.085
regulation of protein kinase activity GO:0045859 51 0.085
Human Mouse
eye photoreceptor cell fate commitment GO:0042706 37 0.084
eye photoreceptor cell differentiation GO:0001754 145 0.084
positive regulation of phosphorus metabolic process GO:0010562 139 0.084
regulation of cell morphogenesis GO:0022604 163 0.084
regulation of cell cycle GO:0051726 291 0.084
positive regulation of nucleoside metabolic process GO:0045979 47 0.082
negative regulation of biosynthetic process GO:0009890 277 0.082
axon choice point recognition GO:0016198 26 0.081
regulation of nucleotide metabolic process GO:0006140 62 0.080
embryo development ending in birth or egg hatching GO:0009792 152 0.079
oxoacid metabolic process GO:0043436 103 0.079
cellular response to dna damage stimulus GO:0006974 223 0.078
regulation of anatomical structure size GO:0090066 163 0.078
regulation of gtpase activity GO:0043087 44 0.078
ventral cord development GO:0007419 16 0.077
cell migration GO:0016477 238 0.077
defense response to bacterium GO:0042742 178 0.077
guanosine containing compound metabolic process GO:1901068 74 0.076
regulation of membrane potential GO:0042391 35 0.075
regulation of developmental growth GO:0048638 174 0.074
Mouse
neuron fate commitment GO:0048663 50 0.074
positive regulation of immune system process GO:0002684 68 0.072
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.072
epidermal growth factor receptor signaling pathway GO:0007173 58 0.071
hindgut morphogenesis GO:0007442 58 0.071
convergent extension GO:0060026 2 0.068
digestive system development GO:0055123 149 0.068
Zebrafish
regulation of kinase activity GO:0043549 53 0.067
Human Mouse
neuron projection guidance GO:0097485 241 0.067
genital disc development GO:0035215 44 0.067
skin development GO:0043588 65 0.067
neuromuscular junction development GO:0007528 149 0.066
cellular ketone metabolic process GO:0042180 24 0.066
regulation of purine nucleotide catabolic process GO:0033121 48 0.065
positive regulation of cell proliferation GO:0008284 47 0.065
negative regulation of gene expression GO:0010629 387 0.065
gland development GO:0048732 191 0.065
torc1 signaling GO:0038202 12 0.064
hindgut development GO:0061525 58 0.064
cellular amino acid metabolic process GO:0006520 61 0.064
positive regulation of molecular function GO:0044093 136 0.063
regulation of localization GO:0032879 275 0.063
muscle structure development GO:0061061 224 0.062
myotube differentiation GO:0014902 46 0.062
photoreceptor cell fate commitment GO:0046552 41 0.061
cell proliferation GO:0008283 299 0.060
negative regulation of response to stimulus GO:0048585 258 0.059
regulation of multicellular organismal development GO:2000026 414 0.058
Zebrafish Mouse
vesicle mediated transport GO:0016192 381 0.058
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.058
eye antennal disc morphogenesis GO:0007455 34 0.056
regulation of erk1 and erk2 cascade GO:0070372 39 0.055
Human
amine metabolic process GO:0009308 12 0.055
dendrite morphogenesis GO:0048813 199 0.055
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.055
actin cytoskeleton organization GO:0030036 206 0.054
protein phosphorylation GO:0006468 169 0.054
Human Mouse
cell recognition GO:0008037 102 0.054
mapk cascade GO:0000165 107 0.054
kidney development GO:0001822 3 0.053
tracheal outgrowth open tracheal system GO:0007426 18 0.053
morphogenesis of a branching epithelium GO:0061138 45 0.053
leg disc development GO:0035218 92 0.053
morphogenesis of embryonic epithelium GO:0016331 94 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
positive regulation of nucleotide metabolic process GO:0045981 55 0.051
cell cell signaling involved in cell fate commitment GO:0045168 210 0.050
regionalization GO:0003002 416 0.050
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.050
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.050
regulation of phosphorylation GO:0042325 147 0.050
synaptic growth at neuromuscular junction GO:0051124 119 0.050
regulation of transposition rna mediated GO:0010525 3 0.049
protein complex biogenesis GO:0070271 201 0.049
regulation of protein phosphorylation GO:0001932 64 0.049
