Drosophila melanogaster

245 known processes

aop (Dmel_CG3166)

anterior open

(Aliases: DROYANETSB,Yan/Aop,yan,Aop/Yan,AOP,Yan,YAN,yan/pok,pok,Aop,CG3166,Dmel\CG3166,DROYANET,aop/yan,SK2-1)

aop biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial cell migration GO:0010631 148 1.000
epithelial cell differentiation GO:0030855 322 1.000
border follicle cell migration GO:0007298 113 0.999
columnar cuboidal epithelial cell development GO:0002066 249 0.999
cell motility GO:0048870 251 0.997
cell migration GO:0016477 238 0.997
ovarian follicle cell development GO:0030707 248 0.997
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.997
ameboidal type cell migration GO:0001667 151 0.994
tissue migration GO:0090130 155 0.991
establishment of ommatidial planar polarity GO:0042067 49 0.990
hemocyte differentiation GO:0042386 38 0.985
localization of cell GO:0051674 257 0.985
axonogenesis GO:0007409 290 0.983
stem cell fate commitment GO:0048865 25 0.982
ovarian follicle cell migration GO:0007297 121 0.976
spermatid differentiation GO:0048515 114 0.975
taxis GO:0042330 304 0.972
axon development GO:0061564 297 0.971
spermatid development GO:0007286 98 0.967
neuron projection guidance GO:0097485 241 0.964
muscle cell differentiation GO:0042692 103 0.955
establishment of planar polarity GO:0001736 87 0.944
respiratory system development GO:0060541 213 0.942
epithelium migration GO:0090132 148 0.941
regulation of nervous system development GO:0051960 248 0.939
positive regulation of macromolecule metabolic process GO:0010604 405 0.937
Mouse Fly
cellular response to external stimulus GO:0071496 66 0.937
epithelial cell development GO:0002064 274 0.931
regulation of neurogenesis GO:0050767 158 0.929
immune system process GO:0002376 347 0.928
r3 r4 cell fate commitment GO:0007464 10 0.916
urogenital system development GO:0001655 72 0.914
meiotic cell cycle GO:0051321 171 0.911
negative regulation of rna biosynthetic process GO:1902679 240 0.908
regulation of organ morphogenesis GO:2000027 78 0.901
outflow tract morphogenesis GO:0003151 4 0.900
regulation of immune system process GO:0002682 176 0.898
morphogenesis of an epithelium GO:0002009 276 0.896
embryonic morphogenesis GO:0048598 206 0.892
peripheral nervous system development GO:0007422 52 0.886
regulation of intracellular signal transduction GO:1902531 236 0.885
regulation of cell development GO:0060284 215 0.884
positive regulation of neurogenesis GO:0050769 41 0.878
autophagy GO:0006914 108 0.872
Fly
embryonic heart tube development GO:0035050 22 0.869
regulation of axonogenesis GO:0050770 32 0.866
open tracheal system development GO:0007424 204 0.861
male gamete generation GO:0048232 201 0.861
cellular protein modification process GO:0006464 438 0.856
negative regulation of cell cycle GO:0045786 116 0.855
positive regulation of gene expression GO:0010628 290 0.853
Mouse Fly
renal tubule development GO:0061326 64 0.851
positive regulation of transcription dna templated GO:0045893 266 0.848
Mouse Fly
negative regulation of rna metabolic process GO:0051253 251 0.840
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.840
Mouse Fly
glial cell migration GO:0008347 31 0.834
protein localization to nucleus GO:0034504 55 0.832
negative regulation of response to stimulus GO:0048585 258 0.829
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.827
trachea morphogenesis GO:0060439 22 0.815
regionalization GO:0003002 416 0.802
intracellular transport GO:0046907 228 0.798
establishment of tissue polarity GO:0007164 87 0.797
tissue morphogenesis GO:0048729 297 0.789
response to abiotic stimulus GO:0009628 341 0.788
regulation of anatomical structure morphogenesis GO:0022603 242 0.780
cell projection assembly GO:0030031 94 0.778
epithelial tube morphogenesis GO:0060562 88 0.776
