Drosophila melanogaster

170 known processes

Socs36E (Dmel_CG15154)

Suppressor of cytokine signaling at 36E

(Aliases: dmSocs36E,clone 2.2,dSOCS,socs60E1,anon-EST:Liang-2.2,Socs,CG15154,Dmel\CG15154,SOCS,socs36E,SOCS36E)

Socs36E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial cell migration GO:0010631 148 0.969
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.952
tissue migration GO:0090130 155 0.894
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.834
phosphorylation GO:0016310 294 0.832
Human
regulation of protein metabolic process GO:0051246 256 0.825
Human
localization of cell GO:0051674 257 0.807
imaginal disc derived appendage morphogenesis GO:0035114 395 0.761
regulation of erbb signaling pathway GO:1901184 42 0.754
negative regulation of response to stimulus GO:0048585 258 0.751
negative regulation of biosynthetic process GO:0009890 277 0.748
border follicle cell migration GO:0007298 113 0.708
negative regulation of gene expression GO:0010629 387 0.706
epithelium migration GO:0090132 148 0.687
columnar cuboidal epithelial cell development GO:0002066 249 0.676
ovarian follicle cell development GO:0030707 248 0.661
wing disc morphogenesis GO:0007472 344 0.651
appendage morphogenesis GO:0035107 397 0.620
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.619
ovarian follicle cell migration GO:0007297 121 0.592
regulation of phosphate metabolic process GO:0019220 210 0.590
Human
protein phosphorylation GO:0006468 169 0.588
Human
negative regulation of transcription dna templated GO:0045892 237 0.587
imaginal disc derived wing morphogenesis GO:0007476 337 0.578
cell motility GO:0048870 251 0.551
erbb signaling pathway GO:0038127 58 0.547
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.542
enzyme linked receptor protein signaling pathway GO:0007167 179 0.540
negative regulation of cellular metabolic process GO:0031324 382 0.540
Human
positive regulation of rna metabolic process GO:0051254 271 0.520
negative regulation of cell communication GO:0010648 223 0.519
cellular protein modification process GO:0006464 438 0.516
Human
intracellular signal transduction GO:0035556 300 0.512
ameboidal type cell migration GO:0001667 151 0.506
regulation of protein tyrosine kinase activity GO:0061097 9 0.497
Human
imaginal disc derived appendage development GO:0048737 399 0.490
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.470
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.466
negative regulation of erbb signaling pathway GO:1901185 29 0.453
protein modification process GO:0036211 438 0.430
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.427
cell migration GO:0016477 238 0.418
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.417
negative regulation of signal transduction GO:0009968 206 0.417
r7 cell differentiation GO:0045466 43 0.395
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.382
negative regulation of rna metabolic process GO:0051253 251 0.380
amine metabolic process GO:0009308 12 0.368
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.364
learning or memory GO:0007611 141 0.359
regulation of phosphorus metabolic process GO:0051174 210 0.348
Human
compound eye development GO:0048749 307 0.345
cellular amine metabolic process GO:0044106 12 0.344
appendage development GO:0048736 401 0.343
cognition GO:0050890 141 0.340
transcription from rna polymerase ii promoter GO:0006366 368 0.332
response to glucose GO:0009749 2 0.329
negative regulation of cellular biosynthetic process GO:0031327 277 0.328
regulation of cellular protein metabolic process GO:0032268 243 0.324
Human
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.324
Human
regulation of molecular function GO:0065009 217 0.321
Human
epithelial cell development GO:0002064 274 0.319
regulation of intracellular signal transduction GO:1902531 236 0.319
morphogenesis of an epithelium GO:0002009 276 0.314
