Drosophila melanogaster

67 known processes

HLHm5 (Dmel_CG6096)

E(spl) region transcript m5

(Aliases: E(spl)-m5,Dmel\CG6096,E(spl)m5,HLH-m5,CG6096,m5,E(spl) transcription unit m5,bHLHb36,E(spl)M5)

HLHm5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ precursor cell fate determination GO:0016360 19 1.000
Fly
cell fate determination involved in pattern specification GO:0060582 19 0.999
Fly
formation of organ boundary GO:0010160 30 0.997
Fly
sensory organ boundary specification GO:0008052 22 0.997
Fly
cell fate determination GO:0001709 91 0.990
Mouse Fly
neuron fate determination GO:0048664 1 0.979
Mouse
organ formation GO:0048645 39 0.974
Fly
cell fate commitment involved in pattern specification GO:0060581 31 0.947
Fly
positive regulation of bmp signaling pathway GO:0030513 5 0.928
Mouse
r1 r6 cell differentiation GO:0048052 4 0.928
Fly
r7 cell differentiation GO:0045466 43 0.904
Fly
compound eye photoreceptor cell differentiation GO:0001751 140 0.898
Fly
cell maturation GO:0048469 144 0.898
Mouse
stem cell maintenance GO:0019827 67 0.894
Human Mouse Rat
nuclear division GO:0000280 332 0.875
Fly
morphogenesis of an epithelium GO:0002009 276 0.866
Mouse
regulation of neuroblast proliferation GO:1902692 34 0.857
Fly
formation of anatomical boundary GO:0048859 37 0.849
Fly
cell fate specification GO:0001708 71 0.845
Worm
malpighian tubule morphogenesis GO:0007443 44 0.838
regionalization GO:0003002 416 0.838
Zebrafish Mouse Worm Fly
tyrosine phosphorylation of stat protein GO:0007260 1 0.834
Mouse
nerve development GO:0021675 6 0.833
Mouse
sex determination GO:0007530 18 0.833
Fly
eye photoreceptor cell differentiation GO:0001754 145 0.812
Fly
mitotic nuclear division GO:0007067 213 0.802
Fly
organelle fission GO:0048285 340 0.802
Fly
regulation of cell development GO:0060284 215 0.772
Zebrafish Mouse Rat Fly
notch signaling pathway GO:0007219 120 0.761
Human Zebrafish Mouse Fly
negative regulation of transcription dna templated GO:0045892 237 0.759
telencephalon development GO:0021537 2 0.748
Mouse
axon ensheathment in central nervous system GO:0032291 3 0.747
Mouse
tissue morphogenesis GO:0048729 297 0.746
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.741
glial cell fate commitment GO:0021781 3 0.739
Mouse
brain development GO:0007420 120 0.735
Zebrafish Mouse Rat Fly
glial cell differentiation GO:0010001 35 0.723
Mouse Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.711
forebrain development GO:0030900 2 0.709
Mouse Rat
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.695
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.674
negative regulation of cellular metabolic process GO:0031324 382 0.665
nephron tubule formation GO:0072079 3 0.661
Mouse
gland morphogenesis GO:0022612 145 0.653
Fly
eye morphogenesis GO:0048592 260 0.648
Fly
segment specification GO:0007379 33 0.648
Zebrafish Mouse
somatic sex determination GO:0018993 2 0.642
Fly
tube development GO:0035295 244 0.641
Zebrafish Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.634
Mouse
locomotory behavior GO:0007626 176 0.632
Fly
regulation of nervous system development GO:0051960 248 0.631
Zebrafish Mouse Rat Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.611
salivary gland development GO:0007431 162 0.608
Fly
negative regulation of gene expression GO:0010629 387 0.608
positive regulation of rna metabolic process GO:0051254 271 0.600
Mouse
dendrite development GO:0016358 204 0.588
Fly
regulation of cell cycle process GO:0010564 181 0.587
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.574
regulation of cell morphogenesis GO:0022604 163 0.571
regulation of notch signaling pathway GO:0008593 100 0.560
Mouse
epithelial cell differentiation GO:0030855 322 0.559
Mouse Worm
head development GO:0060322 135 0.559
Zebrafish Mouse Rat Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.557
gliogenesis GO:0042063 80 0.549
Zebrafish Mouse Rat
dendrite morphogenesis GO:0048813 199 0.548
Fly
regulation of mitosis GO:0007088 56 0.544
Fly
sensory organ morphogenesis GO:0090596 260 0.542
