Drosophila melanogaster

99 known processes

BHD (Dmel_CG8616)

Birt-Hogg-Dube homolog

(Aliases: Dmel\CG8616,CG8616,DBHD)

BHD biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.202
regionalization GO:0003002 416 0.195
imaginal disc derived appendage development GO:0048737 399 0.195
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.180
negative regulation of gene expression GO:0010629 387 0.162
regulation of behavior GO:0050795 75 0.147
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.133
post embryonic appendage morphogenesis GO:0035120 385 0.129
regulation of cell proliferation GO:0042127 163 0.127
response to oxygen containing compound GO:1901700 200 0.122
wing disc morphogenesis GO:0007472 344 0.122
cell proliferation GO:0008283 299 0.117
organelle fission GO:0048285 340 0.111
oocyte differentiation GO:0009994 145 0.110
imaginal disc derived wing morphogenesis GO:0007476 337 0.099
appendage development GO:0048736 401 0.098
positive regulation of transcription dna templated GO:0045893 266 0.098
compound eye development GO:0048749 307 0.098
embryonic morphogenesis GO:0048598 206 0.095
response to organic substance GO:0010033 284 0.094
tissue morphogenesis GO:0048729 297 0.093
negative regulation of transcription dna templated GO:0045892 237 0.090
negative regulation of cellular metabolic process GO:0031324 382 0.087
male gamete generation GO:0048232 201 0.083
negative regulation of nucleic acid templated transcription GO:1903507 240 0.083
meiotic cell cycle GO:0051321 171 0.082
regulation of anatomical structure size GO:0090066 163 0.082
negative regulation of response to stimulus GO:0048585 258 0.076
insulin receptor signaling pathway GO:0008286 25 0.072
cell maturation GO:0048469 144 0.071
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.070
nucleobase containing small molecule metabolic process GO:0055086 174 0.068
positive regulation of cellular biosynthetic process GO:0031328 316 0.067
developmental maturation GO:0021700 172 0.067
cellular lipid metabolic process GO:0044255 83 0.067
regulation of organ growth GO:0046620 42 0.066
morphogenesis of an epithelium GO:0002009 276 0.066
defense response to other organism GO:0098542 225 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.062
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.062
stem cell differentiation GO:0048863 117 0.061
sensory organ morphogenesis GO:0090596 260 0.061
negative regulation of biosynthetic process GO:0009890 277 0.059
enzyme linked receptor protein signaling pathway GO:0007167 179 0.058
response to bacterium GO:0009617 198 0.057
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.057
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.055
cellular response to oxygen containing compound GO:1901701 79 0.055
eye morphogenesis GO:0048592 260 0.055
cellular protein modification process GO:0006464 438 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.055
cellular response to insulin stimulus GO:0032869 28 0.054
appendage morphogenesis GO:0035107 397 0.054
cellular response to chemical stimulus GO:0070887 199 0.054
vesicle mediated transport GO:0016192 381 0.054
spermatid differentiation GO:0048515 114 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.053
negative regulation of cell communication GO:0010648 223 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
cell growth GO:0016049 108 0.052
circadian behavior GO:0048512 76 0.051
spermatogenesis GO:0007283 200 0.051
response to biotic stimulus GO:0009607 294 0.051
growth GO:0040007 359 0.050
response to abiotic stimulus GO:0009628 341 0.049
stem cell maintenance GO:0019827 67 0.049
camera type eye development GO:0043010 4 0.049
rhythmic process GO:0048511 106 0.048
response to external biotic stimulus GO:0043207 293 0.048
positive regulation of rna metabolic process GO:0051254 271 0.047
multi multicellular organism process GO:0044706 123 0.047
cell death GO:0008219 279 0.047
immune response GO:0006955 246 0.045
localization of cell GO:0051674 257 0.045
response to insulin GO:0032868 29 0.045
cellular response to organic substance GO:0071310 132 0.044
locomotor rhythm GO:0045475 56 0.044
immune system process GO:0002376 347 0.044
germ line stem cell maintenance GO:0030718 50 0.043
negative regulation of signal transduction GO:0009968 206 0.043
cellular response to peptide hormone stimulus GO:0071375 28 0.043
cellular response to nitrogen compound GO:1901699 51 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
regulation of cell development GO:0060284 215 0.042
regulation of cellular component size GO:0032535 98 0.041
regulation of multi organism process GO:0043900 131 0.041
lipid metabolic process GO:0006629 121 0.041
cellular response to peptide GO:1901653 28 0.041
negative regulation of developmental process GO:0051093 201 0.039
regulation of response to stress GO:0080134 200 0.039
determination of adult lifespan GO:0008340 137 0.039
multi organism behavior GO:0051705 175 0.039
aging GO:0007568 143 0.038
regulation of protein metabolic process GO:0051246 256 0.038
meiotic nuclear division GO:0007126 151 0.038
catabolic process GO:0009056 409 0.037
salivary gland development GO:0007431 162 0.037
germarium derived egg chamber formation GO:0007293 101 0.036
skin development GO:0043588 65 0.036
protein modification process GO:0036211 438 0.036
response to other organism GO:0051707 293 0.035
transcription from rna polymerase ii promoter GO:0006366 368 0.035
organic substance catabolic process GO:1901575 308 0.035
digestive tract development GO:0048565 149 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
larval feeding behavior GO:0030536 15 0.034
oocyte development GO:0048599 124 0.033
negative regulation of cell differentiation GO:0045596 143 0.032
