Drosophila melanogaster

0 known processes

Yp1 (Dmel_CG2985)

Yolk protein 1

(Aliases: VIT1Dm,YP1,YP-1,fs(1)1163,YP[[1]],DmYP1,VG1,CG2985,yp1,yp,YP,yp-1,YPI,Dmel\CG2985,fs(1)A1163)

Yp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phospholipid homeostasis GO:0055091 1 0.998
Human
lipid homeostasis GO:0055088 33 0.716
Human
phosphatidylethanolamine metabolic process GO:0046337 1 0.677
triglyceride homeostasis GO:0070328 18 0.671
Human
anion homeostasis GO:0055081 3 0.666
Human
neutral lipid biosynthetic process GO:0046460 2 0.621
Rat
sterol homeostasis GO:0055092 4 0.571
Human
acylglycerol homeostasis GO:0055090 19 0.477
Human
triglyceride biosynthetic process GO:0019432 2 0.456
Rat
cellular catabolic process GO:0044248 372 0.448
Human
acylglycerol biosynthetic process GO:0046463 2 0.433
Rat
triglyceride catabolic process GO:0019433 3 0.416
Human
glycerolipid catabolic process GO:0046503 3 0.402
Human
regulation of sequestering of triglyceride GO:0010889 3 0.398
neutral lipid catabolic process GO:0046461 3 0.370
Human
acylglycerol catabolic process GO:0046464 3 0.352
Human
positive regulation of lipid storage GO:0010884 4 0.331
fatty acid metabolic process GO:0006631 20 0.317
Human
lipid catabolic process GO:0016042 21 0.314
Human Rat
cholesterol homeostasis GO:0042632 3 0.305
Human
cholesterol transport GO:0030301 2 0.288
Human
organic substance catabolic process GO:1901575 308 0.282
Human Rat
regulation of lipid storage GO:0010883 22 0.270
response to oxygen containing compound GO:1901700 200 0.251
ethanolamine containing compound metabolic process GO:0042439 4 0.246
regulation of sterol transport GO:0032371 1 0.242
Human
catabolic process GO:0009056 409 0.236
Human Rat
phosphatidic acid metabolic process GO:0046473 1 0.224
cellular lipid catabolic process GO:0044242 16 0.223
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.215
cellular response to chemical stimulus GO:0070887 199 0.201
organic substance transport GO:0071702 257 0.193
Human
oxoacid metabolic process GO:0043436 103 0.186
Human
amine metabolic process GO:0009308 12 0.169
establishment of localization in cell GO:0051649 402 0.168
protein transport GO:0015031 155 0.165
regulation of lipid transport GO:0032368 3 0.157
Human
glycerolipid metabolic process GO:0046486 34 0.155
Human Rat
protein localization GO:0008104 284 0.142
cellular amine metabolic process GO:0044106 12 0.139
imaginal disc derived appendage development GO:0048737 399 0.136
immune system process GO:0002376 347 0.128
acylglycerol metabolic process GO:0006639 12 0.128
Human Rat
regulation of cholesterol transport GO:0032374 1 0.119
Human
homeostatic process GO:0042592 199 0.117
Human
intracellular transport GO:0046907 228 0.098
microtubule organizing center organization GO:0031023 168 0.097
cell proliferation GO:0008283 299 0.097
appendage morphogenesis GO:0035107 397 0.094
response to cold GO:0009409 13 0.093
Rat
lipid metabolic process GO:0006629 121 0.093
Human Rat
positive regulation of sequestering of triglyceride GO:0010890 1 0.090
post embryonic appendage morphogenesis GO:0035120 385 0.089
endocytosis GO:0006897 310 0.088
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.086
circadian rhythm GO:0007623 105 0.083
intracellular protein transport GO:0006886 104 0.082
regulation of catabolic process GO:0009894 170 0.081
appendage development GO:0048736 401 0.080
organophosphate metabolic process GO:0019637 195 0.078
triglyceride metabolic process GO:0006641 12 0.077
Human Rat
lipid localization GO:0010876 54 0.076
Human
wing disc morphogenesis GO:0007472 344 0.075
protein import GO:0017038 55 0.075
cellular response to organic substance GO:0071310 132 0.074
carboxylic acid metabolic process GO:0019752 92 0.073
Human
response to organonitrogen compound GO:0010243 75 0.073
small molecule metabolic process GO:0044281 305 0.071
Human
regulation of cell cycle GO:0051726 291 0.071
response to abiotic stimulus GO:0009628 341 0.071
Rat
proteolysis GO:0006508 192 0.069
cellular response to endogenous stimulus GO:0071495 80 0.065
establishment of protein localization GO:0045184 163 0.065
cellular protein localization GO:0034613 160 0.064
single organism cellular localization GO:1902580 180 0.063
regulation of catalytic activity GO:0050790 185 0.060
regulation of localization GO:0032879 275 0.058
Human
chemical homeostasis GO:0048878 92 0.058
Human
positive regulation of transport GO:0051050 92 0.056
Human
cellular response to hormone stimulus GO:0032870 44 0.055
regulation of multicellular organismal development GO:2000026 414 0.055
regulation of molecular function GO:0065009 217 0.054
positive regulation of molecular function GO:0044093 136 0.054
establishment of protein localization to organelle GO:0072594 62 0.053
single organism intracellular transport GO:1902582 207 0.053