Fly
cell division GO:0051301 248 0.538
Fly
photoreceptor cell differentiation GO:0046530 170 0.538
Fly
renal tubule development GO:0061326 64 0.528
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.526
regulation of glial cell differentiation GO:0045685 1 0.526
Mouse
regulation of nuclear division GO:0051783 58 0.520
Fly
axonogenesis GO:0007409 290 0.514
Zebrafish
hindbrain development GO:0030902 2 0.512
Mouse
neuronal stem cell maintenance GO:0097150 4 0.511
Human Mouse Rat
regulation of mitotic cell cycle GO:0007346 190 0.506
Fly
neural precursor cell proliferation GO:0061351 75 0.494
Fly
eye development GO:0001654 323 0.493
Zebrafish Mouse Fly
stem cell fate commitment GO:0048865 25 0.492
hindgut morphogenesis GO:0007442 58 0.490
neuroblast proliferation GO:0007405 74 0.485
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.483
positive regulation of cell cycle GO:0045787 43 0.478
Zebrafish Fly
sex determination establishment of x a ratio GO:0007540 1 0.466
Fly
hair cell differentiation GO:0035315 47 0.463
Mouse
regulation of bmp signaling pathway GO:0030510 23 0.458
Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.454
urogenital system development GO:0001655 72 0.449
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.446
negative regulation of notch signaling pathway GO:0045746 41 0.446
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.443
Rat
nephron epithelium morphogenesis GO:0072088 3 0.439
Mouse
neuroblast fate specification GO:0014018 2 0.436
positive regulation of developmental process GO:0051094 143 0.433
Fly
renal system development GO:0072001 72 0.433
Mouse
bolwig s organ development GO:0055034 8 0.430
camera type eye development GO:0043010 4 0.425
Mouse
central nervous system development GO:0007417 201 0.418
Zebrafish Mouse Rat Fly
dosage compensation GO:0007549 16 0.416
Fly
stem cell proliferation GO:0072089 88 0.414
Fly
regulation of timing of cell differentiation GO:0048505 1 0.410
Mouse
regulation of cell division GO:0051302 72 0.406
Fly
negative regulation of stem cell differentiation GO:2000737 8 0.402
Human
smoothened signaling pathway GO:0007224 49 0.401
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.399
Mouse
regulation of neuron differentiation GO:0045664 103 0.395
Mouse Rat
eye photoreceptor cell fate commitment GO:0042706 37 0.394
positive regulation of nervous system development GO:0051962 69 0.393
Fly
positive regulation of mitotic cell cycle GO:0045931 34 0.393
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.388
Mouse
glial cell development GO:0021782 27 0.386
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.384
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.383
Mouse
tube morphogenesis GO:0035239 191 0.382
Mouse Fly
compound eye photoreceptor fate commitment GO:0001752 36 0.378
epidermal cell differentiation GO:0009913 51 0.371
Mouse Worm
negative regulation of nervous system development GO:0051961 92 0.371
Zebrafish Mouse Rat
regulation of cell differentiation GO:0045595 302 0.369
Human Zebrafish Mouse Rat Fly
developmental maturation GO:0021700 172 0.367
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.364
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.350
Mouse
salivary gland morphogenesis GO:0007435 145 0.346
Fly
neuron projection guidance GO:0097485 241 0.344
positive regulation of rna biosynthetic process GO:1902680 266 0.338
Mouse
regulation of response to stress GO:0080134 200 0.338
Fly
regulation of stem cell proliferation GO:0072091 40 0.335
Fly
stem cell fate specification GO:0048866 2 0.335
nephron tubule morphogenesis GO:0072078 3 0.330
Mouse
positive regulation of gene expression GO:0010628 290 0.326
Mouse
regulation of neurogenesis GO:0050767 158 0.324
Zebrafish Mouse Rat Fly
neurological system process GO:0050877 358 0.324
Mouse Fly
kidney epithelium development GO:0072073 3 0.322
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.319
Mouse
negative regulation of cell development GO:0010721 62 0.317
Zebrafish Mouse Rat
nephron tubule development GO:0072080 3 0.316
