Drosophila melanogaster

99 known processes

l(3)neo38 (Dmel_CG6930)

lethal (3) neo38

(Aliases: CG31364,Dmel\CG6930,CG6930,CG14725,BcDNA:SD16005)

l(3)neo38 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutathione metabolic process GO:0006749 37 0.658
cellular modified amino acid metabolic process GO:0006575 45 0.222
sulfur compound metabolic process GO:0006790 59 0.214
cellular amide metabolic process GO:0043603 80 0.171
cellular amino acid metabolic process GO:0006520 61 0.155
oxoacid metabolic process GO:0043436 103 0.102
programmed cell death GO:0012501 257 0.070
small molecule metabolic process GO:0044281 305 0.067
body morphogenesis GO:0010171 2 0.065
carboxylic acid metabolic process GO:0019752 92 0.064
positive regulation of macromolecule metabolic process GO:0010604 405 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.056
lateral inhibition GO:0046331 206 0.048
chromosome organization GO:0051276 360 0.048
establishment of localization in cell GO:0051649 402 0.048
negative regulation of biosynthetic process GO:0009890 277 0.048
transcription from rna polymerase ii promoter GO:0006366 368 0.047
cell cell signaling involved in cell fate commitment GO:0045168 210 0.045
male gamete generation GO:0048232 201 0.044
organic acid metabolic process GO:0006082 103 0.044
negative regulation of nucleic acid templated transcription GO:1903507 240 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
positive regulation of rna metabolic process GO:0051254 271 0.041
regulation of organelle organization GO:0033043 196 0.040
cellular protein modification process GO:0006464 438 0.040
vesicle mediated transport GO:0016192 381 0.040
Fly
negative regulation of gene expression GO:0010629 387 0.039
wing disc morphogenesis GO:0007472 344 0.039
positive regulation of biosynthetic process GO:0009891 316 0.036
immune system process GO:0002376 347 0.036
cell death GO:0008219 279 0.035
negative regulation of rna metabolic process GO:0051253 251 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
imaginal disc pattern formation GO:0007447 91 0.032
rna processing GO:0006396 147 0.032
response to abiotic stimulus GO:0009628 341 0.031
single organism membrane organization GO:0044802 93 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.030
developmental programmed cell death GO:0010623 138 0.030
endocytosis GO:0006897 310 0.030
Fly
gene silencing GO:0016458 138 0.030
chromatin organization GO:0006325 207 0.030
hindbrain development GO:0030902 2 0.030
single organism behavior GO:0044708 391 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.029
actin cytoskeleton organization GO:0030036 206 0.029
embryonic development via the syncytial blastoderm GO:0001700 148 0.029
embryo development ending in birth or egg hatching GO:0009792 152 0.029
forebrain development GO:0030900 2 0.028
negative regulation of transcription dna templated GO:0045892 237 0.028
apoptotic process involved in morphogenesis GO:0060561 3 0.028
posttranscriptional regulation of gene expression GO:0010608 145 0.027
organic substance transport GO:0071702 257 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
immune response GO:0006955 246 0.026
negative regulation of signal transduction GO:0009968 206 0.025
negative regulation of response to stimulus GO:0048585 258 0.024
negative regulation of signaling GO:0023057 219 0.024
response to lipopolysaccharide GO:0032496 4 0.024
positive regulation of gene expression GO:0010628 290 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
phagocytosis GO:0006909 215 0.023
Fly
positive regulation of transcription dna templated GO:0045893 266 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
respiratory system development GO:0060541 213 0.022
intracellular transport GO:0046907 228 0.022
growth GO:0040007 359 0.022
response to external biotic stimulus GO:0043207 293 0.022
regulation of cell proliferation GO:0042127 163 0.022
intracellular signal transduction GO:0035556 300 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
axon guidance GO:0007411 233 0.021
cell proliferation GO:0008283 299 0.021
response to oxygen containing compound GO:1901700 200 0.021
anatomical structure homeostasis GO:0060249 97 0.021
regulation of gene silencing GO:0060968 63 0.021
spermatogenesis GO:0007283 200 0.021
positive regulation of cell communication GO:0010647 250 0.021
regulation of nervous system development GO:0051960 248 0.020
epithelial cell differentiation GO:0030855 322 0.020
taxis GO:0042330 304 0.020
regulation of programmed cell death GO:0043067 152 0.020
centrosome organization GO:0051297 163 0.020
endomembrane system organization GO:0010256 119 0.020
synapse organization GO:0050808 196 0.020
actin filament organization GO:0007015 126 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
regulation of cell cycle GO:0051726 291 0.020
death GO:0016265 284 0.020
regulation of growth GO:0040008 233 0.020
positive regulation of cell motility GO:2000147 3 0.020
regulation of cellular component size GO:0032535 98 0.020
compound eye morphogenesis GO:0001745 249 0.019
regulation of cell shape GO:0008360 113 0.019
appendage development GO:0048736 401 0.019
immune response regulating signaling pathway GO:0002764 2 0.019
regulation of transport GO:0051049 181 0.019
organelle assembly GO:0070925 198 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
imaginal disc derived wing vein specification GO:0007474 48 0.019
