Drosophila melanogaster

0 known processes

Map60 (Dmel_CG1825)

Microtubule-associated protein 60

(Aliases: CP60,DMAP-60,Dmel\CG1825,CG1825,DMAP60,Cp60,CP-60)

Map60 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.760
transcription from rna polymerase ii promoter GO:0006366 368 0.738
positive regulation of macromolecule metabolic process GO:0010604 405 0.687
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.655
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.558
positive regulation of cellular biosynthetic process GO:0031328 316 0.537
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.509
positive regulation of biosynthetic process GO:0009891 316 0.467
mitotic nuclear division GO:0007067 213 0.440
negative regulation of rna metabolic process GO:0051253 251 0.398
regulation of cell differentiation GO:0045595 302 0.344
chromatin organization GO:0006325 207 0.343
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.342
dna conformation change GO:0071103 105 0.322
positive regulation of nucleic acid templated transcription GO:1903508 266 0.321
intracellular signal transduction GO:0035556 300 0.310
positive regulation of rna metabolic process GO:0051254 271 0.302
positive regulation of rna biosynthetic process GO:1902680 266 0.293
cell death GO:0008219 279 0.292
positive regulation of transcription dna templated GO:0045893 266 0.288
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.285
organelle fission GO:0048285 340 0.272
positive regulation of gene expression GO:0010628 290 0.253
regulation of molecular function GO:0065009 217 0.204
positive regulation of cellular protein metabolic process GO:0032270 118 0.175
regulation of cellular protein metabolic process GO:0032268 243 0.168
negative regulation of nucleic acid templated transcription GO:1903507 240 0.166
negative regulation of transcription dna templated GO:0045892 237 0.164
establishment of localization in cell GO:0051649 402 0.161
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.160
regulation of programmed cell death GO:0043067 152 0.150
intracellular transport GO:0046907 228 0.142
regulation of protein metabolic process GO:0051246 256 0.142
central nervous system development GO:0007417 201 0.135
regulation of cell death GO:0010941 173 0.134
mitotic spindle organization GO:0007052 220 0.126
negative regulation of biosynthetic process GO:0009890 277 0.123
regulation of phosphate metabolic process GO:0019220 210 0.119
nuclear division GO:0000280 332 0.118
regulation of hydrolase activity GO:0051336 97 0.117
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.113
spindle organization GO:0007051 253 0.109
spindle assembly GO:0051225 80 0.107
negative regulation of gene expression GO:0010629 387 0.106
death GO:0016265 284 0.105
regulation of cell cycle process GO:0010564 181 0.104
catabolic process GO:0009056 409 0.095
regulation of cellular component biogenesis GO:0044087 201 0.089
immune system process GO:0002376 347 0.089
protein localization GO:0008104 284 0.087
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.087
regulation of cellular catabolic process GO:0031329 157 0.087
regulation of mitosis GO:0007088 56 0.086
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.082
positive regulation of molecular function GO:0044093 136 0.081
negative regulation of cellular metabolic process GO:0031324 382 0.078
negative regulation of developmental process GO:0051093 201 0.077
regulation of phosphorylation GO:0042325 147 0.076
chromatin modification GO:0016568 147 0.076
regulation of mitotic cell cycle phase transition GO:1901990 130 0.075
regulation of phosphorus metabolic process GO:0051174 210 0.075
phosphorylation GO:0016310 294 0.075
spindle assembly involved in mitosis GO:0090307 50 0.074
cellular response to dna damage stimulus GO:0006974 223 0.074
negative regulation of rna biosynthetic process GO:1902679 240 0.074
regulation of cell cycle GO:0051726 291 0.073
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.073
dendrite development GO:0016358 204 0.070
negative regulation of cell differentiation GO:0045596 143 0.070
regulation of catalytic activity GO:0050790 185 0.070
nuclear transport GO:0051169 72 0.069
protein modification process GO:0036211 438 0.068
cellular catabolic process GO:0044248 372 0.066
response to biotic stimulus GO:0009607 294 0.066
aging GO:0007568 143 0.065
protein dna complex assembly GO:0065004 63 0.063