Mouse
larval behavior GO:0030537 42 0.316
Fly
protein complex assembly GO:0006461 200 0.312
Mouse
cell motility GO:0048870 251 0.312
cell proliferation GO:0008283 299 0.307
Human Fly
regulation of cellular amine metabolic process GO:0033238 3 0.305
cellular response to dna damage stimulus GO:0006974 223 0.301
Fly
axon development GO:0061564 297 0.299
Zebrafish
embryonic morphogenesis GO:0048598 206 0.299
Zebrafish Mouse
mesoderm development GO:0007498 78 0.298
Fly
neuron fate specification GO:0048665 12 0.296
single organism behavior GO:0044708 391 0.295
Fly
gland development GO:0048732 191 0.295
Fly
neuron fate commitment GO:0048663 50 0.294
Mouse
positive regulation of cell development GO:0010720 61 0.293
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.292
negative regulation of developmental process GO:0051093 201 0.291
Human Zebrafish Mouse Rat
positive regulation of cell differentiation GO:0045597 64 0.291
Fly
immune response GO:0006955 246 0.288
startle response GO:0001964 16 0.287
Fly
immune system process GO:0002376 347 0.284
Rat
connective tissue development GO:0061448 3 0.283
Human Mouse
regulation of cell cycle GO:0051726 291 0.278
Zebrafish Fly
adult locomotory behavior GO:0008344 76 0.276
Fly
intracellular signal transduction GO:0035556 300 0.272
Mouse
positive regulation of cellular component organization GO:0051130 156 0.268
Fly
cellular amine metabolic process GO:0044106 12 0.260
dorsal ventral pattern formation GO:0009953 133 0.258
Fly
negative regulation of cell communication GO:0010648 223 0.255
regulation of neuron projection development GO:0010975 69 0.254
regulation of gliogenesis GO:0014013 11 0.248
Mouse
proximal distal pattern formation GO:0009954 15 0.247
Mouse
negative regulation of cell differentiation GO:0045596 143 0.245
Human Zebrafish Mouse Rat
positive regulation of neurogenesis GO:0050769 41 0.243
Fly
peptidyl tyrosine phosphorylation GO:0018108 24 0.227
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.226
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.225
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.221
positive regulation of macromolecule metabolic process GO:0010604 405 0.220
Zebrafish Mouse
digestive tract morphogenesis GO:0048546 127 0.215
positive regulation of multicellular organismal process GO:0051240 143 0.214
Fly
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.212
Zebrafish
digestive system development GO:0055123 149 0.211
axon guidance GO:0007411 233 0.211
response to other organism GO:0051707 293 0.208
enzyme linked receptor protein signaling pathway GO:0007167 179 0.206
Mouse
negative regulation of signal transduction GO:0009968 206 0.206
protein complex biogenesis GO:0070271 201 0.205
Mouse
neuroepithelial cell differentiation GO:0060563 6 0.204
bmp signaling pathway GO:0030509 27 0.203
Mouse
cell migration GO:0016477 238 0.203
peripheral nervous system neuron differentiation GO:0048934 8 0.198
Zebrafish
adult behavior GO:0030534 137 0.197
Fly
epithelial tube morphogenesis GO:0060562 88 0.195
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.195
negative regulation of immune system process GO:0002683 50 0.190
Rat
response to external biotic stimulus GO:0043207 293 0.188
regulation of neural precursor cell proliferation GO:2000177 35 0.184
Fly
compound eye development GO:0048749 307 0.183
Fly
negative regulation of biosynthetic process GO:0009890 277 0.183
neuroblast differentiation GO:0014016 29 0.183
regulation of cellular amino acid metabolic process GO:0006521 0 0.181
negative regulation of multicellular organismal process GO:0051241 142 0.177
Zebrafish Mouse Rat
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.177
Mouse
positive regulation of cell cycle process GO:0090068 28 0.177
Fly
peptidyl amino acid modification GO:0018193 105 0.170
Mouse
embryonic organ development GO:0048568 50 0.165
Zebrafish
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.165
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.163
Mouse
macromolecular complex assembly GO:0065003 256 0.157
