Drosophila melanogaster

36 known processes

cyc (Dmel_CG8727)

cycle

(Aliases: Bmal1,CG8727,CYC,dCYC,Cyc,dBma1,dbmal,dBMAL1,dBmal,dBMAL,bmal1,MOP3,BMAL1,Dmel\CG8727,bMAL1,bHLHe7,Mop3,Cycle,dbmal1,CYCLE)

cyc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rhythmic process GO:0048511 106 0.998
circadian behavior GO:0048512 76 0.998
circadian rhythm GO:0007623 105 0.987
regulation of circadian rhythm GO:0042752 49 0.936
single organism behavior GO:0044708 391 0.933
rhythmic behavior GO:0007622 76 0.895
locomotory behavior GO:0007626 176 0.814
circadian sleep wake cycle sleep GO:0050802 23 0.509
locomotor rhythm GO:0045475 56 0.465
circadian sleep wake cycle process GO:0022410 24 0.232
negative regulation of rna metabolic process GO:0051253 251 0.221
Zebrafish Mouse Fly
chromatin modification GO:0016568 147 0.208
organelle fission GO:0048285 340 0.185
sleep GO:0030431 49 0.182
protein acetylation GO:0006473 39 0.178
negative regulation of gene expression GO:0010629 387 0.172
Zebrafish Mouse Fly
response to light stimulus GO:0009416 124 0.151
Zebrafish
response to radiation GO:0009314 155 0.149
Zebrafish
dna metabolic process GO:0006259 227 0.140
negative regulation of transcription dna templated GO:0045892 237 0.138
Zebrafish Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.130
Human Mouse Fly
histone acetylation GO:0016573 38 0.129
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.123
Zebrafish Mouse Fly
circadian sleep wake cycle GO:0042745 28 0.123
peptidyl lysine acetylation GO:0018394 39 0.123
regulation of behavior GO:0050795 75 0.112
transcription from rna polymerase ii promoter GO:0006366 368 0.106
Human Mouse Fly
mitotic cell cycle phase transition GO:0044772 138 0.102
protein modification process GO:0036211 438 0.102
chromatin organization GO:0006325 207 0.100
gene silencing GO:0016458 138 0.098
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.097
dna integrity checkpoint GO:0031570 81 0.086
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.086
Zebrafish Mouse Fly
cell cycle checkpoint GO:0000075 95 0.076
regulation of circadian sleep wake cycle GO:0042749 25 0.070
male gamete generation GO:0048232 201 0.067
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.066
Human Zebrafish Mouse Rat Fly
epithelial cell differentiation GO:0030855 322 0.063
Mouse
negative regulation of cell communication GO:0010648 223 0.062
Mouse
olfactory learning GO:0008355 56 0.061
nuclear division GO:0000280 332 0.060
meiotic cell cycle GO:0051321 171 0.059
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.059
Zebrafish Mouse Fly
multi organism behavior GO:0051705 175 0.059
negative regulation of cellular biosynthetic process GO:0031327 277 0.056
Zebrafish Mouse Fly
negative regulation of signal transduction GO:0009968 206 0.056
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.055
Human Zebrafish Mouse Rat Fly
meiotic nuclear division GO:0007126 151 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.052
Zebrafish Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
Human Zebrafish Mouse Rat Fly
response to temperature stimulus GO:0009266 106 0.048
chromosome organization GO:0051276 360 0.046
cellular response to dna damage stimulus GO:0006974 223 0.045
taxis GO:0042330 304 0.045
peptidyl lysine modification GO:0018205 57 0.045
positive regulation of behavior GO:0048520 19 0.044
meiotic cell cycle process GO:1903046 132 0.043
protein dna complex subunit organization GO:0071824 86 0.043
muscle organ development GO:0007517 127 0.042
Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.042
Zebrafish Mouse Fly
cellular protein modification process GO:0006464 438 0.038
learning or memory GO:0007611 141 0.038
spermatogenesis GO:0007283 200 0.038
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.037
Zebrafish Mouse Fly
regulation of intracellular signal transduction GO:1902531 236 0.037
Mouse
response to organophosphorus GO:0046683 2 0.037
regulation of phosphorylation GO:0042325 147 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
Zebrafish Mouse Fly
positive regulation of defense response GO:0031349 59 0.035
