Drosophila melanogaster

47 known processes

MAN1 (Dmel_CG3167)

CG3167 gene product from transcript CG3167-RA

(Aliases: CG3167,Dmel\CG3167,dMAN1,BcDNA:LD24895)

MAN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.924
brain development GO:0007420 120 0.689
positive regulation of macromolecule metabolic process GO:0010604 405 0.664
positive regulation of rna metabolic process GO:0051254 271 0.658
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.575
enzyme linked receptor protein signaling pathway GO:0007167 179 0.487
response to oxidative stress GO:0006979 86 0.483
regulation of growth GO:0040008 233 0.459
positive regulation of biosynthetic process GO:0009891 316 0.453
locomotory behavior GO:0007626 176 0.441
positive regulation of response to stimulus GO:0048584 323 0.431
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.412
positive regulation of signaling GO:0023056 243 0.406
positive regulation of cell communication GO:0010647 250 0.393
negative regulation of signaling GO:0023057 219 0.383
positive regulation of transcription dna templated GO:0045893 266 0.354
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.323
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.313
embryonic morphogenesis GO:0048598 206 0.262
axonogenesis GO:0007409 290 0.257
axon guidance GO:0007411 233 0.255
dendrite development GO:0016358 204 0.252
negative regulation of signal transduction GO:0009968 206 0.243
ncrna metabolic process GO:0034660 43 0.228
positive regulation of cellular biosynthetic process GO:0031328 316 0.225
imaginal disc derived wing morphogenesis GO:0007476 337 0.222
chromosome organization GO:0051276 360 0.221
establishment of localization in cell GO:0051649 402 0.213
positive regulation of rna biosynthetic process GO:1902680 266 0.211
mrna metabolic process GO:0016071 124 0.208
post embryonic appendage morphogenesis GO:0035120 385 0.208
positive regulation of signal transduction GO:0009967 223 0.196
rna processing GO:0006396 147 0.194
imaginal disc derived wing vein specification GO:0007474 48 0.186
positive regulation of nucleic acid templated transcription GO:1903508 266 0.184
negative regulation of gene expression GO:0010629 387 0.177
regionalization GO:0003002 416 0.174
neuron projection guidance GO:0097485 241 0.173
response to organic substance GO:0010033 284 0.168
axon development GO:0061564 297 0.158
regulation of protein metabolic process GO:0051246 256 0.152
positive regulation of gene expression GO:0010628 290 0.150
chromatin modification GO:0016568 147 0.142
nucleobase containing compound catabolic process GO:0034655 165 0.139
regulation of nervous system development GO:0051960 248 0.136
dendrite morphogenesis GO:0048813 199 0.134
negative regulation of cell communication GO:0010648 223 0.133
negative regulation of cellular metabolic process GO:0031324 382 0.132
positive regulation of intracellular signal transduction GO:1902533 116 0.116
chromatin organization GO:0006325 207 0.114
organic substance catabolic process GO:1901575 308 0.114
embryo development ending in birth or egg hatching GO:0009792 152 0.111
Worm
adult behavior GO:0030534 137 0.109
secretion by cell GO:0032940 101 0.105
cellular catabolic process GO:0044248 372 0.105
regulation of localization GO:0032879 275 0.104
forebrain development GO:0030900 2 0.102
tissue homeostasis GO:0001894 36 0.097
cell motility GO:0048870 251 0.094
Mouse
oocyte differentiation GO:0009994 145 0.087
posttranscriptional regulation of gene expression GO:0010608 145 0.087
transcription from rna polymerase ii promoter GO:0006366 368 0.086
imaginal disc derived appendage development GO:0048737 399 0.083
homeostatic process GO:0042592 199 0.083
cell fate specification GO:0001708 71 0.083
appendage morphogenesis GO:0035107 397 0.080
meiotic cell cycle process GO:1903046 132 0.079
aromatic compound catabolic process GO:0019439 166 0.079
heterocycle catabolic process GO:0046700 166 0.079
wing disc morphogenesis GO:0007472 344 0.076
multicellular organism growth GO:0035264 46 0.074
regulation of neurogenesis GO:0050767 158 0.073
dorsal ventral pattern formation GO:0009953 133 0.073
regulation of transposition GO:0010528 13 0.072
regulation of multicellular organismal development GO:2000026 414 0.071
production of sirna involved in rna interference GO:0030422 11 0.070
circadian rhythm GO:0007623 105 0.070
gene silencing by mirna GO:0035195 22 0.069
central nervous system development GO:0007417 201 0.069
stem cell division GO:0017145 69 0.069
growth GO:0040007 359 0.068
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.068
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.068
carbohydrate derivative metabolic process GO:1901135 217 0.068
cellular macromolecular complex assembly GO:0034622 153 0.066
regulation of neuron projection development GO:0010975 69 0.066
covalent chromatin modification GO:0016569 106 0.065
regulation of cellular localization GO:0060341 136 0.065
bmp signaling pathway GO:0030509 27 0.065
oocyte dorsal ventral axis specification GO:0007310 34 0.064
mrna processing GO:0006397 104 0.063
protein complex biogenesis GO:0070271 201 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.062
spermatogenesis GO:0007283 200 0.062
transposition GO:0032196 13 0.060
regulation of catalytic activity GO:0050790 185 0.060
cell proliferation GO:0008283 299 0.060
