Drosophila melanogaster

148 known processes

atl (Dmel_CG6668)

atlastin

(Aliases: Dmel\CG6668,CG6668)

atl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.743
aging GO:0007568 143 0.663
response to abiotic stimulus GO:0009628 341 0.611
endocytosis GO:0006897 310 0.611
positive regulation of cellular component organization GO:0051130 156 0.572
organonitrogen compound metabolic process GO:1901564 318 0.566
secretion GO:0046903 109 0.548
muscle structure development GO:0061061 224 0.513
axon development GO:0061564 297 0.434
regulation of multicellular organism growth GO:0040014 40 0.399
cellular component disassembly GO:0022411 46 0.395
phagocytosis GO:0006909 215 0.375
regulation of developmental growth GO:0048638 174 0.372
regulation of growth GO:0040008 233 0.353
notch signaling pathway GO:0007219 120 0.349
small molecule metabolic process GO:0044281 305 0.323
synaptic transmission GO:0007268 288 0.304
protein modification process GO:0036211 438 0.287
response to extracellular stimulus GO:0009991 116 0.284
amine metabolic process GO:0009308 12 0.282
multicellular organismal aging GO:0010259 140 0.276
organophosphate metabolic process GO:0019637 195 0.266
chemotaxis GO:0006935 249 0.263
axon guidance GO:0007411 233 0.254
nucleotide catabolic process GO:0009166 109 0.245
developmental growth GO:0048589 280 0.242
regulation of tube size GO:0035150 46 0.235
single organism cellular localization GO:1902580 180 0.229
lipid storage GO:0019915 38 0.226
homeostatic process GO:0042592 199 0.217
cellular amine metabolic process GO:0044106 12 0.215
single organism membrane fusion GO:0044801 42 0.206
anatomical structure homeostasis GO:0060249 97 0.199
regulation of localization GO:0032879 275 0.199
synapse organization GO:0050808 196 0.192
muscle cell differentiation GO:0042692 103 0.185
secretion by cell GO:0032940 101 0.184
protein transport GO:0015031 155 0.183
macromolecular complex assembly GO:0065003 256 0.174
oxoacid metabolic process GO:0043436 103 0.172
locomotory behavior GO:0007626 176 0.165
intracellular signal transduction GO:0035556 300 0.162
ameboidal type cell migration GO:0001667 151 0.149
meiotic cell cycle process GO:1903046 132 0.147
growth GO:0040007 359 0.145
maintenance of location GO:0051235 73 0.143
striated muscle cell differentiation GO:0051146 90 0.140
regulation of synaptic transmission GO:0050804 69 0.140
regulation of nervous system development GO:0051960 248 0.139
positive regulation of developmental growth GO:0048639 62 0.136
energy taxis GO:0009453 21 0.133
retina development in camera type eye GO:0060041 4 0.129
neuron projection guidance GO:0097485 241 0.129
regulation of synapse organization GO:0050807 110 0.126
cellular response to chemical stimulus GO:0070887 199 0.126
cellular component assembly involved in morphogenesis GO:0010927 151 0.126
phototaxis GO:0042331 21 0.125
glycosyl compound catabolic process GO:1901658 112 0.125
autophagic vacuole assembly GO:0000045 2 0.123
purine nucleoside metabolic process GO:0042278 127 0.122
single organism catabolic process GO:0044712 228 0.122
establishment of vesicle localization GO:0051650 51 0.119
establishment of protein localization GO:0045184 163 0.119
response to temperature stimulus GO:0009266 106 0.118
positive regulation of cell communication GO:0010647 250 0.115
regulation of synaptic plasticity GO:0048167 14 0.112
protein localization GO:0008104 284 0.111
modification dependent macromolecule catabolic process GO:0043632 79 0.109
multicellular organism growth GO:0035264 46 0.108
determination of adult lifespan GO:0008340 137 0.107
axonogenesis GO:0007409 290 0.107
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.106
cell maturation GO:0048469 144 0.101
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.100
macromolecular complex disassembly GO:0032984 37 0.099
phosphorylation GO:0016310 294 0.098
regulation of anatomical structure morphogenesis GO:0022603 242 0.098
taxis GO:0042330 304 0.098
establishment of localization in cell GO:0051649 402 0.097
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.096
organic substance transport GO:0071702 257 0.094
regulation of notch signaling pathway GO:0008593 100 0.091
positive regulation of cell motility GO:2000147 3 0.091