regulation of mitotic cell cycle GO:0007346 190 0.033
posttranscriptional gene silencing GO:0016441 46 0.032
gene silencing by rna GO:0031047 57 0.031
response to abiotic stimulus GO:0009628 341 0.031
Zebrafish Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.031
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.030
Zebrafish Mouse Fly
regulation of cell cycle GO:0051726 291 0.030
Mouse
photoperiodism GO:0009648 10 0.030
Zebrafish
developmental maturation GO:0021700 172 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
Human Zebrafish Mouse Rat Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.029
Human Zebrafish Mouse Rat Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
Human Mouse Fly
covalent chromatin modification GO:0016569 106 0.028
cognition GO:0050890 141 0.028
determination of adult lifespan GO:0008340 137 0.027
regulation of defense response GO:0031347 102 0.027
mitotic nuclear division GO:0007067 213 0.026
positive regulation of rna metabolic process GO:0051254 271 0.025
Human Zebrafish Mouse Rat Fly
internal protein amino acid acetylation GO:0006475 38 0.025
entrainment of circadian clock GO:0009649 16 0.024
internal peptidyl lysine acetylation GO:0018393 38 0.024
cellular catabolic process GO:0044248 372 0.024
Mouse
neuroblast division GO:0055057 35 0.024
negative regulation of cell death GO:0060548 81 0.024
oocyte differentiation GO:0009994 145 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
Zebrafish Mouse Fly
negative regulation of signaling GO:0023057 219 0.024
Mouse
neurological system process GO:0050877 358 0.023
macromolecule catabolic process GO:0009057 161 0.023
Mouse
appendage morphogenesis GO:0035107 397 0.022
response to nutrient levels GO:0031667 114 0.022
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
Human Zebrafish Mouse Rat Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
Human Zebrafish Mouse Rat Fly
response to bacterium GO:0009617 198 0.021
regulation of cellular response to stress GO:0080135 89 0.021
Mouse
response to oxygen containing compound GO:1901700 200 0.021
Fly
peptidyl amino acid modification GO:0018193 105 0.021
adult locomotory behavior GO:0008344 76 0.020
regulation of epithelial cell differentiation GO:0030856 4 0.020
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.020
cell cycle phase transition GO:0044770 140 0.019
intracellular receptor signaling pathway GO:0030522 19 0.019
Mouse
learning GO:0007612 75 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
peptidyl threonine phosphorylation GO:0018107 2 0.019
dna repair GO:0006281 54 0.019
asymmetric stem cell division GO:0098722 49 0.018
secretion GO:0046903 109 0.018
Mouse
defense response to gram negative bacterium GO:0050829 94 0.018
cell maturation GO:0048469 144 0.018
oocyte axis specification GO:0007309 108 0.017
camera type eye development GO:0043010 4 0.017
endocytosis GO:0006897 310 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
positive regulation of gene expression GO:0010628 290 0.017
Human Zebrafish Mouse Rat Fly
histone modification GO:0016570 106 0.017
detection of external stimulus GO:0009581 66 0.017
catabolic process GO:0009056 409 0.017
Mouse
muscle structure development GO:0061061 224 0.017
Mouse Fly
phagocytosis GO:0006909 215 0.017
rna interference GO:0016246 27 0.017
protein catabolic process GO:0030163 101 0.016
Mouse
detection of abiotic stimulus GO:0009582 66 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
Mouse
ubiquitin dependent protein catabolic process GO:0006511 78 0.016
Mouse
regulation of localization GO:0032879 275 0.016
Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.016
positive regulation of response to external stimulus GO:0032103 44 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
Mouse
male mating behavior GO:0060179 70 0.016
vesicle mediated transport GO:0016192 381 0.016
organic substance catabolic process GO:1901575 308 0.016
Mouse
associative learning GO:0008306 65 0.016
modification dependent protein catabolic process GO:0019941 78 0.015
Mouse
rna processing GO:0006396 147 0.015