cellular lipid metabolic process GO:0044255 83 0.053
Human Rat
protein complex biogenesis GO:0070271 201 0.052
response to organic substance GO:0010033 284 0.052
alditol phosphate metabolic process GO:0052646 2 0.051
developmental growth GO:0048589 280 0.051
cellular macromolecule localization GO:0070727 220 0.050
dna metabolic process GO:0006259 227 0.049
defense response to other organism GO:0098542 225 0.048
protein complex assembly GO:0006461 200 0.046
growth GO:0040007 359 0.046
regulation of phosphate metabolic process GO:0019220 210 0.046
monocarboxylic acid metabolic process GO:0032787 29 0.045
Human
hematopoietic or lymphoid organ development GO:0048534 57 0.044
single organism catabolic process GO:0044712 228 0.044
Human Rat
dna conformation change GO:0071103 105 0.044
positive regulation of cellular catabolic process GO:0031331 95 0.044
protein transmembrane transport GO:0071806 4 0.041
generation of precursor metabolites and energy GO:0006091 42 0.041
protein targeting GO:0006605 64 0.039
organic acid metabolic process GO:0006082 103 0.038
Human
single organism biosynthetic process GO:0044711 206 0.038
Human Rat
macromolecular complex assembly GO:0065003 256 0.037
single organism behavior GO:0044708 391 0.037
positive regulation of catabolic process GO:0009896 105 0.037
response to temperature stimulus GO:0009266 106 0.036
Rat
response to nitrogen compound GO:1901698 90 0.035
regulation of protein metabolic process GO:0051246 256 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.035
nuclear transport GO:0051169 72 0.035
vesicle mediated transport GO:0016192 381 0.034
Fly
negative regulation of cell proliferation GO:0008285 69 0.034
regulation of transport GO:0051049 181 0.034
Human
regulation of cell cycle phase transition GO:1901987 130 0.034
regulation of cellular amine metabolic process GO:0033238 3 0.033
regulation of mitotic cell cycle GO:0007346 190 0.032
regulation of mitotic cell cycle phase transition GO:1901990 130 0.032
hemopoiesis GO:0030097 46 0.031
intracellular protein transmembrane transport GO:0065002 4 0.031
fatty acid biosynthetic process GO:0006633 6 0.031
Human
organonitrogen compound metabolic process GO:1901564 318 0.031
centrosome organization GO:0051297 163 0.031
hematopoietic progenitor cell differentiation GO:0002244 1 0.030
lipid biosynthetic process GO:0008610 46 0.030
Human Rat
oxidation reduction process GO:0055114 123 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.028
imaginal disc growth GO:0007446 37 0.028
rhythmic process GO:0048511 106 0.028
regulation of protein transport GO:0051223 57 0.027
positive regulation of signal transduction GO:0009967 223 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
positive regulation of catalytic activity GO:0043085 118 0.027
cellular response to oxygen containing compound GO:1901701 79 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
eggshell formation GO:0030703 105 0.026
organic hydroxy compound metabolic process GO:1901615 83 0.026
compound eye development GO:0048749 307 0.025
maintenance of location GO:0051235 73 0.025
glycoprotein biosynthetic process GO:0009101 41 0.025
adult behavior GO:0030534 137 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
eggshell chorion assembly GO:0007306 66 0.025
organophosphate catabolic process GO:0046434 112 0.025
regulation of growth GO:0040008 233 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
cytoplasmic transport GO:0016482 130 0.023
ion homeostasis GO:0050801 55 0.023
Human
small molecule biosynthetic process GO:0044283 37 0.023
Human
positive regulation of multicellular organismal process GO:0051240 143 0.022
Human
negative regulation of developmental process GO:0051093 201 0.022
protein modification process GO:0036211 438 0.022
chorion containing eggshell formation GO:0007304 105 0.022
protein localization to organelle GO:0033365 82 0.022
cellular response to ethanol GO:0071361 4 0.021
neuropeptide signaling pathway GO:0007218 45 0.021
centrosome cycle GO:0007098 137 0.021
sulfur compound biosynthetic process GO:0044272 16 0.021
response to endogenous stimulus GO:0009719 119 0.021
response to peptide hormone GO:0043434 29 0.021
response to copper ion GO:0046688 4 0.021
organelle fission GO:0048285 340 0.020
cellular ketone metabolic process GO:0042180 24 0.020
protein catabolic process GO:0030163 101 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.019
regulation of protein modification process GO:0031399 112 0.019
positive regulation of cell communication GO:0010647 250 0.019
acetaldehyde metabolic process GO:0006117 5 0.019
positive regulation of mitotic cell cycle GO:0045931 34 0.019
regulation of cell cycle process GO:0010564 181 0.019
cell cycle phase transition GO:0044770 140 0.019
positive regulation of signaling GO:0023056 243 0.018
intracellular protein transmembrane import GO:0044743 4 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.018
