Drosophila melanogaster

46 known processes

Ptp4E (Dmel_CG6899)

Protein tyrosine phosphatase 4E

(Aliases: PTP4E,PtP4E,CG6899,DPTP4E,Dmel\CG6899,R-PTP 4E,CT21187)

Ptp4E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.335
cholesterol homeostasis GO:0042632 3 0.106
alcohol metabolic process GO:0006066 25 0.097
positive regulation of response to stimulus GO:0048584 323 0.095
Human Mouse
sterol homeostasis GO:0055092 4 0.093
single organism behavior GO:0044708 391 0.086
Fly
actomyosin structure organization GO:0031032 56 0.082
chemical homeostasis GO:0048878 92 0.079
vesicle mediated transport GO:0016192 381 0.075
cell migration GO:0016477 238 0.074
Human Mouse
cell projection assembly GO:0030031 94 0.073
Mouse
morphogenesis of an epithelium GO:0002009 276 0.069
lateral inhibition GO:0046331 206 0.064
protein complex assembly GO:0006461 200 0.062
cell cell signaling involved in cell fate commitment GO:0045168 210 0.062
homeostatic process GO:0042592 199 0.059
cell death GO:0008219 279 0.059
tube development GO:0035295 244 0.055
protein modification process GO:0036211 438 0.053
Human Mouse Rat Fly
embryonic morphogenesis GO:0048598 206 0.051
Mouse
regulation of protein metabolic process GO:0051246 256 0.048
Human Mouse
male gamete generation GO:0048232 201 0.046
death GO:0016265 284 0.045
oxidation reduction process GO:0055114 123 0.045
rna processing GO:0006396 147 0.045
regulation of apoptotic process GO:0042981 130 0.042
positive regulation of cell communication GO:0010647 250 0.042
Human
organelle assembly GO:0070925 198 0.042
spermatid development GO:0007286 98 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
cellular lipid metabolic process GO:0044255 83 0.040
programmed cell death GO:0012501 257 0.039
spermatid differentiation GO:0048515 114 0.039
axonogenesis GO:0007409 290 0.038
apoptotic process GO:0006915 159 0.038
response to wounding GO:0009611 94 0.038
Mouse
positive regulation of signaling GO:0023056 243 0.037
Human
embryonic development via the syncytial blastoderm GO:0001700 148 0.037
regulation of molecular function GO:0065009 217 0.037
Human Mouse
lipid metabolic process GO:0006629 121 0.036
protein maturation GO:0051604 71 0.035
actin cytoskeleton organization GO:0030036 206 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.035
negative regulation of cellular protein metabolic process GO:0032269 85 0.035
Human Mouse
regulation of programmed cell death GO:0043067 152 0.035
regulation of cellular ketone metabolic process GO:0010565 3 0.035
regulation of localization GO:0032879 275 0.035
Human Mouse
cellular ketone metabolic process GO:0042180 24 0.034
organic hydroxy compound metabolic process GO:1901615 83 0.034
tissue morphogenesis GO:0048729 297 0.034
mrna splicing via spliceosome GO:0000398 73 0.033
adult behavior GO:0030534 137 0.032
macromolecular complex assembly GO:0065003 256 0.032
protein complex biogenesis GO:0070271 201 0.030
sister chromatid segregation GO:0000819 92 0.030
cellular response to dna damage stimulus GO:0006974 223 0.030
regulation of cellular amine metabolic process GO:0033238 3 0.029
cellular protein modification process GO:0006464 438 0.029
Human Mouse Rat Fly
cell adhesion GO:0007155 136 0.028
Human Mouse
carboxylic acid metabolic process GO:0019752 92 0.028
regulation of catalytic activity GO:0050790 185 0.028
Human Mouse
pigment metabolic process GO:0042440 84 0.027
cell maturation GO:0048469 144 0.027
response to abiotic stimulus GO:0009628 341 0.027
Mouse
regulation of cellular localization GO:0060341 136 0.027
proteolysis GO:0006508 192 0.026
regulation of immune system process GO:0002682 176 0.026
Human Mouse
positive regulation of signal transduction GO:0009967 223 0.026
Human
negative regulation of cell communication GO:0010648 223 0.025
Human Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.025
Human Mouse
response to monosaccharide GO:0034284 4 0.025
regionalization GO:0003002 416 0.024
actin filament based process GO:0030029 220 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
regulation of cell death GO:0010941 173 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
cation transmembrane transport GO:0098655 88 0.024
catabolic process GO:0009056 409 0.024
wound healing GO:0042060 75 0.023
Mouse
mrna metabolic process GO:0016071 124 0.023
cellular amine metabolic process GO:0044106 12 0.023
organic acid metabolic process GO:0006082 103 0.023
anterior posterior pattern specification GO:0009952 136 0.023
actin filament organization GO:0007015 126 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
oxoacid metabolic process GO:0043436 103 0.022
positive regulation of gtpase activity GO:0043547 43 0.022
axon guidance GO:0007411 233 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
immune system process GO:0002376 347 0.021
Human Mouse
tube morphogenesis GO:0035239 191 0.021
growth GO:0040007 359 0.021
Human
regulation of intracellular signal transduction GO:1902531 236 0.021
Human Mouse
positive regulation of programmed cell death GO:0043068 62 0.020
mrna processing GO:0006397 104 0.020
regulation of response to stress GO:0080134 200 0.020
Mouse
negative regulation of protein metabolic process GO:0051248 85 0.020
Human Mouse
monovalent inorganic cation transport GO:0015672 40 0.020
negative regulation of gene expression GO:0010629 387 0.020
