Drosophila melanogaster

72 known processes

CSN6 (Dmel_CG6932)

COP9 complex homolog subunit 6

(Aliases: CG6932,Dmel\CG6932,Dch6,CH6)

CSN6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein deneddylation GO:0000338 8 0.579
cellular response to dna damage stimulus GO:0006974 223 0.507
mitotic g2 m transition checkpoint GO:0044818 70 0.504
protein modification by small protein removal GO:0070646 28 0.490
cell division GO:0051301 248 0.490
regulation of cell cycle phase transition GO:1901987 130 0.479
protein modification process GO:0036211 438 0.464
regulation of cell cycle GO:0051726 291 0.370
regulation of mitotic cell cycle phase transition GO:1901990 130 0.353
cell cycle phase transition GO:0044770 140 0.337
cellular protein modification process GO:0006464 438 0.320
regulation of cell cycle process GO:0010564 181 0.274
regulation of protein metabolic process GO:0051246 256 0.270
regulation of mitotic cell cycle GO:0007346 190 0.269
cell cycle checkpoint GO:0000075 95 0.268
covalent chromatin modification GO:0016569 106 0.265
protein modification by small protein conjugation or removal GO:0070647 106 0.249
mitotic dna integrity checkpoint GO:0044774 75 0.234
establishment of organelle localization GO:0051656 122 0.221
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.206
ubiquitin dependent protein catabolic process GO:0006511 78 0.171
mitotic cell cycle phase transition GO:0044772 138 0.165
cellular catabolic process GO:0044248 372 0.162
chromatin organization GO:0006325 207 0.160
negative regulation of gene expression GO:0010629 387 0.158
chromatin modification GO:0016568 147 0.154
negative regulation of mitotic cell cycle GO:0045930 109 0.146
positive regulation of transcription dna templated GO:0045893 266 0.141
histone exchange GO:0043486 21 0.139
mitotic cell cycle checkpoint GO:0007093 88 0.136
negative regulation of cell cycle phase transition GO:1901988 103 0.134
dna integrity checkpoint GO:0031570 81 0.129
mitotic g2 dna damage checkpoint GO:0007095 69 0.127
proteolysis GO:0006508 192 0.119
posttranscriptional regulation of gene expression GO:0010608 145 0.115
mitotic dna damage checkpoint GO:0044773 74 0.115
dna damage checkpoint GO:0000077 78 0.114
histone modification GO:0016570 106 0.104
g2 dna damage checkpoint GO:0031572 69 0.103
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.102
organic substance catabolic process GO:1901575 308 0.099
protein deubiquitination GO:0016579 17 0.087
modification dependent macromolecule catabolic process GO:0043632 79 0.085
peptidyl lysine modification GO:0018205 57 0.082
histone acetylation GO:0016573 38 0.081
catabolic process GO:0009056 409 0.081
regulation of cellular protein metabolic process GO:0032268 243 0.080
macromolecule catabolic process GO:0009057 161 0.075
protein catabolic process GO:0030163 101 0.072
lateral inhibition GO:0046331 206 0.072
cellular protein catabolic process GO:0044257 83 0.071
chromatin remodeling GO:0006338 72 0.069
positive regulation of macromolecule metabolic process GO:0010604 405 0.066
positive regulation of biosynthetic process GO:0009891 316 0.066
spermatid differentiation GO:0048515 114 0.064
chromatin assembly GO:0031497 48 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.064
establishment of localization in cell GO:0051649 402 0.063
regulation of molecular function GO:0065009 217 0.062
positive regulation of cellular biosynthetic process GO:0031328 316 0.062
regulation of cell death GO:0010941 173 0.060
modification dependent protein catabolic process GO:0019941 78 0.060
cytokinesis GO:0000910 90 0.060
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.059
chromosome organization GO:0051276 360 0.058
regulation of phosphate metabolic process GO:0019220 210 0.058
organonitrogen compound metabolic process GO:1901564 318 0.057
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.056
embryo development ending in birth or egg hatching GO:0009792 152 0.056
protein localization GO:0008104 284 0.056
negative regulation of signaling GO:0023057 219 0.055
negative regulation of cellular metabolic process GO:0031324 382 0.055
camera type eye development GO:0043010 4 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.054
wing disc morphogenesis GO:0007472 344 0.054
negative regulation of cell cycle process GO:0010948 109 0.053
intracellular transport GO:0046907 228 0.052
epithelial cell differentiation GO:0030855 322 0.050
organelle localization GO:0051640 148 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.046
internal protein amino acid acetylation GO:0006475 38 0.046
transcription from rna polymerase ii promoter GO:0006366 368 0.046
rna processing GO:0006396 147 0.045
negative regulation of rna metabolic process GO:0051253 251 0.044
regulation of proteolysis GO:0030162 87 0.044
positive regulation of cellular protein metabolic process GO:0032270 118 0.043
enzyme linked receptor protein signaling pathway GO:0007167 179 0.043
segmentation GO:0035282 207 0.042
vesicle mediated transport GO:0016192 381 0.042
regulation of programmed cell death GO:0043067 152 0.041
response to radiation GO:0009314 155 0.041
positive regulation of protein metabolic process GO:0051247 128 0.040
single organism cellular localization GO:1902580 180 0.040
