Drosophila melanogaster

0 known processes

Sh3beta (Dmel_CG8582)

CG8582 gene product from transcript CG8582-RD

(Aliases: Dmel\CG8582,LD12912,SH3beta,CG8582)

Sh3beta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 220 0.311
macromolecular complex assembly GO:0065003 256 0.216
response to carbon dioxide GO:0010037 4 0.210
protein localization GO:0008104 284 0.206
protein complex assembly GO:0006461 200 0.200
response to extracellular stimulus GO:0009991 116 0.196
biological adhesion GO:0022610 138 0.189
regulation of anatomical structure morphogenesis GO:0022603 242 0.180
negative regulation of rna metabolic process GO:0051253 251 0.179
response to nutrient levels GO:0031667 114 0.177
blood circulation GO:0008015 26 0.168
g2 dna damage checkpoint GO:0031572 69 0.165
response to abiotic stimulus GO:0009628 341 0.160
intracellular signal transduction GO:0035556 300 0.159
establishment of localization in cell GO:0051649 402 0.157
response to oxygen containing compound GO:1901700 200 0.140
phosphorylation GO:0016310 294 0.137
embryonic morphogenesis GO:0048598 206 0.130
cell migration GO:0016477 238 0.128
pigment metabolic process GO:0042440 84 0.115
male gamete generation GO:0048232 201 0.113
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.110
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.103
cellular response to starvation GO:0009267 61 0.101
negative regulation of gene expression GO:0010629 387 0.098
actin filament organization GO:0007015 126 0.090
eye development GO:0001654 323 0.089
ras protein signal transduction GO:0007265 88 0.088
post embryonic appendage morphogenesis GO:0035120 385 0.088
eye morphogenesis GO:0048592 260 0.082
regulation of localization GO:0032879 275 0.082
cellular macromolecular complex assembly GO:0034622 153 0.082
protein complex biogenesis GO:0070271 201 0.081
regulation of intracellular signal transduction GO:1902531 236 0.081
cellular response to dna damage stimulus GO:0006974 223 0.080
actin cytoskeleton organization GO:0030036 206 0.076
establishment or maintenance of cell polarity GO:0007163 167 0.074
positive regulation of cell communication GO:0010647 250 0.073
embryonic development via the syncytial blastoderm GO:0001700 148 0.073
negative regulation of cellular biosynthetic process GO:0031327 277 0.073
negative regulation of biosynthetic process GO:0009890 277 0.071
regulation of anatomical structure size GO:0090066 163 0.070
response to starvation GO:0042594 97 0.069
growth GO:0040007 359 0.068
cytoskeleton dependent cytokinesis GO:0061640 81 0.067
cellular catabolic process GO:0044248 372 0.066
imaginal disc derived appendage development GO:0048737 399 0.065
negative regulation of rna biosynthetic process GO:1902679 240 0.065
meiotic nuclear division GO:0007126 151 0.064
cell adhesion GO:0007155 136 0.063
regulation of response to stress GO:0080134 200 0.062
positive regulation of nucleic acid templated transcription GO:1903508 266 0.062
phagocytosis GO:0006909 215 0.062
response to temperature stimulus GO:0009266 106 0.062
cellular response to nutrient levels GO:0031669 62 0.062
regulation of developmental growth GO:0048638 174 0.061
regulation of cell shape GO:0008360 113 0.061
pigmentation GO:0043473 75 0.060
catabolic process GO:0009056 409 0.060
positive regulation of signaling GO:0023056 243 0.058
regulation of nervous system development GO:0051960 248 0.057
embryonic ectodermal digestive tract development GO:0048611 4 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.055
regulation of endocytosis GO:0030100 37 0.055
membrane organization GO:0061024 112 0.054
regionalization GO:0003002 416 0.053
muscle structure development GO:0061061 224 0.052
heart development GO:0007507 82 0.051
cell death GO:0008219 279 0.050
regulation of small gtpase mediated signal transduction GO:0051056 93 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.048
vesicle mediated transport GO:0016192 381 0.048
meiotic cell cycle process GO:1903046 132 0.048
single organism membrane budding GO:1902591 2 0.047
compound eye development GO:0048749 307 0.047
rac protein signal transduction GO:0016601 3 0.047
organonitrogen compound metabolic process GO:1901564 318 0.046
secondary metabolic process GO:0019748 75 0.046
cellular response to extracellular stimulus GO:0031668 64 0.045
cell proliferation GO:0008283 299 0.044
regulation of cellular component size GO:0032535 98 0.044
digestive tract morphogenesis GO:0048546 127 0.044
positive regulation of macromolecule metabolic process GO:0010604 405 0.043
endocytosis GO:0006897 310 0.043
sensory organ morphogenesis GO:0090596 260 0.043
nuclear transport GO:0051169 72 0.043
muscle system process GO:0003012 21 0.042
amine metabolic process GO:0009308 12 0.042
circulatory system process GO:0003013 37 0.042