ribose phosphate metabolic process GO:0019693 145 0.091
response to organic substance GO:0010033 284 0.090
organic cyclic compound catabolic process GO:1901361 168 0.090
ethanolamine containing compound metabolic process GO:0042439 4 0.089
tissue morphogenesis GO:0048729 297 0.087
purine nucleotide catabolic process GO:0006195 109 0.087
positive regulation of cell migration GO:0030335 2 0.086
positive regulation of developmental process GO:0051094 143 0.085
positive regulation of phosphorus metabolic process GO:0010562 139 0.084
organic acid metabolic process GO:0006082 103 0.084
establishment of organelle localization GO:0051656 122 0.083
regulation of intracellular signal transduction GO:1902531 236 0.082
oocyte differentiation GO:0009994 145 0.081
positive regulation of hydrolase activity GO:0051345 78 0.081
cellular macromolecule catabolic process GO:0044265 136 0.080
peptidyl amino acid modification GO:0018193 105 0.080
response to nitrogen compound GO:1901698 90 0.080
organophosphate catabolic process GO:0046434 112 0.079
endoplasmic reticulum organization GO:0007029 13 0.078
carboxylic acid metabolic process GO:0019752 92 0.077
protein targeting GO:0006605 64 0.076
regulation of cellular amino acid metabolic process GO:0006521 0 0.075
substrate adhesion dependent cell spreading GO:0034446 2 0.074
cellular protein modification process GO:0006464 438 0.073
ribonucleotide catabolic process GO:0009261 109 0.073
positive regulation of multicellular organismal process GO:0051240 143 0.072
lipid localization GO:0010876 54 0.072
nucleobase containing compound catabolic process GO:0034655 165 0.070
macromolecule catabolic process GO:0009057 161 0.070
cell substrate adhesion GO:0031589 10 0.069
establishment or maintenance of cell polarity GO:0007163 167 0.067
cellular catabolic process GO:0044248 372 0.065
regionalization GO:0003002 416 0.065
Zebrafish
glycoprotein biosynthetic process GO:0009101 41 0.065
purine nucleoside triphosphate metabolic process GO:0009144 119 0.061
positive regulation of phosphate metabolic process GO:0045937 139 0.060
single organism intracellular transport GO:1902582 207 0.060
neurological system process GO:0050877 358 0.058
heterocycle catabolic process GO:0046700 166 0.057
regulation of neurotransmitter levels GO:0001505 38 0.057
regulation of synaptic activity GO:0060025 9 0.056
intracellular protein transport GO:0006886 104 0.054
response to organophosphorus GO:0046683 2 0.054
meiotic cell cycle GO:0051321 171 0.053
inorganic cation transmembrane transport GO:0098662 61 0.053
response to mechanical stimulus GO:0009612 28 0.053
positive regulation of response to stimulus GO:0048584 323 0.053
camera type eye development GO:0043010 4 0.052
purine ribonucleotide catabolic process GO:0009154 109 0.052
synaptic growth at neuromuscular junction GO:0051124 119 0.052
regulation of synapse structure and activity GO:0050803 128 0.052
monovalent inorganic cation transport GO:0015672 40 0.051
ion homeostasis GO:0050801 55 0.050
regulation of catabolic process GO:0009894 170 0.050
embryonic axis specification GO:0000578 107 0.050
muscle tissue development GO:0060537 30 0.049
syncytium formation by plasma membrane fusion GO:0000768 43 0.049
localization of cell GO:0051674 257 0.048
membrane organization GO:0061024 112 0.048
regulation of cellular localization GO:0060341 136 0.048
single organism behavior GO:0044708 391 0.048
ribonucleoside metabolic process GO:0009119 127 0.048
regulation of protein metabolic process GO:0051246 256 0.048
cellular protein localization GO:0034613 160 0.047
actin cytoskeleton organization GO:0030036 206 0.047
muscle cell development GO:0055001 50 0.047
positive regulation of dendrite morphogenesis GO:0050775 9 0.047
response to endogenous stimulus GO:0009719 119 0.046
establishment of protein localization to organelle GO:0072594 62 0.046
cellular response to nutrient levels GO:0031669 62 0.046
proteolysis GO:0006508 192 0.045
positive regulation of signaling GO:0023056 243 0.045
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.044
positive regulation of signal transduction GO:0009967 223 0.044
glial cell differentiation GO:0010001 35 0.044
cellular protein complex disassembly GO:0043624 35 0.044
