Drosophila melanogaster

199 known processes

dl (Dmel_CG6667)

dorsal

(Aliases: CG6667,DL,dL,Dmel\CG6667,fs(2)k10816,Dl,GSd447,anon-EST:GressD7,mat(2)dorsal,d)

dl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 347 0.448
response to extracellular stimulus GO:0009991 116 0.403
humoral immune response GO:0006959 117 0.395
single organism behavior GO:0044708 391 0.385
proteolysis GO:0006508 192 0.275
response to nutrient levels GO:0031667 114 0.274
negative regulation of response to stimulus GO:0048585 258 0.262
regulation of endopeptidase activity GO:0052548 36 0.261
defense response GO:0006952 300 0.250
negative regulation of signaling GO:0023057 219 0.247
negative regulation of signal transduction GO:0009968 206 0.235
transcription from rna polymerase ii promoter GO:0006366 368 0.217
head development GO:0060322 135 0.202
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.197
positive regulation of macromolecule metabolic process GO:0010604 405 0.192
response to oxygen containing compound GO:1901700 200 0.176
behavioral response to ethanol GO:0048149 49 0.172
regulation of hydrolase activity GO:0051336 97 0.165
regulation of defense response GO:0031347 102 0.156
positive regulation of gene expression GO:0010628 290 0.149
peptide metabolic process GO:0006518 80 0.144
regulation of peptidase activity GO:0052547 39 0.142
brain development GO:0007420 120 0.141
negative regulation of cellular metabolic process GO:0031324 382 0.140
negative regulation of cell communication GO:0010648 223 0.138
defense response to bacterium GO:0042742 178 0.133
regulation of proteolysis GO:0030162 87 0.121
defense response to fungus GO:0050832 48 0.118
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.114
antimicrobial humoral response GO:0019730 99 0.111
cognition GO:0050890 141 0.111
growth GO:0040007 359 0.109
positive regulation of nucleic acid templated transcription GO:1903508 266 0.108
positive regulation of biosynthetic process GO:0009891 316 0.107
regulation of multicellular organismal development GO:2000026 414 0.105
learning or memory GO:0007611 141 0.104
negative regulation of nucleic acid templated transcription GO:1903507 240 0.103
regulation of protein metabolic process GO:0051246 256 0.102
dendrite morphogenesis GO:0048813 199 0.101
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.098
regulation of cysteine type endopeptidase activity GO:2000116 27 0.098
positive regulation of proteolysis GO:0045862 52 0.093
immune response GO:0006955 246 0.090
regionalization GO:0003002 416 0.089
neurological system process GO:0050877 358 0.088
imaginal disc derived appendage development GO:0048737 399 0.088
organic hydroxy compound metabolic process GO:1901615 83 0.086
response to starvation GO:0042594 97 0.084
regulation of immune system process GO:0002682 176 0.083
forebrain development GO:0030900 2 0.081
antibacterial humoral response GO:0019731 44 0.079
regulation of molecular function GO:0065009 217 0.079
regulation of antimicrobial peptide production GO:0002784 44 0.076
response to bacterium GO:0009617 198 0.074
carboxylic acid metabolic process GO:0019752 92 0.072
cell cell signaling involved in cell fate commitment GO:0045168 210 0.072
macromolecular complex assembly GO:0065003 256 0.070
reproductive behavior GO:0019098 122 0.069
small molecule metabolic process GO:0044281 305 0.067
response to abiotic stimulus GO:0009628 341 0.067
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.066
negative regulation of gene expression GO:0010629 387 0.065
central nervous system development GO:0007417 201 0.063
protein processing GO:0016485 68 0.063
dna metabolic process GO:0006259 227 0.062
muscle organ development GO:0007517 127 0.062
response to alcohol GO:0097305 95 0.061
response to fungus GO:0009620 50 0.060
gland development GO:0048732 191 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.058
response to ethanol GO:0045471 59 0.056
positive regulation of rna biosynthetic process GO:1902680 266 0.056
dorsal ventral pattern formation GO:0009953 133 0.056
positive regulation of cellular biosynthetic process GO:0031328 316 0.056
male gamete generation GO:0048232 201 0.055
adult behavior GO:0030534 137 0.055
dendrite development GO:0016358 204 0.055
protein catabolic process GO:0030163 101 0.054
regulation of humoral immune response GO:0002920 51 0.054
regulation of catabolic process GO:0009894 170 0.053
response to external biotic stimulus GO:0043207 293 0.050
single organism intracellular transport GO:1902582 207 0.050
response to wounding GO:0009611 94 0.049
organelle fission GO:0048285 340 0.049
protein complex assembly GO:0006461 200 0.049
protein maturation GO:0051604 71 0.048
intracellular transport GO:0046907 228 0.048
regulation of response to stress GO:0080134 200 0.048
regulation of cell death GO:0010941 173 0.048
developmental growth GO:0048589 280 0.047
protein localization to organelle GO:0033365 82 0.047
negative regulation of cell differentiation GO:0045596 143 0.047
appendage development GO:0048736 401 0.047
response to organic cyclic compound GO:0014070 89 0.046
