Drosophila melanogaster

0 known processes

spz4 (Dmel_CG14928)

spatzle 4

(Aliases: CT34755,Spz4,Dmel\CG14928,CG14928)

spz4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sterol homeostasis GO:0055092 4 0.070
organic acid metabolic process GO:0006082 103 0.065
catabolic process GO:0009056 409 0.051
cholesterol homeostasis GO:0042632 3 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
post embryonic appendage morphogenesis GO:0035120 385 0.045
small molecule metabolic process GO:0044281 305 0.045
organic substance catabolic process GO:1901575 308 0.042
carboxylic acid metabolic process GO:0019752 92 0.040
wing disc morphogenesis GO:0007472 344 0.040
endocytosis GO:0006897 310 0.040
oxoacid metabolic process GO:0043436 103 0.039
cellular catabolic process GO:0044248 372 0.039
cellular amino acid metabolic process GO:0006520 61 0.039
negative regulation of response to stimulus GO:0048585 258 0.038
organonitrogen compound metabolic process GO:1901564 318 0.036
appendage morphogenesis GO:0035107 397 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.035
appendage development GO:0048736 401 0.035
homeostatic process GO:0042592 199 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
single organism catabolic process GO:0044712 228 0.033
g protein coupled receptor signaling pathway GO:0007186 136 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
cellular amine metabolic process GO:0044106 12 0.032
chemical homeostasis GO:0048878 92 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
response to organic substance GO:0010033 284 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.027
cell motility GO:0048870 251 0.027
phagocytosis GO:0006909 215 0.027
vesicle mediated transport GO:0016192 381 0.026
defense response GO:0006952 300 0.026
regulation of localization GO:0032879 275 0.024
organic hydroxy compound metabolic process GO:1901615 83 0.024
innate immune response GO:0045087 144 0.024
cell proliferation GO:0008283 299 0.024
negative regulation of gene expression GO:0010629 387 0.024
amine metabolic process GO:0009308 12 0.024
developmental growth GO:0048589 280 0.024
phospholipid homeostasis GO:0055091 1 0.024
organophosphate metabolic process GO:0019637 195 0.024
positive regulation of signaling GO:0023056 243 0.023
ethanolamine containing compound metabolic process GO:0042439 4 0.023
regulation of molecular function GO:0065009 217 0.023
neuropeptide signaling pathway GO:0007218 45 0.023
sulfur compound metabolic process GO:0006790 59 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
positive regulation of cell communication GO:0010647 250 0.023
actin filament organization GO:0007015 126 0.022
response to lipopolysaccharide GO:0032496 4 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
vitamin biosynthetic process GO:0009110 1 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
cellular lipid metabolic process GO:0044255 83 0.021
programmed cell death GO:0012501 257 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
chaeta development GO:0022416 97 0.021
organic substance transport GO:0071702 257 0.021
gland development GO:0048732 191 0.021
regulation of transport GO:0051049 181 0.021
triglyceride biosynthetic process GO:0019432 2 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
anion homeostasis GO:0055081 3 0.020
immune system process GO:0002376 347 0.020
cell death GO:0008219 279 0.020
organelle fission GO:0048285 340 0.020
regulation of nervous system development GO:0051960 248 0.020
regulation of response to stress GO:0080134 200 0.020
positive regulation of gene expression GO:0010628 290 0.020
acylglycerol catabolic process GO:0046464 3 0.020
body morphogenesis GO:0010171 2 0.020
localization of cell GO:0051674 257 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
lipid metabolic process GO:0006629 121 0.019
response to biotic stimulus GO:0009607 294 0.019
forebrain development GO:0030900 2 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
regulation of catalytic activity GO:0050790 185 0.019
regulation of protein metabolic process GO:0051246 256 0.019
macromolecular complex assembly GO:0065003 256 0.018
regulation of organelle organization GO:0033043 196 0.018
cell division GO:0051301 248 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
response to oxygen containing compound GO:1901700 200 0.018
neutral lipid biosynthetic process GO:0046460 2 0.018
synaptic transmission GO:0007268 288 0.018
regulation of immune system process GO:0002682 176 0.018
phosphatidylethanolamine metabolic process GO:0046337 1 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
multicellular organismal aging GO:0010259 140 0.018
response to other organism GO:0051707 293 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
lateral inhibition GO:0046331 206 0.017
establishment of localization in cell GO:0051649 402 0.017
response to mercury ion GO:0046689 3 0.017
gene silencing GO:0016458 138 0.017
androgen metabolic process GO:0008209 1 0.017