striated muscle myosin thick filament assembly GO:0071688 3 0.044
response to starvation GO:0042594 97 0.044
cell death GO:0008219 279 0.044
Worm
morphogenesis of an epithelium GO:0002009 276 0.043
oocyte development GO:0048599 124 0.043
regulation of protein localization GO:0032880 76 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.043
carbohydrate derivative metabolic process GO:1901135 217 0.043
ribonucleoside triphosphate catabolic process GO:0009203 108 0.043
nucleoside phosphate catabolic process GO:1901292 110 0.043
acetylcholine catabolic process GO:0006581 1 0.042
single organism membrane organization GO:0044802 93 0.042
ribonucleotide metabolic process GO:0009259 145 0.042
ribonucleoside catabolic process GO:0042454 112 0.042
blastoderm segmentation GO:0007350 159 0.041
modification dependent protein catabolic process GO:0019941 78 0.040
nucleoside triphosphate catabolic process GO:0009143 108 0.040
ubiquitin dependent protein catabolic process GO:0006511 78 0.040
actin filament based movement GO:0030048 26 0.040
metal ion transport GO:0030001 74 0.040
cell adhesion GO:0007155 136 0.039
oocyte construction GO:0007308 112 0.039
regulation of anatomical structure size GO:0090066 163 0.039
muscle attachment GO:0016203 36 0.039
nucleoside phosphate metabolic process GO:0006753 162 0.038
body morphogenesis GO:0010171 2 0.038
segmentation GO:0035282 207 0.038
embryo development ending in birth or egg hatching GO:0009792 152 0.038
hindbrain development GO:0030902 2 0.038
response to oxygen containing compound GO:1901700 200 0.037
regulation of phosphorylation GO:0042325 147 0.036
carbohydrate derivative biosynthetic process GO:1901137 85 0.036
glycoprotein metabolic process GO:0009100 41 0.036
purine nucleoside triphosphate catabolic process GO:0009146 108 0.036
carbohydrate metabolic process GO:0005975 82 0.036
regulation of cellular component movement GO:0051270 42 0.036
oocyte axis specification GO:0007309 108 0.035
membrane fusion GO:0061025 42 0.035
single organism cell adhesion GO:0098602 47 0.035
cytoplasmic microtubule organization GO:0031122 22 0.035
response to nutrient levels GO:0031667 114 0.035
endomembrane system organization GO:0010256 119 0.035
cellular response to organic substance GO:0071310 132 0.034
meiotic nuclear division GO:0007126 151 0.034
pigmentation GO:0043473 75 0.034
cellular response to radiation GO:0071478 52 0.033
regulation of cellular catabolic process GO:0031329 157 0.033
skeletal muscle organ development GO:0060538 48 0.033
cellular response to endogenous stimulus GO:0071495 80 0.033
cellular amino acid metabolic process GO:0006520 61 0.032
striated muscle cell development GO:0055002 50 0.032
cellular response to external stimulus GO:0071496 66 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
guanosine containing compound catabolic process GO:1901069 74 0.031
choline catabolic process GO:0042426 1 0.031
neuron recognition GO:0008038 101 0.031
regulation of protein complex disassembly GO:0043244 29 0.031
regulation of locomotion GO:0040012 42 0.031
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
peripheral nervous system development GO:0007422 52 0.031
programmed cell death GO:0012501 257 0.031
Worm
regulation of cell morphogenesis GO:0022604 163 0.031
enzyme linked receptor protein signaling pathway GO:0007167 179 0.031
Zebrafish
response to radiation GO:0009314 155 0.030
regulation of dendrite development GO:0050773 37 0.030
cellular lipid metabolic process GO:0044255 83 0.029
positive regulation of multicellular organism growth GO:0040018 21 0.029
phosphatidylinositol mediated signaling GO:0048015 4 0.029
organelle localization GO:0051640 148 0.029
lipid metabolic process GO:0006629 121 0.029
purine containing compound catabolic process GO:0072523 112 0.028
establishment of protein localization to membrane GO:0090150 11 0.028
regulation of protein modification process GO:0031399 112 0.028
cellular protein catabolic process GO:0044257 83 0.028
cellular macromolecule localization GO:0070727 220 0.027
regulation of cell cycle GO:0051726 291 0.027
glycosyl compound metabolic process GO:1901657 127 0.027
positive regulation of cellular component movement GO:0051272 11 0.026
regulation of cell migration GO:0030334 22 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