positive regulation of signal transduction GO:0009967 223 0.042
nucleocytoplasmic transport GO:0006913 72 0.042
detection of light stimulus GO:0009583 58 0.042
transcription from rna polymerase ii promoter GO:0006366 368 0.041
immune effector process GO:0002252 98 0.041
death GO:0016265 284 0.041
chaeta development GO:0022416 97 0.040
establishment of protein localization GO:0045184 163 0.040
peripheral nervous system development GO:0007422 52 0.040
cellularization GO:0007349 90 0.040
heart process GO:0003015 37 0.039
regulation of actin filament based process GO:0032970 42 0.038
cellular protein localization GO:0034613 160 0.037
small gtpase mediated signal transduction GO:0007264 88 0.037
single organism behavior GO:0044708 391 0.037
detection of abiotic stimulus GO:0009582 66 0.036
positive regulation of protein metabolic process GO:0051247 128 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.036
positive regulation of gene expression GO:0010628 290 0.035
mitotic spindle elongation GO:0000022 81 0.035
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
regulation of protein metabolic process GO:0051246 256 0.034
reproductive structure development GO:0048608 74 0.034
arp2 3 complex mediated actin nucleation GO:0034314 3 0.034
cellular response to chemical stimulus GO:0070887 199 0.034
autophagy GO:0006914 108 0.033
tissue morphogenesis GO:0048729 297 0.033
cell junction organization GO:0034330 57 0.033
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.033
regulation of vesicle mediated transport GO:0060627 59 0.033
response to organophosphorus GO:0046683 2 0.033
meiotic cell cycle GO:0051321 171 0.033
negative regulation of transcription dna templated GO:0045892 237 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
protein targeting to nucleus GO:0044744 51 0.032
regulation of transport GO:0051049 181 0.032
regulation of protein polymerization GO:0032271 28 0.032
intracellular transport GO:0046907 228 0.032
cytokinesis GO:0000910 90 0.032
response to radiation GO:0009314 155 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
larval development GO:0002164 104 0.031
localization of cell GO:0051674 257 0.031
salivary gland histolysis GO:0035070 88 0.031
cellular protein complex assembly GO:0043623 71 0.031
positive regulation of developmental process GO:0051094 143 0.031
regulation of cellular response to stress GO:0080135 89 0.031
skeletal muscle organ development GO:0060538 48 0.030
melanization defense response GO:0035006 45 0.030
circulatory system development GO:0072359 82 0.030
aromatic compound catabolic process GO:0019439 166 0.029
regulation of cellular response to oxidative stress GO:1900407 4 0.029
protein modification process GO:0036211 438 0.029
positive regulation of cytoskeleton organization GO:0051495 21 0.029
tissue death GO:0016271 102 0.029
appendage morphogenesis GO:0035107 397 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
histolysis GO:0007559 102 0.029
autophagic vacuole assembly GO:0000045 2 0.029
regulation of cell death GO:0010941 173 0.029
organelle fission GO:0048285 340 0.029
cellular lipid metabolic process GO:0044255 83 0.028
protein localization to organelle GO:0033365 82 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
compound eye morphogenesis GO:0001745 249 0.027
single organism intracellular transport GO:1902582 207 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
septate junction assembly GO:0019991 26 0.027
regulation of organ morphogenesis GO:2000027 78 0.026
regulation of cell cycle GO:0051726 291 0.026
regulation of rac protein signal transduction GO:0035020 3 0.026
regulation of catabolic process GO:0009894 170 0.026
melanin metabolic process GO:0006582 47 0.026
cardiovascular system development GO:0072358 82 0.026
glycoprotein metabolic process GO:0009100 41 0.026
wing disc morphogenesis GO:0007472 344 0.026
heterocycle catabolic process GO:0046700 166 0.026
ethanolamine containing compound metabolic process GO:0042439 4 0.026
positive regulation of developmental growth GO:0048639 62 0.026
cell motility GO:0048870 251 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
epithelial cell differentiation GO:0030855 322 0.025
regulation of actin filament length GO:0030832 27 0.025
erbb signaling pathway GO:0038127 58 0.025
posttranscriptional regulation of gene expression GO:0010608 145 0.025
body morphogenesis GO:0010171 2 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
phototransduction GO:0007602 52 0.024
actin filament polymerization GO:0030041 27 0.024
appendage development GO:0048736 401 0.024
regulation of response to nutrient levels GO:0032107 18 0.024
chromosome segregation GO:0007059 157 0.024
negative regulation of cytoskeleton organization GO:0051494 30 0.024
regulation of programmed cell death GO:0043067 152 0.023
regulation of autophagy GO:0010506 62 0.023
