Drosophila melanogaster

259 known processes

Mer (Dmel_CG14228)

Merlin

(Aliases: EMR2,BG01543,Dmerlin,Dmel\CG14228,CG14228,mer,D-Mer,Emr2)

Mer biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex assembly GO:0065003 256 0.971
single organism cellular localization GO:1902580 180 0.957
cellular response to organic substance GO:0071310 132 0.948
neurological system process GO:0050877 358 0.935
sensory organ morphogenesis GO:0090596 260 0.931
protein phosphorylation GO:0006468 169 0.921
embryo development ending in birth or egg hatching GO:0009792 152 0.897
Worm
spindle organization GO:0007051 253 0.892
Fly
meiotic nuclear division GO:0007126 151 0.871
enzyme linked receptor protein signaling pathway GO:0007167 179 0.844
protein complex assembly GO:0006461 200 0.827
compound eye development GO:0048749 307 0.821
response to organic substance GO:0010033 284 0.805
protein localization GO:0008104 284 0.798
protein localization to nucleus GO:0034504 55 0.782
Mouse
protein complex biogenesis GO:0070271 201 0.768
spermatogenesis GO:0007283 200 0.730
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.725
cellular ketone metabolic process GO:0042180 24 0.708
meiotic cell cycle process GO:1903046 132 0.695
intracellular signal transduction GO:0035556 300 0.689
protein targeting GO:0006605 64 0.680
hippo signaling GO:0035329 20 0.674
regulation of multicellular organismal development GO:2000026 414 0.671
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.656
cellular response to dna damage stimulus GO:0006974 223 0.652
negative regulation of signaling GO:0023057 219 0.649
Human Mouse
cellular macromolecule localization GO:0070727 220 0.646
purine containing compound metabolic process GO:0072521 155 0.634
purine nucleoside triphosphate metabolic process GO:0009144 119 0.628
small molecule metabolic process GO:0044281 305 0.604
response to oxidative stress GO:0006979 86 0.601
regulation of cellular ketone metabolic process GO:0010565 3 0.600
regulation of intracellular signal transduction GO:1902531 236 0.585
regulation of mitotic cell cycle GO:0007346 190 0.571
Fly
protein transport GO:0015031 155 0.565
regulation of phosphate metabolic process GO:0019220 210 0.532
response to alcohol GO:0097305 95 0.527
cell death GO:0008219 279 0.522
positive regulation of cellular component organization GO:0051130 156 0.516
Human Fly
regulation of cell cycle GO:0051726 291 0.516
tube morphogenesis GO:0035239 191 0.500
Mouse
intracellular protein transport GO:0006886 104 0.495
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.488
Human
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.488
determination of adult lifespan GO:0008340 137 0.478
protein import GO:0017038 55 0.473
organic acid metabolic process GO:0006082 103 0.470
regulation of cellular catabolic process GO:0031329 157 0.466
positive regulation of molecular function GO:0044093 136 0.461
protein localization to organelle GO:0033365 82 0.458
Mouse
glycosyl compound metabolic process GO:1901657 127 0.429
cell cycle phase transition GO:0044770 140 0.417
Fly
establishment of protein localization GO:0045184 163 0.400
cellular catabolic process GO:0044248 372 0.389
Fly
regulation of catalytic activity GO:0050790 185 0.385
Mouse
regulation of growth GO:0040008 233 0.383
nucleoside metabolic process GO:0009116 127 0.372
establishment of localization in cell GO:0051649 402 0.368
catabolic process GO:0009056 409 0.367
Fly
regulation of cell death GO:0010941 173 0.356
nucleoside triphosphate catabolic process GO:0009143 108 0.347
aging GO:0007568 143 0.343
eye photoreceptor cell differentiation GO:0001754 145 0.334
endomembrane system organization GO:0010256 119 0.330
carbohydrate derivative metabolic process GO:1901135 217 0.323
purine nucleoside catabolic process GO:0006152 112 0.311
positive regulation of phosphate metabolic process GO:0045937 139 0.310