regulation of organ morphogenesis GO:2000027 78 0.046
response to biotic stimulus GO:0009607 294 0.046
negative regulation of response to external stimulus GO:0032102 22 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.044
dna conformation change GO:0071103 105 0.044
aging GO:0007568 143 0.043
mitotic g2 m transition checkpoint GO:0044818 70 0.043
immune system development GO:0002520 57 0.043
response to organophosphorus GO:0046683 2 0.043
positive regulation of rna metabolic process GO:0051254 271 0.043
developmental growth involved in morphogenesis GO:0060560 65 0.042
regulation of cellular protein metabolic process GO:0032268 243 0.042
regulation of programmed cell death GO:0043067 152 0.040
negative regulation of endopeptidase activity GO:0010951 11 0.040
erbb signaling pathway GO:0038127 58 0.040
regulation of cell proliferation GO:0042127 163 0.039
response to lipopolysaccharide GO:0032496 4 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.039
regulation of multi organism process GO:0043900 131 0.039
mesoderm development GO:0007498 78 0.038
cell maturation GO:0048469 144 0.037
locomotory behavior GO:0007626 176 0.037
spermatogenesis GO:0007283 200 0.037
camera type eye development GO:0043010 4 0.037
defense response to gram positive bacterium GO:0050830 41 0.036
establishment of protein localization GO:0045184 163 0.036
negative regulation of multicellular organismal process GO:0051241 142 0.036
notch signaling pathway GO:0007219 120 0.036
axonogenesis GO:0007409 290 0.036
positive regulation of signaling GO:0023056 243 0.036
response to organic substance GO:0010033 284 0.036
organonitrogen compound metabolic process GO:1901564 318 0.035
mitotic nuclear division GO:0007067 213 0.035
gliogenesis GO:0042063 80 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.034
negative regulation of proteolysis GO:0045861 31 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.033
regulation of cell cycle GO:0051726 291 0.033
developmental maturation GO:0021700 172 0.033
cell cycle phase transition GO:0044770 140 0.032
cytoplasmic transport GO:0016482 130 0.032
regulation of apoptotic process GO:0042981 130 0.032
antimicrobial peptide production GO:0002775 46 0.032
biological adhesion GO:0022610 138 0.031
negative regulation of protein processing GO:0010955 31 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.031
wing disc morphogenesis GO:0007472 344 0.030
defense response to other organism GO:0098542 225 0.030
hindbrain development GO:0030902 2 0.030
antifungal humoral response GO:0019732 12 0.030
positive regulation of signal transduction GO:0009967 223 0.030
regulation of cellular amide metabolic process GO:0034248 39 0.030
negative regulation of molecular function GO:0044092 51 0.030
cellular amide metabolic process GO:0043603 80 0.030
memory GO:0007613 94 0.030
cell type specific apoptotic process GO:0097285 38 0.030
negative regulation of cellular protein metabolic process GO:0032269 85 0.029
cell proliferation GO:0008283 299 0.029
centrosome organization GO:0051297 163 0.029
macromolecule catabolic process GO:0009057 161 0.029
regulation of catalytic activity GO:0050790 185 0.029
positive regulation of developmental process GO:0051094 143 0.029
negative regulation of defense response GO:0031348 35 0.029
endosomal transport GO:0016197 44 0.029
telencephalon development GO:0021537 2 0.028
long term memory GO:0007616 62 0.028
cellular response to chemical stimulus GO:0070887 199 0.028
regulation of production of molecular mediator of immune response GO:0002700 44 0.028
homeostatic process GO:0042592 199 0.028
nucleocytoplasmic transport GO:0006913 72 0.028
cellular response to molecule of bacterial origin GO:0071219 3 0.028
establishment of localization in cell GO:0051649 402 0.027
catabolic process GO:0009056 409 0.027
axon development GO:0061564 297 0.027
negative regulation of cellular catabolic process GO:0031330 34 0.027
positive regulation of cellular component organization GO:0051130 156 0.027
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.027
negative regulation of growth GO:0045926 84 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
epidermal growth factor receptor signaling pathway GO:0007173 58 0.026
oxoacid metabolic process GO:0043436 103 0.026
regulation of immune response GO:0050776 118 0.026
negative regulation of apoptotic process GO:0043066 63 0.025
regulation of heart morphogenesis GO:2000826 3 0.025
embryonic morphogenesis GO:0048598 206 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
cell migration GO:0016477 238 0.025
organic substance catabolic process GO:1901575 308 0.025
neuron projection guidance GO:0097485 241 0.025
compound eye development GO:0048749 307 0.025
cellular response to starvation GO:0009267 61 0.024
photoreceptor cell differentiation GO:0046530 170 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
positive regulation of immune system process GO:0002684 68 0.024
regulation of cell cycle process GO:0010564 181 0.023
positive regulation of cell proliferation GO:0008284 47 0.023