morphogenesis of embryonic epithelium GO:0016331 94 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.023
endomembrane system organization GO:0010256 119 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
oxoacid metabolic process GO:0043436 103 0.023
striated muscle cell differentiation GO:0051146 90 0.023
regulation of actin polymerization or depolymerization GO:0008064 27 0.023
heart contraction GO:0060047 26 0.023
cellular nitrogen compound catabolic process GO:0044270 165 0.023
organophosphate metabolic process GO:0019637 195 0.022
meiotic cytokinesis GO:0033206 33 0.022
microtubule organizing center organization GO:0031023 168 0.022
negative regulation of signaling GO:0023057 219 0.022
single organism membrane organization GO:0044802 93 0.022
regulation of cellular catabolic process GO:0031329 157 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of system process GO:0044057 36 0.021
neurological system process GO:0050877 358 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
cellular response to organic substance GO:0071310 132 0.021
response to light stimulus GO:0009416 124 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
vesicle organization GO:0016050 44 0.021
endosomal vesicle fusion GO:0034058 4 0.021
spindle elongation GO:0051231 83 0.021
cell cell junction organization GO:0045216 55 0.020
notch signaling pathway GO:0007219 120 0.020
regulation of catalytic activity GO:0050790 185 0.020
protein heterooligomerization GO:0051291 4 0.020
response to biotic stimulus GO:0009607 294 0.020
negative regulation of cell communication GO:0010648 223 0.020
immune system process GO:0002376 347 0.020
multi organism behavior GO:0051705 175 0.020
regulation of synaptic transmission GO:0050804 69 0.020
positive regulation of protein modification process GO:0031401 58 0.020
phenol containing compound metabolic process GO:0018958 57 0.019
cell type specific apoptotic process GO:0097285 38 0.019
organelle assembly GO:0070925 198 0.019
cytoplasmic transport GO:0016482 130 0.019
cell cycle arrest GO:0007050 4 0.019
single organism catabolic process GO:0044712 228 0.019
forebrain development GO:0030900 2 0.019
lipid localization GO:0010876 54 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
axon development GO:0061564 297 0.019
intracellular protein transport GO:0006886 104 0.019
programmed cell death GO:0012501 257 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.018
single organism biosynthetic process GO:0044711 206 0.018
single organism cellular localization GO:1902580 180 0.018
hematopoietic progenitor cell differentiation GO:0002244 1 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
limb development GO:0060173 1 0.017
developmental programmed cell death GO:0010623 138 0.017
response to bacterium GO:0009617 198 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
response to endogenous stimulus GO:0009719 119 0.017
response to organic cyclic compound GO:0014070 89 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
dna integrity checkpoint GO:0031570 81 0.017
locomotory behavior GO:0007626 176 0.017
cellular macromolecule localization GO:0070727 220 0.017
nuclear import GO:0051170 51 0.017
response to inorganic substance GO:0010035 44 0.017
head development GO:0060322 135 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
cellular amine metabolic process GO:0044106 12 0.016
regulation of cell differentiation GO:0045595 302 0.016
salivary gland morphogenesis GO:0007435 145 0.016
regulation of growth GO:0040008 233 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
regulation of actin filament polymerization GO:0030833 25 0.016
organic substance transport GO:0071702 257 0.016
protein polymerization GO:0051258 42 0.016
compound eye retinal cell programmed cell death GO:0046667 23 0.016
regulation of actin cytoskeleton organization GO:0032956 42 0.016
regulation of macroautophagy GO:0016241 15 0.016
positive regulation of transport GO:0051050 92 0.016
sensory perception of mechanical stimulus GO:0050954 72 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.015
learning or memory GO:0007611 141 0.015
autophagic cell death GO:0048102 83 0.015
negative regulation of cell cycle GO:0045786 116 0.015
exocrine system development GO:0035272 162 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
response to other organism GO:0051707 293 0.015
regulation of organelle organization GO:0033043 196 0.015
syncytium formation GO:0006949 43 0.015
regulation of response to external stimulus GO:0032101 115 0.015
regulation of molecular function GO:0065009 217 0.015
regulation of cell development GO:0060284 215 0.015
proteolysis GO:0006508 192 0.015
androgen metabolic process GO:0008209 1 0.015
regulation of protein localization GO:0032880 76 0.015
multicellular organism growth GO:0035264 46 0.015
