Drosophila melanogaster

33 known processes

RunxA (Dmel_CG34145)

CG34145 gene product from transcript CG34145-RA

(Aliases: CG34145,CG15453,CG1379,Dmel\CG34145)

RunxA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biosynthetic process GO:0009890 277 0.110
Human
organonitrogen compound metabolic process GO:1901564 318 0.097
negative regulation of nucleic acid templated transcription GO:1903507 240 0.094
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.088
negative regulation of gene expression GO:0010629 387 0.088
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.088
Human
positive regulation of gene expression GO:0010628 290 0.079
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.076
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.071
Human
neurological system process GO:0050877 358 0.070
positive regulation of rna biosynthetic process GO:1902680 266 0.064
Human
response to abiotic stimulus GO:0009628 341 0.063
dendrite morphogenesis GO:0048813 199 0.061
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.060
negative regulation of rna metabolic process GO:0051253 251 0.060
Human
negative regulation of cellular biosynthetic process GO:0031327 277 0.058
Human
tissue morphogenesis GO:0048729 297 0.057
small molecule metabolic process GO:0044281 305 0.054
stem cell differentiation GO:0048863 117 0.052
forebrain development GO:0030900 2 0.051
appendage development GO:0048736 401 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.047
Human
positive regulation of biosynthetic process GO:0009891 316 0.044
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.041
Human
positive regulation of transcription dna templated GO:0045893 266 0.041
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.041
Human
developmental maturation GO:0021700 172 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.039
regionalization GO:0003002 416 0.037
dendrite development GO:0016358 204 0.037
negative regulation of developmental process GO:0051093 201 0.036
homeostatic process GO:0042592 199 0.036
appendage morphogenesis GO:0035107 397 0.036
regulation of multicellular organismal development GO:2000026 414 0.034
Rat
oxoacid metabolic process GO:0043436 103 0.033
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
connective tissue development GO:0061448 3 0.031
negative regulation of transcription dna templated GO:0045892 237 0.031
Human
negative regulation of cellular metabolic process GO:0031324 382 0.030
Human
cellular response to chemical stimulus GO:0070887 199 0.030
Rat
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
oocyte differentiation GO:0009994 145 0.030
organic acid metabolic process GO:0006082 103 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.030
single organism biosynthetic process GO:0044711 206 0.029
death GO:0016265 284 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
morphogenesis of an epithelium GO:0002009 276 0.028
multi organism behavior GO:0051705 175 0.028
mesoderm development GO:0007498 78 0.027
body morphogenesis GO:0010171 2 0.027
positive regulation of rna metabolic process GO:0051254 271 0.027
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.026
regulation of cell cycle GO:0051726 291 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
positive regulation of response to stimulus GO:0048584 323 0.025
detection of stimulus GO:0051606 156 0.025
pole plasm rna localization GO:0007316 52 0.024
response to organic substance GO:0010033 284 0.024
Rat
cellular ketone metabolic process GO:0042180 24 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
wing disc morphogenesis GO:0007472 344 0.023
establishment or maintenance of cell polarity GO:0007163 167 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
Human
peripheral nervous system development GO:0007422 52 0.023
oocyte development GO:0048599 124 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
Human
regulation of cell proliferation GO:0042127 163 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
response to inorganic substance GO:0010035 44 0.022
glial cell differentiation GO:0010001 35 0.022
embryonic axis specification GO:0000578 107 0.021
sensory organ morphogenesis GO:0090596 260 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
protein modification process GO:0036211 438 0.021
peptidyl lysine modification GO:0018205 57 0.021
regulation of cell cycle process GO:0010564 181 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.020
cell maturation GO:0048469 144 0.020
catabolic process GO:0009056 409 0.020
negative regulation of gene expression epigenetic GO:0045814 77 0.020
telencephalon development GO:0021537 2 0.020
camera type eye development GO:0043010 4 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
Human
regulation of localization GO:0032879 275 0.020
Rat
regulation of anatomical structure size GO:0090066 163 0.019
spermatogenesis GO:0007283 200 0.019
peptide metabolic process GO:0006518 80 0.019
vitamin metabolic process GO:0006766 2 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
hindbrain development GO:0030902 2 0.019
programmed cell death GO:0012501 257 0.019
negative regulation of cell differentiation GO:0045596 143 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
regulation of gene expression epigenetic GO:0040029 128 0.018
chaeta development GO:0022416 97 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
Human
proteolysis GO:0006508 192 0.018
regulation of programmed cell death GO:0043067 152 0.018
retina development in camera type eye GO:0060041 4 0.018
cell death GO:0008219 279 0.018
limb morphogenesis GO:0035108 1 0.017
regulation of cell differentiation GO:0045595 302 0.017
notch signaling pathway GO:0007219 120 0.017
vesicle mediated transport GO:0016192 381 0.017
localization of cell GO:0051674 257 0.017
male gamete generation GO:0048232 201 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.017
regulation of neural precursor cell proliferation GO:2000177 35 0.016
rna localization GO:0006403 115 0.016
organic substance catabolic process GO:1901575 308 0.016
endocytosis GO:0006897 310 0.016
camera type eye morphogenesis GO:0048593 2 0.016