neuromuscular junction development GO:0007528 149 0.026
epithelial cell development GO:0002064 274 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
cellular response to nitrogen compound GO:1901699 51 0.025
rna transport GO:0050658 46 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
cell migration GO:0016477 238 0.025
adult locomotory behavior GO:0008344 76 0.024
ion transmembrane transport GO:0034220 122 0.024
multicellular organismal homeostasis GO:0048871 41 0.024
translation GO:0006412 69 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.023
organelle fusion GO:0048284 46 0.023
catabolic process GO:0009056 409 0.023
regulation of neurogenesis GO:0050767 158 0.023
protein complex assembly GO:0006461 200 0.023
single organism carbohydrate metabolic process GO:0044723 72 0.022
synapse assembly GO:0007416 143 0.022
regulation of secretion GO:0051046 44 0.022
carbohydrate derivative catabolic process GO:1901136 118 0.022
neurotransmitter metabolic process GO:0042133 2 0.022
aromatic compound catabolic process GO:0019439 166 0.022
biological adhesion GO:0022610 138 0.022
developmental maturation GO:0021700 172 0.022
cell recognition GO:0008037 102 0.022
regulation of lipid storage GO:0010883 22 0.022
cellular response to starvation GO:0009267 61 0.022
cellular homeostasis GO:0019725 80 0.021
regulation of transport GO:0051049 181 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
regulation of neuron differentiation GO:0045664 103 0.020
cation transport GO:0006812 110 0.020
nucleoside catabolic process GO:0009164 112 0.020
cytoplasmic transport GO:0016482 130 0.020
organic substance catabolic process GO:1901575 308 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
respiratory system development GO:0060541 213 0.020
cell motility GO:0048870 251 0.020
transmembrane transport GO:0055085 139 0.020
regulation of membrane potential GO:0042391 35 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
embryonic pattern specification GO:0009880 174 0.019
camera type eye morphogenesis GO:0048593 2 0.019
morphogenesis of a polarized epithelium GO:0001738 93 0.019
myofibril assembly GO:0030239 36 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.019
jak stat cascade GO:0007259 49 0.019
protein glycosylation GO:0006486 32 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
protein catabolic process GO:0030163 101 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
regulation of phosphatase activity GO:0010921 3 0.019
anterior posterior pattern specification GO:0009952 136 0.019
kidney development GO:0001822 3 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
cellular response to oxygen containing compound GO:1901701 79 0.018
regulation of neural precursor cell proliferation GO:2000177 35 0.018
macroautophagy GO:0016236 42 0.018
organ growth GO:0035265 56 0.018
peptidyl threonine phosphorylation GO:0018107 2 0.018
short term memory GO:0007614 19 0.018
sulfur compound metabolic process GO:0006790 59 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
peptidyl tyrosine modification GO:0018212 24 0.017
positive regulation of calcium ion transport GO:0051928 4 0.017
axon extension GO:0048675 32 0.017
larval development GO:0002164 104 0.017
regulation of protein depolymerization GO:1901879 27 0.017
positive regulation of cell development GO:0010720 61 0.017
glial cell development GO:0021782 27 0.017
death GO:0016265 284 0.017
Worm
regulation of establishment of protein localization GO:0070201 61 0.017
positive regulation of protein phosphorylation GO:0001934 34 0.017
regulation of cell adhesion GO:0030155 27 0.017
regulation of nucleotide catabolic process GO:0030811 48 0.017
regulation of programmed cell death GO:0043067 152 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
syncytium formation GO:0006949 43 0.017
positive regulation of phosphorylation GO:0042327 87 0.016
negative regulation of cell cycle GO:0045786 116 0.016
tissue homeostasis GO:0001894 36 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
cognition GO:0050890 141 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.016
regulation of neuroblast proliferation GO:1902692 34 0.016
appendage morphogenesis GO:0035107 397 0.016
brain development GO:0007420 120 0.016