ameboidal type cell migration GO:0001667 151 0.032
axis specification GO:0009798 167 0.032
regulation of cell differentiation GO:0045595 302 0.032
positive regulation of developmental process GO:0051094 143 0.031
tube morphogenesis GO:0035239 191 0.031
negative regulation of signaling GO:0023057 219 0.031
death GO:0016265 284 0.031
multicellular organismal aging GO:0010259 140 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
chromatin modification GO:0016568 147 0.030
regulation of reproductive process GO:2000241 54 0.030
telencephalon development GO:0021537 2 0.030
regulation of organ morphogenesis GO:2000027 78 0.030
reproductive behavior GO:0019098 122 0.029
segmentation GO:0035282 207 0.029
response to peptide hormone GO:0043434 29 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
organophosphate metabolic process GO:0019637 195 0.029
larval behavior GO:0030537 42 0.028
multi organism reproductive behavior GO:0044705 121 0.028
eye photoreceptor cell differentiation GO:0001754 145 0.028
salivary gland morphogenesis GO:0007435 145 0.028
chemosensory behavior GO:0007635 106 0.028
developmental growth GO:0048589 280 0.027
apoptotic process GO:0006915 159 0.027
regulation of growth GO:0040008 233 0.027
oocyte axis specification GO:0007309 108 0.027
eye development GO:0001654 323 0.027
exocrine system development GO:0035272 162 0.026
response to alcohol GO:0097305 95 0.026
cellular response to endogenous stimulus GO:0071495 80 0.026
compound eye morphogenesis GO:0001745 249 0.025
cell migration GO:0016477 238 0.025
response to temperature stimulus GO:0009266 106 0.025
adult behavior GO:0030534 137 0.025
eye antennal disc development GO:0035214 60 0.025
small molecule metabolic process GO:0044281 305 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
response to lipopolysaccharide GO:0032496 4 0.025
regulation of rna splicing GO:0043484 69 0.024
defense response GO:0006952 300 0.024
maintenance of location GO:0051235 73 0.024
innate immune response GO:0045087 144 0.024
locomotory behavior GO:0007626 176 0.024
lipid homeostasis GO:0055088 33 0.024
positive regulation of gene expression GO:0010628 290 0.024
positive regulation of growth GO:0045927 75 0.023
imaginal disc derived wing vein specification GO:0007474 48 0.023
cellular ketone metabolic process GO:0042180 24 0.023
regulation of localization GO:0032879 275 0.023
response to organonitrogen compound GO:0010243 75 0.022
regulation of epithelial cell differentiation GO:0030856 4 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
cellular response to organonitrogen compound GO:0071417 36 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
protein localization GO:0008104 284 0.022
establishment of localization in cell GO:0051649 402 0.022
organic acid metabolic process GO:0006082 103 0.021
detection of stimulus GO:0051606 156 0.021
cellular macromolecule localization GO:0070727 220 0.021
programmed cell death GO:0012501 257 0.021
epithelial cell differentiation GO:0030855 322 0.021
regulation of developmental growth GO:0048638 174 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
circadian rhythm GO:0007623 105 0.021
response to endogenous stimulus GO:0009719 119 0.021
feeding behavior GO:0007631 50 0.020
oocyte construction GO:0007308 112 0.020
cellularization GO:0007349 90 0.020
multicellular organismal reproductive behavior GO:0033057 110 0.020
rhythmic behavior GO:0007622 76 0.020
negative regulation of cellular component organization GO:0051129 108 0.019
macromolecular complex assembly GO:0065003 256 0.019
peptidyl amino acid modification GO:0018193 105 0.019
macromolecule catabolic process GO:0009057 161 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
protein ubiquitination GO:0016567 70 0.019
detection of abiotic stimulus GO:0009582 66 0.019
organ growth GO:0035265 56 0.019
positive regulation of cell communication GO:0010647 250 0.019
positive regulation of cell motility GO:2000147 3 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
neurological system process GO:0050877 358 0.019
regulation of synapse structure and activity GO:0050803 128 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
response to nitrogen compound GO:1901698 90 0.018
single organism catabolic process GO:0044712 228 0.018
gland morphogenesis GO:0022612 145 0.018
chromosome organization GO:0051276 360 0.018
retina development in camera type eye GO:0060041 4 0.017
regulation of mrna processing GO:0050684 71 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
nuclear division GO:0000280 332 0.017
epidermis development GO:0008544 65 0.017
regulation of cell size GO:0008361 63 0.017
regulation of mapk cascade GO:0043408 92 0.017
regulation of nuclear division GO:0051783 58 0.017
cellular protein complex assembly GO:0043623 71 0.017
olfactory behavior GO:0042048 97 0.017
regulation of organelle organization GO:0033043 196 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
regulation of catabolic process GO:0009894 170 0.016
dendrite morphogenesis GO:0048813 199 0.016
imaginal disc pattern formation GO:0007447 91 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
homeostatic process GO:0042592 199 0.016
intracellular signal transduction GO:0035556 300 0.016
stem cell development GO:0048864 79 0.016
positive regulation of signaling GO:0023056 243 0.016
anterior posterior axis specification GO:0009948 109 0.016
pole plasm assembly GO:0007315 61 0.016
transmembrane transport GO:0055085 139 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
response to heat GO:0009408 63 0.016
secondary metabolic process GO:0019748 75 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
phagocytosis GO:0006909 215 0.016
negative regulation of apoptotic process GO:0043066 63 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