intracellular signal transduction GO:0035556 300 0.771
regulation of epithelial cell migration GO:0010632 12 0.760
spermatogenesis GO:0007283 200 0.759
nephron development GO:0072006 3 0.758
establishment or maintenance of cell polarity GO:0007163 167 0.757
immune effector process GO:0002252 98 0.754
protein modification process GO:0036211 438 0.751
neuroblast fate commitment GO:0014017 19 0.748
r3 r4 cell differentiation GO:0048056 12 0.747
phosphorylation GO:0016310 294 0.739
eggshell formation GO:0030703 105 0.730
myoblast fusion GO:0007520 43 0.720
compound eye photoreceptor fate commitment GO:0001752 36 0.719
enzyme linked receptor protein signaling pathway GO:0007167 179 0.718
syncytium formation by plasma membrane fusion GO:0000768 43 0.714
regulation of multicellular organismal development GO:2000026 414 0.711
maintenance of protein location GO:0045185 28 0.707
dorsal appendage formation GO:0046843 47 0.706
tube development GO:0035295 244 0.702
protein import into nucleus GO:0006606 51 0.700
embryonic pattern specification GO:0009880 174 0.698
kidney epithelium development GO:0072073 3 0.697
regulation of hemocyte differentiation GO:0045610 22 0.688
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.687
dorsal closure amnioserosa morphology change GO:0046664 7 0.679
mapk cascade GO:0000165 107 0.673
meiotic nuclear division GO:0007126 151 0.672
immune response GO:0006955 246 0.671
embryonic hemopoiesis GO:0035162 26 0.670
renal system development GO:0072001 72 0.664
positive regulation of cell differentiation GO:0045597 64 0.656
skin development GO:0043588 65 0.652
axon guidance GO:0007411 233 0.641
positive regulation of rna metabolic process GO:0051254 271 0.639
Mouse Fly
cell proliferation GO:0008283 299 0.635
protein transport GO:0015031 155 0.635
regulation of r7 cell differentiation GO:0045676 15 0.631
regulation of cell morphogenesis GO:0022604 163 0.628
eggshell chorion assembly GO:0007306 66 0.619
organ formation GO:0048645 39 0.614
wnt signaling pathway GO:0016055 98 0.614
protein localization GO:0008104 284 0.610
regulation of actin filament based process GO:0032970 42 0.609
salivary gland development GO:0007431 162 0.609
Fly
regulation of cytoskeleton organization GO:0051493 89 0.605
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.593
blastoderm segmentation GO:0007350 159 0.591
muscle structure development GO:0061061 224 0.588
chorion containing eggshell formation GO:0007304 105 0.580
apoptotic signaling pathway GO:0097190 27 0.577
regulation of photoreceptor cell differentiation GO:0046532 34 0.575
defense response to other organism GO:0098542 225 0.572
morphogenesis of a branching structure GO:0001763 45 0.570
single organism nuclear import GO:1902593 51 0.568
exocrine system development GO:0035272 162 0.562
Fly
photoreceptor cell fate commitment GO:0046552 41 0.561
eye antennal disc morphogenesis GO:0007455 34 0.556
cellular macromolecule localization GO:0070727 220 0.555
glial cell fate determination GO:0007403 3 0.553
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.548
protein localization to organelle GO:0033365 82 0.548
neurological system process GO:0050877 358 0.539
r7 cell differentiation GO:0045466 43 0.538
morphogenesis of a polarized epithelium GO:0001738 93 0.535
fusion cell fate specification GO:0035156 4 0.534
negative regulation of nucleic acid templated transcription GO:1903507 240 0.533
ras protein signal transduction GO:0007265 88 0.532
sensory organ morphogenesis GO:0090596 260 0.526
protein targeting GO:0006605 64 0.524
malpighian tubule development GO:0072002 64 0.515
nuclear import GO:0051170 51 0.511
germarium derived egg chamber formation GO:0007293 101 0.502
cellular protein localization GO:0034613 160 0.495
chemotaxis GO:0006935 249 0.480
peptidyl amino acid modification GO:0018193 105 0.465