protein complex biogenesis GO:0070271 201 0.062
ubiquitin dependent protein catabolic process GO:0006511 78 0.060
positive regulation of phosphate metabolic process GO:0045937 139 0.058
organic substance transport GO:0071702 257 0.058
embryo development ending in birth or egg hatching GO:0009792 152 0.055
covalent chromatin modification GO:0016569 106 0.055
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.055
sister chromatid segregation GO:0000819 92 0.055
mitotic sister chromatid segregation GO:0000070 87 0.055
appendage morphogenesis GO:0035107 397 0.054
positive regulation of response to stimulus GO:0048584 323 0.054
regulation of apoptotic process GO:0042981 130 0.053
regulation of proteolysis GO:0030162 87 0.052
response to other organism GO:0051707 293 0.052
proteolysis GO:0006508 192 0.052
organonitrogen compound metabolic process GO:1901564 318 0.051
neuroblast proliferation GO:0007405 74 0.051
cell proliferation GO:0008283 299 0.050
positive regulation of protein metabolic process GO:0051247 128 0.049
g1 s transition of mitotic cell cycle GO:0000082 31 0.049
centrosome organization GO:0051297 163 0.049
regulation of catabolic process GO:0009894 170 0.047
cell division GO:0051301 248 0.047
chromosome segregation GO:0007059 157 0.046
regulation of response to stress GO:0080134 200 0.045
regulation of mitotic cell cycle GO:0007346 190 0.045
intracellular protein transport GO:0006886 104 0.045
negative regulation of response to stimulus GO:0048585 258 0.044
response to organic substance GO:0010033 284 0.043
regulation of multicellular organismal development GO:2000026 414 0.042
programmed cell death GO:0012501 257 0.042
positive regulation of phosphorus metabolic process GO:0010562 139 0.041
mitotic sister chromatid separation GO:0051306 30 0.041
dendrite morphogenesis GO:0048813 199 0.041
cellularization GO:0007349 90 0.040
mrna metabolic process GO:0016071 124 0.040
positive regulation of signal transduction GO:0009967 223 0.040
dna metabolic process GO:0006259 227 0.039
stem cell differentiation GO:0048863 117 0.039
stem cell maintenance GO:0019827 67 0.039
ras protein signal transduction GO:0007265 88 0.039
positive regulation of developmental process GO:0051094 143 0.038
negative regulation of cell cycle GO:0045786 116 0.038
mrna processing GO:0006397 104 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
regulation of immune system process GO:0002682 176 0.037
epithelial cell differentiation GO:0030855 322 0.037
positive regulation of hydrolase activity GO:0051345 78 0.037
single organism catabolic process GO:0044712 228 0.036
protein processing GO:0016485 68 0.036
cell cycle dna replication GO:0044786 23 0.036
regulation of cellular localization GO:0060341 136 0.036
regulation of cell cycle phase transition GO:1901987 130 0.036
regulation of dna recombination GO:0000018 4 0.035
mitotic cell cycle phase transition GO:0044772 138 0.035
cellular protein modification process GO:0006464 438 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
organic substance catabolic process GO:1901575 308 0.034
purine containing compound catabolic process GO:0072523 112 0.034
negative regulation of cell communication GO:0010648 223 0.033
protein transport GO:0015031 155 0.033
actin filament organization GO:0007015 126 0.033
negative regulation of molecular function GO:0044092 51 0.033
cellular protein catabolic process GO:0044257 83 0.032
muscle organ development GO:0007517 127 0.032
camera type eye development GO:0043010 4 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
positive regulation of phosphorylation GO:0042327 87 0.032
regulation of intracellular signal transduction GO:1902531 236 0.032
positive regulation of mitotic cell cycle GO:0045931 34 0.031
protein phosphorylation GO:0006468 169 0.031
eye morphogenesis GO:0048592 260 0.031
nucleoside phosphate catabolic process GO:1901292 110 0.031
modification dependent protein catabolic process GO:0019941 78 0.031
negative regulation of cell cycle process GO:0010948 109 0.030
macromolecule catabolic process GO:0009057 161 0.030
establishment or maintenance of cell polarity GO:0007163 167 0.029
cell cycle g1 s phase transition GO:0044843 31 0.028
negative regulation of signaling GO:0023057 219 0.028
immune response GO:0006955 246 0.028
open tracheal system development GO:0007424 204 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.027
