Drosophila melanogaster

18 known processes

KaiRIA (Dmel_CG18039)

CG18039 gene product from transcript CG18039-RA

(Aliases: CG18039,CT13538,DKaiR-IA,GluR-IID,GluRIID,Dro GluRIA,GluRIA,Dmel\CG18039,brec,Kai-RIA)

KaiRIA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rhythmic excitation GO:0043179 1 0.979
synaptic transmission glutamatergic GO:0035249 7 0.909
Fly
synapse organization GO:0050808 196 0.868
Fly
synaptic transmission GO:0007268 288 0.851
neurotransmitter secretion GO:0007269 35 0.845
Fly
signal release GO:0023061 49 0.739
Fly
regulation of synaptic activity GO:0060025 9 0.725
Fly
regulation of neurotransmitter secretion GO:0046928 14 0.711
Fly
neuromuscular synaptic transmission GO:0007274 67 0.672
neurotransmitter transport GO:0006836 37 0.635
Fly
regulation of synapse structure and activity GO:0050803 128 0.619
Fly
neuron neuron synaptic transmission GO:0007270 14 0.599
Fly
regulation of neurotransmitter levels GO:0001505 38 0.536
Fly
regulation of neuromuscular synaptic transmission GO:1900073 15 0.488
Fly
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.471
Fly
secretion GO:0046903 109 0.460
Fly
ion transmembrane transport GO:0034220 122 0.373
Fly
positive regulation of neuromuscular synaptic transmission GO:1900075 4 0.225
Fly
synaptic vesicle transport GO:0048489 50 0.219
ion transport GO:0006811 145 0.176
Fly
regulation of cellular localization GO:0060341 136 0.175
Fly
developmental maturation GO:0021700 172 0.174
Fly
regulation of neurotransmitter transport GO:0051588 14 0.165
Fly
positive regulation of synaptic transmission GO:0050806 15 0.162
Fly
cation transport GO:0006812 110 0.154
Fly
vesicle mediated transport GO:0016192 381 0.124
establishment of localization in cell GO:0051649 402 0.123
Fly
transmembrane transport GO:0055085 139 0.118
Fly
regulation of synaptic transmission glutamatergic GO:0051966 5 0.105
Fly
mechanosensory behavior GO:0007638 12 0.104
protein localization GO:0008104 284 0.097
Fly
establishment of protein localization GO:0045184 163 0.096
Fly
growth GO:0040007 359 0.090
axon development GO:0061564 297 0.087
mating GO:0007618 120 0.078
synapse maturation GO:0060074 7 0.075
Fly
establishment of organelle localization GO:0051656 122 0.072
secretion by cell GO:0032940 101 0.072
Fly
regulation of secretion by cell GO:1903530 39 0.069
Fly
regulation of synaptic transmission GO:0050804 69 0.067
positive regulation of cell communication GO:0010647 250 0.067
Fly
response to mechanical stimulus GO:0009612 28 0.066
response to abiotic stimulus GO:0009628 341 0.064
synaptic vesicle endocytosis GO:0048488 28 0.064
multi organism behavior GO:0051705 175 0.062
synaptic vesicle exocytosis GO:0016079 16 0.061
organelle fusion GO:0048284 46 0.059
reproductive behavior GO:0019098 122 0.058
multi multicellular organism process GO:0044706 123 0.057
regulation of transport GO:0051049 181 0.052
Fly
potassium ion transport GO:0006813 20 0.052
establishment of vesicle localization GO:0051650 51 0.048
organonitrogen compound metabolic process GO:1901564 318 0.047
body morphogenesis GO:0010171 2 0.046
cellular protein modification process GO:0006464 438 0.046
endocytosis GO:0006897 310 0.046
metal ion transport GO:0030001 74 0.046
synaptic vesicle recycling GO:0036465 28 0.045
neuromuscular junction development GO:0007528 149 0.045
negative regulation of cellular metabolic process GO:0031324 382 0.044
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.043
regulation of localization GO:0032879 275 0.043
Fly
rhythmic synaptic transmission GO:0060024 2 0.042
regulation of cellular component biogenesis GO:0044087 201 0.042
cellular component assembly involved in morphogenesis GO:0010927 151 0.042
sensory perception of chemical stimulus GO:0007606 116 0.041
regulation of synapse assembly GO:0051963 94 0.038
phosphorylation GO:0016310 294 0.037
single organism behavior GO:0044708 391 0.037
organonitrogen compound biosynthetic process GO:1901566 117 0.034
regulation of cell cycle GO:0051726 291 0.034
exocytosis GO:0006887 28 0.032
ribonucleotide metabolic process GO:0009259 145 0.031
regulation of synaptic vesicle exocytosis GO:2000300 3 0.031
single organism cellular localization GO:1902580 180 0.031
mapk cascade GO:0000165 107 0.031
positive regulation of synapse assembly GO:0051965 29 0.031
vesicle fusion GO:0006906 19 0.031
regulation of cell cycle phase transition GO:1901987 130 0.030
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.030
multi organism reproductive behavior GO:0044705 121 0.030
positive regulation of exocytosis GO:0045921 4 0.030
multicellular organismal reproductive behavior GO:0033057 110 0.030
axis specification GO:0009798 167 0.030
cellular macromolecule localization GO:0070727 220 0.029
synaptic vesicle localization GO:0097479 53 0.029
peptide metabolic process GO:0006518 80 0.029
single organismal cell cell adhesion GO:0016337 45 0.028
organelle localization GO:0051640 148 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
positive regulation of signaling GO:0023056 243 0.028
Fly
single organism biosynthetic process GO:0044711 206 0.028
