Drosophila melanogaster

2 known processes

LysD (Dmel_CG9118)

Lysozyme D

(Aliases: Dmel\CG9118,lysD,CG9118)

LysD biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to gram positive bacterium GO:0050830 41 0.709
Mouse Rat
regulation of defense response GO:0031347 102 0.484
Fly
response to bacterium GO:0009617 198 0.430
Mouse Rat Fly
negative regulation of immune system process GO:0002683 50 0.387
Fly
single fertilization GO:0007338 24 0.386
Mouse
immune response GO:0006955 246 0.330
Fly
anatomical structure homeostasis GO:0060249 97 0.326
Human
regulation of response to stress GO:0080134 200 0.320
Fly
regulation of immune system process GO:0002682 176 0.319
Fly
gland morphogenesis GO:0022612 145 0.309
Fly
innate immune response GO:0045087 144 0.308
Fly
cell recognition GO:0008037 102 0.307
Mouse
negative regulation of response to stimulus GO:0048585 258 0.288
Fly
salivary gland cell autophagic cell death GO:0035071 83 0.284
Fly
defense response GO:0006952 300 0.269
Mouse Rat Fly
fertilization GO:0009566 26 0.252
Mouse
salivary gland development GO:0007431 162 0.229
Fly
autophagic cell death GO:0048102 83 0.223
Fly
exocrine system development GO:0035272 162 0.223
Fly
homeostatic process GO:0042592 199 0.200
Human
salivary gland morphogenesis GO:0007435 145 0.193
Fly
defense response to gram negative bacterium GO:0050829 94 0.187
Mouse Rat Fly
defense response to bacterium GO:0042742 178 0.187
Mouse Rat Fly
immune system process GO:0002376 347 0.178
Fly
death GO:0016265 284 0.174
Fly
salivary gland histolysis GO:0035070 88 0.164
Fly
regulation of immune response GO:0050776 118 0.138
Fly
developmental programmed cell death GO:0010623 138 0.132
Fly
tissue homeostasis GO:0001894 36 0.126
Human
response to external biotic stimulus GO:0043207 293 0.125
Mouse Rat Fly
tissue death GO:0016271 102 0.118
Fly
negative regulation of defense response GO:0031348 35 0.105
Fly
histolysis GO:0007559 102 0.094
Fly
cell death GO:0008219 279 0.089
Fly
retina homeostasis GO:0001895 13 0.058
Human
programmed cell death GO:0012501 257 0.056
Fly
appendage morphogenesis GO:0035107 397 0.056
positive regulation of cell communication GO:0010647 250 0.054
imaginal disc derived appendage development GO:0048737 399 0.054
appendage development GO:0048736 401 0.054
imaginal disc derived appendage morphogenesis GO:0035114 395 0.053
positive regulation of response to stimulus GO:0048584 323 0.050
wing disc morphogenesis GO:0007472 344 0.050
small molecule metabolic process GO:0044281 305 0.050
organic acid metabolic process GO:0006082 103 0.047
response to other organism GO:0051707 293 0.047
Mouse Rat Fly
multicellular organismal homeostasis GO:0048871 41 0.047
Human
regulation of multicellular organismal development GO:2000026 414 0.045
gland development GO:0048732 191 0.043
Fly
carboxylic acid metabolic process GO:0019752 92 0.042
positive regulation of signaling GO:0023056 243 0.042
developmental growth GO:0048589 280 0.040
imaginal disc derived wing morphogenesis GO:0007476 337 0.039
negative regulation of innate immune response GO:0045824 30 0.036
Fly
regulation of cell differentiation GO:0045595 302 0.035
response to organic substance GO:0010033 284 0.035
post embryonic appendage morphogenesis GO:0035120 385 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.034
catabolic process GO:0009056 409 0.032
intracellular signal transduction GO:0035556 300 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
epithelial cell differentiation GO:0030855 322 0.029
oxoacid metabolic process GO:0043436 103 0.027
growth GO:0040007 359 0.027
protein modification process GO:0036211 438 0.027
organic substance catabolic process GO:1901575 308 0.026
cellular catabolic process GO:0044248 372 0.025
organonitrogen compound metabolic process GO:1901564 318 0.024
organic hydroxy compound metabolic process GO:1901615 83 0.024
response to lipopolysaccharide GO:0032496 4 0.024
regulation of cell cycle GO:0051726 291 0.023
negative regulation of gene expression GO:0010629 387 0.023
response to biotic stimulus GO:0009607 294 0.022
Mouse Rat Fly
regulation of localization GO:0032879 275 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
regionalization GO:0003002 416 0.021
macromolecular complex assembly GO:0065003 256 0.021
cellular amine metabolic process GO:0044106 12 0.021
cellular protein modification process GO:0006464 438 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
neurological system process GO:0050877 358 0.020
negative regulation of developmental process GO:0051093 201 0.019
regulation of cell development GO:0060284 215 0.019
regulation of transport GO:0051049 181 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
phosphorylation GO:0016310 294 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
amine metabolic process GO:0009308 12 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.017
single organism catabolic process GO:0044712 228 0.017
negative regulation of signal transduction GO:0009968 206 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
