Drosophila melanogaster

25 known processes

Glu-RI (Dmel_CG8442)

Glutamate receptor I

(Aliases: CG8442,DGluRI,dglur-IA,Dmel\CG8442,DGluR-I,Glu-R1,dGluRI,DGluR-IA)

Glu-RI biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.180
sensory perception of salty taste GO:0050914 3 0.155
salt aversion GO:0035199 3 0.103
feeding behavior GO:0007631 50 0.096
ion transport GO:0006811 145 0.075
neurological system process GO:0050877 358 0.059
negative regulation of response to stimulus GO:0048585 258 0.058
g protein coupled receptor signaling pathway GO:0007186 136 0.058
negative regulation of cellular metabolic process GO:0031324 382 0.056
eye development GO:0001654 323 0.050
adult behavior GO:0030534 137 0.048
negative regulation of cellular biosynthetic process GO:0031327 277 0.048
homeostatic process GO:0042592 199 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.044
regulation of multicellular organismal development GO:2000026 414 0.044
locomotory behavior GO:0007626 176 0.044
growth GO:0040007 359 0.044
behavioral response to ethanol GO:0048149 49 0.043
axon development GO:0061564 297 0.042
response to organic substance GO:0010033 284 0.041
forebrain development GO:0030900 2 0.040
rhythmic process GO:0048511 106 0.040
negative regulation of biosynthetic process GO:0009890 277 0.039
positive regulation of gene expression GO:0010628 290 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
axonogenesis GO:0007409 290 0.038
eye morphogenesis GO:0048592 260 0.038
regulation of localization GO:0032879 275 0.037
camera type eye development GO:0043010 4 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
intracellular signal transduction GO:0035556 300 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.034
small molecule metabolic process GO:0044281 305 0.034
single organism biosynthetic process GO:0044711 206 0.034
response to abiotic stimulus GO:0009628 341 0.034
compound eye development GO:0048749 307 0.034
localization of cell GO:0051674 257 0.034
store operated calcium entry GO:0002115 3 0.033
vesicle mediated transport GO:0016192 381 0.033
establishment of localization in cell GO:0051649 402 0.033
regionalization GO:0003002 416 0.032
developmental growth GO:0048589 280 0.032
organic substance catabolic process GO:1901575 308 0.032
regulation of nervous system development GO:0051960 248 0.032
catabolic process GO:0009056 409 0.031
chemotaxis GO:0006935 249 0.031
cation transport GO:0006812 110 0.031
endocytosis GO:0006897 310 0.030
axon guidance GO:0007411 233 0.030
negative regulation of gene expression GO:0010629 387 0.029
organic substance transport GO:0071702 257 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
protein modification process GO:0036211 438 0.028
response to oxygen containing compound GO:1901700 200 0.028
sensory organ morphogenesis GO:0090596 260 0.028
single organism catabolic process GO:0044712 228 0.028
metal ion homeostasis GO:0055065 44 0.028
organophosphate metabolic process GO:0019637 195 0.028
neuron projection guidance GO:0097485 241 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
regulation of growth GO:0040008 233 0.027
regulation of neurogenesis GO:0050767 158 0.027
cell proliferation GO:0008283 299 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
detection of stimulus GO:0051606 156 0.027
protein localization GO:0008104 284 0.026
Fly
nucleotide metabolic process GO:0009117 161 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
cellular catabolic process GO:0044248 372 0.026
taxis GO:0042330 304 0.026
cell motility GO:0048870 251 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
sensory perception GO:0007600 196 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
phagocytosis GO:0006909 215 0.026
compound eye morphogenesis GO:0001745 249 0.026
tissue morphogenesis GO:0048729 297 0.025
neuron recognition GO:0008038 101 0.025
ion homeostasis GO:0050801 55 0.025
regulation of cell development GO:0060284 215 0.025
circadian rhythm GO:0007623 105 0.025
regulation of cell cycle GO:0051726 291 0.025
negative regulation of signal transduction GO:0009968 206 0.025
gland morphogenesis GO:0022612 145 0.025
kidney development GO:0001822 3 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
regulation of anatomical structure size GO:0090066 163 0.024
cell recognition GO:0008037 102 0.024
regulation of mitotic cell cycle GO:0007346 190 0.024
morphogenesis of an epithelium GO:0002009 276 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
telencephalon development GO:0021537 2 0.023
cellular protein modification process GO:0006464 438 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
tube morphogenesis GO:0035239 191 0.023
appendage development GO:0048736 401 0.023
negative regulation of cell communication GO:0010648 223 0.023
response to alcohol GO:0097305 95 0.023
