Drosophila melanogaster

78 known processes

Ih (Dmel_CG8585)

I[[h]] channel

(Aliases: CG8585,DMIH,Dmel\CG8585)

Ih biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 0.996
rhythmic behavior GO:0007622 76 0.736
circadian behavior GO:0048512 76 0.704
rhythmic process GO:0048511 106 0.669
locomotory behavior GO:0007626 176 0.622
locomotor rhythm GO:0045475 56 0.532
single organism behavior GO:0044708 391 0.527
sleep GO:0030431 49 0.483
regulation of circadian rhythm GO:0042752 49 0.263
circadian sleep wake cycle process GO:0022410 24 0.262
regulation of behavior GO:0050795 75 0.240
circadian sleep wake cycle sleep GO:0050802 23 0.233
response to trehalose GO:0010353 3 0.233
cation transmembrane transport GO:0098655 88 0.188
detection of stimulus involved in sensory perception GO:0050906 92 0.157
camp biosynthetic process GO:0006171 17 0.154
ion transmembrane transport GO:0034220 122 0.154
sensory perception of chemical stimulus GO:0007606 116 0.147
positive regulation of behavior GO:0048520 19 0.133
meiotic cell cycle GO:0051321 171 0.128
synaptic transmission GO:0007268 288 0.126
purine ribonucleotide biosynthetic process GO:0009152 28 0.126
establishment of localization in cell GO:0051649 402 0.123
small molecule metabolic process GO:0044281 305 0.108
anatomical structure homeostasis GO:0060249 97 0.106
organelle fission GO:0048285 340 0.102
meiotic nuclear division GO:0007126 151 0.099
detection of stimulus GO:0051606 156 0.099
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.099
detection of chemical stimulus GO:0009593 93 0.097
positive regulation of response to stimulus GO:0048584 323 0.094
organonitrogen compound metabolic process GO:1901564 318 0.092
regulation of circadian sleep wake cycle GO:0042749 25 0.090
regulation of transmembrane transport GO:0034762 27 0.087
learning or memory GO:0007611 141 0.084
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.082
homeostatic process GO:0042592 199 0.076
sensory perception of taste GO:0050909 25 0.076
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.076
detection of chemical stimulus involved in sensory perception of taste GO:0050912 13 0.075
circadian sleep wake cycle GO:0042745 28 0.074
eye morphogenesis GO:0048592 260 0.072
neurological system process GO:0050877 358 0.070
nuclear division GO:0000280 332 0.070
cyclic nucleotide biosynthetic process GO:0009190 25 0.070
sensory perception of sweet taste GO:0050916 14 0.068
appendage morphogenesis GO:0035107 397 0.067
cyclic nucleotide metabolic process GO:0009187 28 0.067
sensory organ morphogenesis GO:0090596 260 0.065
negative regulation of signaling GO:0023057 219 0.063
female meiotic division GO:0007143 70 0.060
molting cycle chitin based cuticle GO:0007591 56 0.058
response to monosaccharide GO:0034284 4 0.058
chaeta development GO:0022416 97 0.058
carbohydrate derivative biosynthetic process GO:1901137 85 0.058
response to light stimulus GO:0009416 124 0.056
compound eye morphogenesis GO:0001745 249 0.054
transmembrane transport GO:0055085 139 0.054
eye development GO:0001654 323 0.054
response to starvation GO:0042594 97 0.054
appendage development GO:0048736 401 0.053
response to hexose GO:0009746 3 0.053
ion transport GO:0006811 145 0.052
regulation of nervous system development GO:0051960 248 0.051
multi organism behavior GO:0051705 175 0.051
detection of chemical stimulus involved in sensory perception of sweet taste GO:0001582 11 0.051
developmental growth GO:0048589 280 0.050
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 7 0.050
muscle cell development GO:0055001 50 0.049
metal ion transport GO:0030001 74 0.049
cell proliferation GO:0008283 299 0.049
adult behavior GO:0030534 137 0.047
multicellular organism growth GO:0035264 46 0.047
organic substance catabolic process GO:1901575 308 0.047
negative regulation of response to stimulus GO:0048585 258 0.046
organophosphate metabolic process GO:0019637 195 0.046
response to organic substance GO:0010033 284 0.046
purine containing compound biosynthetic process GO:0072522 30 0.045
regulation of molecular function GO:0065009 217 0.045
purine containing compound metabolic process GO:0072521 155 0.044
purine nucleotide biosynthetic process GO:0006164 29 0.044
carbohydrate derivative metabolic process GO:1901135 217 0.043
regulation of multicellular organism growth GO:0040014 40 0.043
detection of abiotic stimulus GO:0009582 66 0.043
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
camp metabolic process GO:0046058 19 0.043
response to glucose GO:0009749 2 0.042
defense response GO:0006952 300 0.042
compound eye development GO:0048749 307 0.041
response to endogenous stimulus GO:0009719 119 0.040
regulation of membrane potential GO:0042391 35 0.040
intracellular transport GO:0046907 228 0.040
negative regulation of cell communication GO:0010648 223 0.040
negative regulation of growth GO:0045926 84 0.039
response to organic cyclic compound GO:0014070 89 0.039
negative regulation of developmental growth GO:0048640 64 0.039
nucleoside phosphate metabolic process GO:0006753 162 0.038
nucleoside phosphate biosynthetic process GO:1901293 34 0.038
