Drosophila melanogaster

45 known processes

Gem2 (Dmel_CG10419)

Gemin2

(Aliases: CG10419,Dmel\CG10419)

Gem2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell proliferation GO:0072089 88 0.274
nuclear division GO:0000280 332 0.243
asymmetric neuroblast division GO:0055059 33 0.230
stem cell division GO:0017145 69 0.214
organelle fission GO:0048285 340 0.195
neuroblast division GO:0055057 35 0.162
somatic stem cell division GO:0048103 37 0.153
neuroblast proliferation GO:0007405 74 0.138
neuronal stem cell division GO:0036445 35 0.137
asymmetric stem cell division GO:0098722 49 0.127
neural precursor cell proliferation GO:0061351 75 0.108
mitotic nuclear division GO:0007067 213 0.106
establishment or maintenance of cell polarity GO:0007163 167 0.105
spindle organization GO:0007051 253 0.087
single organism behavior GO:0044708 391 0.083
cellular catabolic process GO:0044248 372 0.077
phosphorylation GO:0016310 294 0.072
regulation of cell cycle process GO:0010564 181 0.072
negative regulation of signal transduction GO:0009968 206 0.072
small gtpase mediated signal transduction GO:0007264 88 0.071
regulation of mitotic cell cycle GO:0007346 190 0.068
dna metabolic process GO:0006259 227 0.067
cellular response to dna damage stimulus GO:0006974 223 0.064
mitotic spindle organization GO:0007052 220 0.059
macromolecule catabolic process GO:0009057 161 0.057
centrosome cycle GO:0007098 137 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.051
macromolecular complex assembly GO:0065003 256 0.050
chromatin organization GO:0006325 207 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.046
negative regulation of response to stimulus GO:0048585 258 0.046
chromosome organization GO:0051276 360 0.046
negative regulation of cell cycle phase transition GO:1901988 103 0.045
intracellular transport GO:0046907 228 0.043
sister chromatid segregation GO:0000819 92 0.042
intracellular signal transduction GO:0035556 300 0.042
cell division GO:0051301 248 0.040
regulation of immune system process GO:0002682 176 0.040
innate immune response GO:0045087 144 0.040
regulation of phosphate metabolic process GO:0019220 210 0.040
regulation of multicellular organismal development GO:2000026 414 0.039
open tracheal system development GO:0007424 204 0.039
respiratory system development GO:0060541 213 0.039
ras protein signal transduction GO:0007265 88 0.039
mitotic g2 dna damage checkpoint GO:0007095 69 0.039
response to wounding GO:0009611 94 0.036
central nervous system development GO:0007417 201 0.035
regulation of mitotic cell cycle phase transition GO:1901990 130 0.035
negative regulation of mitotic cell cycle GO:0045930 109 0.035
regulation of protein metabolic process GO:0051246 256 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.034
organic substance transport GO:0071702 257 0.033
compound eye photoreceptor cell differentiation GO:0001751 140 0.033
chromosome segregation GO:0007059 157 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
chromosome separation GO:0051304 42 0.030
protein localization GO:0008104 284 0.030
regulation of phosphorylation GO:0042325 147 0.030
regulation of cell cycle phase transition GO:1901987 130 0.030
regulation of cell cycle GO:0051726 291 0.030
organic substance catabolic process GO:1901575 308 0.029
locomotory behavior GO:0007626 176 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
muscle structure development GO:0061061 224 0.028
mitotic cell cycle phase transition GO:0044772 138 0.028
histone modification GO:0016570 106 0.027
negative regulation of cell cycle process GO:0010948 109 0.026
mitotic sister chromatid segregation GO:0000070 87 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
regulation of nervous system development GO:0051960 248 0.026
regulation of protein catabolic process GO:0042176 55 0.026
negative regulation of signaling GO:0023057 219 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.025
tracheal outgrowth open tracheal system GO:0007426 18 0.025
modification dependent macromolecule catabolic process GO:0043632 79 0.025
regulation of mitosis GO:0007088 56 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
regulation of intracellular signal transduction GO:1902531 236 0.023
striated muscle myosin thick filament assembly GO:0071688 3 0.023
vesicle mediated transport GO:0016192 381 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.023
protein dna complex assembly GO:0065004 63 0.023
regulation of organelle organization GO:0033043 196 0.023
spindle assembly involved in mitosis GO:0090307 50 0.022
cellular protein localization GO:0034613 160 0.022
catabolic process GO:0009056 409 0.022
protein complex assembly GO:0006461 200 0.022
regulation of catabolic process GO:0009894 170 0.022
protein dna complex subunit organization GO:0071824 86 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
regulation of chromosome organization GO:0033044 64 0.021
mrna metabolic process GO:0016071 124 0.021
synaptic transmission GO:0007268 288 0.020
negative regulation of gene expression GO:0010629 387 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
centrosome duplication GO:0051298 121 0.020
regulation of mapk cascade GO:0043408 92 0.020
single organism intracellular transport GO:1902582 207 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
reproductive behavior GO:0019098 122 0.020
meiotic dna double strand break formation GO:0042138 1 0.019
body morphogenesis GO:0010171 2 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
regulation of ras protein signal transduction GO:0046578 93 0.019
mapk cascade GO:0000165 107 0.019
cell proliferation GO:0008283 299 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.019
regulation of cell differentiation GO:0045595 302 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
