Drosophila melanogaster

14 known processes

Acon (Dmel_CG9244)

Aconitase

(Aliases: AconM,FBgn0010100,m-acon,CG9244,i59,i204,mAc,BEST:GH10550,Dmel\CG9244,M-Acon,ACON-1,l(2)07054,mAcon)

Acon biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
energy derivation by oxidation of organic compounds GO:0015980 32 0.962
cellular respiration GO:0045333 26 0.951
nad metabolic process GO:0019674 1 0.865
nicotinamide nucleotide metabolic process GO:0046496 2 0.806
nadh metabolic process GO:0006734 1 0.774
mitochondrion organization GO:0007005 65 0.640
oxidation reduction process GO:0055114 123 0.615
atp biosynthetic process GO:0006754 2 0.468
organic acid metabolic process GO:0006082 103 0.384
Rat
ribonucleoside biosynthetic process GO:0042455 3 0.336
ribonucleoside monophosphate metabolic process GO:0009161 51 0.329
tube morphogenesis GO:0035239 191 0.300
atp metabolic process GO:0046034 49 0.293
glycosyl compound metabolic process GO:1901657 127 0.252
nucleoside monophosphate metabolic process GO:0009123 52 0.242
tricarboxylic acid metabolic process GO:0072350 1 0.224
Rat
purine nucleoside monophosphate metabolic process GO:0009126 50 0.223
pyridine nucleotide metabolic process GO:0019362 2 0.223
establishment of localization in cell GO:0051649 402 0.217
ion transmembrane transport GO:0034220 122 0.216
nucleotide metabolic process GO:0009117 161 0.208
oxoacid metabolic process GO:0043436 103 0.206
Rat
single organism catabolic process GO:0044712 228 0.200
generation of precursor metabolites and energy GO:0006091 42 0.176
tube development GO:0035295 244 0.176
nucleoside phosphate metabolic process GO:0006753 162 0.175
carboxylic acid metabolic process GO:0019752 92 0.172
Rat
alpha amino acid metabolic process GO:1901605 20 0.172
organic substance catabolic process GO:1901575 308 0.167
nucleobase containing small molecule metabolic process GO:0055086 174 0.154
organonitrogen compound metabolic process GO:1901564 318 0.145
small molecule metabolic process GO:0044281 305 0.142
Rat
organophosphate metabolic process GO:0019637 195 0.140
defense response GO:0006952 300 0.136
purine ribonucleotide metabolic process GO:0009150 145 0.133
growth GO:0040007 359 0.128
cation transmembrane transport GO:0098655 88 0.107
camera type eye development GO:0043010 4 0.104
endocytosis GO:0006897 310 0.102
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.097
ion transport GO:0006811 145 0.097
oxidoreduction coenzyme metabolic process GO:0006733 2 0.096
purine ribonucleotide biosynthetic process GO:0009152 28 0.089
ribonucleoside metabolic process GO:0009119 127 0.088
immune system process GO:0002376 347 0.088
respiratory electron transport chain GO:0022904 11 0.087
regulation of multicellular organismal development GO:2000026 414 0.087
purine nucleoside biosynthetic process GO:0042451 3 0.084
negative regulation of neuroblast proliferation GO:0007406 27 0.084
ribonucleoside monophosphate catabolic process GO:0009158 39 0.079
intracellular transport GO:0046907 228 0.076
sperm mitochondrion organization GO:0030382 7 0.073
cellular catabolic process GO:0044248 372 0.073
ribose phosphate metabolic process GO:0019693 145 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.071
multi organism reproductive behavior GO:0044705 121 0.070
purine nucleoside metabolic process GO:0042278 127 0.070
transmembrane transport GO:0055085 139 0.068
small molecule catabolic process GO:0044282 21 0.068
single organism biosynthetic process GO:0044711 206 0.067
purine nucleotide metabolic process GO:0006163 146 0.067
vesicle mediated transport GO:0016192 381 0.066
developmental growth GO:0048589 280 0.066
purine nucleoside monophosphate catabolic process GO:0009128 38 0.066
cation transport GO:0006812 110 0.064
cellular protein complex assembly GO:0043623 71 0.062
purine ribonucleoside biosynthetic process GO:0046129 3 0.062