regulation of catabolic process GO:0009894 170 0.022
positive regulation of signaling GO:0023056 243 0.022
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
open tracheal system development GO:0007424 204 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.022
phosphorylation GO:0016310 294 0.022
regulation of developmental growth GO:0048638 174 0.022
regulation of cell differentiation GO:0045595 302 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
cation homeostasis GO:0055080 51 0.022
regulation of intracellular signal transduction GO:1902531 236 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
regulation of cell cycle process GO:0010564 181 0.021
positive regulation of signal transduction GO:0009967 223 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
inorganic ion transmembrane transport GO:0098660 73 0.021
gtp catabolic process GO:0006184 72 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
negative regulation of rna metabolic process GO:0051253 251 0.021
organic acid metabolic process GO:0006082 103 0.021
single organism intracellular transport GO:1902582 207 0.021
negative regulation of transcription dna templated GO:0045892 237 0.020
appendage morphogenesis GO:0035107 397 0.020
transmembrane transport GO:0055085 139 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
cellular homeostasis GO:0019725 80 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
hindbrain development GO:0030902 2 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
wing disc morphogenesis GO:0007472 344 0.020
protein heterooligomerization GO:0051291 4 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
regulation of molecular function GO:0065009 217 0.020
oxoacid metabolic process GO:0043436 103 0.020
photoreceptor cell differentiation GO:0046530 170 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
negative regulation of signaling GO:0023057 219 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
nuclear division GO:0000280 332 0.019
organelle fission GO:0048285 340 0.019
body morphogenesis GO:0010171 2 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
salivary gland morphogenesis GO:0007435 145 0.019
regulation of transport GO:0051049 181 0.019
retina development in camera type eye GO:0060041 4 0.019
mitotic nuclear division GO:0007067 213 0.019
positive regulation of cell communication GO:0010647 250 0.019
Fly
ribonucleotide metabolic process GO:0009259 145 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
ras protein signal transduction GO:0007265 88 0.019
intracellular transport GO:0046907 228 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
actin cytoskeleton organization GO:0030036 206 0.019
metal ion transport GO:0030001 74 0.019
response to ethanol GO:0045471 59 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
connective tissue development GO:0061448 3 0.018
actin filament based process GO:0030029 220 0.018
divalent metal ion transport GO:0070838 26 0.018
protein transport GO:0015031 155 0.018
response to light stimulus GO:0009416 124 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
behavioral response to pain GO:0048266 3 0.018
nucleoside metabolic process GO:0009116 127 0.018
regulation of behavior GO:0050795 75 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.018
salivary gland development GO:0007431 162 0.018
anatomical structure homeostasis GO:0060249 97 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
heterocycle catabolic process GO:0046700 166 0.018
respiratory system development GO:0060541 213 0.018
secretion GO:0046903 109 0.018
synapse organization GO:0050808 196 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
regulation of response to stress GO:0080134 200 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
synaptic growth at neuromuscular junction GO:0051124 119 0.017
proteolysis GO:0006508 192 0.017
exocrine system development GO:0035272 162 0.017
nephron development GO:0072006 3 0.017
positive regulation of nucleotide metabolic process GO:0045981 55 0.017
epithelial cell differentiation GO:0030855 322 0.017
learning GO:0007612 75 0.017
establishment of protein localization GO:0045184 163 0.017
Fly
positive regulation of catabolic process GO:0009896 105 0.016
rhythmic behavior GO:0007622 76 0.016
cellular ion homeostasis GO:0006873 39 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
synapse assembly GO:0007416 143 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
positive regulation of developmental process GO:0051094 143 0.016
mating GO:0007618 120 0.016
neuromuscular synaptic transmission GO:0007274 67 0.016
Fly
eye photoreceptor cell differentiation GO:0001754 145 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
regulation of phosphorylation GO:0042325 147 0.016
divalent inorganic cation homeostasis GO:0072507 29 0.016