intracellular signal transduction GO:0035556 300 0.038
sensory perception GO:0007600 196 0.038
single organism cellular localization GO:1902580 180 0.037
protein targeting to nucleus GO:0044744 51 0.037
catabolic process GO:0009056 409 0.037
response to nitrogen compound GO:1901698 90 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
purine ribonucleotide metabolic process GO:0009150 145 0.037
regulation of system process GO:0044057 36 0.037
response to radiation GO:0009314 155 0.036
cell cycle phase transition GO:0044770 140 0.035
organophosphate biosynthetic process GO:0090407 46 0.035
protein modification process GO:0036211 438 0.035
response to oxygen containing compound GO:1901700 200 0.034
striated muscle cell differentiation GO:0051146 90 0.034
regulation of cellular localization GO:0060341 136 0.034
ribonucleotide biosynthetic process GO:0009260 28 0.033
positive regulation of multicellular organismal process GO:0051240 143 0.032
olfactory learning GO:0008355 56 0.032
intraspecies interaction between organisms GO:0051703 4 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
nitrogen compound transport GO:0071705 85 0.031
single organism biosynthetic process GO:0044711 206 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.031
ribose phosphate metabolic process GO:0019693 145 0.030
cell death GO:0008219 279 0.030
nucleotide biosynthetic process GO:0009165 34 0.030
response to abiotic stimulus GO:0009628 341 0.029
regulation of localization GO:0032879 275 0.029
cellular homeostasis GO:0019725 80 0.029
ribose phosphate biosynthetic process GO:0046390 28 0.029
protein localization to nucleus GO:0034504 55 0.029
detection of external stimulus GO:0009581 66 0.028
g protein coupled receptor signaling pathway GO:0007186 136 0.028
regulation of developmental growth GO:0048638 174 0.028
axon development GO:0061564 297 0.028
nucleotide metabolic process GO:0009117 161 0.028
cellular response to monosaccharide stimulus GO:0071326 2 0.027
cellular catabolic process GO:0044248 372 0.027
chemosensory behavior GO:0007635 106 0.027
regulation of intracellular protein transport GO:0033157 46 0.027
response to organophosphorus GO:0046683 2 0.027
wing disc morphogenesis GO:0007472 344 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
organic acid metabolic process GO:0006082 103 0.026
l amino acid import GO:0043092 2 0.025
cellular response to oxygen containing compound GO:1901701 79 0.025
positive regulation of gene expression GO:0010628 290 0.025
cognition GO:0050890 141 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
mating behavior GO:0007617 106 0.024
kidney development GO:0001822 3 0.024
enzyme linked receptor protein signaling pathway GO:0007167 179 0.024
response to alkaloid GO:0043279 26 0.024
growth GO:0040007 359 0.024
response to metal ion GO:0010038 23 0.024
long term memory GO:0007616 62 0.024
eye photoreceptor cell development GO:0042462 81 0.024
actin filament based process GO:0030029 220 0.024
regulation of multicellular organismal development GO:2000026 414 0.023
regulation of anatomical structure morphogenesis GO:0022603 242 0.023
establishment of organelle localization GO:0051656 122 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
cellular protein modification process GO:0006464 438 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
negative regulation of signal transduction GO:0009968 206 0.022
organic substance transport GO:0071702 257 0.022
vesicle mediated transport GO:0016192 381 0.022
actin cytoskeleton organization GO:0030036 206 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
synapse organization GO:0050808 196 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
response to lipopolysaccharide GO:0032496 4 0.021
protein localization GO:0008104 284 0.021
regulation of synaptic transmission GO:0050804 69 0.021
membrane depolarization GO:0051899 4 0.021
cytoplasmic transport GO:0016482 130 0.021
male gamete generation GO:0048232 201 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
tissue morphogenesis GO:0048729 297 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
nucleocytoplasmic transport GO:0006913 72 0.020
intracellular protein transport GO:0006886 104 0.020
protein import GO:0017038 55 0.020
negative regulation of insulin secretion GO:0046676 1 0.020
olfactory behavior GO:0042048 97 0.020
phagocytosis GO:0006909 215 0.020
nuclear transport GO:0051169 72 0.020
cellular amino acid metabolic process GO:0006520 61 0.019
cellular response to hexose stimulus GO:0071331 1 0.019
positive regulation of signal transduction GO:0009967 223 0.019
regulation of cell differentiation GO:0045595 302 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
response to extracellular stimulus GO:0009991 116 0.019
epidermal growth factor receptor signaling pathway GO:0007173 58 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010578 8 0.019
regulation of neurogenesis GO:0050767 158 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
tube development GO:0035295 244 0.019
macromolecule catabolic process GO:0009057 161 0.019