vitamin biosynthetic process GO:0009110 1 0.016
larval behavior GO:0030537 42 0.016
outflow tract morphogenesis GO:0003151 4 0.016
malpighian tubule morphogenesis GO:0007443 44 0.016
cellular catabolic process GO:0044248 372 0.015
response to organophosphorus GO:0046683 2 0.015
cellular protein modification process GO:0006464 438 0.015
stem cell development GO:0048864 79 0.015
mating behavior GO:0007617 106 0.015
cell division GO:0051301 248 0.015
head development GO:0060322 135 0.015
response to extracellular stimulus GO:0009991 116 0.015
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.015
sensory perception of smell GO:0007608 80 0.015
central nervous system development GO:0007417 201 0.015
macromolecular complex assembly GO:0065003 256 0.015
embryonic morphogenesis GO:0048598 206 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
Human
cell proliferation GO:0008283 299 0.014
response to oxygen containing compound GO:1901700 200 0.014
kidney development GO:0001822 3 0.014
response to endogenous stimulus GO:0009719 119 0.014
Rat
regulation of cellular protein metabolic process GO:0032268 243 0.014
apoptotic process GO:0006915 159 0.014
ion transmembrane transport GO:0034220 122 0.014
regulation of protein metabolic process GO:0051246 256 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.014
neural retina development GO:0003407 4 0.014
fat soluble vitamin metabolic process GO:0006775 1 0.014
regulation of apoptotic process GO:0042981 130 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of cellular component size GO:0032535 98 0.013
formation of anatomical boundary GO:0048859 37 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
regulation of neuroblast proliferation GO:1902692 34 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
negative regulation of cell death GO:0060548 81 0.013
peptide biosynthetic process GO:0043043 42 0.013
response to external biotic stimulus GO:0043207 293 0.013
golgi organization GO:0007030 66 0.013
feeding behavior GO:0007631 50 0.013
gland development GO:0048732 191 0.013
regulation of molecular function GO:0065009 217 0.013
oocyte maturation GO:0001556 3 0.013
mesenchymal cell development GO:0014031 1 0.013
gland morphogenesis GO:0022612 145 0.013
polyol biosynthetic process GO:0046173 3 0.013
pole plasm oskar mrna localization GO:0045451 46 0.013
organophosphate metabolic process GO:0019637 195 0.012
cytoplasm organization GO:0007028 64 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
chromatin silencing GO:0006342 76 0.012
anterior posterior axis specification GO:0009948 109 0.012
nucleotide metabolic process GO:0009117 161 0.012
regulation of antimicrobial peptide production GO:0002784 44 0.012
cellular amide metabolic process GO:0043603 80 0.012
response to lipopolysaccharide GO:0032496 4 0.012
histolysis GO:0007559 102 0.012
sex differentiation GO:0007548 81 0.012
Rat
positive regulation of signaling GO:0023056 243 0.012
Rat
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
positive regulation of cell migration GO:0030335 2 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
muscle organ development GO:0007517 127 0.012
aggressive behavior GO:0002118 63 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
positive regulation of developmental process GO:0051094 143 0.012
Rat
gliogenesis GO:0042063 80 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
regulation of catalytic activity GO:0050790 185 0.012
regulation of gene silencing GO:0060968 63 0.012
dna conformation change GO:0071103 105 0.012
inorganic cation transmembrane transport GO:0098662 61 0.012
single organism behavior GO:0044708 391 0.012
response to other organism GO:0051707 293 0.012
sensory perception of pain GO:0019233 4 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
compound eye morphogenesis GO:0001745 249 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
phagocytosis GO:0006909 215 0.011
mesodermal cell fate specification GO:0007501 2 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
wnt signaling pathway GO:0016055 98 0.011
regulation of multi organism process GO:0043900 131 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
intracellular mrna localization GO:0008298 66 0.011
endomembrane system organization GO:0010256 119 0.011
convergent extension GO:0060026 2 0.011
nephron development GO:0072006 3 0.011
eye morphogenesis GO:0048592 260 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
cell fate determination GO:0001709 91 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
chromatin organization GO:0006325 207 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
positive regulation of cell communication GO:0010647 250 0.011
Rat
mitotic nuclear division GO:0007067 213 0.011
sensory perception of mechanical stimulus GO:0050954 72 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
regulation of cellular component movement GO:0051270 42 0.011
establishment of localization in cell GO:0051649 402 0.011
Rat
locomotory behavior GO:0007626 176 0.011
ion homeostasis GO:0050801 55 0.011
rhythmic process GO:0048511 106 0.011
Rat
tripartite regional subdivision GO:0007351 103 0.010
rna processing GO:0006396 147 0.010
regulation of reproductive process GO:2000241 54 0.010
Rat
determination of adult lifespan GO:0008340 137 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
fat soluble vitamin biosynthetic process GO:0042362 1 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
maintenance of location GO:0051235 73 0.010
imaginal disc pattern formation GO:0007447 91 0.010
cellular response to organic substance GO:0071310 132 0.010
Rat
digestive tract development GO:0048565 149 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
phosphorylation GO:0016310 294 0.010
stem cell proliferation GO:0072089 88 0.010
negative regulation of cell development GO:0010721 62 0.010

RunxA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
Human
disease of metabolism DOID:0014667 0 0.013
nervous system disease DOID:863 0 0.011
inherited metabolic disorder DOID:655 0 0.011
cardiovascular system disease DOID:1287 0 0.011