regulation of filopodium assembly GO:0051489 24 0.027
organophosphate metabolic process GO:0019637 195 0.027
g protein coupled receptor signaling pathway GO:0007186 136 0.026
vesicle organization GO:0016050 44 0.026
detection of chemical stimulus GO:0009593 93 0.026
divalent inorganic cation transport GO:0072511 30 0.026
phagocytosis GO:0006909 215 0.025
catabolic process GO:0009056 409 0.025
regulation of nucleotide biosynthetic process GO:0030808 14 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
regulation of vesicle mediated transport GO:0060627 59 0.025
single organism membrane fusion GO:0044801 42 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.024
carbohydrate derivative biosynthetic process GO:1901137 85 0.024
intracellular signal transduction GO:0035556 300 0.024
male courtship behavior GO:0008049 63 0.024
protein modification process GO:0036211 438 0.024
regulation of growth GO:0040008 233 0.023
organelle assembly GO:0070925 198 0.023
receptor clustering GO:0043113 3 0.022
membrane fusion GO:0061025 42 0.022
heart process GO:0003015 37 0.022
small molecule metabolic process GO:0044281 305 0.022
regulation of developmental growth GO:0048638 174 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
adult locomotory behavior GO:0008344 76 0.022
organic acid metabolic process GO:0006082 103 0.021
aging GO:0007568 143 0.021
sperm individualization GO:0007291 48 0.021
single organism intracellular transport GO:1902582 207 0.021
positive regulation of signal transduction GO:0009967 223 0.021
inorganic ion transmembrane transport GO:0098660 73 0.021
organic substance transport GO:0071702 257 0.021
inorganic cation transmembrane transport GO:0098662 61 0.021
regulation of response to stress GO:0080134 200 0.021
single organism membrane organization GO:0044802 93 0.020
negative regulation of signal transduction GO:0009968 206 0.020
regulation of neuron projection development GO:0010975 69 0.020
response to external biotic stimulus GO:0043207 293 0.020
calcium ion transmembrane transport GO:0070588 17 0.020
intraspecies interaction between organisms GO:0051703 4 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
regulation of exocytosis GO:0017157 6 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
cellular response to dna damage stimulus GO:0006974 223 0.019
establishment of synaptic vesicle localization GO:0097480 50 0.019
positive regulation of transport GO:0051050 92 0.019
segmentation GO:0035282 207 0.019
programmed cell death GO:0012501 257 0.019
regionalization GO:0003002 416 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
regulation of immune response GO:0050776 118 0.019
regulation of pole plasm oskar mrna localization GO:0007317 27 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
response to lipopolysaccharide GO:0032496 4 0.019
regulation of apoptotic process GO:0042981 130 0.019
sensory organ morphogenesis GO:0090596 260 0.018
actin filament based process GO:0030029 220 0.018
heterochromatin organization GO:0070828 25 0.018
negative regulation of signaling GO:0023057 219 0.018
developmental growth GO:0048589 280 0.018
synapse assembly GO:0007416 143 0.018
regulation of cell death GO:0010941 173 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
light adaption GO:0036367 3 0.018
cation transmembrane transport GO:0098655 88 0.018
protein phosphorylation GO:0006468 169 0.017
regulation of secretion GO:0051046 44 0.017
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
amine metabolic process GO:0009308 12 0.017
regulation of blood circulation GO:1903522 21 0.017
oxoacid metabolic process GO:0043436 103 0.017
apoptotic process GO:0006915 159 0.017
mitotic nuclear division GO:0007067 213 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
determination of adult lifespan GO:0008340 137 0.016
membrane organization GO:0061024 112 0.016
organic substance catabolic process GO:1901575 308 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
regulation of neurogenesis GO:0050767 158 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
rna localization GO:0006403 115 0.016
positive regulation of sequestering of triglyceride GO:0010890 1 0.016
anterior posterior axis specification GO:0009948 109 0.016
aromatic compound catabolic process GO:0019439 166 0.016
positive regulation of neurotransmitter secretion GO:0001956 2 0.015
response to organic substance GO:0010033 284 0.015
defense response GO:0006952 300 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
single organism cell adhesion GO:0098602 47 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
nitrogen compound transport GO:0071705 85 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
chromosome segregation GO:0007059 157 0.015
cellular response to monosaccharide stimulus GO:0071326 2 0.015
sarcomere organization GO:0045214 26 0.015
regulation of programmed cell death GO:0043067 152 0.015
single organism catabolic process GO:0044712 228 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
endomembrane system organization GO:0010256 119 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