cell projection assembly GO:0030031 94 0.039
negative regulation of transcription dna templated GO:0045892 237 0.039
axonogenesis GO:0007409 290 0.039
regulation of protein modification process GO:0031399 112 0.038
regionalization GO:0003002 416 0.037
organelle fission GO:0048285 340 0.037
negative regulation of cellular catabolic process GO:0031330 34 0.036
regulation of meiosis GO:0040020 3 0.036
regulation of cellular ketone metabolic process GO:0010565 3 0.035
positive regulation of signaling GO:0023056 243 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.034
histone h4 acetylation GO:0043967 13 0.034
negative regulation of response to stimulus GO:0048585 258 0.033
cellular macromolecule localization GO:0070727 220 0.033
single organism catabolic process GO:0044712 228 0.033
protein acetylation GO:0006473 39 0.033
nuclear division GO:0000280 332 0.033
oxoacid metabolic process GO:0043436 103 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
atp dependent chromatin remodeling GO:0043044 22 0.032
spermatogenesis GO:0007283 200 0.032
negative regulation of cell cycle GO:0045786 116 0.031
regulation of organelle organization GO:0033043 196 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
protein modification by small protein conjugation GO:0032446 79 0.031
appendage development GO:0048736 401 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
gene silencing by rna GO:0031047 57 0.030
cellular protein localization GO:0034613 160 0.030
positive regulation of phosphate metabolic process GO:0045937 139 0.030
protein maturation GO:0051604 71 0.029
regulation of chromatin organization GO:1902275 32 0.029
dna conformation change GO:0071103 105 0.029
regulation of catabolic process GO:0009894 170 0.028
regulation of response to stress GO:0080134 200 0.028
positive regulation of gene expression GO:0010628 290 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
protein acylation GO:0043543 42 0.028
regulation of cellular component biogenesis GO:0044087 201 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
rna splicing GO:0008380 83 0.027
apoptotic process GO:0006915 159 0.027
cytoplasmic transport GO:0016482 130 0.027
neuron projection guidance GO:0097485 241 0.027
nucleoside triphosphate metabolic process GO:0009141 120 0.026
regulation of cell division GO:0051302 72 0.026
nucleosome organization GO:0034728 59 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.026
imaginal disc derived appendage development GO:0048737 399 0.025
chromatin assembly or disassembly GO:0006333 52 0.025
endomembrane system organization GO:0010256 119 0.025
determination of adult lifespan GO:0008340 137 0.025
neurological system process GO:0050877 358 0.024
ncrna metabolic process GO:0034660 43 0.024
regulation of chromosome organization GO:0033044 64 0.024
morphogenesis of follicular epithelium GO:0016333 36 0.024
response to bacterium GO:0009617 198 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
cullin deneddylation GO:0010388 3 0.024
Human
protein localization to organelle GO:0033365 82 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
anterior posterior pattern specification GO:0009952 136 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
purine nucleotide catabolic process GO:0006195 109 0.023
peptidyl amino acid modification GO:0018193 105 0.023
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
cellular response to organic substance GO:0071310 132 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
maintenance of protein location in cell GO:0032507 26 0.022
death GO:0016265 284 0.022
cell fate determination GO:0001709 91 0.021
internal peptidyl lysine acetylation GO:0018393 38 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
regulation of notch signaling pathway GO:0008593 100 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.020
phosphorylation GO:0016310 294 0.020
rna splicing via transesterification reactions GO:0000375 73 0.020
synaptic transmission GO:0007268 288 0.020
cell death GO:0008219 279 0.020
single organism behavior GO:0044708 391 0.020
positive regulation of molecular function GO:0044093 136 0.020
ion transport GO:0006811 145 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
immune system process GO:0002376 347 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
macromolecular complex assembly GO:0065003 256 0.019
regulation of nuclear division GO:0051783 58 0.018
mitotic spindle organization GO:0007052 220 0.018
organic acid metabolic process GO:0006082 103 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of cellular protein catabolic process GO:1903362 44 0.018
purine containing compound catabolic process GO:0072523 112 0.018
posttranscriptional gene silencing GO:0016441 46 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
organelle assembly GO:0070925 198 0.018
response to anesthetic GO:0072347 9 0.018
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.018
asymmetric protein localization GO:0008105 33 0.018
blastoderm segmentation GO:0007350 159 0.018
regulation of immune system process GO:0002682 176 0.017
golgi vesicle transport GO:0048193 27 0.017
response to abiotic stimulus GO:0009628 341 0.017
cell motility GO:0048870 251 0.017
male gamete generation GO:0048232 201 0.017
