Drosophila melanogaster

79 known processes

btz (Dmel_CG12878)

barentsz

(Aliases: Dmel\CG12878,CG12878,wkl,Btz)

btz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell development GO:0030707 248 0.895
epithelial cell differentiation GO:0030855 322 0.621
cell migration GO:0016477 238 0.594
regionalization GO:0003002 416 0.568
establishment or maintenance of cell polarity GO:0007163 167 0.556
cellular response to chemical stimulus GO:0070887 199 0.552
cellular protein complex disassembly GO:0043624 35 0.532
embryo development ending in birth or egg hatching GO:0009792 152 0.510
organelle assembly GO:0070925 198 0.455
epithelial cell development GO:0002064 274 0.409
axis specification GO:0009798 167 0.395
oocyte development GO:0048599 124 0.395
cell motility GO:0048870 251 0.382
negative regulation of signal transduction GO:0009968 206 0.350
columnar cuboidal epithelial cell development GO:0002066 249 0.348
cellular component assembly involved in morphogenesis GO:0010927 151 0.336
negative regulation of cellular biosynthetic process GO:0031327 277 0.324
cellular response to organic substance GO:0071310 132 0.317
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.312
axonogenesis GO:0007409 290 0.310
localization of cell GO:0051674 257 0.304
organelle localization GO:0051640 148 0.303
organelle fission GO:0048285 340 0.303
segmentation GO:0035282 207 0.299
establishment of localization in cell GO:0051649 402 0.280
single organism intracellular transport GO:1902582 207 0.277
cellular protein modification process GO:0006464 438 0.274
eggshell formation GO:0030703 105 0.253
negative regulation of gene expression GO:0010629 387 0.247
germ cell migration GO:0008354 43 0.246
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.243
negative regulation of cell communication GO:0010648 223 0.238
oocyte differentiation GO:0009994 145 0.219
response to organic substance GO:0010033 284 0.213
single organism cellular localization GO:1902580 180 0.206
negative regulation of biosynthetic process GO:0009890 277 0.203
anterior posterior axis specification embryo GO:0008595 103 0.201
positive regulation of macromolecule metabolic process GO:0010604 405 0.201
cytokinesis GO:0000910 90 0.200
cellular response to endogenous stimulus GO:0071495 80 0.192
protein modification by small protein conjugation or removal GO:0070647 106 0.180
tissue migration GO:0090130 155 0.176
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.175
intracellular transport GO:0046907 228 0.172
wnt signaling pathway GO:0016055 98 0.168
negative regulation of rna metabolic process GO:0051253 251 0.159
negative regulation of signaling GO:0023057 219 0.158
negative regulation of response to stimulus GO:0048585 258 0.153
developmental growth GO:0048589 280 0.151
response to endogenous stimulus GO:0009719 119 0.150
establishment of planar polarity GO:0001736 87 0.150
regulation of organelle organization GO:0033043 196 0.143
tripartite regional subdivision GO:0007351 103 0.137
mapk cascade GO:0000165 107 0.136
transcription from rna polymerase ii promoter GO:0006366 368 0.135
growth GO:0040007 359 0.134
immune system process GO:0002376 347 0.132
anterior posterior axis specification GO:0009948 109 0.130
chemotaxis GO:0006935 249 0.129
nuclear division GO:0000280 332 0.129
cellular macromolecule localization GO:0070727 220 0.123
imaginal disc derived wing morphogenesis GO:0007476 337 0.121
rna localization GO:0006403 115 0.117
gonad development GO:0008406 50 0.114
cellular protein localization GO:0034613 160 0.110
response to external biotic stimulus GO:0043207 293 0.108
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.107
protein modification process GO:0036211 438 0.106
actin cytoskeleton organization GO:0030036 206 0.106
intracellular protein transport GO:0006886 104 0.104
defense response to bacterium GO:0042742 178 0.103
epithelial cell migration GO:0010631 148 0.103
regulation of phosphate metabolic process GO:0019220 210 0.101
eggshell chorion assembly GO:0007306 66 0.099
regulation of molecular function GO:0065009 217 0.098
positive regulation of response to stimulus GO:0048584 323 0.098
negative regulation of protein depolymerization GO:1901880 23 0.093
regulation of multicellular organismal development GO:2000026 414 0.092