kidney epithelium development GO:0072073 3 0.015
mrna metabolic process GO:0016071 124 0.015
positive regulation of signal transduction GO:0009967 223 0.015
tripartite regional subdivision GO:0007351 103 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
nucleotide metabolic process GO:0009117 161 0.015
response to nutrient levels GO:0031667 114 0.015
sensory perception GO:0007600 196 0.015
rna splicing GO:0008380 83 0.015
regulation of feeding behavior GO:0060259 16 0.015
positive regulation of developmental growth GO:0048639 62 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
ras protein signal transduction GO:0007265 88 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
camera type eye morphogenesis GO:0048593 2 0.015
nucleoside metabolic process GO:0009116 127 0.015
cellular protein localization GO:0034613 160 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
regulation of apoptotic process GO:0042981 130 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
regulation of cellular localization GO:0060341 136 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
leg disc morphogenesis GO:0007478 80 0.014
detection of external stimulus GO:0009581 66 0.014
humoral immune response GO:0006959 117 0.014
anterior posterior pattern specification GO:0009952 136 0.014
regulation of immune response GO:0050776 118 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
response to organic cyclic compound GO:0014070 89 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
aromatic compound catabolic process GO:0019439 166 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
developmental programmed cell death GO:0010623 138 0.014
negative regulation of cell development GO:0010721 62 0.014
response to hormone GO:0009725 45 0.013
antimicrobial humoral response GO:0019730 99 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
endosomal transport GO:0016197 44 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
female meiotic division GO:0007143 70 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
digestive system development GO:0055123 149 0.013
amine metabolic process GO:0009308 12 0.013
anatomical structure homeostasis GO:0060249 97 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
regulation of response to dna damage stimulus GO:2001020 23 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
response to radiation GO:0009314 155 0.013
vitamin biosynthetic process GO:0009110 1 0.013
organic substance transport GO:0071702 257 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
negative regulation of cell death GO:0060548 81 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
regulation of cell cycle GO:0051726 291 0.012
regulation of neural precursor cell proliferation GO:2000177 35 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
response to peptide GO:1901652 29 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
protein phosphorylation GO:0006468 169 0.012
endocytosis GO:0006897 310 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
rna processing GO:0006396 147 0.012
limb development GO:0060173 1 0.012
pigment metabolic process GO:0042440 84 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.012
chromatin organization GO:0006325 207 0.012
organophosphate catabolic process GO:0046434 112 0.012
dna damage checkpoint GO:0000077 78 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
male meiosis GO:0007140 52 0.012
intracellular transport GO:0046907 228 0.012
epithelial cell migration GO:0010631 148 0.012
negative regulation of organelle organization GO:0010639 56 0.012
cellular response to hormone stimulus GO:0032870 44 0.012
regulation of meiosis GO:0040020 3 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.012
mesenchymal cell development GO:0014031 1 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of cell death GO:0010941 173 0.012
histolysis GO:0007559 102 0.011
cell fate specification GO:0001708 71 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
cellular catabolic process GO:0044248 372 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
histone modification GO:0016570 106 0.011
carbohydrate utilization GO:0009758 1 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
nucleotide catabolic process GO:0009166 109 0.011
detection of light stimulus GO:0009583 58 0.011
kidney development GO:0001822 3 0.011
positive regulation of molecular function GO:0044093 136 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
gland development GO:0048732 191 0.011
adult locomotory behavior GO:0008344 76 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
phosphorylation GO:0016310 294 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
protein complex biogenesis GO:0070271 201 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
gene silencing GO:0016458 138 0.011
forebrain development GO:0030900 2 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
leg disc development GO:0035218 92 0.010
sperm individualization GO:0007291 48 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
anion homeostasis GO:0055081 3 0.010
behavioral response to pain GO:0048266 3 0.010
regulation of erbb signaling pathway GO:1901184 42 0.010
mating behavior GO:0007617 106 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
regulation of translation GO:0006417 56 0.010
dendrite development GO:0016358 204 0.010
regulation of immune system process GO:0002682 176 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
regulation of programmed cell death GO:0043067 152 0.010
single organism cellular localization GO:1902580 180 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010

BHD disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.011