amine metabolic process GO:0009308 12 0.016
cellular lipid metabolic process GO:0044255 83 0.016
response to extracellular stimulus GO:0009991 116 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
adult locomotory behavior GO:0008344 76 0.016
aromatic compound catabolic process GO:0019439 166 0.016
regulation of catalytic activity GO:0050790 185 0.016
response to hexose GO:0009746 3 0.016
regulation of cellular localization GO:0060341 136 0.016
cellular amine metabolic process GO:0044106 12 0.016
death GO:0016265 284 0.016
camera type eye morphogenesis GO:0048593 2 0.015
locomotor rhythm GO:0045475 56 0.015
cation transmembrane transport GO:0098655 88 0.015
lipid metabolic process GO:0006629 121 0.015
response to nutrient levels GO:0031667 114 0.015
positive regulation of molecular function GO:0044093 136 0.015
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.015
regulation of cell proliferation GO:0042127 163 0.015
dendrite development GO:0016358 204 0.015
lateral inhibition GO:0046331 206 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
embryonic morphogenesis GO:0048598 206 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
tube development GO:0035295 244 0.015
cell death GO:0008219 279 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
neuropeptide signaling pathway GO:0007218 45 0.015
sensory perception of pain GO:0019233 4 0.015
polyol biosynthetic process GO:0046173 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
response to pain GO:0048265 3 0.015
regulation of cell death GO:0010941 173 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
epithelial cell development GO:0002064 274 0.015
response to monosaccharide GO:0034284 4 0.014
medium chain fatty acid metabolic process GO:0051791 1 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
multi organism behavior GO:0051705 175 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
cell migration GO:0016477 238 0.014
positive regulation of cell migration GO:0030335 2 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
cell division GO:0051301 248 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
detection of stimulus involved in sensory perception GO:0050906 92 0.014
head development GO:0060322 135 0.014
cellular macromolecule localization GO:0070727 220 0.014
protein complex biogenesis GO:0070271 201 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
organelle assembly GO:0070925 198 0.014
regulation of protein metabolic process GO:0051246 256 0.014
response to organophosphorus GO:0046683 2 0.014
purine containing compound catabolic process GO:0072523 112 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
associative learning GO:0008306 65 0.014
neural precursor cell proliferation GO:0061351 75 0.014
negative regulation of developmental process GO:0051093 201 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
purine containing compound metabolic process GO:0072521 155 0.014
notch signaling pathway GO:0007219 120 0.014
sensory perception of taste GO:0050909 25 0.014
nucleotide catabolic process GO:0009166 109 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
positive regulation of cell motility GO:2000147 3 0.014
positive regulation of gtp catabolic process GO:0033126 43 0.014
macromolecular complex assembly GO:0065003 256 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
nucleoside catabolic process GO:0009164 112 0.013
mapk cascade GO:0000165 107 0.013
response to hypoxia GO:0001666 53 0.013
chemical homeostasis GO:0048878 92 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
neuromuscular junction development GO:0007528 149 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
calcium ion homeostasis GO:0055074 23 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
gland development GO:0048732 191 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
brain development GO:0007420 120 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
biological adhesion GO:0022610 138 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
cellular response to carbohydrate stimulus GO:0071322 4 0.013
synaptic target recognition GO:0008039 45 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
spinal cord development GO:0021510 1 0.013
response to radiation GO:0009314 155 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
nitrogen compound transport GO:0071705 85 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
cell adhesion GO:0007155 136 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
endomembrane system organization GO:0010256 119 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
gtp metabolic process GO:0046039 72 0.013
organophosphate catabolic process GO:0046434 112 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
larval behavior GO:0030537 42 0.013