negative regulation of cell communication GO:0010648 223 0.302
Human Mouse
response to radiation GO:0009314 155 0.301
positive regulation of catalytic activity GO:0043085 118 0.298
rho protein signal transduction GO:0007266 14 0.296
nucleobase containing small molecule metabolic process GO:0055086 174 0.293
germarium derived female germ line cyst formation GO:0030727 42 0.293
male gamete generation GO:0048232 201 0.292
regulation of localization GO:0032879 275 0.290
Mouse Fly
regulation of cytoskeleton organization GO:0051493 89 0.288
Human Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.287
transcription from rna polymerase ii promoter GO:0006366 368 0.286
purine ribonucleoside catabolic process GO:0046130 112 0.284
positive regulation of cellular catabolic process GO:0031331 95 0.281
cellular response to chemical stimulus GO:0070887 199 0.281
protein import into nucleus GO:0006606 51 0.279
cellular amine metabolic process GO:0044106 12 0.273
nucleoside triphosphate metabolic process GO:0009141 120 0.273
purine ribonucleotide metabolic process GO:0009150 145 0.267
response to oxygen containing compound GO:1901700 200 0.267
chromosome organization GO:0051276 360 0.267
Fly
compound eye photoreceptor cell differentiation GO:0001751 140 0.266
purine nucleotide catabolic process GO:0006195 109 0.264
negative regulation of rna biosynthetic process GO:1902679 240 0.261
mitotic cell cycle phase transition GO:0044772 138 0.260
Fly
endocytosis GO:0006897 310 0.256
positive regulation of catabolic process GO:0009896 105 0.255
purine nucleotide metabolic process GO:0006163 146 0.255
meiotic cell cycle GO:0051321 171 0.254
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.251
positive regulation of rna metabolic process GO:0051254 271 0.251
purine nucleoside metabolic process GO:0042278 127 0.247
muscle structure development GO:0061061 224 0.246
female meiotic division GO:0007143 70 0.245
ribose phosphate metabolic process GO:0019693 145 0.240
maintenance of protein location GO:0045185 28 0.239
nucleoside phosphate metabolic process GO:0006753 162 0.238
regulation of cell proliferation GO:0042127 163 0.238
cellular response to oxygen containing compound GO:1901701 79 0.235
regulation of cellular amine metabolic process GO:0033238 3 0.234
response to light stimulus GO:0009416 124 0.233
positive regulation of developmental process GO:0051094 143 0.230
Mouse
negative regulation of phosphate metabolic process GO:0045936 45 0.229
Human Mouse
ribonucleotide metabolic process GO:0009259 145 0.229
negative regulation of apoptotic process GO:0043066 63 0.228
negative regulation of signal transduction GO:0009968 206 0.227
Human Mouse
eye photoreceptor cell development GO:0042462 81 0.220
Fly
cellular protein localization GO:0034613 160 0.217
actin filament based process GO:0030029 220 0.216
Human Fly
regulation of developmental growth GO:0048638 174 0.216
multicellular organismal aging GO:0010259 140 0.211
protein targeting to nucleus GO:0044744 51 0.201
negative regulation of gene expression GO:0010629 387 0.196
sex differentiation GO:0007548 81 0.196
chromosome segregation GO:0007059 157 0.195
nucleus localization GO:0051647 34 0.192
regulation of hydrolase activity GO:0051336 97 0.190
eye development GO:0001654 323 0.190
regulation of response to stress GO:0080134 200 0.190
ribonucleoside catabolic process GO:0042454 112 0.190
secretion GO:0046903 109 0.189
ribonucleoside monophosphate catabolic process GO:0009158 39 0.189
establishment of protein localization to organelle GO:0072594 62 0.185
response to ketone GO:1901654 34 0.185
nuclear division GO:0000280 332 0.181
columnar cuboidal epithelial cell development GO:0002066 249 0.180
cellular response to oxidative stress GO:0034599 28 0.175
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.175
regulation of protein transport GO:0051223 57 0.174