positive regulation of catalytic activity GO:0043085 118 0.311
eye development GO:0001654 323 0.306
signal transduction by phosphorylation GO:0023014 107 0.306
negative regulation of rna biosynthetic process GO:1902679 240 0.302
epidermal growth factor receptor signaling pathway GO:0007173 58 0.301
neurological system process GO:0050877 358 0.301
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.299
organonitrogen compound metabolic process GO:1901564 318 0.298
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.291
cellular macromolecule localization GO:0070727 220 0.282
immune system process GO:0002376 347 0.280
Mouse
embryonic morphogenesis GO:0048598 206 0.277
ommatidial rotation GO:0016318 20 0.276
learning GO:0007612 75 0.273
defense response GO:0006952 300 0.273
spermatogenesis GO:0007283 200 0.272
regulation of phosphorylation GO:0042325 147 0.268
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.266
Human
positive regulation of biosynthetic process GO:0009891 316 0.260
positive regulation of transcription dna templated GO:0045893 266 0.260
negative regulation of nucleic acid templated transcription GO:1903507 240 0.258
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.253
epithelial cell differentiation GO:0030855 322 0.251
cellular amino acid metabolic process GO:0006520 61 0.234
protein localization to organelle GO:0033365 82 0.234
positive regulation of molecular function GO:0044093 136 0.234
negative regulation of signaling GO:0023057 219 0.231
mitotic cytokinesis GO:0000281 50 0.222
r7 cell fate commitment GO:0007465 12 0.220
protein maturation GO:0051604 71 0.215
positive regulation of gene expression GO:0010628 290 0.213
malpighian tubule development GO:0072002 64 0.212
regulation of response to stress GO:0080134 200 0.210
regulation of protein kinase activity GO:0045859 51 0.209
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.205
regulation of immune system process GO:0002682 176 0.198
Mouse
regulation of embryonic development GO:0045995 68 0.196
regionalization GO:0003002 416 0.194
regulation of organ morphogenesis GO:2000027 78 0.194
mapk cascade GO:0000165 107 0.193
chromatin modification GO:0016568 147 0.192
chromosome organization GO:0051276 360 0.191
regulation of protein modification process GO:0031399 112 0.189
Human
negative regulation of immune system process GO:0002683 50 0.187
Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.182
associative learning GO:0008306 65 0.181
small molecule metabolic process GO:0044281 305 0.177
cell division GO:0051301 248 0.177
tissue morphogenesis GO:0048729 297 0.176
tube morphogenesis GO:0035239 191 0.174
positive regulation of macromolecule metabolic process GO:0010604 405 0.173
Human
regulation of r7 cell differentiation GO:0045676 15 0.173
positive regulation of signaling GO:0023056 243 0.170
Fly
positive regulation of response to stimulus GO:0048584 323 0.169
Mouse Fly
negative regulation of phosphorylation GO:0042326 35 0.168
Human
compound eye photoreceptor cell differentiation GO:0001751 140 0.167
positive regulation of protein metabolic process GO:0051247 128 0.166
Human
positive regulation of cellular protein metabolic process GO:0032270 118 0.165
Human
response to abiotic stimulus GO:0009628 341 0.163
negative regulation of cellular protein metabolic process GO:0032269 85 0.163
Human
hematopoietic or lymphoid organ development GO:0048534 57 0.159
Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.159
heart process GO:0003015 37 0.156
single organism nuclear import GO:1902593 51 0.156
positive regulation of cell migration GO:0030335 2 0.156
intracellular transport GO:0046907 228 0.154
eye photoreceptor cell fate commitment GO:0042706 37 0.153
positive regulation of phosphate metabolic process GO:0045937 139 0.153
positive regulation of phosphorylation GO:0042327 87 0.147
tube development GO:0035295 244 0.146
response to external biotic stimulus GO:0043207 293 0.143