dorsal closure GO:0007391 79 0.461
neuron fate commitment GO:0048663 50 0.457
single organism cellular localization GO:1902580 180 0.450
branching involved in open tracheal system development GO:0060446 45 0.448
signal transduction by phosphorylation GO:0023014 107 0.441
tube morphogenesis GO:0035239 191 0.441
establishment of localization in cell GO:0051649 402 0.439
compound eye morphogenesis GO:0001745 249 0.438
pigment metabolic process GO:0042440 84 0.434
response to organic substance GO:0010033 284 0.430
positive regulation of developmental process GO:0051094 143 0.427
intracellular protein transport GO:0006886 104 0.425
epidermal growth factor receptor signaling pathway GO:0007173 58 0.424
hindbrain development GO:0030902 2 0.423
protein phosphorylation GO:0006468 169 0.422
actin cytoskeleton organization GO:0030036 206 0.422
axis specification GO:0009798 167 0.414
adherens junction organization GO:0034332 27 0.412
negative regulation of wnt signaling pathway GO:0030178 28 0.411
cellular component assembly involved in morphogenesis GO:0010927 151 0.409
establishment of protein localization to organelle GO:0072594 62 0.408
negative regulation of cell communication GO:0010648 223 0.405
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.403
Mouse Fly
immune system development GO:0002520 57 0.402
ommatidial rotation GO:0016318 20 0.402
programmed cell death GO:0012501 257 0.397
Fly
striated muscle cell differentiation GO:0051146 90 0.397
protein targeting to nucleus GO:0044744 51 0.396
eye photoreceptor cell differentiation GO:0001754 145 0.390
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.389
neuroblast fate determination GO:0007400 12 0.386
regulation of epithelial cell proliferation GO:0050678 4 0.382
regulation of cell cycle GO:0051726 291 0.381
positive regulation of rna biosynthetic process GO:1902680 266 0.381
Mouse Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.379
positive regulation of nucleic acid templated transcription GO:1903508 266 0.370
Mouse Fly
regulation of actin cytoskeleton organization GO:0032956 42 0.364
actin filament based process GO:0030029 220 0.362
lipid metabolic process GO:0006629 121 0.359
regulation of cellular component size GO:0032535 98 0.358
imaginal disc derived appendage development GO:0048737 399 0.354
epithelial structure maintenance GO:0010669 17 0.354
organelle fission GO:0048285 340 0.352
small gtpase mediated signal transduction GO:0007264 88 0.347
cell activation GO:0001775 9 0.344
neuron death GO:0070997 27 0.340
filopodium assembly GO:0046847 33 0.334
positive regulation of cell migration GO:0030335 2 0.328
negative regulation of cell differentiation GO:0045596 143 0.326
cell fate specification GO:0001708 71 0.323
hemopoiesis GO:0030097 46 0.321
positive regulation of protein metabolic process GO:0051247 128 0.319
single organism behavior GO:0044708 391 0.319
response to nutrient levels GO:0031667 114 0.318
positive regulation of cell proliferation GO:0008284 47 0.317
anterior posterior pattern specification GO:0009952 136 0.310
maintenance of protein location in cell GO:0032507 26 0.309
regulation of neuron differentiation GO:0045664 103 0.308
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.303
Mouse Fly
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.303
activation of protein kinase activity GO:0032147 12 0.298
apoptotic process GO:0006915 159 0.295
germarium derived female germ line cyst formation GO:0030727 42 0.295
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.293
establishment of protein localization GO:0045184 163 0.292
nucleocytoplasmic transport GO:0006913 72 0.292
nuclear transport GO:0051169 72 0.292
positive regulation of cellular biosynthetic process GO:0031328 316 0.292
Mouse Fly
peptidyl tyrosine phosphorylation GO:0018108 24 0.289