Mouse
regulation of stem cell differentiation GO:2000736 14 0.157
Human
exocrine system development GO:0035272 162 0.156
Fly
spinal cord development GO:0021510 1 0.156
regulation of immune system process GO:0002682 176 0.154
Rat
tube formation GO:0035148 21 0.153
Mouse
epithelial cell development GO:0002064 274 0.153
primary sex determination soma GO:0007539 2 0.150
Fly
reproductive behavior GO:0019098 122 0.148
regulation of cellular ketone metabolic process GO:0010565 3 0.147
positive regulation of neuron differentiation GO:0045666 26 0.147
negative regulation of gliogenesis GO:0014014 6 0.146
Mouse
regulation of membrane potential GO:0042391 35 0.145
Mouse
kidney development GO:0001822 3 0.144
Mouse
localization of cell GO:0051674 257 0.142
response to abiotic stimulus GO:0009628 341 0.141
Fly
cellular ketone metabolic process GO:0042180 24 0.137
positive regulation of cell proliferation GO:0008284 47 0.137
Human Fly
positive regulation of organelle organization GO:0010638 65 0.136
Fly
actomyosin structure organization GO:0031032 56 0.135
compound eye morphogenesis GO:0001745 249 0.135
Fly
epidermal growth factor receptor signaling pathway GO:0007173 58 0.134
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.133
Mouse
peptidyl tyrosine modification GO:0018212 24 0.131
Mouse
skin development GO:0043588 65 0.128
Mouse Worm
negative regulation of cellular biosynthetic process GO:0031327 277 0.127
carboxylic acid metabolic process GO:0019752 92 0.127
photoreceptor cell fate commitment GO:0046552 41 0.124
response to decreased oxygen levels GO:0036293 58 0.123
Fly
organic acid metabolic process GO:0006082 103 0.122
negative regulation of cell cycle GO:0045786 116 0.121
cellular amino acid metabolic process GO:0006520 61 0.119
peripheral nervous system development GO:0007422 52 0.118
Zebrafish
regulation of cell projection organization GO:0031344 92 0.118
positive regulation of cellular biosynthetic process GO:0031328 316 0.118
Mouse
regulation of cellular response to stress GO:0080135 89 0.118
Fly
larval locomotory behavior GO:0008345 27 0.117
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.117
Zebrafish Mouse
stem cell development GO:0048864 79 0.116
Human Mouse Rat
defense response GO:0006952 300 0.115
response to hypoxia GO:0001666 53 0.115
Fly
nephron epithelium development GO:0072009 3 0.114
Mouse
transmission of nerve impulse GO:0019226 12 0.113
Mouse
epidermis development GO:0008544 65 0.113
Mouse Worm
protein modification process GO:0036211 438 0.113
Zebrafish Mouse
oenocyte development GO:0007438 8 0.113
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.112
Mouse
neuron recognition GO:0008038 101 0.110
regulation of cell proliferation GO:0042127 163 0.109
Human Fly
jak stat cascade GO:0007259 49 0.109
Mouse
neuroblast fate commitment GO:0014017 19 0.108
regulation of protein serine threonine kinase activity GO:0071900 25 0.108
Zebrafish
multi multicellular organism process GO:0044706 123 0.106
anterior posterior pattern specification GO:0009952 136 0.105
Zebrafish Mouse Worm
chemotaxis GO:0006935 249 0.104
positive regulation of neural precursor cell proliferation GO:2000179 8 0.104
Fly
protein phosphorylation GO:0006468 169 0.104
Zebrafish Mouse
negative regulation of signaling GO:0023057 219 0.103
nephron morphogenesis GO:0072028 3 0.102
Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.102
kidney morphogenesis GO:0060993 3 0.101
Mouse
hematopoietic progenitor cell differentiation GO:0002244 1 0.101
Rat
negative regulation of neurogenesis GO:0050768 53 0.100
Zebrafish Mouse Rat
multi organism reproductive behavior GO:0044705 121 0.099
nephron development GO:0072006 3 0.098
Mouse
cell recognition GO:0008037 102 0.098
regulation of epithelial cell differentiation GO:0030856 4 0.097
response to bacterium GO:0009617 198 0.097
regulation of kinase activity GO:0043549 53 0.096
Zebrafish
regulation of multicellular organismal development GO:2000026 414 0.095
Zebrafish Mouse Rat Fly
negative regulation of response to stimulus GO:0048585 258 0.095