negative regulation of cell communication GO:0010648 223 0.018
phosphorylation GO:0016310 294 0.018
immune system development GO:0002520 57 0.017
nucleocytoplasmic transport GO:0006913 72 0.017
cellular protein catabolic process GO:0044257 83 0.017
single organism nuclear import GO:1902593 51 0.017
protein targeting to nucleus GO:0044744 51 0.017
death GO:0016265 284 0.017
monocarboxylic acid transport GO:0015718 3 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
transmembrane transport GO:0055085 139 0.016
nad metabolic process GO:0019674 1 0.016
phagocytosis GO:0006909 215 0.016
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
endomembrane system organization GO:0010256 119 0.015
defense response to fungus GO:0050832 48 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
sensory organ morphogenesis GO:0090596 260 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
phosphatidylcholine metabolic process GO:0046470 3 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
regulation of protein localization GO:0032880 76 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.014
spindle organization GO:0007051 253 0.014
body morphogenesis GO:0010171 2 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.014
response to nutrient levels GO:0031667 114 0.014
macromolecule catabolic process GO:0009057 161 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
response to carbohydrate GO:0009743 15 0.014
response to calcium ion GO:0051592 1 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.013
peptidyl tyrosine modification GO:0018212 24 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
rna processing GO:0006396 147 0.013
dna dependent dna replication GO:0006261 17 0.013
regulation of cellular localization GO:0060341 136 0.013
mitochondrion organization GO:0007005 65 0.013
nuclear import GO:0051170 51 0.013
protein import into nucleus GO:0006606 51 0.013
ion transport GO:0006811 145 0.013
organic acid biosynthetic process GO:0016053 15 0.012
Human
alcohol metabolic process GO:0006066 25 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
protein localization to nucleus GO:0034504 55 0.012
mitotic nuclear division GO:0007067 213 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of cell differentiation GO:0045595 302 0.012
compound eye morphogenesis GO:0001745 249 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
melanotic encapsulation of foreign target GO:0035011 30 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
organic anion transport GO:0015711 28 0.012
dorsal appendage formation GO:0046843 47 0.012
encapsulation of foreign target GO:0035010 38 0.011
dna replication GO:0006260 48 0.011
cellular protein modification process GO:0006464 438 0.011
carboxylic acid biosynthetic process GO:0046394 15 0.011
Human
regulation of phosphorylation GO:0042325 147 0.011
immune effector process GO:0002252 98 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
wnt signaling pathway GO:0016055 98 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
regulation of response to stress GO:0080134 200 0.011
kidney development GO:0001822 3 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
intracellular signal transduction GO:0035556 300 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
centrosome duplication GO:0051298 121 0.011
regulation of immune response GO:0050776 118 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
regulation of cell proliferation GO:0042127 163 0.010
rna localization GO:0006403 115 0.010
purine containing compound metabolic process GO:0072521 155 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
phospholipid metabolic process GO:0006644 23 0.010
detection of chemical stimulus GO:0009593 93 0.010
mrna processing GO:0006397 104 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
protein phosphorylation GO:0006468 169 0.010

Yp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 1.000
Human
familial hypertriglyceridemia DOID:0050527 0 1.000
Human
lipid metabolism disorder DOID:3146 0 1.000
Human
inherited metabolic disorder DOID:655 0 1.000
Human
hair disease DOID:421 0 0.987
Human
disease of anatomical entity DOID:7 0 0.987
Human
integumentary system disease DOID:16 0 0.987
Human
hypotrichosis DOID:4535 0 0.987
Human
familial hyperlipidemia DOID:1168 0 0.956
familial combined hyperlipidemia DOID:13809 0 0.903
diabetes mellitus DOID:9351 0 0.493
Human
carbohydrate metabolism disease DOID:0050013 0 0.493
Human
glucose metabolism disease DOID:4194 0 0.493
Human
acquired metabolic disease DOID:0060158 0 0.493
Human
familial lipoprotein lipase deficiency DOID:14118 0 0.416
type 2 diabetes mellitus DOID:9352 0 0.332
Human
nervous system disease DOID:863 0 0.027
bone disease DOID:0080001 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012