Human Mouse
positive regulation of gene expression GO:0010628 290 0.049
single organism intracellular transport GO:1902582 207 0.048
nucleotide metabolic process GO:0009117 161 0.048
transposition rna mediated GO:0032197 3 0.047
eye antennal disc development GO:0035214 60 0.046
erk1 and erk2 cascade GO:0070371 39 0.045
Human
negative regulation of cellular biosynthetic process GO:0031327 277 0.045
intracellular transport GO:0046907 228 0.045
negative regulation of cell differentiation GO:0045596 143 0.045
cellular amine metabolic process GO:0044106 12 0.044
positive regulation of protein metabolic process GO:0051247 128 0.043
gtp catabolic process GO:0006184 72 0.043
protein maturation GO:0051604 71 0.042
embryonic axis specification GO:0000578 107 0.042
body morphogenesis GO:0010171 2 0.042
regulation of organelle organization GO:0033043 196 0.042
regulation of purine nucleotide metabolic process GO:1900542 62 0.041
peptidyl threonine phosphorylation GO:0018107 2 0.041
stem cell fate commitment GO:0048865 25 0.040
peripheral nervous system development GO:0007422 52 0.040
response to alcohol GO:0097305 95 0.040
malpighian tubule morphogenesis GO:0007443 44 0.040
axon guidance GO:0007411 233 0.040
regulation of nucleoside metabolic process GO:0009118 50 0.039
synapse assembly GO:0007416 143 0.039
cell adhesion GO:0007155 136 0.039
guanosine containing compound catabolic process GO:1901069 74 0.039
cellular response to organonitrogen compound GO:0071417 36 0.039
synapse organization GO:0050808 196 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.038
exocrine system development GO:0035272 162 0.038
dephosphorylation GO:0016311 51 0.038
neuron recognition GO:0008038 101 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.037
Zebrafish
endocytosis GO:0006897 310 0.037
immune system development GO:0002520 57 0.037
regulation of cellular ketone metabolic process GO:0010565 3 0.037
regulation of response to stress GO:0080134 200 0.037
branching involved in open tracheal system development GO:0060446 45 0.037
cognition GO:0050890 141 0.037
protein import into nucleus GO:0006606 51 0.037
negative regulation of multicellular organismal process GO:0051241 142 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
cation transmembrane transport GO:0098655 88 0.036
regulation of nucleotide catabolic process GO:0030811 48 0.036
positive regulation of cellular catabolic process GO:0031331 95 0.036
positive regulation of nucleotide catabolic process GO:0030813 46 0.036
purine nucleoside triphosphate catabolic process GO:0009146 108 0.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.035
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.035
nucleoside metabolic process GO:0009116 127 0.035
positive regulation of cell death GO:0010942 69 0.035
Human
macromolecular complex assembly GO:0065003 256 0.035
homeostatic process GO:0042592 199 0.034
regulation of response to external stimulus GO:0032101 115 0.034
positive regulation of cellular component organization GO:0051130 156 0.034
negative regulation of nervous system development GO:0051961 92 0.034
positive regulation of intracellular signal transduction GO:1902533 116 0.034
myotube cell development GO:0014904 3 0.034
hemopoiesis GO:0030097 46 0.034
regulation of apoptotic process GO:0042981 130 0.034
Human
endodermal cell fate commitment GO:0001711 3 0.034
Zebrafish
regulation of apoptotic signaling pathway GO:2001233 10 0.033
dorsal closure GO:0007391 79 0.033
response to oxygen containing compound GO:1901700 200 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
Zebrafish
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
cellular response to endogenous stimulus GO:0071495 80 0.033
Zebrafish
developmental cell growth GO:0048588 52 0.033
cytokinesis GO:0000910 90 0.033
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.032
Human
positive regulation of apoptotic process GO:0043065 47 0.032
Human
positive regulation of gtp catabolic process GO:0033126 43 0.032
head development GO:0060322 135 0.032
negative regulation of phosphorus metabolic process GO:0010563 45 0.032