negative regulation of cell cycle process GO:0010948 109 0.095
axon extension involved in axon guidance GO:0048846 10 0.095
mating behavior GO:0007617 106 0.094
positive regulation of stem cell proliferation GO:2000648 8 0.092
Fly
humoral immune response GO:0006959 117 0.091
chaeta development GO:0022416 97 0.091
locomotor rhythm GO:0045475 56 0.089
renal tubule morphogenesis GO:0061333 44 0.089
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.088
Zebrafish
hemopoiesis GO:0030097 46 0.087
Rat
regulation of glial cell proliferation GO:0060251 11 0.087
spinal cord patterning GO:0021511 1 0.086
response to oxygen levels GO:0070482 59 0.086
Fly
establishment of tissue polarity GO:0007164 87 0.086
positive regulation of signal transduction GO:0009967 223 0.085
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.084
regulation of axon extension involved in axon guidance GO:0048841 4 0.083
regulation of protein metabolic process GO:0051246 256 0.083
Zebrafish Mouse
biological adhesion GO:0022610 138 0.083
Mouse
developmental cell growth GO:0048588 52 0.082
positive regulation of transcription dna templated GO:0045893 266 0.081
Mouse
negative regulation of glial cell proliferation GO:0060253 6 0.081
multicellular organismal signaling GO:0035637 12 0.080
Mouse
positive regulation of response to stimulus GO:0048584 323 0.080
Mouse
positive regulation of neuroblast proliferation GO:0002052 7 0.079
Fly
regulation of molecular function GO:0065009 217 0.079
Zebrafish
segmentation GO:0035282 207 0.078
Zebrafish Mouse
response to organic substance GO:0010033 284 0.076
regulation of organelle organization GO:0033043 196 0.076
Fly
stem cell differentiation GO:0048863 117 0.076
Human Mouse Rat
regulation of phosphate metabolic process GO:0019220 210 0.075
Zebrafish Mouse
regulation of intracellular signal transduction GO:1902531 236 0.075
Mouse
taxis GO:0042330 304 0.074
respiratory system development GO:0060541 213 0.074
Fly
bolwig s organ morphogenesis GO:0001746 8 0.074
regulation of programmed cell death GO:0043067 152 0.074
amine metabolic process GO:0009308 12 0.073
organonitrogen compound metabolic process GO:1901564 318 0.073
neuron projection extension GO:1990138 32 0.071
erbb signaling pathway GO:0038127 58 0.070
defense response to other organism GO:0098542 225 0.070
regulation of dendrite morphogenesis GO:0048814 28 0.070
cellular protein modification process GO:0006464 438 0.067
Zebrafish Mouse
aging GO:0007568 143 0.067
rhythmic process GO:0048511 106 0.067
Mouse
endoderm development GO:0007492 6 0.067
Zebrafish
positive regulation of cell division GO:0051781 16 0.066
Fly
regulation of protein phosphorylation GO:0001932 64 0.066
Zebrafish Mouse
regulation of protein kinase activity GO:0045859 51 0.065
Zebrafish
sensory perception of mechanical stimulus GO:0050954 72 0.065
positive regulation of notch signaling pathway GO:0045747 34 0.064
Mouse
central nervous system neuron development GO:0021954 8 0.064
medulla oblongata development GO:0021550 2 0.064
positive regulation of molecular function GO:0044093 136 0.063
Zebrafish
regulation of neuron death GO:1901214 26 0.063
epithelial cell proliferation GO:0050673 15 0.062
glandular epithelial cell differentiation GO:0002067 1 0.061
circadian rhythm GO:0007623 105 0.061
phosphorylation GO:0016310 294 0.060
Zebrafish Mouse
glial cell proliferation GO:0014009 13 0.060
embryonic epithelial tube formation GO:0001838 6 0.060
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.059
Zebrafish Mouse
small molecule metabolic process GO:0044281 305 0.058
negative regulation of mitotic cell cycle GO:0045930 109 0.058
developmental growth GO:0048589 280 0.058
gastrulation with mouth forming first GO:0001703 36 0.058
regulation of cellular component size GO:0032535 98 0.058
cell death GO:0008219 279 0.057
neuromuscular process GO:0050905 21 0.057
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.056
Mouse
negative regulation of programmed cell death GO:0043069 72 0.056
courtship behavior GO:0007619 68 0.055