photoreceptor cell fate commitment GO:0046552 41 0.143
response to alcohol GO:0097305 95 0.140
negative regulation of phosphate metabolic process GO:0045936 45 0.140
Human
response to other organism GO:0051707 293 0.139
regulation of cysteine type endopeptidase activity GO:2000116 27 0.139
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.138
Human
response to monosaccharide GO:0034284 4 0.137
regulation of immune response GO:0050776 118 0.137
Mouse
cellular response to chemical stimulus GO:0070887 199 0.136
Mouse
cellular protein localization GO:0034613 160 0.135
post embryonic appendage morphogenesis GO:0035120 385 0.135
response to oxidative stress GO:0006979 86 0.135
carbohydrate derivative biosynthetic process GO:1901137 85 0.135
regulation of cellular ketone metabolic process GO:0010565 3 0.134
positive regulation of nucleic acid templated transcription GO:1903508 266 0.132
peptidyl amino acid modification GO:0018193 105 0.131
Human
imaginal disc derived wing vein specification GO:0007474 48 0.130
negative regulation of cell cycle phase transition GO:1901988 103 0.130
cellular response to dna damage stimulus GO:0006974 223 0.130
positive regulation of rna biosynthetic process GO:1902680 266 0.129
positive regulation of cell communication GO:0010647 250 0.127
Fly
oxoacid metabolic process GO:0043436 103 0.126
olfactory learning GO:0008355 56 0.125
spermatid development GO:0007286 98 0.125
cellular response to lipopolysaccharide GO:0071222 3 0.124
protein localization to nucleus GO:0034504 55 0.122
proteolysis GO:0006508 192 0.121
Human
regulation of peptidase activity GO:0052547 39 0.119
defense response to other organism GO:0098542 225 0.119
regulation of cell proliferation GO:0042127 163 0.118
protein processing GO:0016485 68 0.118
long term memory GO:0007616 62 0.115
regulation of transferase activity GO:0051338 58 0.115
Human
single organism intracellular transport GO:1902582 207 0.114
organic substance transport GO:0071702 257 0.110
regulation of localization GO:0032879 275 0.108
cell cycle checkpoint GO:0000075 95 0.108
gland morphogenesis GO:0022612 145 0.108
hindgut morphogenesis GO:0007442 58 0.108
mesoderm development GO:0007498 78 0.105
mitotic cell cycle checkpoint GO:0007093 88 0.104
single organism cellular localization GO:1902580 180 0.103
peptidyl tyrosine modification GO:0018212 24 0.103
Human
small gtpase mediated signal transduction GO:0007264 88 0.102
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.102
regulation of defense response GO:0031347 102 0.102
negative regulation of kinase activity GO:0033673 16 0.100
Human
embryonic development via the syncytial blastoderm GO:0001700 148 0.100
photoreceptor cell differentiation GO:0046530 170 0.100
cellular response to organic substance GO:0071310 132 0.099
Mouse
respiratory system development GO:0060541 213 0.097
negative regulation of protein metabolic process GO:0051248 85 0.097
Human
gland development GO:0048732 191 0.096
response to organic substance GO:0010033 284 0.096
Mouse
response to oxygen containing compound GO:1901700 200 0.096
bmp signaling pathway GO:0030509 27 0.096
central nervous system development GO:0007417 201 0.096
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.095
eye antennal disc development GO:0035214 60 0.094
regulation of multicellular organismal development GO:2000026 414 0.093
regulation of cell cycle GO:0051726 291 0.093
regulation of cellular component biogenesis GO:0044087 201 0.091
single organism biosynthetic process GO:0044711 206 0.090
regulation of kinase activity GO:0043549 53 0.090
Human
carbohydrate derivative metabolic process GO:1901135 217 0.089
response to paraquat GO:1901562 4 0.088
covalent chromatin modification GO:0016569 106 0.087
dorsal ventral pattern formation GO:0009953 133 0.087
nucleoside phosphate metabolic process GO:0006753 162 0.085
regulation of mapk cascade GO:0043408 92 0.084