cell division GO:0051301 248 0.032
regulation of cell size GO:0008361 63 0.032
jak stat cascade GO:0007259 49 0.032
positive regulation of phosphate metabolic process GO:0045937 139 0.031
establishment or maintenance of cell polarity GO:0007163 167 0.031
response to other organism GO:0051707 293 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
single organism cell adhesion GO:0098602 47 0.031
cellular response to mechanical stimulus GO:0071260 2 0.031
regulation of cell adhesion GO:0030155 27 0.030
anatomical structure homeostasis GO:0060249 97 0.030
golgi vesicle transport GO:0048193 27 0.030
peptidyl amino acid modification GO:0018193 105 0.030
salivary gland development GO:0007431 162 0.030
secretion by cell GO:0032940 101 0.029
gtp metabolic process GO:0046039 72 0.029
activation of mapk activity GO:0000187 9 0.029
immune response activating signal transduction GO:0002757 2 0.029
cellular response to extracellular stimulus GO:0031668 64 0.029
positive regulation of multicellular organismal process GO:0051240 143 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.028
innate immune response GO:0045087 144 0.028
negative regulation of developmental process GO:0051093 201 0.028
organic acid metabolic process GO:0006082 103 0.028
regulation of actin filament polymerization GO:0030833 25 0.028
heterocycle catabolic process GO:0046700 166 0.028
negative regulation of peptide secretion GO:0002792 1 0.028
reproductive system development GO:0061458 74 0.028
development of primary sexual characteristics GO:0045137 50 0.028
cell cycle phase transition GO:0044770 140 0.028
regulation of epidermal growth factor activated receptor activity GO:0007176 4 0.028
developmental growth involved in morphogenesis GO:0060560 65 0.027
response to bacterium GO:0009617 198 0.027
renal tubule development GO:0061326 64 0.027
axon midline choice point recognition GO:0016199 26 0.027
positive regulation of wound healing GO:0090303 12 0.027
regulation of decapentaplegic signaling pathway GO:0090097 8 0.027
cellular response to organic substance GO:0071310 132 0.027
Zebrafish
negative regulation of programmed cell death GO:0043069 72 0.027
regulation of protein modification process GO:0031399 112 0.026
Human Mouse
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.026
cellular protein localization GO:0034613 160 0.026
developmental maturation GO:0021700 172 0.026
single organism catabolic process GO:0044712 228 0.026
negative regulation of catabolic process GO:0009895 36 0.026
defense response to gram negative bacterium GO:0050829 94 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
salivary gland histolysis GO:0035070 88 0.026
regulation of actin filament based process GO:0032970 42 0.026
maintenance of location GO:0051235 73 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
regulation of synapse structure and activity GO:0050803 128 0.025
actin filament based movement GO:0030048 26 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
positive regulation of catabolic process GO:0009896 105 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
response to organophosphorus GO:0046683 2 0.024
cation transport GO:0006812 110 0.024
apoptotic cell clearance GO:0043277 14 0.024
organic substance catabolic process GO:1901575 308 0.024
ommatidial rotation GO:0016318 20 0.024
nuclear import GO:0051170 51 0.024
positive regulation of neurogenesis GO:0050769 41 0.024
glycosyl compound catabolic process GO:1901658 112 0.024
aromatic compound catabolic process GO:0019439 166 0.024
regulation of synapse assembly GO:0051963 94 0.024
ribonucleoside catabolic process GO:0042454 112 0.023
segmentation GO:0035282 207 0.023
apoptotic signaling pathway GO:0097190 27 0.023
regulation of peptidase activity GO:0052547 39 0.023
immune response regulating signaling pathway GO:0002764 2 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
spiracle morphogenesis open tracheal system GO:0035277 22 0.023
positive regulation of multicellular organism growth GO:0040018 21 0.023
multi organism reproductive behavior GO:0044705 121 0.023
phagocytosis engulfment GO:0006911 11 0.023
embryonic pattern specification GO:0009880 174 0.023