negative regulation of erbb signaling pathway GO:1901185 29 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
positive regulation of signaling GO:0023056 243 0.019
negative regulation of cell communication GO:0010648 223 0.019
regulation of developmental growth GO:0048638 174 0.018
limb development GO:0060173 1 0.018
single organism intracellular transport GO:1902582 207 0.018
positive regulation of signal transduction GO:0009967 223 0.018
establishment of protein localization GO:0045184 163 0.018
membrane organization GO:0061024 112 0.018
chromatin silencing GO:0006342 76 0.018
regionalization GO:0003002 416 0.018
neuromuscular junction development GO:0007528 149 0.018
innate immune response GO:0045087 144 0.018
wound healing GO:0042060 75 0.018
regulation of meiosis GO:0040020 3 0.018
protein complex biogenesis GO:0070271 201 0.018
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
regulation of erbb signaling pathway GO:1901184 42 0.017
organelle fission GO:0048285 340 0.017
eye development GO:0001654 323 0.017
axon development GO:0061564 297 0.017
actin filament based process GO:0030029 220 0.017
developmental growth GO:0048589 280 0.017
protein modification process GO:0036211 438 0.017
immune response activating signal transduction GO:0002757 2 0.017
cellular catabolic process GO:0044248 372 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
regulation of anatomical structure size GO:0090066 163 0.017
response to organic substance GO:0010033 284 0.017
defense response GO:0006952 300 0.017
imaginal disc derived appendage development GO:0048737 399 0.016
chromatin modification GO:0016568 147 0.016
response to other organism GO:0051707 293 0.016
neurological system process GO:0050877 358 0.016
camera type eye development GO:0043010 4 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.016
spermatid differentiation GO:0048515 114 0.016
mrna processing GO:0006397 104 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
alternative mrna splicing via spliceosome GO:0000380 60 0.016
proteolysis GO:0006508 192 0.016
mitotic nuclear division GO:0007067 213 0.016
regulation of protein metabolic process GO:0051246 256 0.016
heterocycle catabolic process GO:0046700 166 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
head development GO:0060322 135 0.016
protein transport GO:0015031 155 0.016
compound eye development GO:0048749 307 0.015
microtubule organizing center organization GO:0031023 168 0.015
stem cell fate commitment GO:0048865 25 0.015
regulation of cell cycle process GO:0010564 181 0.015
response to wounding GO:0009611 94 0.015
aromatic compound catabolic process GO:0019439 166 0.015
regulation of cell death GO:0010941 173 0.015
protein complex assembly GO:0006461 200 0.015
retina development in camera type eye GO:0060041 4 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
neuroblast fate commitment GO:0014017 19 0.015
activation of innate immune response GO:0002218 4 0.015
regulation of molecular function GO:0065009 217 0.015
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.015
response to biotic stimulus GO:0009607 294 0.015
regulation of rna splicing GO:0043484 69 0.015
cellular response to organic substance GO:0071310 132 0.015
catabolic process GO:0009056 409 0.015
mitotic dna integrity checkpoint GO:0044774 75 0.015
open tracheal system development GO:0007424 204 0.015
spindle organization GO:0007051 253 0.014
brain development GO:0007420 120 0.014
homeostatic process GO:0042592 199 0.014
positive regulation of organelle organization GO:0010638 65 0.014
histone modification GO:0016570 106 0.014
organic substance catabolic process GO:1901575 308 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
biological adhesion GO:0022610 138 0.014
single organism membrane fusion GO:0044801 42 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
neuropeptide signaling pathway GO:0007218 45 0.014
cell division GO:0051301 248 0.014
regulation of defense response GO:0031347 102 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
regulation of synapse organization GO:0050807 110 0.014
protein localization GO:0008104 284 0.014
transmembrane transport GO:0055085 139 0.014
adult behavior GO:0030534 137 0.014
gene silencing by rna GO:0031047 57 0.014
cilium organization GO:0044782 41 0.014
mrna metabolic process GO:0016071 124 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
wing disc pattern formation GO:0035222 66 0.014
cell cycle phase transition GO:0044770 140 0.014
sterol homeostasis GO:0055092 4 0.014
regulation of catalytic activity GO:0050790 185 0.013
notch signaling pathway GO:0007219 120 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
triglyceride catabolic process GO:0019433 3 0.013
regulation of apoptotic process GO:0042981 130 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
ras protein signal transduction GO:0007265 88 0.013
epithelial cell development GO:0002064 274 0.013
regulation of catabolic process GO:0009894 170 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
limb morphogenesis GO:0035108 1 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
negative regulation of gene expression epigenetic GO:0045814 77 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
telencephalon development GO:0021537 2 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
appendage morphogenesis GO:0035107 397 0.013
negative regulation of immune system process GO:0002683 50 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