regulation of notch signaling pathway GO:0008593 100 0.023
positive regulation of multi organism process GO:0043902 40 0.023
negative regulation of peptidase activity GO:0010466 11 0.023
posttranscriptional regulation of gene expression GO:0010608 145 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
response to oxidative stress GO:0006979 86 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
positive regulation of catabolic process GO:0009896 105 0.022
anatomical structure homeostasis GO:0060249 97 0.022
response to other organism GO:0051707 293 0.022
endodermal cell fate commitment GO:0001711 3 0.022
regulation of erbb signaling pathway GO:1901184 42 0.021
cellular protein localization GO:0034613 160 0.021
regulation of protein catabolic process GO:0042176 55 0.021
eye development GO:0001654 323 0.021
cellular response to biotic stimulus GO:0071216 4 0.021
protein localization GO:0008104 284 0.021
cell death GO:0008219 279 0.021
cellular protein complex assembly GO:0043623 71 0.021
positive regulation of protein metabolic process GO:0051247 128 0.020
multicellular organismal aging GO:0010259 140 0.020
single organism catabolic process GO:0044712 228 0.020
sleep GO:0030431 49 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
cellular protein modification process GO:0006464 438 0.020
regulation of cell substrate adhesion GO:0010810 2 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
negative regulation of cell cycle phase transition GO:1901988 103 0.020
regulation of nervous system development GO:0051960 248 0.020
jak stat cascade GO:0007259 49 0.020
protein transport GO:0015031 155 0.019
response to endogenous stimulus GO:0009719 119 0.019
intracellular signal transduction GO:0035556 300 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
tissue morphogenesis GO:0048729 297 0.019
organic substance transport GO:0071702 257 0.019
photoreceptor cell development GO:0042461 96 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.019
cellular response to external stimulus GO:0071496 66 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
regulation of protein processing GO:0070613 32 0.019
positive regulation of cell death GO:0010942 69 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
response to nitrogen compound GO:1901698 90 0.018
dna packaging GO:0006323 91 0.018
regulation of wnt signaling pathway GO:0030111 68 0.018
regulation of embryonic development GO:0045995 68 0.018
cellular response to organic substance GO:0071310 132 0.018
protein complex biogenesis GO:0070271 201 0.018
apoptotic process GO:0006915 159 0.017
cellular catabolic process GO:0044248 372 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
toll signaling pathway GO:0008063 25 0.017
phagocytosis GO:0006909 215 0.017
spermatid development GO:0007286 98 0.017
cellular ketone metabolic process GO:0042180 24 0.017
compound eye morphogenesis GO:0001745 249 0.017
negative regulation of cell death GO:0060548 81 0.017
death GO:0016265 284 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
glial cell differentiation GO:0010001 35 0.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.017
determination of adult lifespan GO:0008340 137 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
hematopoietic progenitor cell differentiation GO:0002244 1 0.016
positive regulation of nervous system development GO:0051962 69 0.016
positive regulation of defense response GO:0031349 59 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
synapse organization GO:0050808 196 0.016
intracellular protein transport GO:0006886 104 0.016
bmp signaling pathway GO:0030509 27 0.016
single organism cellular localization GO:1902580 180 0.016
dna damage checkpoint GO:0000077 78 0.016
hemopoiesis GO:0030097 46 0.016
cholesterol homeostasis GO:0042632 3 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
endoderm formation GO:0001706 3 0.016
cell adhesion GO:0007155 136 0.016
g protein coupled receptor signaling pathway GO:0007186 136 0.016
negative regulation of protein maturation GO:1903318 31 0.015
response to temperature stimulus GO:0009266 106 0.015
organic hydroxy compound biosynthetic process GO:1901617 21 0.015
peripheral nervous system development GO:0007422 52 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
aggressive behavior GO:0002118 63 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
rhythmic behavior GO:0007622 76 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
regulation of response to external stimulus GO:0032101 115 0.015
developmental programmed cell death GO:0010623 138 0.015
taxis GO:0042330 304 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
protein dna complex assembly GO:0065004 63 0.015
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
antibacterial peptide biosynthetic process GO:0002780 22 0.015
peptidyl tyrosine modification GO:0018212 24 0.015
nuclear transport GO:0051169 72 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
wound healing GO:0042060 75 0.014
male courtship behavior veined wing vibration GO:0016545 21 0.014