positive regulation of cell migration GO:0030335 2 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
spermatid differentiation GO:0048515 114 0.014
regulation of multi organism process GO:0043900 131 0.014
dendrite development GO:0016358 204 0.014
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.014
cellular amine metabolic process GO:0044106 12 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
negative regulation of calcium ion import GO:0090281 2 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
positive regulation of cell motility GO:2000147 3 0.014
camera type eye development GO:0043010 4 0.014
regulation of lyase activity GO:0051339 14 0.013
organelle fission GO:0048285 340 0.013
carbohydrate metabolic process GO:0005975 82 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
myofibril assembly GO:0030239 36 0.013
regulation of cell development GO:0060284 215 0.013
microtubule based transport GO:0010970 42 0.013
cognition GO:0050890 141 0.013
positive regulation of growth GO:0045927 75 0.013
intracellular mrna localization GO:0008298 66 0.013
cellular catabolic process GO:0044248 372 0.013
cellular lipid metabolic process GO:0044255 83 0.013
purine containing compound metabolic process GO:0072521 155 0.013
proteolysis GO:0006508 192 0.012
muscle tissue morphogenesis GO:0060415 2 0.012
oocyte axis specification GO:0007309 108 0.012
macromolecular complex assembly GO:0065003 256 0.012
cell cycle phase transition GO:0044770 140 0.012
protein hydroxylation GO:0018126 1 0.012
oviposition GO:0018991 19 0.012
negative regulation of cell cycle GO:0045786 116 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
circadian rhythm GO:0007623 105 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
macromolecule catabolic process GO:0009057 161 0.012
protein transport GO:0015031 155 0.012
regulation of synaptic vesicle transport GO:1902803 10 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
regulation of cell maturation GO:1903429 27 0.012
somatic muscle development GO:0007525 66 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
response to endogenous stimulus GO:0009719 119 0.012
syncytium formation by plasma membrane fusion GO:0000768 43 0.012
cellular ketone metabolic process GO:0042180 24 0.012
mating behavior GO:0007617 106 0.012
tube development GO:0035295 244 0.012
nuclear division GO:0000280 332 0.012
striated muscle adaptation GO:0014888 1 0.012
muscle attachment GO:0016203 36 0.012
monovalent inorganic cation transport GO:0015672 40 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.012
compound eye morphogenesis GO:0001745 249 0.012
protein heterooligomerization GO:0051291 4 0.011
regulation of membrane potential GO:0042391 35 0.011
cell projection assembly GO:0030031 94 0.011
cell death GO:0008219 279 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
cellular homeostasis GO:0019725 80 0.011
axonogenesis GO:0007409 290 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
synaptic vesicle priming GO:0016082 1 0.011
embryonic morphogenesis GO:0048598 206 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
mrna metabolic process GO:0016071 124 0.011
biological adhesion GO:0022610 138 0.011
lipid metabolic process GO:0006629 121 0.011
embryonic pattern specification GO:0009880 174 0.011
locomotory behavior GO:0007626 176 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
compound eye development GO:0048749 307 0.011
negative regulation of organelle organization GO:0010639 56 0.011
intracellular transport GO:0046907 228 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
sensory perception of smell GO:0007608 80 0.011
regulation of organelle organization GO:0033043 196 0.011
respiratory system development GO:0060541 213 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
homeostatic process GO:0042592 199 0.011
glycoprotein metabolic process GO:0009100 41 0.011
pole plasm assembly GO:0007315 61 0.011
male gamete generation GO:0048232 201 0.011
regulation of phosphatase activity GO:0010921 3 0.011
cellular response to organic substance GO:0071310 132 0.011
multicellular organism growth GO:0035264 46 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.010
cell maturation GO:0048469 144 0.010
regulation of cellular response to stress GO:0080135 89 0.010
neurological system process GO:0050877 358 0.010
stress activated mapk cascade GO:0051403 52 0.010
pole plasm rna localization GO:0007316 52 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 10 0.010
connective tissue development GO:0061448 3 0.010
skeletal muscle adaptation GO:0043501 1 0.010
rna processing GO:0006396 147 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
embryonic axis specification GO:0000578 107 0.010
syncytium formation GO:0006949 43 0.010

KaiRIA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
cardiovascular system disease DOID:1287 0 0.047
kidney disease DOID:557 0 0.014
urinary system disease DOID:18 0 0.014
disease of metabolism DOID:0014667 0 0.013
nervous system disease DOID:863 0 0.013
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013