positive regulation of protein modification process GO:0031401 58 0.170
positive regulation of cellular biosynthetic process GO:0031328 316 0.169
negative regulation of intracellular signal transduction GO:1902532 57 0.167
Human Mouse
germarium derived egg chamber formation GO:0007293 101 0.166
regulation of cellular localization GO:0060341 136 0.166
Mouse
ovarian follicle cell development GO:0030707 248 0.165
ribonucleotide catabolic process GO:0009261 109 0.164
cell fate specification GO:0001708 71 0.162
carboxylic acid metabolic process GO:0019752 92 0.160
glycosyl compound catabolic process GO:1901658 112 0.158
phosphorylation GO:0016310 294 0.157
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.152
Human
epidermal cell differentiation GO:0009913 51 0.152
secretion by cell GO:0032940 101 0.151
positive regulation of signal transduction GO:0009967 223 0.150
regulation of cellular amino acid metabolic process GO:0006521 0 0.148
amine metabolic process GO:0009308 12 0.147
cellular response to organic cyclic compound GO:0071407 32 0.147
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.146
negative regulation of response to stimulus GO:0048585 258 0.146
Human Mouse
embryonic morphogenesis GO:0048598 206 0.144
Mouse
single organism nuclear import GO:1902593 51 0.141
ribonucleoside metabolic process GO:0009119 127 0.140
positive regulation of phosphorus metabolic process GO:0010562 139 0.138
maintenance of protein location in cell GO:0032507 26 0.137
border follicle cell migration GO:0007298 113 0.134
eye photoreceptor cell fate commitment GO:0042706 37 0.133
receptor mediated endocytosis GO:0006898 21 0.130
eggshell chorion assembly GO:0007306 66 0.129
immune response GO:0006955 246 0.127
regulation of secretion GO:0051046 44 0.127
epithelial cell development GO:0002064 274 0.126
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.125
somatic muscle development GO:0007525 66 0.125
lipid metabolic process GO:0006629 121 0.124
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.123
nucleoside phosphate catabolic process GO:1901292 110 0.122
epithelial cell differentiation GO:0030855 322 0.122
Mouse
compound eye photoreceptor development GO:0042051 78 0.121
Fly
spermatid differentiation GO:0048515 114 0.121
positive regulation of cell communication GO:0010647 250 0.119
negative regulation of cell death GO:0060548 81 0.118
negative regulation of transcription dna templated GO:0045892 237 0.117
erbb signaling pathway GO:0038127 58 0.114
regulation of organelle organization GO:0033043 196 0.114
Human Fly
regulation of phosphorylation GO:0042325 147 0.111
larval development GO:0002164 104 0.111
Fly
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.109
atp catabolic process GO:0006200 38 0.109
immune system process GO:0002376 347 0.109
brain development GO:0007420 120 0.108
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 108 0.107
purine ribonucleotide catabolic process GO:0009154 109 0.107
cell cycle g1 s phase transition GO:0044843 31 0.107
autophagy GO:0006914 108 0.107
regulation of proteolysis GO:0030162 87 0.106
male meiosis cytokinesis GO:0007112 26 0.106
glycerolipid metabolic process GO:0046486 34 0.105
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.105
ubiquitin dependent protein catabolic process GO:0006511 78 0.103
Fly
cellular protein complex assembly GO:0043623 71 0.103
positive regulation of cellular amine metabolic process GO:0033240 0 0.103
organic substance transport GO:0071702 257 0.103
regulation of cell cycle phase transition GO:1901987 130 0.103
maintenance of location in cell GO:0051651 28 0.101
proteolysis GO:0006508 192 0.100
Fly
positive regulation of protein phosphorylation GO:0001934 34 0.099
negative regulation of cellular metabolic process GO:0031324 382 0.098
Human Mouse
learning or memory GO:0007611 141 0.097
cellular response to organonitrogen compound GO:0071417 36 0.097