single organism cellular localization GO:1902580 180 0.013
detection of abiotic stimulus GO:0009582 66 0.013
ribose phosphate biosynthetic process GO:0046390 28 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
developmental maturation GO:0021700 172 0.012
secretion by cell GO:0032940 101 0.012
limb development GO:0060173 1 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
regulation of organelle organization GO:0033043 196 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
response to glucose GO:0009749 2 0.012
regulation of immune response GO:0050776 118 0.012
response to decreased oxygen levels GO:0036293 58 0.012
cell growth GO:0016049 108 0.012
programmed cell death GO:0012501 257 0.012
cell projection assembly GO:0030031 94 0.012
neuroblast proliferation GO:0007405 74 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
regulation of immune system process GO:0002682 176 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
circadian behavior GO:0048512 76 0.012
negative regulation of developmental growth GO:0048640 64 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
dendrite morphogenesis GO:0048813 199 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
immune response activating signal transduction GO:0002757 2 0.012
actin filament organization GO:0007015 126 0.012
central nervous system development GO:0007417 201 0.012
segmentation GO:0035282 207 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
sterol homeostasis GO:0055092 4 0.012
response to other organism GO:0051707 293 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
immune response GO:0006955 246 0.012
wnt signaling pathway GO:0016055 98 0.012
neuron fate commitment GO:0048663 50 0.012
positive regulation of transport GO:0051050 92 0.011
muscle organ development GO:0007517 127 0.011
positive regulation of nucleoside metabolic process GO:0045979 47 0.011
kidney morphogenesis GO:0060993 3 0.011
single organism membrane organization GO:0044802 93 0.011
response to oxygen levels GO:0070482 59 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
response to alkaloid GO:0043279 26 0.011
calcium ion transport GO:0006816 24 0.011
cell cycle phase transition GO:0044770 140 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
motor neuron axon guidance GO:0008045 58 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.011
regulation of programmed cell death GO:0043067 152 0.011
activation of innate immune response GO:0002218 4 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
cyclic nucleotide metabolic process GO:0009187 28 0.011
cellular amide metabolic process GO:0043603 80 0.011
cellular ketone metabolic process GO:0042180 24 0.011
negative regulation of growth GO:0045926 84 0.011
negative regulation of nervous system development GO:0051961 92 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
stem cell proliferation GO:0072089 88 0.011
photoreceptor cell development GO:0042461 96 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
cellular response to organic substance GO:0071310 132 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
ethanolamine containing compound metabolic process GO:0042439 4 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
sensory perception of chemical stimulus GO:0007606 116 0.011
protein complex assembly GO:0006461 200 0.011
purine containing compound biosynthetic process GO:0072522 30 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
regulation of proteolysis GO:0030162 87 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
cyclic purine nucleotide metabolic process GO:0052652 25 0.010
cellular metal ion homeostasis GO:0006875 31 0.010
cellular divalent inorganic cation homeostasis GO:0072503 23 0.010
anion homeostasis GO:0055081 3 0.010
regulation of response to external stimulus GO:0032101 115 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.010
ion transmembrane transport GO:0034220 122 0.010
rho protein signal transduction GO:0007266 14 0.010
intracellular protein transport GO:0006886 104 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
cell cell adhesion GO:0098609 26 0.010
ribonucleotide biosynthetic process GO:0009260 28 0.010
glycerolipid catabolic process GO:0046503 3 0.010
regulation of mapk cascade GO:0043408 92 0.010
chaeta development GO:0022416 97 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
response to organonitrogen compound GO:0010243 75 0.010
response to nitrogen compound GO:1901698 90 0.010
kidney epithelium development GO:0072073 3 0.010

Glu-RI disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.014
renal tubular transport disease DOID:447 0 0.012
kidney disease DOID:557 0 0.012
urinary system disease DOID:18 0 0.012
musculoskeletal system disease DOID:17 0 0.011
central nervous system disease DOID:331 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010