organic substance transport GO:0071702 257 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
intracellular transport GO:0046907 228 0.016
tissue morphogenesis GO:0048729 297 0.016
response to oxygen containing compound GO:1901700 200 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
body morphogenesis GO:0010171 2 0.016
regulation of growth GO:0040008 233 0.015
response to abiotic stimulus GO:0009628 341 0.015
epithelial cell development GO:0002064 274 0.015
negative regulation of signaling GO:0023057 219 0.015
cellular response to organic substance GO:0071310 132 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
cell proliferation GO:0008283 299 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
organophosphate metabolic process GO:0019637 195 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
forebrain development GO:0030900 2 0.015
regulation of phosphate metabolic process GO:0019220 210 0.014
eggshell formation GO:0030703 105 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
regulation of molecular function GO:0065009 217 0.014
phagocytosis GO:0006909 215 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
chemosensory behavior GO:0007635 106 0.014
mitotic nuclear division GO:0007067 213 0.014
positive regulation of cellular component organization GO:0051130 156 0.013
phosphatidylcholine metabolic process GO:0046470 3 0.013
compound eye development GO:0048749 307 0.013
negative regulation of immune response GO:0050777 39 0.013
Fly
establishment of localization in cell GO:0051649 402 0.013
protein complex biogenesis GO:0070271 201 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
maintenance of location GO:0051235 73 0.013
kidney development GO:0001822 3 0.013
rhythmic process GO:0048511 106 0.013
segmentation GO:0035282 207 0.013
response to nitrogen compound GO:1901698 90 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
cellular lipid metabolic process GO:0044255 83 0.013
single organism behavior GO:0044708 391 0.013
cholesterol transport GO:0030301 2 0.013
regulation of innate immune response GO:0045088 71 0.013
Fly
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
cell division GO:0051301 248 0.012
regulation of protein metabolic process GO:0051246 256 0.012
biological adhesion GO:0022610 138 0.012
respiratory system development GO:0060541 213 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
protein localization GO:0008104 284 0.012
spermatogenesis GO:0007283 200 0.012
sterol homeostasis GO:0055092 4 0.012
vesicle mediated transport GO:0016192 381 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of developmental growth GO:0048638 174 0.012
immune response activating signal transduction GO:0002757 2 0.012
embryonic pattern specification GO:0009880 174 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
phospholipid homeostasis GO:0055091 1 0.012
regulation of phosphorylation GO:0042325 147 0.012
lipid metabolic process GO:0006629 121 0.012
anion homeostasis GO:0055081 3 0.011
male gamete generation GO:0048232 201 0.011
positive regulation of signal transduction GO:0009967 223 0.011
cholesterol homeostasis GO:0042632 3 0.011
regulation of organelle organization GO:0033043 196 0.011
macromolecule catabolic process GO:0009057 161 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
cellular amide metabolic process GO:0043603 80 0.011
organ growth GO:0035265 56 0.011
response to temperature stimulus GO:0009266 106 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
ovarian follicle cell development GO:0030707 248 0.011
defense response to other organism GO:0098542 225 0.011
Mouse Rat Fly
negative regulation of cell communication GO:0010648 223 0.011
single organism biosynthetic process GO:0044711 206 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
cell motility GO:0048870 251 0.010
protein phosphorylation GO:0006468 169 0.010
proteolysis GO:0006508 192 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
blastoderm segmentation GO:0007350 159 0.010
positive regulation of transport GO:0051050 92 0.010
single organism intracellular transport GO:1902582 207 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
sensory organ morphogenesis GO:0090596 260 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
response to nutrient levels GO:0031667 114 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
circadian rhythm GO:0007623 105 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010

LysD disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.997
Human
amyloidosis DOID:9120 0 0.997
Human
acquired metabolic disease DOID:0060158 0 0.997
Human
familial visceral amyloidosis DOID:0050636 0 0.997
Human
disease of anatomical entity DOID:7 0 0.026
inherited metabolic disorder DOID:655 0 0.017
familial hyperlipidemia DOID:1168 0 0.010
lipid metabolism disorder DOID:3146 0 0.010
familial combined hyperlipidemia DOID:13809 0 0.010
diabetes mellitus DOID:9351 0 0.010
type 2 diabetes mellitus DOID:9352 0 0.010
carbohydrate metabolism disease DOID:0050013 0 0.010
glucose metabolism disease DOID:4194 0 0.010