circulatory system development GO:0072359 82 0.023
Mouse
protein catabolic process GO:0030163 101 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.023
regulation of vesicle mediated transport GO:0060627 59 0.023
protein modification process GO:0036211 438 0.023
negative regulation of protein phosphorylation GO:0001933 17 0.023
Human Mouse
stem cell proliferation GO:0072089 88 0.022
negative regulation of phosphorylation GO:0042326 35 0.022
regulation of r7 cell differentiation GO:0045676 15 0.022
actin filament organization GO:0007015 126 0.022
organophosphate catabolic process GO:0046434 112 0.022
negative regulation of ras protein signal transduction GO:0046580 13 0.022
terminal branching open tracheal system GO:0007430 17 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
response to inorganic substance GO:0010035 44 0.022
intracellular mrna localization GO:0008298 66 0.022
cell cycle g1 s phase transition GO:0044843 31 0.022
single organism nuclear import GO:1902593 51 0.022
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.022
neural precursor cell proliferation GO:0061351 75 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.021
epidermal cell differentiation GO:0009913 51 0.021
regulation of synapse organization GO:0050807 110 0.021
regulation of immune effector process GO:0002697 52 0.021
negative regulation of neurogenesis GO:0050768 53 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
response to growth factor GO:0070848 31 0.021
Zebrafish
cellular amide metabolic process GO:0043603 80 0.021
cell migration involved in gastrulation GO:0042074 9 0.021
response to alkaloid GO:0043279 26 0.021
larval development GO:0002164 104 0.021
pole plasm mrna localization GO:0019094 49 0.020
dna metabolic process GO:0006259 227 0.020
phagocytosis GO:0006909 215 0.020
immune system process GO:0002376 347 0.020
developmental programmed cell death GO:0010623 138 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
blastoderm segmentation GO:0007350 159 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
protein processing GO:0016485 68 0.020
regulation of rho gtpase activity GO:0032319 20 0.020
regulation of multicellular organism growth GO:0040014 40 0.020
positive regulation of transferase activity GO:0051347 26 0.020
purine containing compound catabolic process GO:0072523 112 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
r7 cell fate commitment GO:0007465 12 0.019
negative regulation of mapk cascade GO:0043409 23 0.019
organic substance transport GO:0071702 257 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
establishment of ommatidial planar polarity GO:0042067 49 0.019
anterior posterior pattern specification GO:0009952 136 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
germ line cyst formation GO:0048134 44 0.019
negative regulation of rho protein signal transduction GO:0035024 1 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.019
positive regulation of response to wounding GO:1903036 15 0.019
action potential GO:0001508 13 0.019
hair cell differentiation GO:0035315 47 0.019
actin mediated cell contraction GO:0070252 21 0.019
regulation of protein localization GO:0032880 76 0.019
cellular response to nutrient levels GO:0031669 62 0.018
positive regulation of rac gtpase activity GO:0032855 8 0.018
neuron death GO:0070997 27 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
cellular protein complex assembly GO:0043623 71 0.018

Mkp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
cardiovascular system disease DOID:1287 0 0.079
disease of metabolism DOID:0014667 0 0.054
carbohydrate metabolism disease DOID:0050013 0 0.054
glucose metabolism disease DOID:4194 0 0.054
acquired metabolic disease DOID:0060158 0 0.054
diabetes mellitus DOID:9351 0 0.042
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.028
auditory system disease DOID:2742 0 0.024
sensory system disease DOID:0050155 0 0.024
nervous system disease DOID:863 0 0.024
large intestine cancer DOID:5672 0 0.019
gastrointestinal system cancer DOID:3119 0 0.019
intestinal cancer DOID:10155 0 0.019
colorectal cancer DOID:9256 0 0.019