Drosophila melanogaster

15 known processes

Hlc (Dmel_CG1666)

Helicase

(Aliases: l(1)11P1,A112,14,l(1)S-19F6,hlc,l(1)19Ff,HM-44,7,l(1)A112,Dmel\CG1666,DmRH10,11P1,lA112,CG1666,l11P1,HLC,l(1)8-1)

Hlc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite development GO:0016358 204 0.483
rrna processing GO:0006364 3 0.442
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.430
gliogenesis GO:0042063 80 0.361
lipid localization GO:0010876 54 0.350
dendrite morphogenesis GO:0048813 199 0.240
endocytosis GO:0006897 310 0.143
posttranscriptional regulation of gene expression GO:0010608 145 0.139
regulation of gene expression epigenetic GO:0040029 128 0.139
rna interference GO:0016246 27 0.137
lipid storage GO:0019915 38 0.131
regulation of neurogenesis GO:0050767 158 0.111
determination of adult lifespan GO:0008340 137 0.105
positive regulation of signaling GO:0023056 243 0.103
aging GO:0007568 143 0.101
macromolecular complex assembly GO:0065003 256 0.100
multicellular organismal aging GO:0010259 140 0.097
vesicle mediated transport GO:0016192 381 0.096
positive regulation of nucleic acid templated transcription GO:1903508 266 0.095
positive regulation of macromolecule metabolic process GO:0010604 405 0.095
secretion GO:0046903 109 0.091
mitotic nuclear division GO:0007067 213 0.087
development of primary sexual characteristics GO:0045137 50 0.085
ribosomal large subunit biogenesis GO:0042273 1 0.083
Yeast
neuroblast proliferation GO:0007405 74 0.083
posttranscriptional gene silencing GO:0016441 46 0.082
eye photoreceptor cell differentiation GO:0001754 145 0.077
translation GO:0006412 69 0.077
regulation of localization GO:0032879 275 0.073
localization of cell GO:0051674 257 0.072
response to temperature stimulus GO:0009266 106 0.071
regulation of cellular localization GO:0060341 136 0.071
nuclear division GO:0000280 332 0.068
meiotic dna double strand break formation GO:0042138 1 0.068
larval development GO:0002164 104 0.067
locomotory behavior GO:0007626 176 0.067
positive regulation of gene expression GO:0010628 290 0.065
cellular macromolecular complex assembly GO:0034622 153 0.064
organelle fission GO:0048285 340 0.061
ncrna metabolic process GO:0034660 43 0.060
Yeast
muscle organ development GO:0007517 127 0.059
positive regulation of cell communication GO:0010647 250 0.058
posttranscriptional gene silencing by rna GO:0035194 45 0.058
translational initiation GO:0006413 11 0.056
body morphogenesis GO:0010171 2 0.056
positive regulation of response to stimulus GO:0048584 323 0.054
cellular amino acid metabolic process GO:0006520 61 0.051
actin filament based process GO:0030029 220 0.049
cell death GO:0008219 279 0.049
positive regulation of rna biosynthetic process GO:1902680 266 0.046
eye development GO:0001654 323 0.046
ras protein signal transduction GO:0007265 88 0.044
muscle structure development GO:0061061 224 0.044
lipid metabolic process GO:0006629 121 0.043
tissue morphogenesis GO:0048729 297 0.043
regulation of nervous system development GO:0051960 248 0.042
sex differentiation GO:0007548 81 0.041
erk1 and erk2 cascade GO:0070371 39 0.041
muscle cell differentiation GO:0042692 103 0.041
phagocytosis GO:0006909 215 0.041
response to biotic stimulus GO:0009607 294 0.040
positive regulation of signal transduction GO:0009967 223 0.039
gonad development GO:0008406 50 0.038
reproductive system development GO:0061458 74 0.036
compound eye photoreceptor cell differentiation GO:0001751 140 0.036
secretion by cell GO:0032940 101 0.036
cellular chemical homeostasis GO:0055082 40 0.035
endomembrane system organization GO:0010256 119 0.035
carbohydrate metabolic process GO:0005975 82 0.032
central nervous system development GO:0007417 201 0.031
establishment of localization in cell GO:0051649 402 0.031
actomyosin structure organization GO:0031032 56 0.030
intracellular signal transduction GO:0035556 300 0.030
positive regulation of biosynthetic process GO:0009891 316 0.030
regulation of meiosis GO:0040020 3 0.029
respiratory system development GO:0060541 213 0.028
regulation of cell cycle GO:0051726 291 0.028
death GO:0016265 284 0.028
photoreceptor cell differentiation GO:0046530 170 0.028
single organism carbohydrate metabolic process GO:0044723 72 0.027
growth GO:0040007 359 0.027
spindle assembly involved in mitosis GO:0090307 50 0.027
single organism intracellular transport GO:1902582 207 0.027
regulation of transport GO:0051049 181 0.026
response to external biotic stimulus GO:0043207 293 0.026
small gtpase mediated signal transduction GO:0007264 88 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
negative regulation of neurogenesis GO:0050768 53 0.024
oxoacid metabolic process GO:0043436 103 0.024
golgi organization GO:0007030 66 0.023
defense response GO:0006952 300 0.023
glial cell migration GO:0008347 31 0.023
neuron recognition GO:0008038 101 0.023
regulation of secretion GO:0051046 44 0.023
neurological system process GO:0050877 358 0.023
glial cell proliferation GO:0014009 13 0.022
meiotic nuclear division GO:0007126 151 0.022
cellular protein modification process GO:0006464 438 0.022
negative regulation of gene expression GO:0010629 387 0.021
apoptotic process GO:0006915 159 0.021
stem cell development GO:0048864 79 0.021