acylglycerol biosynthetic process GO:0046463 2 0.017
cell migration GO:0016477 238 0.017
immune response activating signal transduction GO:0002757 2 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
negative regulation of cell communication GO:0010648 223 0.017
positive regulation of lipid storage GO:0010884 4 0.017
negative regulation of signaling GO:0023057 219 0.016
immune response GO:0006955 246 0.016
regulation of developmental growth GO:0048638 174 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
intracellular signal transduction GO:0035556 300 0.016
positive regulation of signal transduction GO:0009967 223 0.016
regulation of gene silencing GO:0060968 63 0.016
response to external biotic stimulus GO:0043207 293 0.016
regulation of cell cycle process GO:0010564 181 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
wound healing GO:0042060 75 0.016
locomotory behavior GO:0007626 176 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
telencephalon development GO:0021537 2 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
estrogen metabolic process GO:0008210 1 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regionalization GO:0003002 416 0.016
camera type eye development GO:0043010 4 0.016
alditol phosphate metabolic process GO:0052646 2 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
cellular modified amino acid metabolic process GO:0006575 45 0.016
negative regulation of gene expression epigenetic GO:0045814 77 0.015
organophosphate catabolic process GO:0046434 112 0.015
vitamin metabolic process GO:0006766 2 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
regulation of lipid transport GO:0032368 3 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
lipid homeostasis GO:0055088 33 0.015
regulation of cell cycle GO:0051726 291 0.015
sensory organ morphogenesis GO:0090596 260 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
actin cytoskeleton organization GO:0030036 206 0.015
nuclear division GO:0000280 332 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
skin development GO:0043588 65 0.015
oxidation reduction process GO:0055114 123 0.015
response to abiotic stimulus GO:0009628 341 0.015
regulation of hydrolase activity GO:0051336 97 0.015
cholesterol transport GO:0030301 2 0.014
actin filament based process GO:0030029 220 0.014
kidney development GO:0001822 3 0.014
negative regulation of signal transduction GO:0009968 206 0.014
neutral lipid catabolic process GO:0046461 3 0.014
triglyceride catabolic process GO:0019433 3 0.014
exocrine system development GO:0035272 162 0.014
phosphorylation GO:0016310 294 0.014
segmentation GO:0035282 207 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
epithelial cell development GO:0002064 274 0.014
response to organic cyclic compound GO:0014070 89 0.014
response to wounding GO:0009611 94 0.014
aromatic compound catabolic process GO:0019439 166 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
growth GO:0040007 359 0.014
organelle assembly GO:0070925 198 0.014
mitotic nuclear division GO:0007067 213 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
positive regulation of cell migration GO:0030335 2 0.014
protein localization GO:0008104 284 0.014
protein modification process GO:0036211 438 0.014
heterocycle catabolic process GO:0046700 166 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
response to copper ion GO:0046688 4 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
positive regulation of cell motility GO:2000147 3 0.013
compound eye development GO:0048749 307 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
death GO:0016265 284 0.013
retina development in camera type eye GO:0060041 4 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
protein transport GO:0015031 155 0.013
regulation of sequestering of triglyceride GO:0010889 3 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
rhythmic process GO:0048511 106 0.013
chemotaxis GO:0006935 249 0.013
salivary gland morphogenesis GO:0007435 145 0.013
cilium organization GO:0044782 41 0.013
regulation of behavior GO:0050795 75 0.013
regulation of immune response GO:0050776 118 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
lipid localization GO:0010876 54 0.013
open tracheal system development GO:0007424 204 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
polyol biosynthetic process GO:0046173 3 0.013
epithelial cell differentiation GO:0030855 322 0.013
rna processing GO:0006396 147 0.013
glycerolipid catabolic process GO:0046503 3 0.013
thioester metabolic process GO:0035383 3 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
nucleotide metabolic process GO:0009117 161 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
cellular ketone metabolic process GO:0042180 24 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
response to organophosphorus GO:0046683 2 0.012
establishment of protein localization GO:0045184 163 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of programmed cell death GO:0043067 152 0.012