germ line stem cell maintenance GO:0030718 50 0.027
dephosphorylation GO:0016311 51 0.027
negative regulation of meiotic cell cycle GO:0051447 2 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.026
cellular macromolecule localization GO:0070727 220 0.026
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.026
regulation of protein catabolic process GO:0042176 55 0.026
response to oxidative stress GO:0006979 86 0.025
eye development GO:0001654 323 0.025
negative regulation of organelle organization GO:0010639 56 0.025
response to external biotic stimulus GO:0043207 293 0.024
regionalization GO:0003002 416 0.024
small molecule metabolic process GO:0044281 305 0.024
regulation of proteasomal protein catabolic process GO:0061136 39 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
macromolecular complex assembly GO:0065003 256 0.024
positive regulation of protein modification process GO:0031401 58 0.024
cellular response to chemical stimulus GO:0070887 199 0.023
compound eye development GO:0048749 307 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
respiratory system development GO:0060541 213 0.022
terminal button organization GO:0072553 19 0.022
regulation of cell cycle g1 s phase transition GO:1902806 23 0.022
rna processing GO:0006396 147 0.022
mitotic cytokinesis GO:0000281 50 0.022
negative regulation of mitotic cell cycle GO:0045930 109 0.022
camera type eye morphogenesis GO:0048593 2 0.022
regulation of cytoplasmic transport GO:1903649 47 0.022
negative regulation of protein processing GO:0010955 31 0.022
protein targeting GO:0006605 64 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.022
protein maturation GO:0051604 71 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
single organism intracellular transport GO:1902582 207 0.021
stem cell development GO:0048864 79 0.021
circulatory system development GO:0072359 82 0.021
chromosome separation GO:0051304 42 0.020
regulation of gene expression epigenetic GO:0040029 128 0.020
protein catabolic process GO:0030163 101 0.020
response to abiotic stimulus GO:0009628 341 0.020
protein complex assembly GO:0006461 200 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
regulation of transport GO:0051049 181 0.019
positive regulation of cell communication GO:0010647 250 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of nucleocytoplasmic transport GO:0046822 35 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
nucleoside catabolic process GO:0009164 112 0.019
retina development in camera type eye GO:0060041 4 0.019
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.019
regulation of cell development GO:0060284 215 0.019
regulation of chromosome organization GO:0033044 64 0.019
regulation of intracellular transport GO:0032386 64 0.019
chaeta development GO:0022416 97 0.019
regulation of localization GO:0032879 275 0.019
heart contraction GO:0060047 26 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
cytokinesis GO:0000910 90 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
negative regulation of proteolysis GO:0045861 31 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.018
nucleotide metabolic process GO:0009117 161 0.018
nuclear dna replication GO:0033260 1 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
developmental maturation GO:0021700 172 0.018
organelle assembly GO:0070925 198 0.018
nuclear import GO:0051170 51 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
regulation of protein modification process GO:0031399 112 0.018
cell migration GO:0016477 238 0.018
positive regulation of rho protein signal transduction GO:0035025 4 0.017
negative regulation of signal transduction GO:0009968 206 0.017
cystoblast division GO:0007282 10 0.017
positive regulation of cell cycle process GO:0090068 28 0.017
dna packaging GO:0006323 91 0.017
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.017
cytoplasmic transport GO:0016482 130 0.017
regulation of cell proliferation GO:0042127 163 0.017
meiotic cell cycle process GO:1903046 132 0.017
ribonucleoside catabolic process GO:0042454 112 0.016
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
neuronal stem cell division GO:0036445 35 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
regulation of organelle organization GO:0033043 196 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
spinal cord development GO:0021510 1 0.016
synapse organization GO:0050808 196 0.016
