Drosophila melanogaster

0 known processes

CG8586 (Dmel_CG8586)

CG8586 gene product from transcript CG8586-RA

(Aliases: SPH58,Dmel\CG8586,c-SPH58)

CG8586 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune response GO:0006955 246 0.192
response to bacterium GO:0009617 198 0.169
Fly
immune system process GO:0002376 347 0.140
Fly
defense response GO:0006952 300 0.136
Fly
innate immune response GO:0045087 144 0.133
peptide metabolic process GO:0006518 80 0.129
response to fungus GO:0009620 50 0.124
regulation of immune system process GO:0002682 176 0.121
Fly
response to biotic stimulus GO:0009607 294 0.097
Fly
regulation of immune response GO:0050776 118 0.087
defense response to fungus GO:0050832 48 0.086
antimicrobial peptide production GO:0002775 46 0.080
regulation of multi organism process GO:0043900 131 0.080
regionalization GO:0003002 416 0.072
regulation of cellular amide metabolic process GO:0034248 39 0.070
vesicle mediated transport GO:0016192 381 0.069
gland morphogenesis GO:0022612 145 0.069
regulation of response to stress GO:0080134 200 0.068
antimicrobial humoral response GO:0019730 99 0.068
response to external biotic stimulus GO:0043207 293 0.067
Fly
response to other organism GO:0051707 293 0.066
Fly
developmental programmed cell death GO:0010623 138 0.065
immune effector process GO:0002252 98 0.064
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.063
organonitrogen compound metabolic process GO:1901564 318 0.062
regulation of immune effector process GO:0002697 52 0.062
production of molecular mediator of immune response GO:0002440 46 0.058
cellular ketone metabolic process GO:0042180 24 0.057
endocytosis GO:0006897 310 0.056
axis specification GO:0009798 167 0.056
cellular amide metabolic process GO:0043603 80 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.054
protein maturation GO:0051604 71 0.052
defense response to other organism GO:0098542 225 0.052
Fly
regulation of antimicrobial peptide production GO:0002784 44 0.052
response to wounding GO:0009611 94 0.051
regulation of production of molecular mediator of immune response GO:0002700 44 0.051
dorsal ventral axis specification GO:0009950 66 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.049
death GO:0016265 284 0.048
salivary gland morphogenesis GO:0007435 145 0.047
wound healing GO:0042060 75 0.047
regulation of antimicrobial humoral response GO:0002759 50 0.046
gland development GO:0048732 191 0.044
negative regulation of cell communication GO:0010648 223 0.044
positive regulation of response to external stimulus GO:0032103 44 0.043
response to abiotic stimulus GO:0009628 341 0.043
positive regulation of response to stimulus GO:0048584 323 0.043
cell death GO:0008219 279 0.043
regulation of response to external stimulus GO:0032101 115 0.042
phagocytosis GO:0006909 215 0.040
catabolic process GO:0009056 409 0.040
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.039
homeostatic process GO:0042592 199 0.039
defense response to gram negative bacterium GO:0050829 94 0.038
positive regulation of immune effector process GO:0002699 28 0.038
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.037
toll signaling pathway GO:0008063 25 0.037
proteolysis GO:0006508 192 0.036
single organism behavior GO:0044708 391 0.036
regulation of humoral immune response GO:0002920 51 0.036
salivary gland development GO:0007431 162 0.036
positive regulation of biosynthetic process GO:0009891 316 0.035
regulation of response to biotic stimulus GO:0002831 63 0.035
autophagic cell death GO:0048102 83 0.035
exocrine system development GO:0035272 162 0.035
lateral inhibition GO:0046331 206 0.034
positive regulation of melanization defense response GO:0035008 1 0.034
positive regulation of antimicrobial peptide production GO:0002225 28 0.034
organic substance catabolic process GO:1901575 308 0.034
histolysis GO:0007559 102 0.033
cell proliferation GO:0008283 299 0.033
Fly
positive regulation of cellular amide metabolic process GO:0034250 26 0.033
negative regulation of response to stimulus GO:0048585 258 0.032
positive regulation of response to biotic stimulus GO:0002833 31 0.032
salivary gland histolysis GO:0035070 88 0.032
regulation of innate immune response GO:0045088 71 0.031
positive regulation of multi organism process GO:0043902 40 0.031
organic substance transport GO:0071702 257 0.031
antimicrobial peptide biosynthetic process GO:0002777 38 0.031
multi organism behavior GO:0051705 175 0.031
amide biosynthetic process GO:0043604 42 0.030
developmental pigmentation GO:0048066 68 0.030
defense response to bacterium GO:0042742 178 0.030
Fly
salivary gland cell autophagic cell death GO:0035071 83 0.030
positive regulation of cell communication GO:0010647 250 0.029
response to organophosphorus GO:0046683 2 0.029
dorsal ventral pattern formation GO:0009953 133 0.029
eye development GO:0001654 323 0.029
phenol containing compound metabolic process GO:0018958 57 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
organonitrogen compound biosynthetic process GO:1901566 117 0.028
single organism catabolic process GO:0044712 228 0.028
humoral immune response GO:0006959 117 0.027
programmed cell death GO:0012501 257 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
negative regulation of signal transduction GO:0009968 206 0.026
detection of stimulus GO:0051606 156 0.025
small molecule metabolic process GO:0044281 305 0.025
protein processing GO:0016485 68 0.025
regulation of body fluid levels GO:0050878 14 0.024
antibacterial peptide biosynthetic process GO:0002780 22 0.024
tissue death GO:0016271 102 0.024
positive regulation of antimicrobial humoral response GO:0002760 28 0.024
regulation of toll signaling pathway GO:0008592 17 0.024
regulation of molecular function GO:0065009 217 0.023
lipid metabolic process GO:0006629 121 0.023
cell recognition GO:0008037 102 0.023
zymogen activation GO:0031638 20 0.023
positive regulation of signaling GO:0023056 243 0.022
positive regulation of signal transduction GO:0009967 223 0.022
pigmentation GO:0043473 75 0.022
regulation of endopeptidase activity GO:0052548 36 0.022
positive regulation of immune system process GO:0002684 68 0.022
Fly
small molecule biosynthetic process GO:0044283 37 0.022
pigment metabolic process GO:0042440 84 0.022