purine nucleoside triphosphate metabolic process GO:0009144 119 0.061
ribose phosphate biosynthetic process GO:0046390 28 0.061
eye development GO:0001654 323 0.060
ribonucleotide metabolic process GO:0009259 145 0.059
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.059
nucleoside triphosphate metabolic process GO:0009141 120 0.057
nucleoside metabolic process GO:0009116 127 0.056
striated muscle myosin thick filament assembly GO:0071688 3 0.056
negative regulation of stem cell proliferation GO:2000647 30 0.055
inorganic ion transmembrane transport GO:0098660 73 0.054
glycosyl compound biosynthetic process GO:1901659 3 0.054
regulation of organelle organization GO:0033043 196 0.054
pyridine containing compound metabolic process GO:0072524 3 0.050
digestive system development GO:0055123 149 0.050
purine nucleotide biosynthetic process GO:0006164 29 0.049
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.047
nucleoside monophosphate catabolic process GO:0009125 39 0.047
thioester metabolic process GO:0035383 3 0.046
kidney development GO:0001822 3 0.045
ribonucleotide catabolic process GO:0009261 109 0.044
cellular nitrogen compound catabolic process GO:0044270 165 0.043
multicellular organismal reproductive behavior GO:0033057 110 0.042
acyl coa metabolic process GO:0006637 3 0.042
response to other organism GO:0051707 293 0.042
response to external biotic stimulus GO:0043207 293 0.041
purine ribonucleoside metabolic process GO:0046128 127 0.039
purine containing compound biosynthetic process GO:0072522 30 0.039
citrate metabolic process GO:0006101 0 0.037
Rat
response to organic cyclic compound GO:0014070 89 0.037
centrosome organization GO:0051297 163 0.036
nucleoside biosynthetic process GO:0009163 3 0.036
macromolecular complex assembly GO:0065003 256 0.035
single organism intracellular transport GO:1902582 207 0.035
macromolecule catabolic process GO:0009057 161 0.034
cation homeostasis GO:0055080 51 0.034
ribonucleoside catabolic process GO:0042454 112 0.034
larval development GO:0002164 104 0.033
aerobic respiration GO:0009060 11 0.032
inorganic cation transmembrane transport GO:0098662 61 0.032
positive regulation of developmental process GO:0051094 143 0.031
aromatic compound catabolic process GO:0019439 166 0.031
response to oxygen containing compound GO:1901700 200 0.030
regulation of stem cell proliferation GO:0072091 40 0.030
atp catabolic process GO:0006200 38 0.030
programmed cell death GO:0012501 257 0.030
reproductive system development GO:0061458 74 0.029
purine containing compound catabolic process GO:0072523 112 0.029
regulation of cytoskeleton organization GO:0051493 89 0.029
purine containing compound metabolic process GO:0072521 155 0.029
acyl coa biosynthetic process GO:0071616 2 0.029
electron transport chain GO:0022900 14 0.028
phagocytosis GO:0006909 215 0.027
organic substance transport GO:0071702 257 0.027
organonitrogen compound catabolic process GO:1901565 128 0.027
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.027
embryonic morphogenesis GO:0048598 206 0.027
actin mediated cell contraction GO:0070252 21 0.027
regulation of molecular function GO:0065009 217 0.027
purine ribonucleoside catabolic process GO:0046130 112 0.026
retina development in camera type eye GO:0060041 4 0.025
intracellular signal transduction GO:0035556 300 0.025
renal system development GO:0072001 72 0.025
myofibril assembly GO:0030239 36 0.025
monovalent inorganic cation transport GO:0015672 40 0.024
oxidative phosphorylation GO:0006119 9 0.024
establishment of organelle localization GO:0051656 122 0.024
synaptic transmission GO:0007268 288 0.023
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
morphogenesis of a branching structure GO:0001763 45 0.022
mitochondrial fusion GO:0008053 7 0.022
reproductive structure development GO:0048608 74 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