cation transport GO:0006812 110 0.019
secretion GO:0046903 109 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
positive regulation of cell communication GO:0010647 250 0.019
positive regulation of cellular component organization GO:0051130 156 0.018
defense response to other organism GO:0098542 225 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.018
response to carbohydrate GO:0009743 15 0.018
cellular macromolecule localization GO:0070727 220 0.018
regulation of neuron differentiation GO:0045664 103 0.018
establishment of protein localization GO:0045184 163 0.018
regulation of olfactory learning GO:0090328 8 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
gene silencing GO:0016458 138 0.018
regulation of cell cycle GO:0051726 291 0.018
axon guidance GO:0007411 233 0.018
dephosphorylation GO:0016311 51 0.017
regulation of immune system process GO:0002682 176 0.017
cellular protein localization GO:0034613 160 0.017
sensory perception of smell GO:0007608 80 0.017
phosphorylation GO:0016310 294 0.017
cellular response to organic substance GO:0071310 132 0.017
immune system process GO:0002376 347 0.017
developmental maturation GO:0021700 172 0.017
spermatogenesis GO:0007283 200 0.017
regulation of transmembrane transporter activity GO:0022898 6 0.017
single organism catabolic process GO:0044712 228 0.017
negative regulation of developmental process GO:0051093 201 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
memory GO:0007613 94 0.017
response to caffeine GO:0031000 12 0.017
response to purine containing compound GO:0014074 12 0.017
oxoacid metabolic process GO:0043436 103 0.017
immune response activating signal transduction GO:0002757 2 0.017
molting cycle process GO:0022404 29 0.017
mitotic cell cycle phase transition GO:0044772 138 0.016
protein dephosphorylation GO:0006470 27 0.016
epithelial cell differentiation GO:0030855 322 0.016
amine metabolic process GO:0009308 12 0.016
telencephalon development GO:0021537 2 0.016
positive regulation of nervous system development GO:0051962 69 0.016
courtship behavior GO:0007619 68 0.016
tyrosine metabolic process GO:0006570 1 0.016
photoreceptor cell development GO:0042461 96 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
muscle cell differentiation GO:0042692 103 0.016
regulation of catabolic process GO:0009894 170 0.016
synaptic vesicle localization GO:0097479 53 0.016
regulation of response to external stimulus GO:0032101 115 0.016
single organism intracellular transport GO:1902582 207 0.016
regulation of protein localization GO:0032880 76 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
multi multicellular organism process GO:0044706 123 0.015
proteolysis GO:0006508 192 0.015
adult locomotory behavior GO:0008344 76 0.015
regulation of protein metabolic process GO:0051246 256 0.015
positive regulation of signaling GO:0023056 243 0.015
purine containing compound catabolic process GO:0072523 112 0.015
central nervous system development GO:0007417 201 0.015
cellular amine metabolic process GO:0044106 12 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
nuclear import GO:0051170 51 0.014
muscle structure development GO:0061061 224 0.014
regulation of proteolysis GO:0030162 87 0.014
protein localization to organelle GO:0033365 82 0.014
myotube cell development GO:0014904 3 0.014
detection of light stimulus GO:0009583 58 0.014
cell migration GO:0016477 238 0.014
regulation of response to stress GO:0080134 200 0.014
positive regulation of cell proliferation GO:0008284 47 0.014
learning GO:0007612 75 0.014
chemotaxis GO:0006935 249 0.014
brain development GO:0007420 120 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
regulation of catalytic activity GO:0050790 185 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
axonogenesis GO:0007409 290 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
regulation of cell development GO:0060284 215 0.014
protein targeting GO:0006605 64 0.013
regulation of cellular component size GO:0032535 98 0.013
regulation of transport GO:0051049 181 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
localization of cell GO:0051674 257 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
macromolecular complex assembly GO:0065003 256 0.013
negative regulation of molecular function GO:0044092 51 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
dendrite development GO:0016358 204 0.013
single organism nuclear import GO:1902593 51 0.013
response to inorganic substance GO:0010035 44 0.013
regulation of anatomical structure size GO:0090066 163 0.013
synapse assembly GO:0007416 143 0.013
neuron projection guidance GO:0097485 241 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
detection of hexose stimulus GO:0009732 1 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
compound eye photoreceptor development GO:0042051 78 0.013
respiratory system development GO:0060541 213 0.013
peptide metabolic process GO:0006518 80 0.013
positive regulation of molecular function GO:0044093 136 0.013
protein phosphorylation GO:0006468 169 0.013
multi organism reproductive behavior GO:0044705 121 0.013