defense response to fungus GO:0050832 48 0.013
regulation of localization GO:0032879 275 0.013
compound eye photoreceptor development GO:0042051 78 0.013
macromolecular complex assembly GO:0065003 256 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
mrna splicing via spliceosome GO:0000398 73 0.013
mitotic cell cycle phase transition GO:0044772 138 0.012
connective tissue development GO:0061448 3 0.012
regulation of synapse assembly GO:0051963 94 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
chitin based cuticle development GO:0040003 49 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
chaeta morphogenesis GO:0008407 42 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
regulation of cell differentiation GO:0045595 302 0.012
macromolecule catabolic process GO:0009057 161 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
regulation of immune system process GO:0002682 176 0.012
eye morphogenesis GO:0048592 260 0.012
rna splicing GO:0008380 83 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
autophagy GO:0006914 108 0.012
response to radiation GO:0009314 155 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
sensory organ morphogenesis GO:0090596 260 0.012
neuroblast proliferation GO:0007405 74 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
single organism catabolic process GO:0044712 228 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
ovarian follicle cell development GO:0030707 248 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
neuroblast differentiation GO:0014016 29 0.012
positive regulation of developmental process GO:0051094 143 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
cell adhesion GO:0007155 136 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
covalent chromatin modification GO:0016569 106 0.012
spiracle morphogenesis open tracheal system GO:0035277 22 0.012
response to oxidative stress GO:0006979 86 0.012
negative regulation of cell death GO:0060548 81 0.012
behavioral response to ethanol GO:0048149 49 0.012
purine containing compound catabolic process GO:0072523 112 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
nuclear division GO:0000280 332 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
dna metabolic process GO:0006259 227 0.011
gland morphogenesis GO:0022612 145 0.011
cellular protein localization GO:0034613 160 0.011
secretion by cell GO:0032940 101 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
synapse assembly GO:0007416 143 0.011
erbb signaling pathway GO:0038127 58 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
centrosome cycle GO:0007098 137 0.011
chromatin remodeling GO:0006338 72 0.011
response to monosaccharide GO:0034284 4 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
exocrine system development GO:0035272 162 0.011
humoral immune response GO:0006959 117 0.011
regulation of proteolysis GO:0030162 87 0.011
mesenchymal cell development GO:0014031 1 0.011
tube development GO:0035295 244 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
cell fate specification GO:0001708 71 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
monocarboxylic acid transport GO:0015718 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
neuron recognition GO:0008038 101 0.011
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.011
dna damage checkpoint GO:0000077 78 0.011
positive regulation of cell migration GO:0030335 2 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
cation homeostasis GO:0055080 51 0.011
genital disc development GO:0035215 44 0.011
response to copper ion GO:0046688 4 0.011
metal ion homeostasis GO:0055065 44 0.011
intracellular protein transport GO:0006886 104 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
negative regulation of translation GO:0017148 28 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
spinal cord development GO:0021510 1 0.011
response to alcohol GO:0097305 95 0.011
regulation of mrna processing GO:0050684 71 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
dna packaging GO:0006323 91 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of response to stress GO:0080134 200 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
kidney development GO:0001822 3 0.010
establishment of synaptic vesicle localization GO:0097480 50 0.010
cellularization GO:0007349 90 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
salivary gland development GO:0007431 162 0.010
cellular macromolecule localization GO:0070727 220 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
establishment of vesicle localization GO:0051650 51 0.010
heart process GO:0003015 37 0.010
skin development GO:0043588 65 0.010
spermatid development GO:0007286 98 0.010
organonitrogen compound metabolic process GO:1901564 318 0.010
phototransduction GO:0007602 52 0.010
positive regulation of defense response GO:0031349 59 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
salivary gland histolysis GO:0035070 88 0.010
response to ethanol GO:0045471 59 0.010
cell maturation GO:0048469 144 0.010
regulation of chromosome organization GO:0033044 64 0.010
salivary gland morphogenesis GO:0007435 145 0.010
mitotic cell cycle checkpoint GO:0007093 88 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
protein targeting GO:0006605 64 0.010

l(3)neo38 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of metabolism DOID:0014667 0 0.015
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
inherited metabolic disorder DOID:655 0 0.011