endocytosis GO:0006897 310 0.019
oocyte differentiation GO:0009994 145 0.019
developmental programmed cell death GO:0010623 138 0.019
sensory perception GO:0007600 196 0.019
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 27 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
Human Mouse
amine metabolic process GO:0009308 12 0.018
exocrine system development GO:0035272 162 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
Human Mouse
endoderm formation GO:0001706 3 0.018
notch signaling pathway GO:0007219 120 0.018
regulation of cell proliferation GO:0042127 163 0.017
Human Mouse
spindle organization GO:0007051 253 0.017
cellular homeostasis GO:0019725 80 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
establishment of localization in cell GO:0051649 402 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
regulation of cell differentiation GO:0045595 302 0.016
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.016
regulation of hydrolase activity GO:0051336 97 0.016
protein secretion GO:0009306 45 0.016
positive regulation of nucleoside metabolic process GO:0045979 47 0.016
intracellular signal transduction GO:0035556 300 0.016
Human Mouse
spermatogenesis GO:0007283 200 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.015
Human Mouse
single organism cellular localization GO:1902580 180 0.015
cell motility GO:0048870 251 0.015
Human Mouse
metal ion transport GO:0030001 74 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
Human Mouse
protein phosphorylation GO:0006468 169 0.015
Human Mouse
eye development GO:0001654 323 0.015
regulation of proteolysis GO:0030162 87 0.015
membrane organization GO:0061024 112 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
Human Mouse
immune response regulating signaling pathway GO:0002764 2 0.015
Human Mouse
peptidyl amino acid modification GO:0018193 105 0.014
rna localization GO:0006403 115 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
regulation of phosphorylation GO:0042325 147 0.014
Human Mouse
negative regulation of immune system process GO:0002683 50 0.014
Human Mouse
regulation of establishment of protein localization GO:0070201 61 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
Human
secondary metabolic process GO:0019748 75 0.014
regulation of transport GO:0051049 181 0.014
smoothened signaling pathway GO:0007224 49 0.014
aging GO:0007568 143 0.014
positive regulation of immune system process GO:0002684 68 0.013
Human Mouse
rna splicing GO:0008380 83 0.013
biological adhesion GO:0022610 138 0.013
Human Mouse
phagocytosis GO:0006909 215 0.013
response to hexose GO:0009746 3 0.013
tissue death GO:0016271 102 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.013
negative regulation of signal transduction GO:0009968 206 0.013
Human Mouse
metal ion homeostasis GO:0055065 44 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
cation transport GO:0006812 110 0.013
salivary gland development GO:0007431 162 0.013
chemotaxis GO:0006935 249 0.012
compound eye development GO:0048749 307 0.012
aromatic compound catabolic process GO:0019439 166 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
organic substance catabolic process GO:1901575 308 0.012
regulation of reproductive process GO:2000241 54 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
oocyte development GO:0048599 124 0.012
digestive system development GO:0055123 149 0.012
kidney development GO:0001822 3 0.012
Human Mouse
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
negative regulation of catalytic activity GO:0043086 42 0.012
Human Mouse
retina development in camera type eye GO:0060041 4 0.011
developmental maturation GO:0021700 172 0.011
response to lipopolysaccharide GO:0032496 4 0.011
cell proliferation GO:0008283 299 0.011
Human Mouse
dephosphorylation GO:0016311 51 0.011
Human Mouse Rat Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.011
peripheral nervous system development GO:0007422 52 0.011
regulation of peptidase activity GO:0052547 39 0.011
pole plasm oskar mrna localization GO:0045451 46 0.011
neurological system process GO:0050877 358 0.011
Mouse Fly
protein localization GO:0008104 284 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
Rat
cellular chemical homeostasis GO:0055082 40 0.011
response to extracellular stimulus GO:0009991 116 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
body morphogenesis GO:0010171 2 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
response to nutrient levels GO:0031667 114 0.011
protein transport GO:0015031 155 0.011
ion transport GO:0006811 145 0.011
response to light stimulus GO:0009416 124 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
Human
positive regulation of lipid metabolic process GO:0045834 4 0.010
camera type eye development GO:0043010 4 0.010
salivary gland morphogenesis GO:0007435 145 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.010
cell division GO:0051301 248 0.010
cell cell junction organization GO:0045216 55 0.010
Human Mouse
response to radiation GO:0009314 155 0.010
regulation of membrane potential GO:0042391 35 0.010

Ptp4E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
Human
urinary system disease DOID:18 0 0.020
Human
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
nervous system disease DOID:863 0 0.016