cytoplasmic transport GO:0016482 130 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
compound eye morphogenesis GO:0001745 249 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.018
aging GO:0007568 143 0.018
regulation of cell development GO:0060284 215 0.018
appendage morphogenesis GO:0035107 397 0.018
regulation of response to wounding GO:1903034 19 0.018
chromatin modification GO:0016568 147 0.018
mitotic sister chromatid separation GO:0051306 30 0.018
endocytosis GO:0006897 310 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
positive regulation of gene expression GO:0010628 290 0.017
mitotic dna damage checkpoint GO:0044773 74 0.017
blastoderm segmentation GO:0007350 159 0.017
negative regulation of cell communication GO:0010648 223 0.017
regulation of proteolysis GO:0030162 87 0.017
microtubule organizing center organization GO:0031023 168 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.016
immune response GO:0006955 246 0.016
protein catabolic process GO:0030163 101 0.016
positive regulation of catabolic process GO:0009896 105 0.016
appendage development GO:0048736 401 0.016
protein complex biogenesis GO:0070271 201 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
wound healing GO:0042060 75 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
organelle assembly GO:0070925 198 0.015
meiotic cell cycle process GO:1903046 132 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
myofibril assembly GO:0030239 36 0.015
protein transport GO:0015031 155 0.015
actomyosin structure organization GO:0031032 56 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
response to ketone GO:1901654 34 0.015
larval development GO:0002164 104 0.015
protein modification process GO:0036211 438 0.015
mitotic g2 m transition checkpoint GO:0044818 70 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
positive regulation of rna metabolic process GO:0051254 271 0.014
negative regulation of ras protein signal transduction GO:0046580 13 0.014
positive regulation of cell communication GO:0010647 250 0.014
telencephalon development GO:0021537 2 0.014
muscle cell development GO:0055001 50 0.014
negative regulation of intracellular signal transduction GO:1902532 57 0.014
single organism cellular localization GO:1902580 180 0.014
compound eye development GO:0048749 307 0.014
regulation of nuclear division GO:0051783 58 0.014
cell cycle checkpoint GO:0000075 95 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.014
regulation of proteasomal protein catabolic process GO:0061136 39 0.014
dna dependent dna replication GO:0006261 17 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
striated muscle cell development GO:0055002 50 0.014
epithelial cell development GO:0002064 274 0.014
spinal cord development GO:0021510 1 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
covalent chromatin modification GO:0016569 106 0.014
regionalization GO:0003002 416 0.014
establishment of localization in cell GO:0051649 402 0.014
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
regulation of response to stress GO:0080134 200 0.013
regulation of neurogenesis GO:0050767 158 0.013
regulation of molecular function GO:0065009 217 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
determination of adult lifespan GO:0008340 137 0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
ovarian follicle cell development GO:0030707 248 0.013
negative regulation of cell cycle GO:0045786 116 0.013
positive regulation of signal transduction GO:0009967 223 0.013
larval behavior GO:0030537 42 0.013
regulation of cell division GO:0051302 72 0.013
regulation of erk1 and erk2 cascade GO:0070372 39 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
ribonucleoprotein complex biogenesis GO:0022613 31 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
forebrain development GO:0030900 2 0.012
actin cytoskeleton organization GO:0030036 206 0.012
regulation of mitotic sister chromatid segregation GO:0033047 28 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
phagocytosis GO:0006909 215 0.012
response to ecdysone GO:0035075 34 0.012
eye development GO:0001654 323 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
rna interference GO:0016246 27 0.011
positive regulation of cell cycle GO:0045787 43 0.011
growth GO:0040007 359 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
response to abiotic stimulus GO:0009628 341 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
chromatin remodeling GO:0006338 72 0.011
erk1 and erk2 cascade GO:0070371 39 0.011
meiotic nuclear division GO:0007126 151 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
dna repair GO:0006281 54 0.011
proteolysis GO:0006508 192 0.011
membrane organization GO:0061024 112 0.011
embryonic pattern specification GO:0009880 174 0.011
lateral inhibition GO:0046331 206 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
positive regulation of signaling GO:0023056 243 0.011
regulation of transport GO:0051049 181 0.011
dendrite development GO:0016358 204 0.011
protein processing GO:0016485 68 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
dna damage checkpoint GO:0000077 78 0.011
asymmetric protein localization GO:0008105 33 0.011
defense response GO:0006952 300 0.011
negative regulation of developmental process GO:0051093 201 0.011
synapse organization GO:0050808 196 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
immune system process GO:0002376 347 0.010
dna integrity checkpoint GO:0031570 81 0.010
cellular macromolecule localization GO:0070727 220 0.010
centrosome organization GO:0051297 163 0.010
brain development GO:0007420 120 0.010
response to alcohol GO:0097305 95 0.010
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
tube development GO:0035295 244 0.010

Gem2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027