tissue morphogenesis GO:0048729 297 0.097
Mouse Fly
organelle localization GO:0051640 148 0.097
Fly
protein catabolic process GO:0030163 101 0.096
Fly
programmed cell death GO:0012501 257 0.095
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.095
regulation of programmed cell death GO:0043067 152 0.095
immune system development GO:0002520 57 0.094
death GO:0016265 284 0.094
positive regulation of transcription dna templated GO:0045893 266 0.093
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.091
cellular amino acid metabolic process GO:0006520 61 0.090
imaginal disc derived wing vein specification GO:0007474 48 0.090
cellular response to endogenous stimulus GO:0071495 80 0.088
cellular protein modification process GO:0006464 438 0.087
oxoacid metabolic process GO:0043436 103 0.087
nuclear import GO:0051170 51 0.087
positive regulation of response to stimulus GO:0048584 323 0.087
carbohydrate derivative catabolic process GO:1901136 118 0.086
regulation of embryonic development GO:0045995 68 0.086
regulation of protein localization GO:0032880 76 0.085
Mouse
sensory perception GO:0007600 196 0.085
ribonucleoside triphosphate catabolic process GO:0009203 108 0.085
regulation of cell morphogenesis GO:0022604 163 0.084
regulation of cellular response to stress GO:0080135 89 0.084
skin development GO:0043588 65 0.083
female germ line cyst formation GO:0048135 42 0.083
negative regulation of developmental process GO:0051093 201 0.081
positive regulation of signaling GO:0023056 243 0.080
g1 s transition of mitotic cell cycle GO:0000082 31 0.079
organophosphate catabolic process GO:0046434 112 0.079
regulation of anatomical structure size GO:0090066 163 0.079
connective tissue development GO:0061448 3 0.078
morphogenesis of a branching epithelium GO:0061138 45 0.078
positive regulation of proteolysis GO:0045862 52 0.078
wing disc morphogenesis GO:0007472 344 0.078
positive regulation of rho gtpase activity GO:0032321 19 0.078
ribonucleoside triphosphate metabolic process GO:0009199 119 0.077
localization of cell GO:0051674 257 0.075
nucleoside catabolic process GO:0009164 112 0.074
exocrine system development GO:0035272 162 0.073
positive regulation of nucleic acid templated transcription GO:1903508 266 0.072
body morphogenesis GO:0010171 2 0.072
dna metabolic process GO:0006259 227 0.071
Human
regulation of organ morphogenesis GO:2000027 78 0.070
compound eye morphogenesis GO:0001745 249 0.070
mitotic spindle organization GO:0007052 220 0.070
Fly
organophosphate metabolic process GO:0019637 195 0.068
regulation of erbb signaling pathway GO:1901184 42 0.068
regulation of protein phosphorylation GO:0001932 64 0.068
positive regulation of biosynthetic process GO:0009891 316 0.068
organonitrogen compound catabolic process GO:1901565 128 0.068
open tracheal system development GO:0007424 204 0.068
negative regulation of molecular function GO:0044092 51 0.068
Mouse
modification dependent macromolecule catabolic process GO:0043632 79 0.067
Fly
cell division GO:0051301 248 0.067
negative regulation of rna metabolic process GO:0051253 251 0.067
growth GO:0040007 359 0.066
regulation of protein modification process GO:0031399 112 0.064
positive regulation of programmed cell death GO:0043068 62 0.063
regulation of cellular response to hypoxia GO:1900037 3 0.062
negative regulation of mitotic cell cycle GO:0045930 109 0.062
spermatid development GO:0007286 98 0.061
regulation of molecular function GO:0065009 217 0.060
Mouse
response to organonitrogen compound GO:0010243 75 0.060
positive regulation of transport GO:0051050 92 0.060
Fly
developmental growth GO:0048589 280 0.059
organonitrogen compound metabolic process GO:1901564 318 0.058
negative regulation of cell differentiation GO:0045596 143 0.057
regulation of ras gtpase activity GO:0032318 38 0.057