tube development GO:0035295 244 0.016
response to endogenous stimulus GO:0009719 119 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
nucleoside monophosphate metabolic process GO:0009123 52 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
negative regulation of cell death GO:0060548 81 0.015
hematopoietic or lymphoid organ development GO:0048534 57 0.015
sensory organ morphogenesis GO:0090596 260 0.015
stem cell proliferation GO:0072089 88 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
mrna cis splicing via spliceosome GO:0045292 1 0.015
regulation of cell shape GO:0008360 113 0.015
positive regulation of gtpase activity GO:0043547 43 0.015
female germ line cyst formation GO:0048135 42 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
positive regulation of immune system process GO:0002684 68 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
homeostatic process GO:0042592 199 0.014
positive regulation of catabolic process GO:0009896 105 0.014
single organism biosynthetic process GO:0044711 206 0.014
oocyte development GO:0048599 124 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
regulation of protein processing GO:0070613 32 0.014
regulation of protein phosphorylation GO:0001932 64 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
purine containing compound metabolic process GO:0072521 155 0.013
vesicle mediated transport GO:0016192 381 0.013
metaphase anaphase transition of cell cycle GO:0044784 28 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
positive regulation of neuron projection regeneration GO:0070572 3 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
multicellular organismal aging GO:0010259 140 0.013
regulation of multi organism process GO:0043900 131 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
glial cell migration GO:0008347 31 0.013
regulation of transcription by chromatin organization GO:0034401 3 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
tissue migration GO:0090130 155 0.013
histone methylation GO:0016571 40 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
apoptotic process GO:0006915 159 0.012
atp catabolic process GO:0006200 38 0.012
cellular protein localization GO:0034613 160 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
positive regulation of organelle organization GO:0010638 65 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
establishment of protein localization GO:0045184 163 0.012
protein alkylation GO:0008213 43 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
rna localization GO:0006403 115 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
dna duplex unwinding GO:0032508 16 0.012
histone modification GO:0016570 106 0.012
positive regulation of intracellular transport GO:0032388 42 0.012
embryonic organ development GO:0048568 50 0.012
somatic stem cell division GO:0048103 37 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
larval development GO:0002164 104 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
endocytosis GO:0006897 310 0.011
nucleosome assembly GO:0006334 35 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
male gamete generation GO:0048232 201 0.011
cell cycle checkpoint GO:0000075 95 0.011
nitrogen compound transport GO:0071705 85 0.011
regulation of double strand break repair GO:2000779 3 0.011
body morphogenesis GO:0010171 2 0.011
protein localization to nucleus GO:0034504 55 0.011
aromatic compound catabolic process GO:0019439 166 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
heart development GO:0007507 82 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
wing disc morphogenesis GO:0007472 344 0.011
single organism behavior GO:0044708 391 0.011
oocyte differentiation GO:0009994 145 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
phagocytosis GO:0006909 215 0.011
regulation of rac gtpase activity GO:0032314 1 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
maintenance of location GO:0051235 73 0.010
positive regulation of cell cycle GO:0045787 43 0.010
mitochondrial membrane organization GO:0007006 3 0.010
protein import into nucleus GO:0006606 51 0.010
single organism cellular localization GO:1902580 180 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
ion transport GO:0006811 145 0.010
asymmetric stem cell division GO:0098722 49 0.010
regulation of cell division GO:0051302 72 0.010

Map60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014