single organism biosynthetic process GO:0044711 206 0.021
regulation of organelle organization GO:0033043 196 0.021
sensory organ morphogenesis GO:0090596 260 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
Yeast
regulation of neuron differentiation GO:0045664 103 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
cellular ketone metabolic process GO:0042180 24 0.020
cytoplasmic transport GO:0016482 130 0.019
guanosine containing compound catabolic process GO:1901069 74 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
salivary gland morphogenesis GO:0007435 145 0.019
brain development GO:0007420 120 0.019
compound eye photoreceptor development GO:0042051 78 0.019
ion homeostasis GO:0050801 55 0.019
mesenchymal cell differentiation GO:0048762 1 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
neural precursor cell proliferation GO:0061351 75 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
cell migration GO:0016477 238 0.017
cytoplasmic translation GO:0002181 0 0.017
chemical homeostasis GO:0048878 92 0.017
developmental pigmentation GO:0048066 68 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
cell motility GO:0048870 251 0.017
cell cycle phase transition GO:0044770 140 0.017
regulation of heart morphogenesis GO:2000826 3 0.016
purine containing compound catabolic process GO:0072523 112 0.016
Yeast
carboxylic acid metabolic process GO:0019752 92 0.016
response to abiotic stimulus GO:0009628 341 0.016
gene silencing GO:0016458 138 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
Yeast
purine ribonucleoside catabolic process GO:0046130 112 0.015
Yeast
positive regulation of protein metabolic process GO:0051247 128 0.015
eye photoreceptor cell development GO:0042462 81 0.015
maintenance of location GO:0051235 73 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
actin cytoskeleton organization GO:0030036 206 0.015
protein complex biogenesis GO:0070271 201 0.015
protein complex assembly GO:0006461 200 0.015
cell growth GO:0016049 108 0.015
ncrna processing GO:0034470 30 0.015
Yeast
spindle assembly GO:0051225 80 0.015
rna processing GO:0006396 147 0.015
Yeast
regulation of response to stress GO:0080134 200 0.015
reproductive structure development GO:0048608 74 0.015
neuron projection extension GO:1990138 32 0.014
rna splicing via transesterification reactions GO:0000375 73 0.014
centrosome cycle GO:0007098 137 0.014
olfactory behavior GO:0042048 97 0.014
dna integrity checkpoint GO:0031570 81 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
positive regulation of transport GO:0051050 92 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
regulation of mapk cascade GO:0043408 92 0.014
forebrain development GO:0030900 2 0.014
telencephalon development GO:0021537 2 0.014
eye morphogenesis GO:0048592 260 0.014
organelle assembly GO:0070925 198 0.014
catabolic process GO:0009056 409 0.013
Yeast
microtubule organizing center organization GO:0031023 168 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
covalent chromatin modification GO:0016569 106 0.013
cranial nerve development GO:0021545 1 0.013
dna replication GO:0006260 48 0.013
regulation of nucleobase containing compound transport GO:0032239 4 0.012
chromatin assembly GO:0031497 48 0.012
protein dna complex subunit organization GO:0071824 86 0.012
genitalia development GO:0048806 26 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of system process GO:0044057 36 0.012
spermatid nucleus elongation GO:0007290 4 0.012
ribonucleoprotein complex biogenesis GO:0022613 31 0.012
Yeast
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
dna metabolic process GO:0006259 227 0.012
Yeast
circadian rhythm GO:0007623 105 0.012
hair cell differentiation GO:0035315 47 0.012
meiotic cell cycle process GO:1903046 132 0.012
locomotor rhythm GO:0045475 56 0.011
positive regulation of gliogenesis GO:0014015 5 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
single organism catabolic process GO:0044712 228 0.011
Yeast
regulation of developmental growth GO:0048638 174 0.011
mating behavior GO:0007617 106 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
energy taxis GO:0009453 21 0.011
action potential GO:0001508 13 0.011
cellular cation homeostasis GO:0030003 38 0.011
regulation of dendrite development GO:0050773 37 0.011
regulation of cell development GO:0060284 215 0.011
compound eye morphogenesis GO:0001745 249 0.011
response to oxygen containing compound GO:1901700 200 0.011
cellular ion homeostasis GO:0006873 39 0.011
cell fate determination GO:0001709 91 0.011
positive regulation of glial cell proliferation GO:0060252 5 0.010
open tracheal system development GO:0007424 204 0.010
programmed cell death GO:0012501 257 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
cellular homeostasis GO:0019725 80 0.010
organophosphate metabolic process GO:0019637 195 0.010
Yeast
organonitrogen compound catabolic process GO:1901565 128 0.010
Yeast
regulation of cellular response to stress GO:0080135 89 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
determination of dorsal ventral asymmetry GO:0048262 3 0.010
dephosphorylation GO:0016311 51 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
negative regulation of homeostatic process GO:0032845 2 0.010

Hlc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023