response to bacterium GO:0009617 198 0.092
phosphorylation GO:0016310 294 0.091
organic substance transport GO:0071702 257 0.091
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.089
regulation of protein metabolic process GO:0051246 256 0.088
embryonic axis specification GO:0000578 107 0.084
regulation of intracellular signal transduction GO:1902531 236 0.084
response to abiotic stimulus GO:0009628 341 0.084
regulation of cell cycle process GO:0010564 181 0.084
cellular catabolic process GO:0044248 372 0.082
rna splicing via transesterification reactions GO:0000375 73 0.080
developmental maturation GO:0021700 172 0.080
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.080
response to other organism GO:0051707 293 0.079
cell division GO:0051301 248 0.079
negative regulation of cellular metabolic process GO:0031324 382 0.078
blastoderm segmentation GO:0007350 159 0.077
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.077
reproductive structure development GO:0048608 74 0.076
regulation of microtubule cytoskeleton organization GO:0070507 41 0.076
mitotic nuclear division GO:0007067 213 0.075
tissue morphogenesis GO:0048729 297 0.075
signal transduction by phosphorylation GO:0023014 107 0.073
positive regulation of cellular biosynthetic process GO:0031328 316 0.072
positive regulation of gene expression GO:0010628 290 0.071
intracellular signal transduction GO:0035556 300 0.070
mitotic spindle organization GO:0007052 220 0.068
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.068
oocyte axis specification GO:0007309 108 0.068
cuticle development GO:0042335 86 0.067
axon guidance GO:0007411 233 0.067
morphogenesis of a polarized epithelium GO:0001738 93 0.066
defense response to other organism GO:0098542 225 0.065
wing disc morphogenesis GO:0007472 344 0.065
negative regulation of rna biosynthetic process GO:1902679 240 0.064
protein phosphorylation GO:0006468 169 0.062
positive regulation of phosphate metabolic process GO:0045937 139 0.061
posttranscriptional regulation of gene expression GO:0010608 145 0.061
spindle organization GO:0007051 253 0.061
cytoplasmic transport GO:0016482 130 0.060
positive regulation of rna metabolic process GO:0051254 271 0.059
ribonucleoprotein complex subunit organization GO:0071826 28 0.058
epithelium migration GO:0090132 148 0.057
protein targeting GO:0006605 64 0.057
post embryonic appendage morphogenesis GO:0035120 385 0.057
protein localization to organelle GO:0033365 82 0.057
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.056
positive regulation of biosynthetic process GO:0009891 316 0.056
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.056
posttranscriptional gene silencing GO:0016441 46 0.055
regulation of cell cycle GO:0051726 291 0.055
establishment of tissue polarity GO:0007164 87 0.054
oocyte construction GO:0007308 112 0.054
reproductive system development GO:0061458 74 0.054
cellular response to oxygen containing compound GO:1901701 79 0.054
cell cell signaling involved in cell fate commitment GO:0045168 210 0.053
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.052
antimicrobial humoral response GO:0019730 99 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.050
asymmetric cell division GO:0008356 37 0.050
pole plasm rna localization GO:0007316 52 0.050
body morphogenesis GO:0010171 2 0.050
macromolecular complex assembly GO:0065003 256 0.048
molting cycle GO:0042303 56 0.048
regulation of phosphorus metabolic process GO:0051174 210 0.047
protein complex assembly GO:0006461 200 0.047
establishment of organelle localization GO:0051656 122 0.046
establishment of cell polarity GO:0030010 40 0.046
positive regulation of cell communication GO:0010647 250 0.046
regulation of cell differentiation GO:0045595 302 0.045
stem cell differentiation GO:0048863 117 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.044
anterior posterior pattern specification GO:0009952 136 0.044
nuclear transport GO:0051169 72 0.044
regulation of localization GO:0032879 275 0.043
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.043
axon development GO:0061564 297 0.043
guanosine containing compound metabolic process GO:1901068 74 0.042
maternal determination of anterior posterior axis embryo GO:0008358 74 0.042
negative regulation of translation GO:0017148 28 0.041