hindgut development GO:0061525 58 0.055
response to biotic stimulus GO:0009607 294 0.054
ensheathment of neurons GO:0007272 10 0.054
Mouse
endocytosis GO:0006897 310 0.054
neuroblast fate determination GO:0007400 12 0.054
oxoacid metabolic process GO:0043436 103 0.054
appendage development GO:0048736 401 0.053
brain morphogenesis GO:0048854 16 0.052
Fly
negative regulation of cellular component organization GO:0051129 108 0.052
actin cytoskeleton organization GO:0030036 206 0.052
regulation of oviposition GO:0046662 14 0.051
regulation of axon extension GO:0030516 8 0.051
axon ensheathment GO:0008366 10 0.050
Mouse
imaginal disc pattern formation GO:0007447 91 0.048
Fly
neuron migration GO:0001764 5 0.048
rhythmic behavior GO:0007622 76 0.048
circadian behavior GO:0048512 76 0.048
cranial nerve development GO:0021545 1 0.047
Mouse
malpighian tubule tip cell differentiation GO:0061382 9 0.047
epithelial tube formation GO:0072175 7 0.046
Mouse
macromolecule catabolic process GO:0009057 161 0.046
action potential GO:0001508 13 0.046
Mouse
programmed cell death GO:0012501 257 0.046
regulation of axonogenesis GO:0050770 32 0.045
r8 cell fate commitment GO:0007460 6 0.044
male courtship behavior GO:0008049 63 0.044
imaginal disc derived appendage morphogenesis GO:0035114 395 0.044
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.044
Mouse
regulation of catalytic activity GO:0050790 185 0.042
Zebrafish
actin filament based process GO:0030029 220 0.042
neural retina development GO:0003407 4 0.042
stem cell fate determination GO:0048867 15 0.042
camera type eye morphogenesis GO:0048593 2 0.042
positive regulation of transferase activity GO:0051347 26 0.041
Zebrafish
male courtship behavior veined wing vibration GO:0016545 21 0.041
response to wounding GO:0009611 94 0.040
regulation of cell death GO:0010941 173 0.040
regulation of axon guidance GO:1902667 10 0.040
wing disc pattern formation GO:0035222 66 0.039
Fly
gastrulation involving germ band extension GO:0010004 36 0.039
positive regulation of intracellular signal transduction GO:1902533 116 0.039
Mouse
male courtship behavior veined wing generated song production GO:0045433 20 0.039
regulation of dendrite development GO:0050773 37 0.038
multi organism behavior GO:0051705 175 0.038
antimicrobial humoral response GO:0019730 99 0.038
gastrulation GO:0007369 70 0.037
positive regulation of signaling GO:0023056 243 0.037
Mouse
appendage morphogenesis GO:0035107 397 0.037
regulation of response to dna damage stimulus GO:2001020 23 0.037
Fly
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.036
Fly
regulation of immune response GO:0050776 118 0.036
neuronal action potential GO:0019228 10 0.036
Mouse
vesicle mediated transport GO:0016192 381 0.036
retina development in camera type eye GO:0060041 4 0.036
open tracheal system development GO:0007424 204 0.035
Fly
regulation of anatomical structure size GO:0090066 163 0.035
ovarian follicle cell development GO:0030707 248 0.035
positive regulation of catalytic activity GO:0043085 118 0.035
Zebrafish
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
Zebrafish Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.035
Mouse
peripheral nervous system neuron development GO:0048935 8 0.035
Zebrafish
cell adhesion GO:0007155 136 0.035
Mouse
embryonic organ morphogenesis GO:0048562 5 0.034
Zebrafish
positive regulation of protein kinase activity GO:0045860 25 0.033
Zebrafish
death GO:0016265 284 0.033
ectodermal placode development GO:0071696 4 0.033
regulation of behavior GO:0050795 75 0.033
immune system development GO:0002520 57 0.033
Rat
regulation of transferase activity GO:0051338 58 0.033
Zebrafish
regulation of reproductive process GO:2000241 54 0.032
spinal cord dorsal ventral patterning GO:0021513 1 0.032
regulation of protein modification process GO:0031399 112 0.031
Zebrafish Mouse
somatic stem cell maintenance GO:0035019 14 0.031
leg disc development GO:0035218 92 0.031
morphogenesis of a polarized epithelium GO:0001738 93 0.030
neuron apoptotic process GO:0051402 17 0.030