single organism biosynthetic process GO:0044711 206 0.021
steroid biosynthetic process GO:0006694 16 0.021
hormone catabolic process GO:0042447 3 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
sensory organ morphogenesis GO:0090596 260 0.021
lipid localization GO:0010876 54 0.021
response to nutrient levels GO:0031667 114 0.020
establishment of localization in cell GO:0051649 402 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
chemical homeostasis GO:0048878 92 0.020
protein modification process GO:0036211 438 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
antifungal humoral response GO:0019732 12 0.020
kidney development GO:0001822 3 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
defense response to gram positive bacterium GO:0050830 41 0.019
Fly
organic hydroxy compound metabolic process GO:1901615 83 0.019
negative regulation of signaling GO:0023057 219 0.019
negative regulation of gene expression GO:0010629 387 0.019
sterol homeostasis GO:0055092 4 0.019
regulation of cell proliferation GO:0042127 163 0.019
Fly
appendage development GO:0048736 401 0.019
positive regulation of humoral immune response GO:0002922 28 0.019
mesoderm development GO:0007498 78 0.019
peptide biosynthetic process GO:0043043 42 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
wing disc morphogenesis GO:0007472 344 0.018
synaptic transmission GO:0007268 288 0.018
cellular protein modification process GO:0006464 438 0.018
cellular hormone metabolic process GO:0034754 23 0.017
regulation of catalytic activity GO:0050790 185 0.017
regulation of transport GO:0051049 181 0.017
multi multicellular organism process GO:0044706 123 0.017
steroid metabolic process GO:0008202 20 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
neurological system process GO:0050877 358 0.017
melanization defense response GO:0035006 45 0.017
compound eye development GO:0048749 307 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
regulation of cell cycle GO:0051726 291 0.017
oxoacid metabolic process GO:0043436 103 0.017
growth GO:0040007 359 0.016
appendage morphogenesis GO:0035107 397 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
intracellular signal transduction GO:0035556 300 0.016
melanin metabolic process GO:0006582 47 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
negative regulation of developmental process GO:0051093 201 0.016
nuclear division GO:0000280 332 0.016
androgen metabolic process GO:0008209 1 0.016
organic acid metabolic process GO:0006082 103 0.015
response to radiation GO:0009314 155 0.015
connective tissue development GO:0061448 3 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
macromolecule catabolic process GO:0009057 161 0.015
developmental growth GO:0048589 280 0.015
detection of abiotic stimulus GO:0009582 66 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
positive regulation of defense response GO:0031349 59 0.015
reproductive behavior GO:0019098 122 0.015
response to organic substance GO:0010033 284 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of defense response GO:0031347 102 0.015
phototransduction GO:0007602 52 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.014
positive regulation of cell migration GO:0030335 2 0.014
mating behavior GO:0007617 106 0.014
detection of external stimulus GO:0009581 66 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
response to organic cyclic compound GO:0014070 89 0.014
regulation of proteolysis GO:0030162 87 0.013
phosphorylation GO:0016310 294 0.013
positive regulation of immune response GO:0050778 63 0.013
body morphogenesis GO:0010171 2 0.013
ras protein signal transduction GO:0007265 88 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
rna localization GO:0006403 115 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
biological adhesion GO:0022610 138 0.013
response to oxygen containing compound GO:1901700 200 0.013
mitotic nuclear division GO:0007067 213 0.013
response to lipopolysaccharide GO:0032496 4 0.012
positive regulation of innate immune response GO:0045089 38 0.012
anatomical structure homeostasis GO:0060249 97 0.012
nucleus organization GO:0006997 45 0.012
positive regulation of cell motility GO:2000147 3 0.012
macromolecular complex assembly GO:0065003 256 0.012
wnt signaling pathway GO:0016055 98 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
positive regulation of gene expression GO:0010628 290 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
negative regulation of defense response GO:0031348 35 0.012
organelle fission GO:0048285 340 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
positive regulation of antibacterial peptide production GO:0002803 20 0.012
spindle organization GO:0007051 253 0.012
response to light stimulus GO:0009416 124 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
immune response activating signal transduction GO:0002757 2 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
aromatic compound catabolic process GO:0019439 166 0.011
response to nitrogen compound GO:1901698 90 0.011
negative regulation of peptide hormone processing GO:0060570 1 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
synaptic target recognition GO:0008039 45 0.011
camera type eye development GO:0043010 4 0.011
mating GO:0007618 120 0.011
eye pigment biosynthetic process GO:0006726 32 0.011
cholesterol transport GO:0030301 2 0.011
regulation of hydrolase activity GO:0051336 97 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
response to monosaccharide GO:0034284 4 0.011
imaginal disc pattern formation GO:0007447 91 0.011
response to endogenous stimulus GO:0009719 119 0.011
regulation of catabolic process GO:0009894 170 0.011
wing disc pattern formation GO:0035222 66 0.010
actin filament based process GO:0030029 220 0.010
cellular catabolic process GO:0044248 372 0.010
intracellular transport GO:0046907 228 0.010
amine metabolic process GO:0009308 12 0.010
rhythmic process GO:0048511 106 0.010
heterocycle catabolic process GO:0046700 166 0.010
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
response to organonitrogen compound GO:0010243 75 0.010

CG8586 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.024
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.014