gland development GO:0048732 191 0.041
nucleus localization GO:0051647 34 0.041
ameboidal type cell migration GO:0001667 151 0.041
taxis GO:0042330 304 0.041
brain development GO:0007420 120 0.040
death GO:0016265 284 0.040
cellular macromolecular complex assembly GO:0034622 153 0.039
cytoplasm organization GO:0007028 64 0.039
regulation of wnt signaling pathway GO:0030111 68 0.038
organic substance catabolic process GO:1901575 308 0.038
appendage morphogenesis GO:0035107 397 0.038
positive regulation of signal transduction GO:0009967 223 0.038
programmed cell death GO:0012501 257 0.037
non sensory hair organization GO:0035316 47 0.037
cell death GO:0008219 279 0.037
dorsal ventral axis specification GO:0009950 66 0.036
negative regulation of developmental process GO:0051093 201 0.036
immune response GO:0006955 246 0.035
morphogenesis of an epithelium GO:0002009 276 0.034
response to radiation GO:0009314 155 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.033
protein complex biogenesis GO:0070271 201 0.033
response to alcohol GO:0097305 95 0.033
nucleocytoplasmic transport GO:0006913 72 0.033
regulation of embryonic development GO:0045995 68 0.032
positive regulation of nucleic acid templated transcription GO:1903508 266 0.032
sex differentiation GO:0007548 81 0.032
oocyte dorsal ventral axis specification GO:0007310 34 0.032
larval development GO:0002164 104 0.032
regulation of immune system process GO:0002682 176 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.032
gene silencing by rna GO:0031047 57 0.032
protein localization GO:0008104 284 0.031
negative regulation of cytoskeleton organization GO:0051494 30 0.031
gtp metabolic process GO:0046039 72 0.031
macromolecular complex disassembly GO:0032984 37 0.031
cell maturation GO:0048469 144 0.030
connective tissue development GO:0061448 3 0.030
gland morphogenesis GO:0022612 145 0.030
cell projection assembly GO:0030031 94 0.030
vesicle mediated transport GO:0016192 381 0.030
ras protein signal transduction GO:0007265 88 0.029
mrna splicing via spliceosome GO:0000398 73 0.029
dendrite morphogenesis GO:0048813 199 0.029
regulation of purine nucleotide catabolic process GO:0033121 48 0.029
regulation of transport GO:0051049 181 0.028
response to oxygen containing compound GO:1901700 200 0.028
catabolic process GO:0009056 409 0.028
embryonic pattern specification GO:0009880 174 0.028
regulation of intracellular transport GO:0032386 64 0.028
cellularization GO:0007349 90 0.028
regulation of nucleotide metabolic process GO:0006140 62 0.028
regulation of ras gtpase activity GO:0032318 38 0.027
mrna processing GO:0006397 104 0.027
regulation of chromosome organization GO:0033044 64 0.027
negative regulation of wnt signaling pathway GO:0030178 28 0.027
positive regulation of signaling GO:0023056 243 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.026
posttranscriptional gene silencing by rna GO:0035194 45 0.026
centrosome organization GO:0051297 163 0.026
positive regulation of transcription dna templated GO:0045893 266 0.025
regulation of mrna splicing via spliceosome GO:0048024 64 0.025
cell fate determination GO:0001709 91 0.025
head development GO:0060322 135 0.024
biological adhesion GO:0022610 138 0.024
developmental growth involved in morphogenesis GO:0060560 65 0.024
protein import GO:0017038 55 0.024
male gamete generation GO:0048232 201 0.024
defense response GO:0006952 300 0.024
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
positive regulation of ras gtpase activity GO:0032320 36 0.023
negative regulation of cell differentiation GO:0045596 143 0.023
multi organism behavior GO:0051705 175 0.023
protein ubiquitination GO:0016567 70 0.023
positive regulation of protein metabolic process GO:0051247 128 0.022
regulation of protein phosphorylation GO:0001932 64 0.022
response to biotic stimulus GO:0009607 294 0.022
cellular component disassembly GO:0022411 46 0.022
regulation of dna metabolic process GO:0051052 34 0.022
appendage development GO:0048736 401 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
regulation of mapk cascade GO:0043408 92 0.022
response to nitrogen compound GO:1901698 90 0.022
protein depolymerization GO:0051261 31 0.022
single organismal cell cell adhesion GO:0016337 45 0.021