negative regulation of cell cycle process GO:0010948 109 0.084
ribonucleotide metabolic process GO:0009259 145 0.082
positive regulation of protein modification process GO:0031401 58 0.081
establishment of localization in cell GO:0051649 402 0.080
exocrine system development GO:0035272 162 0.080
digestive tract morphogenesis GO:0048546 127 0.079
regulation of epidermal growth factor activated receptor activity GO:0007176 4 0.079
Human
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.079
cell death GO:0008219 279 0.077
stem cell differentiation GO:0048863 117 0.076
negative regulation of protein phosphorylation GO:0001933 17 0.076
Human
regulation of cell development GO:0060284 215 0.075
salivary gland development GO:0007431 162 0.074
cellular ketone metabolic process GO:0042180 24 0.074
nucleocytoplasmic transport GO:0006913 72 0.074
peptidyl tyrosine phosphorylation GO:0018108 24 0.073
Human
regulation of endopeptidase activity GO:0052548 36 0.073
rhythmic process GO:0048511 106 0.073
circadian behavior GO:0048512 76 0.073
regulation of cellular amine metabolic process GO:0033238 3 0.073
response to hexose GO:0009746 3 0.071
regulation of anatomical structure morphogenesis GO:0022603 242 0.070
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.070
eggshell formation GO:0030703 105 0.070
vesicle mediated transport GO:0016192 381 0.069
forebrain development GO:0030900 2 0.069
hemocyte differentiation GO:0042386 38 0.069
multicellular organismal aging GO:0010259 140 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.068
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.068
regulation of protein phosphorylation GO:0001932 64 0.068
Human
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.067
regulation of purine nucleotide metabolic process GO:1900542 62 0.067
rhythmic behavior GO:0007622 76 0.066
negative regulation of intracellular signal transduction GO:1902532 57 0.066
embryonic hindgut morphogenesis GO:0048619 48 0.066
single organismal cell cell adhesion GO:0016337 45 0.065
cytokinesis GO:0000910 90 0.065
protein import into nucleus GO:0006606 51 0.064
nuclear import GO:0051170 51 0.064
protein ubiquitination GO:0016567 70 0.064
histone modification GO:0016570 106 0.063
purine nucleotide metabolic process GO:0006163 146 0.063
response to growth factor GO:0070848 31 0.063
purine nucleotide catabolic process GO:0006195 109 0.062
response to biotic stimulus GO:0009607 294 0.062
glycosyl compound metabolic process GO:1901657 127 0.062
response to endogenous stimulus GO:0009719 119 0.062
cytoplasmic transport GO:0016482 130 0.061
protein targeting to nucleus GO:0044744 51 0.061
regulation of proteolysis GO:0030162 87 0.061
Human
cytoskeleton dependent cytokinesis GO:0061640 81 0.061
immune system development GO:0002520 57 0.060
Mouse
regulation of canonical wnt signaling pathway GO:0060828 15 0.060
innate immune response GO:0045087 144 0.060
male gamete generation GO:0048232 201 0.060
open tracheal system development GO:0007424 204 0.059
catabolic process GO:0009056 409 0.059
Human
response to ionizing radiation GO:0010212 32 0.059
aging GO:0007568 143 0.058
cell proliferation GO:0008283 299 0.058
response to bacterium GO:0009617 198 0.057
establishment of protein localization GO:0045184 163 0.056
organic acid metabolic process GO:0006082 103 0.056
positive regulation of lipid metabolic process GO:0045834 4 0.056
eye morphogenesis GO:0048592 260 0.056
developmental programmed cell death GO:0010623 138 0.056
erk1 and erk2 cascade GO:0070371 39 0.055
regulation of intracellular protein transport GO:0033157 46 0.055
purine ribonucleoside metabolic process GO:0046128 127 0.054
stress activated mapk cascade GO:0051403 52 0.054
programmed cell death GO:0012501 257 0.054
positive regulation of protein secretion GO:0050714 9 0.054
regulation of small gtpase mediated signal transduction GO:0051056 93 0.053