acetate ester metabolic process GO:1900619 2 0.015
response to biotic stimulus GO:0009607 294 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
single organismal cell cell adhesion GO:0016337 45 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
negative regulation of developmental growth GO:0048640 64 0.015
response to metal ion GO:0010038 23 0.015
molting cycle GO:0042303 56 0.015
regulation of stress activated mapk cascade GO:0032872 41 0.015
myosin filament assembly GO:0031034 5 0.015
male gamete generation GO:0048232 201 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
calcium ion transport GO:0006816 24 0.015
septate junction assembly GO:0019991 26 0.014
exocytosis GO:0006887 28 0.014
positive regulation of neurogenesis GO:0050769 41 0.014
membrane depolarization GO:0051899 4 0.014
adult behavior GO:0030534 137 0.014
cellular response to organonitrogen compound GO:0071417 36 0.014
positive regulation of nervous system development GO:0051962 69 0.014
peptidyl tyrosine phosphorylation GO:0018108 24 0.014
gtp catabolic process GO:0006184 72 0.014
cation homeostasis GO:0055080 51 0.014
regulation of cell projection organization GO:0031344 92 0.014
positive regulation of transport GO:0051050 92 0.014
acetylcholine metabolic process GO:0008291 2 0.014
negative regulation of phosphatase activity GO:0010923 3 0.014
potassium ion transport GO:0006813 20 0.013
open tracheal system development GO:0007424 204 0.013
regulation of protein transport GO:0051223 57 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
macromolecule glycosylation GO:0043413 32 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
protein maturation GO:0051604 71 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
cell cell adhesion mediated by integrin GO:0033631 1 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
neural precursor cell proliferation GO:0061351 75 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
tube morphogenesis GO:0035239 191 0.013
response to acid chemical GO:0001101 25 0.012
tripartite regional subdivision GO:0007351 103 0.012
erbb signaling pathway GO:0038127 58 0.012
dendrite development GO:0016358 204 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
liposaccharide metabolic process GO:1903509 8 0.012
cell aging GO:0007569 2 0.012
regulation of apoptotic process GO:0042981 130 0.012
neural retina development GO:0003407 4 0.012
response to glucose GO:0009749 2 0.012
learning or memory GO:0007611 141 0.012
regulation of secretion by cell GO:1903530 39 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
response to endoplasmic reticulum stress GO:0034976 28 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
skeletal muscle fiber development GO:0048741 3 0.011
purine containing compound metabolic process GO:0072521 155 0.011
organelle assembly GO:0070925 198 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
extracellular structure organization GO:0043062 46 0.011
cation transmembrane transport GO:0098655 88 0.011
intracellular transport GO:0046907 228 0.011
defense response GO:0006952 300 0.011
positive regulation of growth GO:0045927 75 0.011
cell cell junction organization GO:0045216 55 0.011
regulation of cell differentiation GO:0045595 302 0.010
cellular response to insulin stimulus GO:0032869 28 0.010
cellular biogenic amine metabolic process GO:0006576 9 0.010
female meiotic division GO:0007143 70 0.010
regulation of cell development GO:0060284 215 0.010
response to calcium ion GO:0051592 1 0.010
negative regulation of signaling GO:0023057 219 0.010
Zebrafish
actin filament based process GO:0030029 220 0.010
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.010
negative regulation of cell death GO:0060548 81 0.010
heart development GO:0007507 82 0.010

atl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.356
nervous system disease DOID:863 0 0.045
cardiovascular system disease DOID:1287 0 0.030
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
muscular disease DOID:0080000 0 0.025
musculoskeletal system disease DOID:17 0 0.025
muscle tissue disease DOID:66 0 0.025
neuromuscular disease DOID:440 0 0.013
charcot marie tooth disease DOID:10595 0 0.013
neuropathy DOID:870 0 0.013
central nervous system disease DOID:331 0 0.012