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.056
epidermal growth factor receptor signaling pathway GO:0007173 58 0.056
cellular component disassembly GO:0022411 46 0.056
appendage morphogenesis GO:0035107 397 0.056
organic substance catabolic process GO:1901575 308 0.056
Fly
positive regulation of organelle organization GO:0010638 65 0.056
Human
spindle assembly GO:0051225 80 0.054
single organism biosynthetic process GO:0044711 206 0.054
cell junction organization GO:0034330 57 0.054
Mouse
mitotic sister chromatid segregation GO:0000070 87 0.054
Fly
male meiosis GO:0007140 52 0.053
long term memory GO:0007616 62 0.053
regulation of intracellular transport GO:0032386 64 0.053
response to heat GO:0009408 63 0.052
germ line cyst formation GO:0048134 44 0.052
regulation of cell shape GO:0008360 113 0.051
protein ubiquitination GO:0016567 70 0.051
neuron fate commitment GO:0048663 50 0.051
vesicle mediated transport GO:0016192 381 0.050
gland development GO:0048732 191 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.050
regulation of rho gtpase activity GO:0032319 20 0.050
negative regulation of cell cycle process GO:0010948 109 0.049
negative regulation of programmed cell death GO:0043069 72 0.049
oocyte construction GO:0007308 112 0.049
purine ribonucleoside metabolic process GO:0046128 127 0.049
regulation of mitotic cell cycle phase transition GO:1901990 130 0.048
nucleotide metabolic process GO:0009117 161 0.048
negative regulation of nucleic acid templated transcription GO:1903507 240 0.047
reproductive structure development GO:0048608 74 0.047
single organism intracellular transport GO:1902582 207 0.047
regulation of neural precursor cell proliferation GO:2000177 35 0.047
Mouse
negative regulation of developmental growth GO:0048640 64 0.046
regulation of nucleocytoplasmic transport GO:0046822 35 0.046
cell migration GO:0016477 238 0.046
protein modification process GO:0036211 438 0.045
positive regulation of gtpase activity GO:0043547 43 0.045
regulation of protein import into nucleus GO:0042306 28 0.045
response to nitrogen compound GO:1901698 90 0.044
pigmentation GO:0043473 75 0.044
cell motility GO:0048870 251 0.044
regulation of chromatin modification GO:1903308 28 0.043
dna packaging GO:0006323 91 0.043
nuclear body organization GO:0030575 6 0.043
purine nucleoside monophosphate metabolic process GO:0009126 50 0.043
regulation of intracellular protein transport GO:0033157 46 0.043
regulation of microtubule cytoskeleton organization GO:0070507 41 0.043
axon development GO:0061564 297 0.042
Fly
regulation of secretion by cell GO:1903530 39 0.042
digestive tract development GO:0048565 149 0.041
Mouse
maintenance of location GO:0051235 73 0.041
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.041
negative regulation of phosphorus metabolic process GO:0010563 45 0.041
Human Mouse
response to lipid GO:0033993 38 0.040
signal transduction by phosphorylation GO:0023014 107 0.039
Mouse
cellular response to carbohydrate stimulus GO:0071322 4 0.039
photoreceptor cell differentiation GO:0046530 170 0.039
response to hexose GO:0009746 3 0.039
cytoplasmic transport GO:0016482 130 0.039
regulation of gtpase activity GO:0043087 44 0.039
imaginal disc derived leg morphogenesis GO:0007480 80 0.038
regulation of nervous system development GO:0051960 248 0.038
nucleotide catabolic process GO:0009166 109 0.038
regulation of catabolic process GO:0009894 170 0.038
negative regulation of cellular biosynthetic process GO:0031327 277 0.037
Human
purine containing compound catabolic process GO:0072523 112 0.037
negative regulation of cell development GO:0010721 62 0.037
regulation of imaginal disc growth GO:0045570 26 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.037
Fly
regulation of nucleotide catabolic process GO:0030811 48 0.037
positive regulation of phosphorylation GO:0042327 87 0.037