regulation of protein complex assembly GO:0043254 42 0.014
membrane budding GO:0006900 4 0.014
negative regulation of signal transduction GO:0009968 206 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
photoreceptor cell development GO:0042461 96 0.014
regulation of apoptotic process GO:0042981 130 0.014
response to organic substance GO:0010033 284 0.014
regulation of neurogenesis GO:0050767 158 0.014
central nervous system development GO:0007417 201 0.014
brain development GO:0007420 120 0.014
regulation of tor signaling GO:0032006 21 0.014
immune system development GO:0002520 57 0.014
ameboidal type cell migration GO:0001667 151 0.014
positive regulation of lyase activity GO:0051349 10 0.014
cellular hormone metabolic process GO:0034754 23 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
steroid catabolic process GO:0006706 1 0.013
protein complex disassembly GO:0043241 36 0.013
camera type eye morphogenesis GO:0048593 2 0.013
anterior posterior pattern specification GO:0009952 136 0.013
salivary gland development GO:0007431 162 0.013
centrosome organization GO:0051297 163 0.013
protein transport GO:0015031 155 0.013
ribonucleoside monophosphate catabolic process GO:0009158 39 0.013
regulation of hormone levels GO:0010817 40 0.013
organic substance catabolic process GO:1901575 308 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
striated muscle contraction GO:0006941 5 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
learning GO:0007612 75 0.013
cell cycle checkpoint GO:0000075 95 0.013
gland development GO:0048732 191 0.012
cellular response to external stimulus GO:0071496 66 0.012
regulation of blood circulation GO:1903522 21 0.012
small molecule metabolic process GO:0044281 305 0.012
response to external biotic stimulus GO:0043207 293 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
regulation of muscle contraction GO:0006937 5 0.012
negative regulation of ras protein signal transduction GO:0046580 13 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
aging GO:0007568 143 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
response to hormone GO:0009725 45 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
arf protein signal transduction GO:0032011 2 0.012
establishment of planar polarity GO:0001736 87 0.012
skeletal muscle fiber development GO:0048741 3 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
phosphatidylcholine metabolic process GO:0046470 3 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
cellular ketone metabolic process GO:0042180 24 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
muscle contraction GO:0006936 13 0.011
tissue migration GO:0090130 155 0.011
nucleoside catabolic process GO:0009164 112 0.011
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.011
cellular biogenic amine metabolic process GO:0006576 9 0.011
response to lipopolysaccharide GO:0032496 4 0.011
detection of external stimulus GO:0009581 66 0.011
negative regulation of nervous system development GO:0051961 92 0.011
positive regulation of cell motility GO:2000147 3 0.011
axon guidance GO:0007411 233 0.011
nuclear division GO:0000280 332 0.011
positive regulation of cell migration GO:0030335 2 0.011
wing disc pattern formation GO:0035222 66 0.011
retina development in camera type eye GO:0060041 4 0.011
development of primary sexual characteristics GO:0045137 50 0.011
protein adp ribosylation GO:0006471 4 0.011
actin filament depolymerization GO:0030042 5 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
regulation of protein transport GO:0051223 57 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
rna transport GO:0050658 46 0.010
reactive oxygen species metabolic process GO:0072593 22 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
organophosphate biosynthetic process GO:0090407 46 0.010
cellular response to sterol depletion GO:0071501 3 0.010
female meiotic division GO:0007143 70 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
cellular pigmentation GO:0033059 12 0.010
regulation of actin nucleation GO:0051125 3 0.010
micropyle formation GO:0046844 4 0.010

Sh3beta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.111
muscular disease DOID:0080000 0 0.111
heart disease DOID:114 0 0.111
cardiomyopathy DOID:0050700 0 0.111
disease of anatomical entity DOID:7 0 0.111
cardiovascular system disease DOID:1287 0 0.111
musculoskeletal system disease DOID:17 0 0.111
muscle tissue disease DOID:66 0 0.111
disease of cellular proliferation DOID:14566 0 0.039
disease of metabolism DOID:0014667 0 0.032
lipid metabolism disorder DOID:3146 0 0.032
inherited metabolic disorder DOID:655 0 0.032
intrinsic cardiomyopathy DOID:0060036 0 0.022
nervous system disease DOID:863 0 0.010
neuromuscular disease DOID:440 0 0.010
neuropathy DOID:870 0 0.010