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.013
regulation of intracellular transport GO:0032386 64 0.013
response to temperature stimulus GO:0009266 106 0.013
endocytosis GO:0006897 310 0.013
camera type eye morphogenesis GO:0048593 2 0.012
regulation of adenylate cyclase activity GO:0045761 12 0.012
neuropeptide signaling pathway GO:0007218 45 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of protein kinase activity GO:0045859 51 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular response to ethanol GO:0071361 4 0.012
response to bacterium GO:0009617 198 0.012
protein complex assembly GO:0006461 200 0.012
activation of innate immune response GO:0002218 4 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
regulation of cell projection organization GO:0031344 92 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of multi organism process GO:0043900 131 0.012
response to nutrient levels GO:0031667 114 0.012
protein import into nucleus GO:0006606 51 0.012
chemical homeostasis GO:0048878 92 0.012
antibacterial humoral response GO:0019731 44 0.012
cell growth GO:0016049 108 0.012
taxis GO:0042330 304 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
regulation of hydrolase activity GO:0051336 97 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
negative regulation of neural precursor cell proliferation GO:2000178 27 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
neuromuscular synaptic transmission GO:0007274 67 0.012
regulation of camp metabolic process GO:0030814 12 0.012
positive regulation of developmental growth GO:0048639 62 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
striated muscle cell development GO:0055002 50 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
tissue death GO:0016271 102 0.011
regulation of cell death GO:0010941 173 0.011
protein catabolic process GO:0030163 101 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
regulation of camp biosynthetic process GO:0030817 12 0.011
heart process GO:0003015 37 0.011
neuron remodeling GO:0016322 29 0.011
erbb signaling pathway GO:0038127 58 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
protein transport GO:0015031 155 0.011
cell cycle checkpoint GO:0000075 95 0.011
retina development in camera type eye GO:0060041 4 0.011
response to lipid GO:0033993 38 0.011
muscle tissue development GO:0060537 30 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
neuron recognition GO:0008038 101 0.011
programmed cell death GO:0012501 257 0.011
body morphogenesis GO:0010171 2 0.011
nucleoside catabolic process GO:0009164 112 0.011
cell division GO:0051301 248 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
regionalization GO:0003002 416 0.011
response to other organism GO:0051707 293 0.011
signal release GO:0023061 49 0.011
multicellular organismal aging GO:0010259 140 0.011
response to biotic stimulus GO:0009607 294 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
nucleus organization GO:0006997 45 0.011
regulation of phosphorylation GO:0042325 147 0.011
protein complex biogenesis GO:0070271 201 0.011
organelle assembly GO:0070925 198 0.011
cellular protein catabolic process GO:0044257 83 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
organelle localization GO:0051640 148 0.011
mitotic nuclear division GO:0007067 213 0.011
positive regulation of cell development GO:0010720 61 0.011
heterocycle catabolic process GO:0046700 166 0.011
molting cycle GO:0042303 56 0.011
aromatic compound catabolic process GO:0019439 166 0.011
response to organonitrogen compound GO:0010243 75 0.011
regulation of neuron projection development GO:0010975 69 0.011
neurotransmitter transport GO:0006836 37 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
mesenchymal cell development GO:0014031 1 0.011
regulation of neurotransmitter secretion GO:0046928 14 0.011
forebrain development GO:0030900 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
camera type eye development GO:0043010 4 0.010
extracellular structure organization GO:0043062 46 0.010
negative regulation of cellular biosynthetic process GO:0031327 277 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
muscle organ development GO:0007517 127 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
pattern recognition receptor signaling pathway GO:0002221 2 0.010
response to disaccharide GO:0034285 12 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
regulation of growth GO:0040008 233 0.010
circulatory system development GO:0072359 82 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
skeletal muscle fiber development GO:0048741 3 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010
gland development GO:0048732 191 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
death GO:0016265 284 0.010

Ih disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.020
urinary system disease DOID:18 0 0.020
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
cardiovascular system disease DOID:1287 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
kidney disease DOID:557 0 0.011
central nervous system disease DOID:331 0 0.010