Drosophila melanogaster

111 known processes

MED11 (Dmel_CG6884)

Mediator complex subunit 11

(Aliases: Dmel\CG6884,CG6884,dMED21,Med21,Med11,anon-WO0153538.71,BcDNA:GH01072)

MED11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of neuroblast proliferation GO:0007406 27 0.998
negative regulation of stem cell proliferation GO:2000647 30 0.995
negative regulation of neural precursor cell proliferation GO:2000178 27 0.990
regulation of neuroblast proliferation GO:1902692 34 0.988
neuroblast proliferation GO:0007405 74 0.960
regulation of nervous system development GO:0051960 248 0.861
transcription from rna polymerase ii promoter GO:0006366 368 0.854
stem cell proliferation GO:0072089 88 0.840
regulation of stem cell proliferation GO:0072091 40 0.834
neural precursor cell proliferation GO:0061351 75 0.810
regulation of multicellular organismal development GO:2000026 414 0.775
cell proliferation GO:0008283 299 0.760
regulation of neural precursor cell proliferation GO:2000177 35 0.716
regulation of neurogenesis GO:0050767 158 0.622
negative regulation of cell differentiation GO:0045596 143 0.580
negative regulation of cell development GO:0010721 62 0.571
negative regulation of neurogenesis GO:0050768 53 0.554
regulation of cell differentiation GO:0045595 302 0.427
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.413
regulation of cell proliferation GO:0042127 163 0.381
cell cycle checkpoint GO:0000075 95 0.308
regulation of cell development GO:0060284 215 0.253
negative regulation of multicellular organismal process GO:0051241 142 0.252
regionalization GO:0003002 416 0.230
negative regulation of nervous system development GO:0051961 92 0.209
mitotic dna integrity checkpoint GO:0044774 75 0.207
regulation of gene expression epigenetic GO:0040029 128 0.166
dna templated transcription initiation GO:0006352 25 0.153
negative regulation of developmental process GO:0051093 201 0.123
exocrine system development GO:0035272 162 0.118
negative regulation of cell proliferation GO:0008285 69 0.113
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.106
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.101
mitotic g2 m transition checkpoint GO:0044818 70 0.094
positive regulation of rna metabolic process GO:0051254 271 0.089
embryo development ending in birth or egg hatching GO:0009792 152 0.086
negative regulation of rna metabolic process GO:0051253 251 0.085
rna processing GO:0006396 147 0.083
programmed cell death GO:0012501 257 0.082
organelle fission GO:0048285 340 0.081
muscle structure development GO:0061061 224 0.081
cell cell signaling involved in cell fate commitment GO:0045168 210 0.076
tissue morphogenesis GO:0048729 297 0.075
dna damage checkpoint GO:0000077 78 0.074
mitotic dna damage checkpoint GO:0044773 74 0.070
negative regulation of cellular biosynthetic process GO:0031327 277 0.070
pigmentation GO:0043473 75 0.070
morphogenesis of an epithelium GO:0002009 276 0.069
gland development GO:0048732 191 0.067
rna splicing via transesterification reactions GO:0000375 73 0.066
meiotic nuclear division GO:0007126 151 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.064
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.064
cellular response to dna damage stimulus GO:0006974 223 0.063
growth GO:0040007 359 0.058
regulation of intracellular signal transduction GO:1902531 236 0.057
gene silencing GO:0016458 138 0.057
cellular response to chemical stimulus GO:0070887 199 0.056
regulation of mrna splicing via spliceosome GO:0048024 64 0.055
apoptotic process GO:0006915 159 0.055
positive regulation of rna biosynthetic process GO:1902680 266 0.054
response to organic substance GO:0010033 284 0.054
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.054
salivary gland development GO:0007431 162 0.052
negative regulation of biosynthetic process GO:0009890 277 0.050
response to oxygen containing compound GO:1901700 200 0.050
organic substance catabolic process GO:1901575 308 0.048
small molecule metabolic process GO:0044281 305 0.048
anterior posterior pattern specification GO:0009952 136 0.045
regulation of meiosis GO:0040020 3 0.044
developmental programmed cell death GO:0010623 138 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
lateral inhibition GO:0046331 206 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
posttranscriptional gene silencing by rna GO:0035194 45 0.042
wnt signaling pathway GO:0016055 98 0.041
salivary gland morphogenesis GO:0007435 145 0.041
rna splicing GO:0008380 83 0.040
larval development GO:0002164 104 0.040
membrane organization GO:0061024 112 0.039
regulation of rna splicing GO:0043484 69 0.039
cellular response to organic substance GO:0071310 132 0.039
neuron maturation GO:0042551 31 0.038
positive regulation of transcription dna templated GO:0045893 266 0.038
covalent chromatin modification GO:0016569 106 0.038
gland morphogenesis GO:0022612 145 0.038
positive regulation of nucleic acid templated transcription GO:1903508 266 0.037
mrna processing GO:0006397 104 0.037
response to ketone GO:1901654 34 0.037
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
endocytosis GO:0006897 310 0.035
cell maturation GO:0048469 144 0.035
posttranscriptional gene silencing GO:0016441 46 0.032
embryonic axis specification GO:0000578 107 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.031
intracellular signal transduction GO:0035556 300 0.031
response to abiotic stimulus GO:0009628 341 0.030
vesicle mediated transport GO:0016192 381 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
regulation of response to stress GO:0080134 200 0.030
response to temperature stimulus GO:0009266 106 0.030
cellular amino acid metabolic process GO:0006520 61 0.029
immune effector process GO:0002252 98 0.029
tissue death GO:0016271 102 0.029
phagocytosis GO:0006909 215 0.029
rna localization GO:0006403 115 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
protein acylation GO:0043543 42 0.028
positive regulation of signaling GO:0023056 243 0.028
regulation of programmed cell death GO:0043067 152 0.028
regulation of mrna metabolic process GO:1903311 72 0.027
macromolecular complex assembly GO:0065003 256 0.027
rna interference GO:0016246 27 0.027
response to other organism GO:0051707 293 0.026