tube development GO:0035295 244 0.058
organelle fission GO:0048285 340 0.058
regulation of cell proliferation GO:0042127 163 0.058
protein localization GO:0008104 284 0.054
peptidyl amino acid modification GO:0018193 105 0.054
oxoacid metabolic process GO:0043436 103 0.054
regulation of cellular protein metabolic process GO:0032268 243 0.054
transposition rna mediated GO:0032197 3 0.053
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.052
single organism intracellular transport GO:1902582 207 0.049
posttranscriptional gene silencing by rna GO:0035194 45 0.049
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.047
neurological system process GO:0050877 358 0.047
head development GO:0060322 135 0.045
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.045
regulation of developmental growth GO:0048638 174 0.043
wing disc pattern formation GO:0035222 66 0.042
regulation of cell differentiation GO:0045595 302 0.042
macromolecular complex assembly GO:0065003 256 0.042
centrosome organization GO:0051297 163 0.042
cytoskeleton dependent cytokinesis GO:0061640 81 0.041
Worm
microtubule organizing center organization GO:0031023 168 0.041
immune system process GO:0002376 347 0.041
cellular nitrogen compound catabolic process GO:0044270 165 0.041
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.039
appendage development GO:0048736 401 0.039
cellular protein modification process GO:0006464 438 0.038
regulation of cellular ketone metabolic process GO:0010565 3 0.038
organic acid metabolic process GO:0006082 103 0.038
organonitrogen compound metabolic process GO:1901564 318 0.037
photoreceptor cell differentiation GO:0046530 170 0.036
regulation of neural precursor cell proliferation GO:2000177 35 0.036
connective tissue development GO:0061448 3 0.036
histone modification GO:0016570 106 0.036
chemotaxis GO:0006935 249 0.036
dna metabolic process GO:0006259 227 0.035
regulation of intracellular transport GO:0032386 64 0.034
intracellular protein transport GO:0006886 104 0.033
oocyte development GO:0048599 124 0.033
protein modification process GO:0036211 438 0.033
catabolic process GO:0009056 409 0.032
intracellular signal transduction GO:0035556 300 0.032
cellular macromolecule catabolic process GO:0044265 136 0.032
mitotic nuclear division GO:0007067 213 0.032
tissue morphogenesis GO:0048729 297 0.031
rhythmic process GO:0048511 106 0.031
macromolecule catabolic process GO:0009057 161 0.030
reproductive system development GO:0061458 74 0.030
cytokinesis GO:0000910 90 0.030
Worm
erk1 and erk2 cascade GO:0070371 39 0.030
regulation of neuron differentiation GO:0045664 103 0.030
respiratory system development GO:0060541 213 0.029
gene silencing by rna GO:0031047 57 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
production of small rna involved in gene silencing by rna GO:0070918 15 0.029
negative regulation of phosphate metabolic process GO:0045936 45 0.028
small molecule metabolic process GO:0044281 305 0.028
organelle assembly GO:0070925 198 0.027
mitotic cytokinesis GO:0000281 50 0.027
Worm
posttranscriptional gene silencing GO:0016441 46 0.027
protein targeting GO:0006605 64 0.027
embryonic development via the syncytial blastoderm GO:0001700 148 0.027
regulation of transport GO:0051049 181 0.027
learning or memory GO:0007611 141 0.026
regulation of developmental pigmentation GO:0048070 24 0.026
spindle organization GO:0007051 253 0.025
regulation of ras protein signal transduction GO:0046578 93 0.025
negative regulation of transposition GO:0010529 12 0.025
cognition GO:0050890 141 0.025
meiotic cell cycle GO:0051321 171 0.024
cell migration GO:0016477 238 0.024
Mouse
nitrogen compound transport GO:0071705 85 0.024
compound eye photoreceptor fate commitment GO:0001752 36 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
death GO:0016265 284 0.023
negative regulation of rna metabolic process GO:0051253 251 0.022
reproductive structure development GO:0048608 74 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
centrosome cycle GO:0007098 137 0.022
response to abiotic stimulus GO:0009628 341 0.021
Worm
organic substance transport GO:0071702 257 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
digestive tract morphogenesis GO:0048546 127 0.021
peptidyl threonine phosphorylation GO:0018107 2 0.021
rna 3 end processing GO:0031123 45 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
negative regulation of protein metabolic process GO:0051248 85 0.020
response to other organism GO:0051707 293 0.020
nuclear import GO:0051170 51 0.020
response to organic cyclic compound GO:0014070 89 0.020
protein complex assembly GO:0006461 200 0.020
regulation of protein catabolic process GO:0042176 55 0.020
cellular homeostasis GO:0019725 80 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
negative regulation of developmental process GO:0051093 201 0.019
developmental growth GO:0048589 280 0.019
meiotic nuclear division GO:0007126 151 0.019
protein transport GO:0015031 155 0.019
cellular protein localization GO:0034613 160 0.018
striated muscle myosin thick filament assembly GO:0071688 3 0.018
regulation of secretion by cell GO:1903530 39 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
cellular response to nutrient GO:0031670 1 0.018
single organism cellular localization GO:1902580 180 0.018