formation of anatomical boundary GO:0048859 37 0.288
positive regulation of signaling GO:0023056 243 0.285
regulation of erbb signaling pathway GO:1901184 42 0.280
negative regulation of response to extracellular stimulus GO:0032105 6 0.274
synaptic growth at neuromuscular junction GO:0051124 119 0.271
syncytium formation GO:0006949 43 0.270
embryonic digestive tract morphogenesis GO:0048557 4 0.268
regulation of wnt signaling pathway GO:0030111 68 0.264
tracheal outgrowth open tracheal system GO:0007426 18 0.263
positive regulation of intracellular signal transduction GO:1902533 116 0.263
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.263
imaginal disc derived wing morphogenesis GO:0007476 337 0.261
organic acid metabolic process GO:0006082 103 0.261
antimicrobial humoral response GO:0019730 99 0.259
cellular response to dna damage stimulus GO:0006974 223 0.259
regulation of cell proliferation GO:0042127 163 0.258
positive regulation of cell growth GO:0030307 19 0.258
regulation of localization GO:0032879 275 0.257
associative learning GO:0008306 65 0.257
cell recognition GO:0008037 102 0.254
motor neuron axon guidance GO:0008045 58 0.253
single organism intracellular transport GO:1902582 207 0.250
regulation of protein kinase activity GO:0045859 51 0.246
positive regulation of cellular protein metabolic process GO:0032270 118 0.245
positive regulation of phosphorus metabolic process GO:0010562 139 0.241
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.240
regulation of anatomical structure size GO:0090066 163 0.240
positive regulation of protein kinase activity GO:0045860 25 0.238
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.237
regulation of phosphorylation GO:0042325 147 0.235
nephron epithelium development GO:0072009 3 0.235
hair cell differentiation GO:0035315 47 0.232
maintenance of location in cell GO:0051651 28 0.231
response to external biotic stimulus GO:0043207 293 0.230
regulation of cellular amine metabolic process GO:0033238 3 0.229
regulation of cell size GO:0008361 63 0.229
somatic muscle development GO:0007525 66 0.228
germ cell migration GO:0008354 43 0.227
regulation of map kinase activity GO:0043405 17 0.226
cellular amino acid metabolic process GO:0006520 61 0.226
regulation of cellular amino acid metabolic process GO:0006521 0 0.224
cardioblast cell fate specification GO:0042685 9 0.223
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.222
positive regulation of cell motility GO:2000147 3 0.222
nuclear division GO:0000280 332 0.221
cell cell signaling involved in cell fate commitment GO:0045168 210 0.219
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.217
response to extracellular stimulus GO:0009991 116 0.216
apical protein localization GO:0045176 5 0.215
regulation of phosphate metabolic process GO:0019220 210 0.214
embryonic development via the syncytial blastoderm GO:0001700 148 0.210
morphogenesis of embryonic epithelium GO:0016331 94 0.207
response to starvation GO:0042594 97 0.207
wing disc morphogenesis GO:0007472 344 0.206
genital disc development GO:0035215 44 0.206
regulation of neural precursor cell proliferation GO:2000177 35 0.206
gliogenesis GO:0042063 80 0.206
cytoplasmic transport GO:0016482 130 0.204
cellular ketone metabolic process GO:0042180 24 0.204
regulation of cellular protein metabolic process GO:0032268 243 0.202
morphogenesis of a branching epithelium GO:0061138 45 0.201
protein import GO:0017038 55 0.200
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.199
Mouse Fly
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.199
neuron recognition GO:0008038 101 0.198
microtubule anchoring GO:0034453 11 0.198
negative regulation of apoptotic signaling pathway GO:2001234 5 0.195
somatic stem cell maintenance GO:0035019 14 0.194
positive regulation of mapk cascade GO:0043410 63 0.194
