Drosophila melanogaster

50 known processes

sbr (Dmel_CG1664)

small bristles

(Aliases: NXF1-p15,CG17335,l(1)9Fd,NXF1,DmNXF1,sbt,dTap,Dmel\CG1664,l(1)G1,l(1)ts403,l(1)ts,CT4634,CG1664,DNXF-1,PABPr,nxf1)

sbr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 200 0.754
sperm individualization GO:0007291 48 0.676
protein modification process GO:0036211 438 0.666
female germ line cyst formation GO:0048135 42 0.608
response to biotic stimulus GO:0009607 294 0.558
single organism behavior GO:0044708 391 0.496
germarium derived female germ line cyst formation GO:0030727 42 0.442
neuron remodeling GO:0016322 29 0.417
cell proliferation GO:0008283 299 0.395
learning or memory GO:0007611 141 0.368
germarium derived egg chamber formation GO:0007293 101 0.354
cellular macromolecule localization GO:0070727 220 0.328
immune system process GO:0002376 347 0.324
lateral inhibition GO:0046331 206 0.323
associative learning GO:0008306 65 0.316
cellular protein modification process GO:0006464 438 0.315
regionalization GO:0003002 416 0.256
oocyte development GO:0048599 124 0.254
negative regulation of signaling GO:0023057 219 0.228
vesicle mediated transport GO:0016192 381 0.228
chemosensory behavior GO:0007635 106 0.224
olfactory behavior GO:0042048 97 0.217
olfactory learning GO:0008355 56 0.213
regulation of cell morphogenesis GO:0022604 163 0.202
neurological system process GO:0050877 358 0.195
oocyte microtubule cytoskeleton organization GO:0016325 35 0.181
response to organic substance GO:0010033 284 0.161
cell death GO:0008219 279 0.156
male gamete generation GO:0048232 201 0.152
photoreceptor cell axon guidance GO:0072499 23 0.152
regulation of behavior GO:0050795 75 0.142
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.121
cell recognition GO:0008037 102 0.116
learning GO:0007612 75 0.115
cognition GO:0050890 141 0.109
mitotic dna damage checkpoint GO:0044773 74 0.108
regulation of cellular component biogenesis GO:0044087 201 0.103
regulation of cell differentiation GO:0045595 302 0.100
single organism cellular localization GO:1902580 180 0.100
response to abiotic stimulus GO:0009628 341 0.097
actin filament organization GO:0007015 126 0.092
regulation of wnt signaling pathway GO:0030111 68 0.090
meiotic nuclear division GO:0007126 151 0.089
regulation of nervous system development GO:0051960 248 0.088
negative regulation of response to stimulus GO:0048585 258 0.085
establishment of localization in cell GO:0051649 402 0.082
long term memory GO:0007616 62 0.079
regulation of protein metabolic process GO:0051246 256 0.074
positive regulation of cellular component organization GO:0051130 156 0.073
regulation of cell development GO:0060284 215 0.070
cellularization GO:0007349 90 0.064
nuclear transport GO:0051169 72 0.063
cellular response to chemical stimulus GO:0070887 199 0.059
negative regulation of signal transduction GO:0009968 206 0.059
response to external biotic stimulus GO:0043207 293 0.058
organic substance catabolic process GO:1901575 308 0.058
negative regulation of cell communication GO:0010648 223 0.055
regulation of growth GO:0040008 233 0.055
cell migration GO:0016477 238 0.054
negative regulation of cellular metabolic process GO:0031324 382 0.053
regulation of cell proliferation GO:0042127 163 0.053
oocyte maturation GO:0001556 3 0.053
negative regulation of gene expression epigenetic GO:0045814 77 0.052
regulation of localization GO:0032879 275 0.052
germ line cyst formation GO:0048134 44 0.051
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.050
negative regulation of immune system process GO:0002683 50 0.050
cell cell signaling involved in cell fate commitment GO:0045168 210 0.049
glial cell migration GO:0008347 31 0.049
protein modification by small protein conjugation GO:0032446 79 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
protein modification by small protein conjugation or removal GO:0070647 106 0.047
actin cytoskeleton organization GO:0030036 206 0.047
response to oxygen containing compound GO:1901700 200 0.047
mitochondrion organization GO:0007005 65 0.046
spermatid differentiation GO:0048515 114 0.046
negative regulation of cell differentiation GO:0045596 143 0.045
rna localization GO:0006403 115 0.044
appendage morphogenesis GO:0035107 397 0.042
blastoderm segmentation GO:0007350 159 0.042
cation transport GO:0006812 110 0.041
reproductive structure development GO:0048608 74 0.041
nucleus localization GO:0051647 34 0.040
cellular amino acid metabolic process GO:0006520 61 0.040
regulation of catalytic activity GO:0050790 185 0.038