amide biosynthetic process GO:0043604 42 0.026
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.026
segmentation GO:0035282 207 0.025
negative regulation of rna biosynthetic process GO:1902679 240 0.025
regulation of immune system process GO:0002682 176 0.025
mrna splicing via spliceosome GO:0000398 73 0.025
negative regulation of gene expression GO:0010629 387 0.025
tripartite regional subdivision GO:0007351 103 0.025
embryonic pattern specification GO:0009880 174 0.024
axis specification GO:0009798 167 0.024
body morphogenesis GO:0010171 2 0.024
cellular response to oxygen containing compound GO:1901701 79 0.024
regulation of immune response GO:0050776 118 0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.023
cellular amide metabolic process GO:0043603 80 0.023
response to endogenous stimulus GO:0009719 119 0.023
cellular protein modification process GO:0006464 438 0.022
response to extracellular stimulus GO:0009991 116 0.022
developmental maturation GO:0021700 172 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
protein modification process GO:0036211 438 0.021
muscle organ development GO:0007517 127 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
negative regulation of cell cycle GO:0045786 116 0.021
response to organonitrogen compound GO:0010243 75 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
cellular macromolecular complex assembly GO:0034622 153 0.021
alternative mrna splicing via spliceosome GO:0000380 60 0.021
retina development in camera type eye GO:0060041 4 0.021
eye pigment biosynthetic process GO:0006726 32 0.020
regulation of gene silencing GO:0060968 63 0.020
regulation of growth GO:0040008 233 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
protein complex biogenesis GO:0070271 201 0.019
regulation of response to external stimulus GO:0032101 115 0.019
meiotic cell cycle GO:0051321 171 0.018
notch signaling pathway GO:0007219 120 0.018
aging GO:0007568 143 0.018
autophagic cell death GO:0048102 83 0.017
catabolic process GO:0009056 409 0.017
developmental growth GO:0048589 280 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
appendage development GO:0048736 401 0.017
appendage morphogenesis GO:0035107 397 0.017
positive regulation of developmental process GO:0051094 143 0.017
neuron remodeling GO:0016322 29 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
response to biotic stimulus GO:0009607 294 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
protein localization GO:0008104 284 0.016
mitotic cell cycle checkpoint GO:0007093 88 0.016
cellular catabolic process GO:0044248 372 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
spermatogenesis GO:0007283 200 0.016
response to bacterium GO:0009617 198 0.016
spindle organization GO:0007051 253 0.016
intracellular transport GO:0046907 228 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
regulation of apoptotic process GO:0042981 130 0.016
pigment metabolic process GO:0042440 84 0.015
regulation of cell cycle GO:0051726 291 0.015
positive regulation of multi organism process GO:0043902 40 0.015
chromosome organization GO:0051276 360 0.015
negative regulation of nucleotide catabolic process GO:0030812 1 0.015
response to alcohol GO:0097305 95 0.015
smoothened signaling pathway GO:0007224 49 0.014
axon development GO:0061564 297 0.014
single organism biosynthetic process GO:0044711 206 0.014
chromosome segregation GO:0007059 157 0.014
response to external biotic stimulus GO:0043207 293 0.014
protein dna complex subunit organization GO:0071824 86 0.014
molting cycle GO:0042303 56 0.014
stress activated mapk cascade GO:0051403 52 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
ncrna metabolic process GO:0034660 43 0.014
dna integrity checkpoint GO:0031570 81 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
defense response to bacterium GO:0042742 178 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
cell division GO:0051301 248 0.014
regulation of cell death GO:0010941 173 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
g2 dna damage checkpoint GO:0031572 69 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
gene silencing by rna GO:0031047 57 0.013
stem cell development GO:0048864 79 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
vesicle organization GO:0016050 44 0.013
peptidyl lysine acetylation GO:0018394 39 0.013
response to heat GO:0009408 63 0.013
endomembrane system organization GO:0010256 119 0.013
positive regulation of cellular amide metabolic process GO:0034250 26 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
regulation of mrna processing GO:0050684 71 0.012
salivary gland histolysis GO:0035070 88 0.012
phosphorylation GO:0016310 294 0.012
oocyte axis specification GO:0007309 108 0.012
positive regulation of defense response GO:0031349 59 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
regulation of developmental growth GO:0048638 174 0.012
blastoderm segmentation GO:0007350 159 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
rna transport GO:0050658 46 0.011
cell death GO:0008219 279 0.011
gonad development GO:0008406 50 0.011
histone lysine methylation GO:0034968 32 0.011
synaptic transmission GO:0007268 288 0.011
histone methylation GO:0016571 40 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
receptor mediated endocytosis GO:0006898 21 0.011
protein alkylation GO:0008213 43 0.011
negative regulation of cell communication GO:0010648 223 0.011
histolysis GO:0007559 102 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
positive regulation of response to biotic stimulus GO:0002833 31 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
secondary metabolic process GO:0019748 75 0.010
response to nitrogen compound GO:1901698 90 0.010
chromatin silencing GO:0006342 76 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
response to wounding GO:0009611 94 0.010
regulation of hydrolase activity GO:0051336 97 0.010
negative regulation of signaling GO:0023057 219 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
immune response GO:0006955 246 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
mitochondrial membrane organization GO:0007006 3 0.010

MED11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030