negative regulation of response to nutrient levels GO:0032108 6 0.193
muscle fiber development GO:0048747 12 0.192
positive regulation of phosphate metabolic process GO:0045937 139 0.192
epithelial cell migration open tracheal system GO:0007427 32 0.192
notch signaling pathway GO:0007219 120 0.191
cognition GO:0050890 141 0.191
negative regulation of epithelial cell migration GO:0010633 1 0.191
epidermal cell differentiation GO:0009913 51 0.189
sensory perception GO:0007600 196 0.185
locomotory behavior GO:0007626 176 0.185
torc1 signaling GO:0038202 12 0.183
regulation of mapk cascade GO:0043408 92 0.183
anatomical structure homeostasis GO:0060249 97 0.182
dendrite morphogenesis GO:0048813 199 0.182
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.180
neural precursor cell proliferation GO:0061351 75 0.180
positive regulation of phosphorylation GO:0042327 87 0.179
response to transforming growth factor beta GO:0071559 18 0.178
substrate dependent cell migration GO:0006929 3 0.176
humoral immune response GO:0006959 117 0.175
negative regulation of neurogenesis GO:0050768 53 0.175
regulation of cell fate commitment GO:0010453 29 0.174
regulation of secretion GO:0051046 44 0.174
regulation of protein metabolic process GO:0051246 256 0.173
positive regulation of cell development GO:0010720 61 0.173
cellular response to chemical stimulus GO:0070887 199 0.173
erbb signaling pathway GO:0038127 58 0.172
positive regulation of protein tyrosine kinase activity GO:0061098 4 0.172
positive regulation of cellular component biogenesis GO:0044089 80 0.171
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.170
forebrain development GO:0030900 2 0.169
lateral inhibition GO:0046331 206 0.167
small molecule metabolic process GO:0044281 305 0.167
regulation of apoptotic process GO:0042981 130 0.166
trachea development GO:0060438 29 0.165
regulation of cell motility GO:2000145 23 0.164
peptidyl tyrosine modification GO:0018212 24 0.164
response to radiation GO:0009314 155 0.164
compound eye photoreceptor cell differentiation GO:0001751 140 0.163
regulation of cellular response to stress GO:0080135 89 0.163
single organismal cell cell adhesion GO:0016337 45 0.162
cellular response to amino acid stimulus GO:0071230 6 0.162
epithelial cell cell adhesion GO:0090136 6 0.161
regulation of cell differentiation GO:0045595 302 0.159
organelle assembly GO:0070925 198 0.158
regulation of cell cycle process GO:0010564 181 0.153
regulation of cell migration GO:0030334 22 0.152
macromolecular complex assembly GO:0065003 256 0.152
negative regulation of cell fate specification GO:0009996 15 0.152
regulation of cellular component movement GO:0051270 42 0.151
regulation of neuron projection development GO:0010975 69 0.151
regulation of transport GO:0051049 181 0.150
regulation of cell death GO:0010941 173 0.150
body morphogenesis GO:0010171 2 0.149
multi organism behavior GO:0051705 175 0.145
wnt signaling pathway involved in heart development GO:0003306 3 0.144
cell junction organization GO:0034330 57 0.144
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.144
kidney development GO:0001822 3 0.144
photoreceptor cell differentiation GO:0046530 170 0.143
embryonic foregut morphogenesis GO:0048617 3 0.142
stem cell division GO:0017145 69 0.141
camera type eye morphogenesis GO:0048593 2 0.141
positive regulation of cell cycle process GO:0090068 28 0.141
regulation of protein serine threonine kinase activity GO:0071900 25 0.141
positive regulation of protein phosphorylation GO:0001934 34 0.141
regulation of notch signaling pathway GO:0008593 100 0.139
actin filament organization GO:0007015 126 0.138
segmentation GO:0035282 207 0.138
eye antennal disc development GO:0035214 60 0.138
haltere disc development GO:0035216 10 0.137
regulation of tube architecture open tracheal system GO:0035152 68 0.137