nucleobase containing compound transport GO:0015931 56 0.021
pole plasm oskar mrna localization GO:0045451 46 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
regulation of cell adhesion GO:0030155 27 0.021
cytoskeleton dependent cytokinesis GO:0061640 81 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
anatomical structure homeostasis GO:0060249 97 0.021
meiotic cell cycle GO:0051321 171 0.021
regulation of phosphorylation GO:0042325 147 0.021
oocyte microtubule cytoskeleton organization GO:0016325 35 0.021
protein complex disassembly GO:0043241 36 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
cellular response to nitrogen compound GO:1901699 51 0.021
developmental programmed cell death GO:0010623 138 0.020
regulation of anatomical structure size GO:0090066 163 0.020
salivary gland development GO:0007431 162 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
regulation of protein depolymerization GO:1901879 27 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.020
establishment of spindle localization GO:0051293 22 0.020
regulation of actin polymerization or depolymerization GO:0008064 27 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
mrna metabolic process GO:0016071 124 0.020
dorsal appendage formation GO:0046843 47 0.020
pole plasm assembly GO:0007315 61 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
histolysis GO:0007559 102 0.019
regulation of catalytic activity GO:0050790 185 0.019
necrotic cell death GO:0070265 1 0.019
cilium morphogenesis GO:0060271 39 0.019
asymmetric protein localization GO:0008105 33 0.019
chorion containing eggshell formation GO:0007304 105 0.019
genitalia development GO:0048806 26 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
muscle cell development GO:0055001 50 0.018
salivary gland morphogenesis GO:0007435 145 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
cellular response to growth factor stimulus GO:0071363 30 0.018
pole cell development GO:0007277 26 0.018
regulation of protein localization GO:0032880 76 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
positive regulation of nucleotide catabolic process GO:0030813 46 0.018
humoral immune response GO:0006959 117 0.018
imaginal disc derived wing hair organization GO:0035317 45 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.018
response to growth factor GO:0070848 31 0.018
striated muscle cell differentiation GO:0051146 90 0.017
immune effector process GO:0002252 98 0.017
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
transmembrane transport GO:0055085 139 0.017
camera type eye morphogenesis GO:0048593 2 0.017
positive regulation of phosphorylation GO:0042327 87 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
cellular response to organic cyclic compound GO:0071407 32 0.017
oocyte anterior posterior axis specification GO:0007314 72 0.017
aging GO:0007568 143 0.017
central nervous system development GO:0007417 201 0.017
cell adhesion GO:0007155 136 0.017
negative regulation of protein metabolic process GO:0051248 85 0.016
positive regulation of mapk cascade GO:0043410 63 0.016
development of primary sexual characteristics GO:0045137 50 0.016
respiratory system development GO:0060541 213 0.016
phagocytosis GO:0006909 215 0.016
instar larval development GO:0002168 55 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
innate immune response GO:0045087 144 0.016
regulation of rna splicing GO:0043484 69 0.016
organophosphate metabolic process GO:0019637 195 0.016
macromolecule catabolic process GO:0009057 161 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
axis elongation GO:0003401 3 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
spermatogenesis GO:0007283 200 0.015
border follicle cell migration GO:0007298 113 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
response to heat GO:0009408 63 0.015
regulation of catabolic process GO:0009894 170 0.015
cell proliferation GO:0008283 299 0.015
gtp catabolic process GO:0006184 72 0.015
intracellular mrna localization GO:0008298 66 0.015
protein transport GO:0015031 155 0.015
cellular protein complex assembly GO:0043623 71 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
regulation of translation GO:0006417 56 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.014