protein import GO:0017038 55 0.052
positive regulation of r7 cell differentiation GO:0045678 7 0.052
positive regulation of cell development GO:0010720 61 0.052
negative regulation of immune response GO:0050777 39 0.052
Mouse
carboxylic acid metabolic process GO:0019752 92 0.051
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.051
establishment of ommatidial planar polarity GO:0042067 49 0.051
regulation of cellular component movement GO:0051270 42 0.051
intracellular protein transport GO:0006886 104 0.051
positive regulation of cellular amine metabolic process GO:0033240 0 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
response to lipopolysaccharide GO:0032496 4 0.050
positive regulation of transport GO:0051050 92 0.050
negative regulation of phosphorus metabolic process GO:0010563 45 0.049
Human
tor signaling GO:0031929 32 0.049
Fly
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.049
protein complex assembly GO:0006461 200 0.049
actin filament based process GO:0030029 220 0.048
regulation of catalytic activity GO:0050790 185 0.048
Human
immune effector process GO:0002252 98 0.048
Mouse
digestive tract development GO:0048565 149 0.048
larval development GO:0002164 104 0.048
synapse assembly GO:0007416 143 0.047
stem cell fate commitment GO:0048865 25 0.047
transmembrane transport GO:0055085 139 0.047
regulation of actin cytoskeleton organization GO:0032956 42 0.047
regulation of wnt signaling pathway GO:0030111 68 0.047
embryonic organ development GO:0048568 50 0.046
chromatin organization GO:0006325 207 0.046
regulation of cellular response to growth factor stimulus GO:0090287 13 0.046
regulation of ras protein signal transduction GO:0046578 93 0.046
mitotic nuclear division GO:0007067 213 0.046
negative regulation of cell cycle GO:0045786 116 0.045
genital disc development GO:0035215 44 0.045
organophosphate metabolic process GO:0019637 195 0.045
positive regulation of protein transport GO:0051222 37 0.045
negative regulation of molecular function GO:0044092 51 0.044
Human
single organism behavior GO:0044708 391 0.044
response to transforming growth factor beta GO:0071559 18 0.044
chemosensory behavior GO:0007635 106 0.044
defense response to fungus GO:0050832 48 0.044
imaginal disc pattern formation GO:0007447 91 0.044
dna replication GO:0006260 48 0.043
regulation of map kinase activity GO:0043405 17 0.043
positive regulation of signal transduction GO:0009967 223 0.043
Fly
anatomical structure homeostasis GO:0060249 97 0.043
cellular response to radiation GO:0071478 52 0.042
gene silencing GO:0016458 138 0.042
positive regulation of peptidase activity GO:0010952 29 0.042
eye photoreceptor cell differentiation GO:0001754 145 0.042
positive regulation of cell differentiation GO:0045597 64 0.042
Mouse
g protein coupled receptor signaling pathway GO:0007186 136 0.041
circadian sleep wake cycle process GO:0022410 24 0.041
chorion containing eggshell formation GO:0007304 105 0.041
apoptotic process GO:0006915 159 0.041
regulation of transport GO:0051049 181 0.040
regulation of cell death GO:0010941 173 0.040
axon target recognition GO:0007412 16 0.040
positive regulation of cellular component biogenesis GO:0044089 80 0.040
chromatin remodeling GO:0006338 72 0.040
sex determination GO:0007530 18 0.040
nucleotide metabolic process GO:0009117 161 0.040
organonitrogen compound biosynthetic process GO:1901566 117 0.040
regulation of cell morphogenesis GO:0022604 163 0.040
muscle system process GO:0003012 21 0.040
negative regulation of cell differentiation GO:0045596 143 0.040
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.039
positive regulation of mapk cascade GO:0043410 63 0.039
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 9 0.039
protein localization GO:0008104 284 0.038
stress activated protein kinase signaling cascade GO:0031098 55 0.038
regulation of mitotic cell cycle phase transition GO:1901990 130 0.038