regulation of immune response GO:0050776 118 0.135
cell maturation GO:0048469 144 0.134
synapse organization GO:0050808 196 0.133
negative regulation of signaling GO:0023057 219 0.133
malpighian tubule tip cell differentiation GO:0061382 9 0.133
regulation of erk1 and erk2 cascade GO:0070372 39 0.132
female germ line cyst formation GO:0048135 42 0.132
organonitrogen compound metabolic process GO:1901564 318 0.132
appendage development GO:0048736 401 0.132
regulation of apoptotic signaling pathway GO:2001233 10 0.128
positive regulation of programmed cell death GO:0043068 62 0.127
positive regulation of signal transduction GO:0009967 223 0.126
synapse assembly GO:0007416 143 0.126
positive regulation of protein complex assembly GO:0031334 22 0.126
hematopoietic or lymphoid organ development GO:0048534 57 0.126
positive regulation of neuron differentiation GO:0045666 26 0.125
dendrite development GO:0016358 204 0.125
regulation of lipid kinase activity GO:0043550 2 0.124
mating GO:0007618 120 0.123
erk1 and erk2 cascade GO:0070371 39 0.122
regulation of organelle organization GO:0033043 196 0.120
oxoacid metabolic process GO:0043436 103 0.118
amine metabolic process GO:0009308 12 0.117
negative regulation of transcription dna templated GO:0045892 237 0.117
endodermal cell fate commitment GO:0001711 3 0.116
imaginal disc derived wing hair organization GO:0035317 45 0.116
regulation of small gtpase mediated signal transduction GO:0051056 93 0.116
nephron tubule morphogenesis GO:0072078 3 0.116
jak stat cascade GO:0007259 49 0.116
striated muscle cell development GO:0055002 50 0.114
dorsal closure spreading of leading edge cells GO:0007395 4 0.114
formation of organ boundary GO:0010160 30 0.114
organic substance transport GO:0071702 257 0.114
actin filament bundle organization GO:0061572 28 0.114
protein complex assembly GO:0006461 200 0.114
sensory perception of mechanical stimulus GO:0050954 72 0.113
telencephalon development GO:0021537 2 0.113
specification of organ identity GO:0010092 3 0.113
retinal cell programmed cell death GO:0046666 25 0.111
branching morphogenesis of an epithelial tube GO:0048754 45 0.110
homeostatic process GO:0042592 199 0.110
cilium morphogenesis GO:0060271 39 0.110
neuron maturation GO:0042551 31 0.109
cell cell junction organization GO:0045216 55 0.108
organophosphate metabolic process GO:0019637 195 0.107
developmental programmed cell death GO:0010623 138 0.106
Fly
appendage morphogenesis GO:0035107 397 0.106
cell adhesion GO:0007155 136 0.104
regulation of humoral immune response GO:0002920 51 0.103
sex differentiation GO:0007548 81 0.102
negative regulation of signal transduction GO:0009968 206 0.102
regulation of epithelial cell differentiation GO:0030856 4 0.102
regulation of organ growth GO:0046620 42 0.102
tissue homeostasis GO:0001894 36 0.101
striated muscle tissue development GO:0014706 27 0.101
neuron projection extension GO:1990138 32 0.100
regulation of cellular ketone metabolic process GO:0010565 3 0.099
germ line stem cell maintenance GO:0030718 50 0.099
regulation of cell shape GO:0008360 113 0.099
regulation of neuron death GO:1901214 26 0.099
negative regulation of neuron death GO:1901215 18 0.098
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.098
mesoderm development GO:0007498 78 0.097
meiosis i GO:0007127 59 0.097
regulation of protein complex assembly GO:0043254 42 0.097
germ line cyst formation GO:0048134 44 0.096
regulation of protein modification process GO:0031399 112 0.095
negative regulation of multicellular organismal process GO:0051241 142 0.094
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.094
regulation of cellular component biogenesis GO:0044087 201 0.094
cell cycle phase transition GO:0044770 140 0.094