response to bacterium GO:0009617 198 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
organonitrogen compound biosynthetic process GO:1901566 117 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
protein modification by small protein removal GO:0070646 28 0.020
heterocycle catabolic process GO:0046700 166 0.020
metal ion transport GO:0030001 74 0.020
urogenital system development GO:0001655 72 0.019
neurological system process GO:0050877 358 0.019
neuroblast proliferation GO:0007405 74 0.019
purine ribonucleotide catabolic process GO:0009154 109 0.019
regulation of cell development GO:0060284 215 0.019
multi multicellular organism process GO:0044706 123 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
chaeta development GO:0022416 97 0.018
nucleoside triphosphate biosynthetic process GO:0009142 2 0.018
regulation of catabolic process GO:0009894 170 0.018
protein complex biogenesis GO:0070271 201 0.018
multi organism behavior GO:0051705 175 0.018
death GO:0016265 284 0.018
carbohydrate metabolic process GO:0005975 82 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.018
nucleoside monophosphate biosynthetic process GO:0009124 4 0.018
purine nucleoside catabolic process GO:0006152 112 0.017
organic anion transport GO:0015711 28 0.017
catabolic process GO:0009056 409 0.017
regulation of transport GO:0051049 181 0.017
protein complex assembly GO:0006461 200 0.016
multicellular organismal aging GO:0010259 140 0.016
central nervous system development GO:0007417 201 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
homeostatic process GO:0042592 199 0.016
reactive oxygen species metabolic process GO:0072593 22 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
thioester biosynthetic process GO:0035384 2 0.015
phagocytosis engulfment GO:0006911 11 0.015
response to organic substance GO:0010033 284 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
digestive tract development GO:0048565 149 0.015
regulation of membrane potential GO:0042391 35 0.015
apoptotic process GO:0006915 159 0.015
skeletal muscle fiber development GO:0048741 3 0.015
cellular response to organic cyclic compound GO:0071407 32 0.015
organelle localization GO:0051640 148 0.014
neural precursor cell proliferation GO:0061351 75 0.014
positive regulation of molecular function GO:0044093 136 0.014
mitochondrial atp synthesis coupled electron transport GO:0042775 8 0.014
proton transport GO:0015992 7 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
proteolysis GO:0006508 192 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
very long chain fatty acid catabolic process GO:0042760 2 0.013
atp synthesis coupled electron transport GO:0042773 8 0.013
cellular response to organic substance GO:0071310 132 0.012
anion transport GO:0006820 41 0.012
regulation of cell cycle GO:0051726 291 0.012
negative regulation of nervous system development GO:0051961 92 0.012
sex differentiation GO:0007548 81 0.012
sensory organ morphogenesis GO:0090596 260 0.012
response to metal ion GO:0010038 23 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
mitotic cytokinesis GO:0000281 50 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
biological adhesion GO:0022610 138 0.011
negative regulation of cell development GO:0010721 62 0.011
gonad development GO:0008406 50 0.011
response to wounding GO:0009611 94 0.011
determination of adult lifespan GO:0008340 137 0.011
protein targeting GO:0006605 64 0.011
response to monosaccharide GO:0034284 4 0.011
oviposition GO:0018991 19 0.011
cell death GO:0008219 279 0.011
regionalization GO:0003002 416 0.010
regulation of neurogenesis GO:0050767 158 0.010
response to hexose GO:0009746 3 0.010
chemical homeostasis GO:0048878 92 0.010
response to organonitrogen compound GO:0010243 75 0.010

Acon disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
musculoskeletal system disease DOID:17 0 0.023
nervous system disease DOID:863 0 0.012