positive regulation of phosphorylation GO:0042327 87 0.030
Zebrafish Mouse
neuroblast division GO:0055057 35 0.030
positive regulation of protein metabolic process GO:0051247 128 0.029
Zebrafish Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
dna metabolic process GO:0006259 227 0.028
chaeta morphogenesis GO:0008407 42 0.028
regulation of localization GO:0032879 275 0.027
striated muscle cell development GO:0055002 50 0.027
positive regulation of cell communication GO:0010647 250 0.027
Mouse
muscle structure development GO:0061061 224 0.027
larval development GO:0002164 104 0.027
wing disc dorsal ventral pattern formation GO:0048190 47 0.026
Fly
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.026
muscle cell development GO:0055001 50 0.026
striated muscle cell differentiation GO:0051146 90 0.026
central nervous system neuron differentiation GO:0021953 8 0.026
Rat
negative regulation of cell proliferation GO:0008285 69 0.026
immune effector process GO:0002252 98 0.026
regulation of apoptotic process GO:0042981 130 0.026
ommatidial rotation GO:0016318 20 0.026
establishment of planar polarity GO:0001736 87 0.025
mesodermal cell fate commitment GO:0001710 7 0.024
regulation of humoral immune response GO:0002920 51 0.024
regulation of cell cycle phase transition GO:1901987 130 0.024
organic substance transport GO:0071702 257 0.024
muscle fiber development GO:0048747 12 0.024
organelle assembly GO:0070925 198 0.023
male courtship behavior veined wing extension GO:0048065 22 0.023
regulation of cellular component movement GO:0051270 42 0.023
wound healing GO:0042060 75 0.023
regulation of antimicrobial peptide production GO:0002784 44 0.023
sensory perception of sound GO:0007605 56 0.023
regulation of phosphorylation GO:0042325 147 0.022
Zebrafish Mouse
imaginal disc derived appendage development GO:0048737 399 0.022
phagocytosis GO:0006909 215 0.022
regulation of multi organism process GO:0043900 131 0.022
positive regulation of kinase activity GO:0033674 25 0.022
Zebrafish
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.022
positive regulation of phosphate metabolic process GO:0045937 139 0.021
Zebrafish Mouse
ventral furrow formation GO:0007370 17 0.021
r3 r4 cell differentiation GO:0048056 12 0.021
lateral inhibition GO:0046331 206 0.021
negative regulation of organelle organization GO:0010639 56 0.021
regulation of production of molecular mediator of immune response GO:0002700 44 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.021
positive regulation of protein phosphorylation GO:0001934 34 0.021
Zebrafish Mouse
response to endogenous stimulus GO:0009719 119 0.020
maintenance of location GO:0051235 73 0.020
muscle cell differentiation GO:0042692 103 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
response to hexose GO:0009746 3 0.020
response to axon injury GO:0048678 12 0.020
eye antennal disc morphogenesis GO:0007455 34 0.019
neuropeptide signaling pathway GO:0007218 45 0.019
regulation of developmental growth GO:0048638 174 0.019
stress activated mapk cascade GO:0051403 52 0.019
chorion containing eggshell formation GO:0007304 105 0.019
retina morphogenesis in camera type eye GO:0060042 2 0.019
epithelial cell migration GO:0010631 148 0.019
body morphogenesis GO:0010171 2 0.019
antimicrobial peptide production GO:0002775 46 0.019
regulation of cellular amide metabolic process GO:0034248 39 0.019
mesodermal cell differentiation GO:0048333 7 0.019
catabolic process GO:0009056 409 0.018
secretion GO:0046903 109 0.018
regeneration GO:0031099 16 0.018
cellular response to organic substance GO:0071310 132 0.017
vesicle organization GO:0016050 44 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017

HLHm5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.823
Human
bone disease DOID:0080001 0 0.823
Human
disease of anatomical entity DOID:7 0 0.823
Human
dysostosis DOID:1934 0 0.823
Human
musculoskeletal system disease DOID:17 0 0.823
Human
connective tissue disease DOID:65 0 0.823
Human
spondylocostal dysostosis DOID:0050568 0 0.441
Human