response to nitrogen compound GO:1901698 90 0.012
ras protein signal transduction GO:0007265 88 0.012
regulation of cell development GO:0060284 215 0.012
gland morphogenesis GO:0022612 145 0.012
single organism intracellular transport GO:1902582 207 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
response to monosaccharide GO:0034284 4 0.012
neuron recognition GO:0008038 101 0.012
hindbrain development GO:0030902 2 0.012
taxis GO:0042330 304 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
dephosphorylation GO:0016311 51 0.012
regulation of sterol transport GO:0032371 1 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.012
chromosome segregation GO:0007059 157 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
multi organism behavior GO:0051705 175 0.012
golgi organization GO:0007030 66 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
camera type eye morphogenesis GO:0048593 2 0.011
negative regulation of developmental process GO:0051093 201 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
larval behavior GO:0030537 42 0.011
defense response to other organism GO:0098542 225 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
protein complex assembly GO:0006461 200 0.011
response to endogenous stimulus GO:0009719 119 0.011
fatty acid metabolic process GO:0006631 20 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
response to nutrient levels GO:0031667 114 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
response to extracellular stimulus GO:0009991 116 0.011
histolysis GO:0007559 102 0.011
synapse assembly GO:0007416 143 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
protein complex biogenesis GO:0070271 201 0.011
regulation of synaptic transmission GO:0050804 69 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
regulation of cell proliferation GO:0042127 163 0.011
purine containing compound metabolic process GO:0072521 155 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
humoral immune response GO:0006959 117 0.011
acetylcholine metabolic process GO:0008291 2 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
chromosome organization GO:0051276 360 0.011
transmembrane transport GO:0055085 139 0.011
positive regulation of sequestering of triglyceride GO:0010890 1 0.011
cellular amide metabolic process GO:0043603 80 0.011
respiratory system development GO:0060541 213 0.011
steroid catabolic process GO:0006706 1 0.011
carbohydrate metabolic process GO:0005975 82 0.011
regulation of catabolic process GO:0009894 170 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
negative regulation of homeostatic process GO:0032845 2 0.010
autophagy GO:0006914 108 0.010
determination of adult lifespan GO:0008340 137 0.010
compound eye morphogenesis GO:0001745 249 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
chromatin silencing GO:0006342 76 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
positive regulation of molecular function GO:0044093 136 0.010
behavioral response to pain GO:0048266 3 0.010
neuron projection guidance GO:0097485 241 0.010
tube morphogenesis GO:0035239 191 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
inorganic cation transmembrane transport GO:0098662 61 0.010
phosphatidic acid metabolic process GO:0046473 1 0.010
cilium assembly GO:0042384 38 0.010
regulation of anatomical structure size GO:0090066 163 0.010
regulation of cell differentiation GO:0045595 302 0.010
cell recognition GO:0008037 102 0.010
autophagic cell death GO:0048102 83 0.010
cellular response to organic substance GO:0071310 132 0.010
regulation of multi organism process GO:0043900 131 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
protein phosphorylation GO:0006468 169 0.010
cellular protein modification process GO:0006464 438 0.010
regulation of growth GO:0040008 233 0.010
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.010
nucleoside catabolic process GO:0009164 112 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
cuticle development GO:0042335 86 0.010
mapk cascade GO:0000165 107 0.010

spz4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.034
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.020
sensory system disease DOID:0050155 0 0.019
carbohydrate metabolism disease DOID:0050013 0 0.016
glucose metabolism disease DOID:4194 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
familial hypertriglyceridemia DOID:0050527 0 0.015
lipid metabolism disorder DOID:3146 0 0.015
familial hyperlipidemia DOID:1168 0 0.015
familial combined hyperlipidemia DOID:13809 0 0.015
diabetes mellitus DOID:9351 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
urinary system disease DOID:18 0 0.013
hair disease DOID:421 0 0.013
integumentary system disease DOID:16 0 0.013
hypotrichosis DOID:4535 0 0.012
cardiovascular system disease DOID:1287 0 0.012
renal tubular transport disease DOID:447 0 0.011
kidney disease DOID:557 0 0.011
disease of cellular proliferation DOID:14566 0 0.010