regulation of nucleotide metabolic process GO:0006140 62 0.036
spindle elongation GO:0051231 83 0.036
epithelial tube morphogenesis GO:0060562 88 0.035
mapk cascade GO:0000165 107 0.035
Mouse
negative regulation of mapk cascade GO:0043409 23 0.034
Mouse
regulation of cell cycle g1 s phase transition GO:1902806 23 0.034
negative regulation of cell cycle phase transition GO:1901988 103 0.034
response to endogenous stimulus GO:0009719 119 0.034
hemopoiesis GO:0030097 46 0.034
morphogenesis of a branching structure GO:0001763 45 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.034
Human
positive regulation of intracellular protein transport GO:0090316 30 0.033
eggshell formation GO:0030703 105 0.033
tube development GO:0035295 244 0.033
Mouse
response to organic cyclic compound GO:0014070 89 0.033
cell proliferation GO:0008283 299 0.033
establishment of ommatidial planar polarity GO:0042067 49 0.033
positive regulation of cell migration GO:0030335 2 0.033
response to glucose GO:0009749 2 0.033
protein complex disassembly GO:0043241 36 0.032
morphogenesis of an epithelium GO:0002009 276 0.032
Fly
proteasomal protein catabolic process GO:0010498 59 0.032
Fly
regulation of establishment of protein localization GO:0070201 61 0.032
small gtpase mediated signal transduction GO:0007264 88 0.032
regulation of cell differentiation GO:0045595 302 0.031
positive regulation of protein import into nucleus GO:0042307 21 0.031
organ growth GO:0035265 56 0.031
development of primary sexual characteristics GO:0045137 50 0.030
positive regulation of cell motility GO:2000147 3 0.030
regulation of cell cycle process GO:0010564 181 0.030
Fly
genitalia development GO:0048806 26 0.030
stem cell development GO:0048864 79 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
positive regulation of nucleotide metabolic process GO:0045981 55 0.029
negative regulation of nervous system development GO:0051961 92 0.028
regulation of protein localization to nucleus GO:1900180 29 0.028
Mouse
histolysis GO:0007559 102 0.028
peptidyl amino acid modification GO:0018193 105 0.027
Human
salivary gland development GO:0007431 162 0.027
regulation of cytokinesis GO:0032465 3 0.027
response to ionizing radiation GO:0010212 32 0.027
dorsal closure GO:0007391 79 0.027
salivary gland histolysis GO:0035070 88 0.027
head development GO:0060322 135 0.027
Mouse
dosage compensation GO:0007549 16 0.027
apoptotic process GO:0006915 159 0.026
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.026
compound eye photoreceptor fate commitment GO:0001752 36 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
Fly
cellular macromolecular complex assembly GO:0034622 153 0.025
nuclear transport GO:0051169 72 0.025
gtp catabolic process GO:0006184 72 0.025
modification dependent protein catabolic process GO:0019941 78 0.025
Fly
dna conformation change GO:0071103 105 0.024
positive regulation of autophagy GO:0010508 21 0.024
axis specification GO:0009798 167 0.023
microtubule anchoring GO:0034453 11 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
response to sterol GO:0036314 34 0.023
meiosis ii GO:0007135 23 0.023
dephosphorylation GO:0016311 51 0.023
ras protein signal transduction GO:0007265 88 0.022
cellular protein catabolic process GO:0044257 83 0.022
Fly
cellular response to radiation GO:0071478 52 0.022
macromolecule methylation GO:0043414 45 0.022
regulation of ras protein signal transduction GO:0046578 93 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.022
cellular chemical homeostasis GO:0055082 40 0.022
regulation of rho protein signal transduction GO:0035023 20 0.022
organelle fission GO:0048285 340 0.022
regulation of chromatin organization GO:1902275 32 0.022
stress activated mapk cascade GO:0051403 52 0.021
protein polymerization GO:0051258 42 0.021
cellular protein complex disassembly GO:0043624 35 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