pole plasm mrna localization GO:0019094 49 0.038
response to oxygen levels GO:0070482 59 0.038
cell maturation GO:0048469 144 0.037
segmentation GO:0035282 207 0.037
gland development GO:0048732 191 0.037
proteolysis GO:0006508 192 0.037
imaginal disc derived wing vein specification GO:0007474 48 0.037
extrinsic apoptotic signaling pathway GO:0097191 1 0.037
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.037
pole plasm rna localization GO:0007316 52 0.036
protein secretion GO:0009306 45 0.036
oocyte differentiation GO:0009994 145 0.034
response to other organism GO:0051707 293 0.034
memory GO:0007613 94 0.034
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.033
exocrine system development GO:0035272 162 0.033
embryonic axis specification GO:0000578 107 0.033
regulation of immune system process GO:0002682 176 0.032
salivary gland development GO:0007431 162 0.031
mrna processing GO:0006397 104 0.031
regulation of molecular function GO:0065009 217 0.030
autophagic cell death GO:0048102 83 0.029
cellular protein localization GO:0034613 160 0.029
pole plasm oskar mrna localization GO:0045451 46 0.029
development of primary sexual characteristics GO:0045137 50 0.029
sleep GO:0030431 49 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
regulation of kinase activity GO:0043549 53 0.028
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.028
oocyte anterior posterior axis specification GO:0007314 72 0.027
regulation of cellular amine metabolic process GO:0033238 3 0.027
determination of adult lifespan GO:0008340 137 0.027
catabolic process GO:0009056 409 0.027
apoptotic process GO:0006915 159 0.026
immune effector process GO:0002252 98 0.026
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
death GO:0016265 284 0.025
protein localization GO:0008104 284 0.024
cellular response to insulin stimulus GO:0032869 28 0.024
spermatid development GO:0007286 98 0.024
ovarian follicle cell stalk formation GO:0030713 17 0.024
macromolecule catabolic process GO:0009057 161 0.024
chromosome organization GO:0051276 360 0.023
regulation of anatomical structure morphogenesis GO:0022603 242 0.023
mapk cascade GO:0000165 107 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
programmed cell death GO:0012501 257 0.023
fertilization GO:0009566 26 0.023
negative regulation of erbb signaling pathway GO:1901185 29 0.023
camera type eye morphogenesis GO:0048593 2 0.022
response to temperature stimulus GO:0009266 106 0.022
amine metabolic process GO:0009308 12 0.022
tripartite regional subdivision GO:0007351 103 0.022
regulation of multi organism process GO:0043900 131 0.022
regulation of immune response GO:0050776 118 0.022
phosphorylation GO:0016310 294 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
gonad development GO:0008406 50 0.022
organonitrogen compound catabolic process GO:1901565 128 0.022
male meiosis GO:0007140 52 0.022
negative regulation of phosphate metabolic process GO:0045936 45 0.022
regulation of notch signaling pathway GO:0008593 100 0.021
small molecule metabolic process GO:0044281 305 0.021
r7 cell fate commitment GO:0007465 12 0.021
salivary gland morphogenesis GO:0007435 145 0.021
ion transport GO:0006811 145 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
cell cycle phase transition GO:0044770 140 0.021
notch signaling pathway GO:0007219 120 0.020
organelle assembly GO:0070925 198 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
regulation of cell substrate adhesion GO:0010810 2 0.019
mrna metabolic process GO:0016071 124 0.019
regulation of hemocyte proliferation GO:0035206 37 0.019
cell motility GO:0048870 251 0.019
defense response to bacterium GO:0042742 178 0.019
dna biosynthetic process GO:0071897 24 0.019
neuron recognition GO:0008038 101 0.018
multicellular organismal aging GO:0010259 140 0.018
nuclear export GO:0051168 24 0.018
regulation of phosphorylation GO:0042325 147 0.018
wnt signaling pathway GO:0016055 98 0.018
negative regulation of nervous system development GO:0051961 92 0.018
regulation of protein modification process GO:0031399 112 0.018
regulation of cell junction assembly GO:1901888 2 0.018
response to hypoxia GO:0001666 53 0.017
regulation of actin polymerization or depolymerization GO:0008064 27 0.017
circadian sleep wake cycle process GO:0022410 24 0.017
regulation of cell cycle GO:0051726 291 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
regulation of catabolic process GO:0009894 170 0.017
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.017
regulation of response to external stimulus GO:0032101 115 0.017