positive regulation of developmental process GO:0051094 143 0.018
germline stem cell asymmetric division GO:0098728 15 0.018
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.017
compound eye development GO:0048749 307 0.017
axis specification GO:0009798 167 0.017
taxis GO:0042330 304 0.017
regulation of erbb signaling pathway GO:1901184 42 0.017
nuclear division GO:0000280 332 0.017
secretion GO:0046903 109 0.017
male gamete generation GO:0048232 201 0.017
intracellular transport GO:0046907 228 0.017
histone mrna metabolic process GO:0008334 8 0.017
cellular ketone metabolic process GO:0042180 24 0.017
regulation of cell cycle GO:0051726 291 0.016
Mouse
myofibril assembly GO:0030239 36 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
ribonucleoprotein complex assembly GO:0022618 23 0.016
regulation of programmed cell death GO:0043067 152 0.016
stem cell differentiation GO:0048863 117 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
eye morphogenesis GO:0048592 260 0.016
cellular response to organic cyclic compound GO:0071407 32 0.016
regulation of erk1 and erk2 cascade GO:0070372 39 0.016
regulation of multi organism process GO:0043900 131 0.015
purine containing compound metabolic process GO:0072521 155 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
cell death GO:0008219 279 0.015
negative regulation of nervous system development GO:0051961 92 0.015
gene silencing GO:0016458 138 0.015
protein phosphorylation GO:0006468 169 0.015
digestive tract development GO:0048565 149 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
vesicle mediated transport GO:0016192 381 0.015
development of primary sexual characteristics GO:0045137 50 0.015
protein targeting to nucleus GO:0044744 51 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
establishment of protein localization GO:0045184 163 0.015
purine nucleotide metabolic process GO:0006163 146 0.014
cell aging GO:0007569 2 0.014
multicellular organismal homeostasis GO:0048871 41 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
circadian regulation of gene expression GO:0032922 5 0.014
regulation of response to stress GO:0080134 200 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
regulation of secretion GO:0051046 44 0.013
negative regulation of cell death GO:0060548 81 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
gonad development GO:0008406 50 0.013
body morphogenesis GO:0010171 2 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
response to oxygen containing compound GO:1901700 200 0.013
developmental pigmentation GO:0048066 68 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
protein localization to organelle GO:0033365 82 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
positive regulation of growth GO:0045927 75 0.013
single organism biosynthetic process GO:0044711 206 0.013
positive regulation of cell differentiation GO:0045597 64 0.013
wound healing GO:0042060 75 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
telencephalon development GO:0021537 2 0.012
positive regulation of protein catabolic process GO:0045732 34 0.012
single organism nuclear import GO:1902593 51 0.012
localization of cell GO:0051674 257 0.012
Mouse
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of translation GO:0006417 56 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
regulation of neuroblast proliferation GO:1902692 34 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of cell development GO:0060284 215 0.012
cellular response to oxidative stress GO:0034599 28 0.012
regulation of immune system process GO:0002682 176 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
mushroom body development GO:0016319 70 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
erbb signaling pathway GO:0038127 58 0.011
neuron fate commitment GO:0048663 50 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
histone lysine demethylation GO:0070076 6 0.011
defense response GO:0006952 300 0.011
maintenance of gastrointestinal epithelium GO:0030277 3 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.011
organelle inheritance GO:0048308 2 0.011
single organism catabolic process GO:0044712 228 0.011
chromatin remodeling GO:0006338 72 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
chromosome segregation GO:0007059 157 0.011
Worm
ovarian follicle cell development GO:0030707 248 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
regulation of protein serine threonine kinase activity GO:0071900 25 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
eye development GO:0001654 323 0.011
muscle structure development GO:0061061 224 0.010
Mouse
cellular response to organic substance GO:0071310 132 0.010
amine metabolic process GO:0009308 12 0.010
ncrna processing GO:0034470 30 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
response to radiation GO:0009314 155 0.010
Worm
regulation of transposition rna mediated GO:0010525 3 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
sex differentiation GO:0007548 81 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
stem cell proliferation GO:0072089 88 0.010
carboxylic acid metabolic process GO:0019752 92 0.010
epithelial cell differentiation GO:0030855 322 0.010

MAN1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.169
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
eye disease DOID:5614 0 0.010