germarium derived female germ line cyst encapsulation GO:0030708 8 0.038
macromolecule catabolic process GO:0009057 161 0.038
Human
autophagic cell death GO:0048102 83 0.038
wnt signaling pathway GO:0016055 98 0.038
cell cell signaling involved in cell fate commitment GO:0045168 210 0.038
retina development in camera type eye GO:0060041 4 0.038
hindgut development GO:0061525 58 0.038
determination of imaginal disc primordium GO:0007445 11 0.038
regulation of cellular localization GO:0060341 136 0.037
negative regulation of catalytic activity GO:0043086 42 0.037
Human
mitotic cell cycle phase transition GO:0044772 138 0.037
dna damage checkpoint GO:0000077 78 0.037
sensory organ morphogenesis GO:0090596 260 0.037
multi multicellular organism process GO:0044706 123 0.036
regulation of nucleocytoplasmic transport GO:0046822 35 0.036
circadian sleep wake cycle sleep GO:0050802 23 0.036
regulation of protein serine threonine kinase activity GO:0071900 25 0.036
positive regulation of organelle organization GO:0010638 65 0.035
regulation of apoptotic signaling pathway GO:2001233 10 0.035
regulation of cell differentiation GO:0045595 302 0.035
peptidyl threonine phosphorylation GO:0018107 2 0.035
salivary gland morphogenesis GO:0007435 145 0.035
spermatid differentiation GO:0048515 114 0.034
morphogenesis of a polarized epithelium GO:0001738 93 0.034
positive regulation of protein phosphorylation GO:0001934 34 0.034
urogenital system development GO:0001655 72 0.034
regulation of protein localization GO:0032880 76 0.034
cellular protein catabolic process GO:0044257 83 0.034
Human
malpighian tubule morphogenesis GO:0007443 44 0.033
regulation of cell shape GO:0008360 113 0.033
positive regulation of apoptotic signaling pathway GO:2001235 4 0.033
nucleoside triphosphate metabolic process GO:0009141 120 0.033
protein heterooligomerization GO:0051291 4 0.033
positive regulation of hydrolase activity GO:0051345 78 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
olfactory behavior GO:0042048 97 0.033
determination of adult lifespan GO:0008340 137 0.033
morphogenesis of follicular epithelium GO:0016333 36 0.033
organic substance catabolic process GO:1901575 308 0.033
Human
protein targeting GO:0006605 64 0.033
glycoprotein metabolic process GO:0009100 41 0.032
salivary gland cell autophagic cell death GO:0035071 83 0.032
response to radiation GO:0009314 155 0.032
positive regulation of gtpase activity GO:0043547 43 0.032
response to ketone GO:1901654 34 0.032
regulation of photoreceptor cell differentiation GO:0046532 34 0.032
regulation of protein transport GO:0051223 57 0.032
cell junction assembly GO:0034329 42 0.032
ras protein signal transduction GO:0007265 88 0.032
regulation of actin filament based process GO:0032970 42 0.031
gastrulation GO:0007369 70 0.031
stem cell proliferation GO:0072089 88 0.031
purine containing compound catabolic process GO:0072523 112 0.031
cellular catabolic process GO:0044248 372 0.031
Human
regulation of receptor activity GO:0010469 10 0.031
Human
regulation of cell cycle process GO:0010564 181 0.031
nuclear transport GO:0051169 72 0.031
positive regulation of proteolysis GO:0045862 52 0.031
Human
digestive system development GO:0055123 149 0.031
immune response GO:0006955 246 0.030
Mouse
regulation of cellular response to stress GO:0080135 89 0.030
negative regulation of cell proliferation GO:0008285 69 0.030
cell cell junction organization GO:0045216 55 0.030
gtp catabolic process GO:0006184 72 0.029
regulation of cytoskeleton organization GO:0051493 89 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.029
connective tissue development GO:0061448 3 0.029
response to wounding GO:0009611 94 0.029
regulation of stem cell proliferation GO:0072091 40 0.029
circulatory system process GO:0003013 37 0.029
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.028