tissue morphogenesis GO:0048729 297 0.016
fatty acid derivative biosynthetic process GO:1901570 1 0.016
organelle localization GO:0051640 148 0.016
appendage development GO:0048736 401 0.016
homeostatic process GO:0042592 199 0.016
localization of cell GO:0051674 257 0.016
regulation of actin filament length GO:0030832 27 0.016
protein acylation GO:0043543 42 0.015
imaginal disc derived female genitalia development GO:0007486 6 0.015
endomembrane system organization GO:0010256 119 0.015
axon midline choice point recognition GO:0016199 26 0.015
protein phosphorylation GO:0006468 169 0.015
signal transduction by phosphorylation GO:0023014 107 0.014
protein complex assembly GO:0006461 200 0.014
neuron maturation GO:0042551 31 0.014
regulation of response to stress GO:0080134 200 0.014
regulation of photoreceptor cell differentiation GO:0046532 34 0.014
neuron projection guidance GO:0097485 241 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
embryonic pattern specification GO:0009880 174 0.014
cellular response to peptide GO:1901653 28 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
endocytosis GO:0006897 310 0.014
cellular protein complex assembly GO:0043623 71 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of viral genome replication GO:0045069 4 0.013
regulation of protein stability GO:0031647 43 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
motor neuron axon guidance GO:0008045 58 0.013
telencephalon development GO:0021537 2 0.013
intracellular mrna localization GO:0008298 66 0.013
response to lipopolysaccharide GO:0032496 4 0.013
positive regulation of gene expression GO:0010628 290 0.013
gland morphogenesis GO:0022612 145 0.013
icosanoid biosynthetic process GO:0046456 1 0.013
locomotory behavior GO:0007626 176 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
response to endogenous stimulus GO:0009719 119 0.012
response to decreased oxygen levels GO:0036293 58 0.012
positive regulation of notch signaling pathway GO:0045747 34 0.012
cation transmembrane transport GO:0098655 88 0.012
protein transport GO:0015031 155 0.012
regulation of system process GO:0044057 36 0.012
single organism biosynthetic process GO:0044711 206 0.012
response to organonitrogen compound GO:0010243 75 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
taxis GO:0042330 304 0.012
defense response GO:0006952 300 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
nucleoside monophosphate catabolic process GO:0009125 39 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
organic substance transport GO:0071702 257 0.011
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.011
regulation of lipid kinase activity GO:0043550 2 0.011
regulation of apoptotic process GO:0042981 130 0.011
germarium derived oocyte fate determination GO:0007294 26 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
visual learning GO:0008542 4 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
epithelial cell differentiation GO:0030855 322 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
positive regulation of transport GO:0051050 92 0.011
circadian behavior GO:0048512 76 0.011
meiotic cell cycle process GO:1903046 132 0.011
response to zinc ion GO:0010043 3 0.011
regulation of actin filament polymerization GO:0030833 25 0.011
rna processing GO:0006396 147 0.011
tissue death GO:0016271 102 0.011
pronuclear migration GO:0035046 4 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
membrane organization GO:0061024 112 0.011
negative regulation of kinase activity GO:0033673 16 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
establishment of protein localization GO:0045184 163 0.010
germ cell migration GO:0008354 43 0.010
protein polymerization GO:0051258 42 0.010
immune system development GO:0002520 57 0.010
organelle fission GO:0048285 340 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
regulation of cellular localization GO:0060341 136 0.010
single organism membrane organization GO:0044802 93 0.010
negative regulation of phosphorylation GO:0042326 35 0.010
dna damage checkpoint GO:0000077 78 0.010
cellular amine metabolic process GO:0044106 12 0.010

sbr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
musculoskeletal system disease DOID:17 0 0.011
cardiovascular system disease DOID:1287 0 0.011
intrinsic cardiomyopathy DOID:0060036 0 0.011
heart disease DOID:114 0 0.011
dilated cardiomyopathy DOID:12930 0 0.011
cardiomyopathy DOID:0050700 0 0.011
myopathy DOID:423 0 0.011
muscle tissue disease DOID:66 0 0.011
muscular disease DOID:0080000 0 0.011