single organism intracellular transport GO:1902582 207 0.017
nitrogen compound transport GO:0071705 85 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
negative regulation of cell communication GO:0010648 223 0.017
dna packaging GO:0006323 91 0.016
cellular protein complex assembly GO:0043623 71 0.016
synapse organization GO:0050808 196 0.016
snrna 3 end processing GO:0034472 14 0.016
lipid metabolic process GO:0006629 121 0.016
cellular amine metabolic process GO:0044106 12 0.016
negative regulation of erbb signaling pathway GO:1901185 29 0.016
chemotaxis GO:0006935 249 0.016
negative regulation of signal transduction GO:0009968 206 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
regulation of apoptotic process GO:0042981 130 0.015
histone mrna metabolic process GO:0008334 8 0.015
mrna processing GO:0006397 104 0.015
cytoskeleton dependent cytokinesis GO:0061640 81 0.015
locomotory behavior GO:0007626 176 0.015
regulation of hydrolase activity GO:0051336 97 0.015
peptidyl lysine acetylation GO:0018394 39 0.015
developmental maturation GO:0021700 172 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
regulation of mrna splicing via spliceosome GO:0048024 64 0.015
maintenance of protein location GO:0045185 28 0.015
genitalia development GO:0048806 26 0.015
protein processing GO:0016485 68 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
negative regulation of sister chromatid segregation GO:0033046 13 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
positive regulation of protein modification process GO:0031401 58 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.014
protein complex assembly GO:0006461 200 0.014
cellular ketone metabolic process GO:0042180 24 0.014
negative regulation of catabolic process GO:0009895 36 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
mrna metabolic process GO:0016071 124 0.014
phagocytosis GO:0006909 215 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
protein transport GO:0015031 155 0.014
membrane organization GO:0061024 112 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
maintenance of location in cell GO:0051651 28 0.014
ribonucleotide catabolic process GO:0009261 109 0.013
amine metabolic process GO:0009308 12 0.013
tripartite regional subdivision GO:0007351 103 0.013
regulation of protein stability GO:0031647 43 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
reproductive structure development GO:0048608 74 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
sperm individualization GO:0007291 48 0.013
mrna splicing via spliceosome GO:0000398 73 0.013
regulation of histone h3 k9 methylation GO:0051570 3 0.013
negative regulation of protein catabolic process GO:0042177 17 0.013
nuclear transport GO:0051169 72 0.013
cellular response to chemical stimulus GO:0070887 199 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
regulation of cell development GO:0060284 215 0.012
negative regulation of molecular function GO:0044092 51 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
histone deubiquitination GO:0016578 8 0.012
regulation of protein processing GO:0070613 32 0.012
axon development GO:0061564 297 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
appendage morphogenesis GO:0035107 397 0.012
establishment of protein localization GO:0045184 163 0.012
single organism membrane organization GO:0044802 93 0.012
cellular response to abiotic stimulus GO:0071214 58 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
protein targeting GO:0006605 64 0.011
atp biosynthetic process GO:0006754 2 0.011
secretion GO:0046903 109 0.011
protein localization to nucleus GO:0034504 55 0.011
establishment of nucleus localization GO:0040023 26 0.011
regulation of protein catabolic process GO:0042176 55 0.011
regulation of nervous system development GO:0051960 248 0.011
sex differentiation GO:0007548 81 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
mitotic nuclear division GO:0007067 213 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
development of primary sexual characteristics GO:0045137 50 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
detection of stimulus GO:0051606 156 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
regulation of cell differentiation GO:0045595 302 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.010
regulation of synaptic transmission GO:0050804 69 0.010
protein dna complex subunit organization GO:0071824 86 0.010
notch signaling pathway GO:0007219 120 0.010
meiotic nuclear division GO:0007126 151 0.010
signal transduction in response to dna damage GO:0042770 3 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
response to organic substance GO:0010033 284 0.010
negative regulation of cellular biosynthetic process GO:0031327 277 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
gene silencing by mirna GO:0035195 22 0.010
negative regulation of smoothened signaling pathway GO:0045879 16 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010
gene silencing GO:0016458 138 0.010
reproductive system development GO:0061458 74 0.010
cell migration GO:0016477 238 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010

CSN6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025