regulation of organelle organization GO:0033043 196 0.028
dna integrity checkpoint GO:0031570 81 0.028
positive regulation of endopeptidase activity GO:0010950 26 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.028
inositol lipid mediated signaling GO:0048017 4 0.027
negative regulation of mitotic cell cycle GO:0045930 109 0.027
mitotic dna integrity checkpoint GO:0044774 75 0.027
myotube cell development GO:0014904 3 0.027
regulation of cytoplasmic transport GO:1903649 47 0.027
negative regulation of wnt signaling pathway GO:0030178 28 0.027
kidney development GO:0001822 3 0.027
immune response activating signal transduction GO:0002757 2 0.027
positive regulation of cellular component organization GO:0051130 156 0.027
ribose phosphate metabolic process GO:0019693 145 0.027
epithelial structure maintenance GO:0010669 17 0.026
actin filament organization GO:0007015 126 0.026
positive regulation of transferase activity GO:0051347 26 0.026
cellular response to endogenous stimulus GO:0071495 80 0.026
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.026
Human
endocytosis GO:0006897 310 0.026
protein modification by small protein conjugation GO:0032446 79 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
camera type eye development GO:0043010 4 0.026
jnk cascade GO:0007254 50 0.026
single organism carbohydrate metabolic process GO:0044723 72 0.026
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.026
determination of genital disc primordium GO:0035225 10 0.026
chromatin silencing GO:0006342 76 0.026
nucleotide catabolic process GO:0009166 109 0.025
immune response regulating signaling pathway GO:0002764 2 0.025
negative regulation of protein processing GO:0010955 31 0.025
regulation of nucleotide metabolic process GO:0006140 62 0.025
regulation of response to external stimulus GO:0032101 115 0.025
actin cytoskeleton organization GO:0030036 206 0.025
positive regulation of developmental process GO:0051094 143 0.025
Mouse
circadian sleep wake cycle GO:0042745 28 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
regulation of bmp signaling pathway GO:0030510 23 0.025
compound eye photoreceptor fate commitment GO:0001752 36 0.025
regulation of programmed cell death GO:0043067 152 0.025
protein transport GO:0015031 155 0.025
positive regulation of exocytosis GO:0045921 4 0.025
regulation of epithelial cell proliferation GO:0050678 4 0.024
heterocycle catabolic process GO:0046700 166 0.024
compound eye morphogenesis GO:0001745 249 0.024
regulation of erk1 and erk2 cascade GO:0070372 39 0.024
regulation of embryonic cell shape GO:0016476 30 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.024
negative regulation of defense response GO:0031348 35 0.024
camera type eye morphogenesis GO:0048593 2 0.024
purine containing compound metabolic process GO:0072521 155 0.024
ion transmembrane transport GO:0034220 122 0.024
establishment of protein localization to organelle GO:0072594 62 0.023
regulation of cell adhesion GO:0030155 27 0.023
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.023
carbohydrate biosynthetic process GO:0016051 17 0.023
response to fungus GO:0009620 50 0.023
telomere maintenance GO:0000723 21 0.023
hemocyte migration GO:0035099 19 0.023
cellular response to nitrogen compound GO:1901699 51 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
Mouse
regulation of hydrolase activity GO:0051336 97 0.023
purine nucleoside triphosphate catabolic process GO:0009146 108 0.023
circadian rhythm GO:0007623 105 0.023
head development GO:0060322 135 0.022
renal system development GO:0072001 72 0.022
regulation of cell motility GO:2000145 23 0.022
cellular response to biotic stimulus GO:0071216 4 0.022

Socs36E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
sensory system disease DOID:0050155 0 0.025
disease of anatomical entity DOID:7 0 0.025
eye and adnexa disease DOID:1492 0 0.025
nervous system disease DOID:863 0 0.025