response to hydrogen peroxide GO:0042542 11 0.021
peptide hormone secretion GO:0030072 5 0.021
positive regulation of protein localization to nucleus GO:1900182 21 0.021
developmental programmed cell death GO:0010623 138 0.021
gland morphogenesis GO:0022612 145 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
regulation of proteasomal protein catabolic process GO:0061136 39 0.020
protein maturation GO:0051604 71 0.020
dorsal ventral axis specification GO:0009950 66 0.020
positive regulation of endopeptidase activity GO:0010950 26 0.020
positive regulation of nucleotide catabolic process GO:0030813 46 0.019
meiotic cytokinesis GO:0033206 33 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
sister chromatid segregation GO:0000819 92 0.019
Fly
innate immune response GO:0045087 144 0.019
establishment of mitotic spindle orientation GO:0000132 13 0.019
Fly
necrotic cell death GO:0070265 1 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
Human
regulation of cell fate commitment GO:0010453 29 0.019
hormone secretion GO:0046879 7 0.019
cytoskeleton dependent cytokinesis GO:0061640 81 0.019
single organism catabolic process GO:0044712 228 0.019
Fly
wnt signaling pathway GO:0016055 98 0.019
cognition GO:0050890 141 0.018
cellular response to nitrogen compound GO:1901699 51 0.018
nucleoside monophosphate metabolic process GO:0009123 52 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.018
regulation of cell fate specification GO:0042659 27 0.018
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.018
regulation of kinase activity GO:0043549 53 0.017
Mouse
morphogenesis of an epithelial bud GO:0060572 3 0.017
regulation of insulin like growth factor receptor signaling pathway GO:0043567 3 0.017
nucleocytoplasmic transport GO:0006913 72 0.017
cell activation GO:0001775 9 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
regulation of transport GO:0051049 181 0.017
Fly
positive regulation of ras gtpase activity GO:0032320 36 0.017
negative regulation of glial cell proliferation GO:0060253 6 0.017
positive regulation of gene expression GO:0010628 290 0.017
positive regulation of mitotic cell cycle GO:0045931 34 0.016
autophagic cell death GO:0048102 83 0.016
negative regulation of imaginal disc growth GO:0045571 8 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.016
regulation of apoptotic process GO:0042981 130 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
response to growth factor GO:0070848 31 0.016
response to transforming growth factor beta GO:0071559 18 0.015
attachment of spindle microtubules to kinetochore GO:0008608 5 0.015
metal ion transport GO:0030001 74 0.015
regulation of chromosome organization GO:0033044 64 0.015
Fly
regulation of purine nucleotide catabolic process GO:0033121 48 0.015
mitotic cell cycle embryonic GO:0045448 38 0.015
positive regulation of cell cycle GO:0045787 43 0.015
macromolecular complex disassembly GO:0032984 37 0.015
negative regulation of insulin secretion GO:0046676 1 0.015
reproductive system development GO:0061458 74 0.015
negative regulation of protein maturation GO:1903318 31 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
branching morphogenesis of an epithelial tube GO:0048754 45 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.015
dorsal appendage formation GO:0046843 47 0.015
positive regulation of cell differentiation GO:0045597 64 0.015
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
double strand break repair GO:0006302 26 0.015

Mer disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.019
disease of anatomical entity DOID:7 0 0.019
eye and adnexa disease DOID:1492 0 0.019
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.019
Human
disease of cellular proliferation DOID:14566 0 0.019
Human
organ system cancer DOID:0050686 0 0.019
Human
cardiovascular system disease DOID:1287 0 0.018