phototransduction GO:0007602 52 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
Mouse
detection of stimulus GO:0051606 156 0.015
cellular homeostasis GO:0019725 80 0.015
positive regulation of apoptotic signaling pathway GO:2001235 4 0.015
nucleoside phosphate biosynthetic process GO:1901293 34 0.015
protein complex assembly GO:0006461 200 0.014
negative regulation of homeostatic process GO:0032845 2 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
response to organic substance GO:0010033 284 0.014
Fly
immune response activating signal transduction GO:0002757 2 0.014
single organism biosynthetic process GO:0044711 206 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
heart contraction GO:0060047 26 0.014
rna splicing via transesterification reactions GO:0000375 73 0.014
ion transport GO:0006811 145 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
regulation of mapk cascade GO:0043408 92 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
trna modification GO:0006400 2 0.013
axon development GO:0061564 297 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
cellular protein catabolic process GO:0044257 83 0.013
Mouse
regulation of catabolic process GO:0009894 170 0.013
Mouse
regulation of mrna metabolic process GO:1903311 72 0.013
multicellular organismal aging GO:0010259 140 0.013
eye development GO:0001654 323 0.012
Fly
dna conformation change GO:0071103 105 0.012
adult behavior GO:0030534 137 0.012
cell death GO:0008219 279 0.012
multicellular organismal homeostasis GO:0048871 41 0.012
organonitrogen compound metabolic process GO:1901564 318 0.012
regulation of molecular function GO:0065009 217 0.012
response to other organism GO:0051707 293 0.012
response to organonitrogen compound GO:0010243 75 0.012
Fly
memory GO:0007613 94 0.012
eye morphogenesis GO:0048592 260 0.012
Fly
protein acylation GO:0043543 42 0.012
response to lipopolysaccharide GO:0032496 4 0.012
negative regulation of developmental process GO:0051093 201 0.012
Mouse
positive regulation of signaling GO:0023056 243 0.012
Mouse
cellular amino acid metabolic process GO:0006520 61 0.012
regulation of insulin secretion GO:0050796 5 0.012
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.012
phosphorylation GO:0016310 294 0.012
developmental growth GO:0048589 280 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
regulation of cell cycle process GO:0010564 181 0.012
cellular response to ionizing radiation GO:0071479 15 0.012
detection of light stimulus GO:0009583 58 0.012
regulation of catalytic activity GO:0050790 185 0.012
regulation of response to stress GO:0080134 200 0.012
Mouse
dopamine receptor signaling pathway GO:0007212 4 0.012
chemotaxis GO:0006935 249 0.012
regulation of embryonic development GO:0045995 68 0.011
branching morphogenesis of an epithelial tube GO:0048754 45 0.011
oocyte development GO:0048599 124 0.011
female meiotic division GO:0007143 70 0.011
chromosome segregation GO:0007059 157 0.011
oocyte construction GO:0007308 112 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
mrna processing GO:0006397 104 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
respiratory system development GO:0060541 213 0.011
positive regulation of signal transduction GO:0009967 223 0.011
Mouse
negative regulation of mitotic cell cycle GO:0045930 109 0.011
proteolysis GO:0006508 192 0.011
Mouse
response to ionizing radiation GO:0010212 32 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
spermatid differentiation GO:0048515 114 0.011
regulation of response to external stimulus GO:0032101 115 0.011
secretion by cell GO:0032940 101 0.011
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.011
protein dna complex assembly GO:0065004 63 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
regulation of immune response GO:0050776 118 0.010
spinal cord development GO:0021510 1 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of heart contraction GO:0008016 21 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
Mouse Fly

cyc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.019