histone methylation GO:0016571 40 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
microtubule based movement GO:0007018 51 0.014
positive regulation of gtpase activity GO:0043547 43 0.014
positive regulation of nucleoside metabolic process GO:0045979 47 0.014
response to ketone GO:1901654 34 0.014
regulation of protein complex disassembly GO:0043244 29 0.014
regulation of microtubule depolymerization GO:0031114 24 0.014
alternative mrna splicing via spliceosome GO:0000380 60 0.014
negative regulation of protein complex disassembly GO:0043242 23 0.014
ovarian follicle cell migration GO:0007297 121 0.014
ribonucleoprotein complex biogenesis GO:0022613 31 0.013
regulation of phosphatase activity GO:0010921 3 0.013
response to ecdysone GO:0035075 34 0.013
single organism catabolic process GO:0044712 228 0.013
autophagy GO:0006914 108 0.013
germ line stem cell division GO:0042078 25 0.013
chaeta development GO:0022416 97 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
ribonucleoprotein complex assembly GO:0022618 23 0.013
microtubule organizing center organization GO:0031023 168 0.013
salivary gland histolysis GO:0035070 88 0.013
positive regulation of gtp catabolic process GO:0033126 43 0.013
single organism cell adhesion GO:0098602 47 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
neuron projection guidance GO:0097485 241 0.013
regulation of dna templated transcription elongation GO:0032784 17 0.013
stem cell maintenance GO:0019827 67 0.013
determination of adult lifespan GO:0008340 137 0.013
regulation of gtp catabolic process GO:0033124 44 0.013
regulation of developmental growth GO:0048638 174 0.012
stem cell development GO:0048864 79 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
positive regulation of wnt signaling pathway GO:0030177 25 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
lateral inhibition GO:0046331 206 0.012
mitochondrial transport GO:0006839 8 0.012
apoptotic process GO:0006915 159 0.012
chitin based cuticle development GO:0040003 49 0.012
exocrine system development GO:0035272 162 0.012
single organism membrane organization GO:0044802 93 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
carbohydrate metabolic process GO:0005975 82 0.012
gene silencing GO:0016458 138 0.012
methylation GO:0032259 47 0.012
regulation of canonical wnt signaling pathway GO:0060828 15 0.012
regulation of cellular localization GO:0060341 136 0.012
regulation of protein modification process GO:0031399 112 0.012
negative regulation of microtubule depolymerization GO:0007026 21 0.012
digestive tract development GO:0048565 149 0.012
positive regulation of molecular function GO:0044093 136 0.011
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.011
regulation of hydrolase activity GO:0051336 97 0.011
purine containing compound metabolic process GO:0072521 155 0.011
response to lipid GO:0033993 38 0.011
negative regulation of organelle organization GO:0010639 56 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
single organism behavior GO:0044708 391 0.011
regulation of cell development GO:0060284 215 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
response to organonitrogen compound GO:0010243 75 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
protein import into nucleus GO:0006606 51 0.011
compound eye development GO:0048749 307 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
cellular response to organonitrogen compound GO:0071417 36 0.011
heterocycle catabolic process GO:0046700 166 0.011
microtubule based transport GO:0010970 42 0.011
regulation of insulin receptor signaling pathway GO:0046626 17 0.010
cytoskeleton dependent intracellular transport GO:0030705 44 0.010
protein localization to nucleus GO:0034504 55 0.010
cell growth GO:0016049 108 0.010
cellular response to lipid GO:0071396 20 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
regulation of cell projection organization GO:0031344 92 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
actin filament based process GO:0030029 220 0.010
positive regulation of developmental process GO:0051094 143 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
hemopoiesis GO:0030097 46 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010

btz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018