substrate dependent cell migration cell extension GO:0006930 3 0.093
salivary gland morphogenesis GO:0007435 145 0.092
Fly
cellular response to abiotic stimulus GO:0071214 58 0.092
cell death GO:0008219 279 0.092
Fly
canonical wnt signaling pathway GO:0060070 21 0.091
larval development GO:0002164 104 0.090
cardiocyte differentiation GO:0035051 29 0.090
negative regulation of apoptotic process GO:0043066 63 0.090
regulation of cellular localization GO:0060341 136 0.090
regulation of catalytic activity GO:0050790 185 0.089
neuron migration GO:0001764 5 0.089
antimicrobial peptide production GO:0002775 46 0.089
regulation of ras protein signal transduction GO:0046578 93 0.087
endoderm formation GO:0001706 3 0.087
embryonic organ development GO:0048568 50 0.087
cardiac cell fate commitment GO:0060911 17 0.087
learning GO:0007612 75 0.086
negative regulation of mitotic cell cycle GO:0045930 109 0.086
cell fate determination GO:0001709 91 0.086
regulation of organ formation GO:0003156 3 0.085
maintenance of location GO:0051235 73 0.085
cellular amide metabolic process GO:0043603 80 0.084
positive regulation of nervous system development GO:0051962 69 0.084
cellular response to extracellular stimulus GO:0031668 64 0.083
renal filtration cell differentiation GO:0061318 12 0.082
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.081
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.081
heart field specification GO:0003128 0 0.080
regulation of developmental growth GO:0048638 174 0.080
nephron morphogenesis GO:0072028 3 0.079
positive regulation of apoptotic process GO:0043065 47 0.078
negative regulation of nervous system development GO:0051961 92 0.078
skeletal muscle organ development GO:0060538 48 0.078
cellular amine metabolic process GO:0044106 12 0.078
stem cell fate determination GO:0048867 15 0.078
cellular response to nutrient levels GO:0031669 62 0.078
reproductive structure development GO:0048608 74 0.077
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.077
muscle organ development GO:0007517 127 0.076
regulation of cardioblast cell fate specification GO:0042686 8 0.076
embryonic digestive tract development GO:0048566 5 0.075
eye morphogenesis GO:0048592 260 0.075
i kappab phosphorylation GO:0007252 3 0.075
aging GO:0007568 143 0.075
female meiotic division GO:0007143 70 0.074
positive regulation of peptidase activity GO:0010952 29 0.074
positive regulation of protein modification process GO:0031401 58 0.074
regulation of transferase activity GO:0051338 58 0.074
defense response GO:0006952 300 0.074
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.074
meiotic cell cycle process GO:1903046 132 0.073
negative regulation of gene expression GO:0010629 387 0.073
adult behavior GO:0030534 137 0.073
response to inorganic substance GO:0010035 44 0.072
epithelial cell proliferation GO:0050673 15 0.072
single organism membrane organization GO:0044802 93 0.072
regulation of kinase activity GO:0043549 53 0.072
positive regulation of stem cell differentiation GO:2000738 3 0.071
cellular response to growth factor stimulus GO:0071363 30 0.071
negative regulation of intracellular signal transduction GO:1902532 57 0.071
regulation of protein tyrosine kinase activity GO:0061097 9 0.070
regulation of protein phosphorylation GO:0001932 64 0.070
chromosome organization GO:0051276 360 0.070

aop disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.262
cardiovascular system disease DOID:1287 0 0.262
musculoskeletal system disease DOID:17 0 0.149
large intestine cancer DOID:5672 0 0.075
cancer DOID:162 0 0.075
Human
colon cancer DOID:219 0 0.075
disease of cellular proliferation DOID:14566 0 0.075
Human
colorectal cancer DOID:9256 0 0.075
gastrointestinal system cancer DOID:3119 0 0.075
intestinal cancer DOID:10155 0 0.075
organ system cancer DOID:0050686 0 0.075
Human