response to drug GO:0042493 17 0.014
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.014
chaeta development GO:0022416 97 0.014
immune effector process GO:0002252 98 0.014
positive regulation of cellular amide metabolic process GO:0034250 26 0.014
production of molecular mediator of immune response GO:0002440 46 0.014
positive regulation of immune response GO:0050778 63 0.014
regulation of epithelial cell differentiation GO:0030856 4 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
connective tissue development GO:0061448 3 0.014
response to purine containing compound GO:0014074 12 0.014
regulation of stress activated mapk cascade GO:0032872 41 0.014
positive regulation of cell communication GO:0010647 250 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
regulation of organelle organization GO:0033043 196 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
response to hypoxia GO:0001666 53 0.013
sensory perception of mechanical stimulus GO:0050954 72 0.013
response to reactive oxygen species GO:0000302 24 0.013
endodermal cell differentiation GO:0035987 3 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
positive regulation of mitotic cell cycle GO:0045931 34 0.013
regulation of antimicrobial humoral response GO:0002759 50 0.013
peptidyl amino acid modification GO:0018193 105 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
negative regulation of developmental process GO:0051093 201 0.013
dorsal ventral axis specification GO:0009950 66 0.013
chromosome condensation GO:0030261 41 0.013
negative regulation of erbb signaling pathway GO:1901185 29 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
vitamin biosynthetic process GO:0009110 1 0.012
peptidyl threonine modification GO:0018210 3 0.012
regulation of steroid metabolic process GO:0019218 2 0.012
chromosome organization GO:0051276 360 0.012
negative regulation of cell cycle GO:0045786 116 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
hematopoietic or lymphoid organ development GO:0048534 57 0.012
positive regulation of neurogenesis GO:0050769 41 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
molting cycle GO:0042303 56 0.012
regulation of innate immune response GO:0045088 71 0.012
microtubule organizing center organization GO:0031023 168 0.012
wnt signaling pathway GO:0016055 98 0.012
salivary gland development GO:0007431 162 0.012
short term memory GO:0007614 19 0.012
positive regulation of protein catabolic process GO:0045732 34 0.012
protein targeting GO:0006605 64 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
regulation of cell shape GO:0008360 113 0.012
chemical homeostasis GO:0048878 92 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
eye photoreceptor cell development GO:0042462 81 0.012
protein targeting to nucleus GO:0044744 51 0.012
regulation of defense response to bacterium GO:1900424 30 0.012
sensory perception of sound GO:0007605 56 0.012
organic acid metabolic process GO:0006082 103 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
cellular protein catabolic process GO:0044257 83 0.012
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
convergent extension GO:0060026 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
tissue homeostasis GO:0001894 36 0.011
response to lipid GO:0033993 38 0.011
protein phosphorylation GO:0006468 169 0.011
actomyosin structure organization GO:0031032 56 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
positive regulation of molecular function GO:0044093 136 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.011
centrosome duplication GO:0051298 121 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of protein maturation GO:1903317 32 0.011
imaginal disc pattern formation GO:0007447 91 0.011
regulation of cell differentiation GO:0045595 302 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
germ cell migration GO:0008354 43 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
dna integrity checkpoint GO:0031570 81 0.011
regulation of synapse organization GO:0050807 110 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
response to nutrient GO:0007584 13 0.011
multi organism behavior GO:0051705 175 0.011
glycosyl compound metabolic process GO:1901657 127 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
multicellular organismal homeostasis GO:0048871 41 0.010
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.010
phosphorylation GO:0016310 294 0.010
negative regulation of catabolic process GO:0009895 36 0.010
segmentation GO:0035282 207 0.010
appendage morphogenesis GO:0035107 397 0.010
response to hexose GO:0009746 3 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
insulin receptor signaling pathway GO:0008286 25 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
outflow tract morphogenesis GO:0003151 4 0.010
cell motility GO:0048870 251 0.010

dl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.011
cardiovascular system disease DOID:1287 0 0.010
bone development disease DOID:0080006 0 0.010
bone disease DOID:0080001 0 0.010
connective tissue disease DOID:65 0 0.010