Drosophila melanogaster

46 known processes

grn (Dmel_CG9656)

grain

(Aliases: l(3)84Fa,Dmel\CG9656,dGatac,CG9656-PA,GATAc,Grn,dGATAc,GRAIN,gra,Gata-c,CG9656,dGATA-2,Gata2)

grn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
motor neuron axon guidance GO:0008045 58 0.969
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.906
Human Zebrafish Mouse Worm Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.897
Human Zebrafish Mouse Worm Fly
regionalization GO:0003002 416 0.897
Fly
blastoderm segmentation GO:0007350 159 0.866
Fly
dendrite guidance GO:0070983 21 0.798
negative regulation of transcription dna templated GO:0045892 237 0.713
Human Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.708
Human Zebrafish Mouse Worm Fly
periodic partitioning GO:0007365 29 0.680
positive regulation of macromolecule metabolic process GO:0010604 405 0.680
Human Zebrafish Mouse Worm Fly
positive regulation of rna metabolic process GO:0051254 271 0.669
Human Zebrafish Mouse Worm Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.600
Human Zebrafish Mouse Worm Fly
axon development GO:0061564 297 0.563
transcription from rna polymerase ii promoter GO:0006366 368 0.557
Human Zebrafish Mouse Worm Fly
connective tissue development GO:0061448 3 0.541
Fly
positive regulation of transcription dna templated GO:0045893 266 0.537
Human Zebrafish Mouse Worm Fly
immune effector process GO:0002252 98 0.536
Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.529
Human Zebrafish Mouse Worm Fly
chemotaxis GO:0006935 249 0.499
response to external biotic stimulus GO:0043207 293 0.488
Fly
neuroblast differentiation GO:0014016 29 0.469
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.443
Human Zebrafish Mouse Worm Fly
appendage morphogenesis GO:0035107 397 0.422
regulation of cell differentiation GO:0045595 302 0.413
Human Zebrafish Mouse
positive regulation of biosynthetic process GO:0009891 316 0.409
Human Zebrafish Mouse Worm Fly
stem cell development GO:0048864 79 0.406
Mouse
neurological system process GO:0050877 358 0.404
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.397
Human Mouse Fly
segmentation GO:0035282 207 0.393
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.388
sex differentiation GO:0007548 81 0.372
Human Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.360
Human Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.356
Human Zebrafish Mouse Worm Fly
stem cell differentiation GO:0048863 117 0.350
Mouse Fly
appendage development GO:0048736 401 0.340
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.335
Human Mouse Fly
cell adhesion GO:0007155 136 0.334
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.333
Human Mouse Fly
neuron recognition GO:0008038 101 0.315
dorsal ventral pattern formation GO:0009953 133 0.315
imaginal disc derived appendage development GO:0048737 399 0.306
regulation of multicellular organismal development GO:2000026 414 0.302
Human Zebrafish Mouse
axon guidance GO:0007411 233 0.294
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.293
Human Mouse Fly
developmental growth GO:0048589 280 0.271
Zebrafish Mouse
tube morphogenesis GO:0035239 191 0.261
Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.249
Human Zebrafish Mouse Worm Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.248
Human Mouse Fly
imaginal disc derived wing hair organization GO:0035317 45 0.222
synaptic target recognition GO:0008039 45 0.222
stem cell proliferation GO:0072089 88 0.221
sensory organ morphogenesis GO:0090596 260 0.217
Zebrafish Mouse
negative regulation of response to stimulus GO:0048585 258 0.216
Human Mouse
mesenchymal cell differentiation GO:0048762 1 0.214
neuroblast development GO:0014019 13 0.213
wing disc morphogenesis GO:0007472 344 0.209
neuron projection guidance GO:0097485 241 0.206
larval development GO:0002164 104 0.202
Fly
body morphogenesis GO:0010171 2 0.196
Worm
organic substance transport GO:0071702 257 0.195
Mouse
positive regulation of gene expression GO:0010628 290 0.189
Human Zebrafish Mouse Worm Fly
response to wounding GO:0009611 94 0.188
Human Zebrafish Mouse
response to biotic stimulus GO:0009607 294 0.186
Fly
regulation of response to stress GO:0080134 200 0.180
regulation of system process GO:0044057 36 0.177
organonitrogen compound biosynthetic process GO:1901566 117 0.176
Mouse Fly
epidermis development GO:0008544 65 0.176
Worm
immune response regulating signaling pathway GO:0002764 2 0.173
Mouse
reproductive system development GO:0061458 74 0.172
Human Mouse
imaginal disc pattern formation GO:0007447 91 0.167
response to other organism GO:0051707 293 0.165
Fly
defense response to other organism GO:0098542 225 0.164
embryo development ending in birth or egg hatching GO:0009792 152 0.162
Zebrafish Mouse Worm Fly
embryonic pattern specification GO:0009880 174 0.157
Fly
epithelial cell differentiation GO:0030855 322 0.152
Mouse Worm
single organism behavior GO:0044708 391 0.152
imaginal disc derived wing morphogenesis GO:0007476 337 0.152
negative regulation of biosynthetic process GO:0009890 277 0.151
Human Mouse Fly
ectodermal placode morphogenesis GO:0071697 4 0.151
Zebrafish
regulation of cell development GO:0060284 215 0.151
Zebrafish Mouse
positive regulation of developmental process GO:0051094 143 0.149
Human Zebrafish Mouse
growth GO:0040007 359 0.147
Zebrafish Mouse
hindgut development GO:0061525 58 0.146
negative regulation of rna metabolic process GO:0051253 251 0.146
Human Mouse Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.144
Zebrafish Mouse
carbohydrate derivative biosynthetic process GO:1901137 85 0.142
Human Mouse
programmed cell death GO:0012501 257 0.141
Human Zebrafish Mouse
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.141
heart development GO:0007507 82 0.140
Zebrafish Mouse Fly
immune response activating signal transduction GO:0002757 2 0.137
Mouse
anterior posterior pattern specification GO:0009952 136 0.136
head development GO:0060322 135 0.136
Mouse
segment polarity determination GO:0007367 25 0.135
cell cell signaling involved in cell fate commitment GO:0045168 210 0.133
tissue morphogenesis GO:0048729 297 0.133
Zebrafish Mouse Fly
positive regulation of cell proliferation GO:0008284 47 0.130
Zebrafish Mouse
terminal region determination GO:0007362 25 0.128
cardiovascular system development GO:0072358 82 0.125
Human Zebrafish Mouse Fly
cell recognition GO:0008037 102 0.124
regulation of immune response GO:0050776 118 0.120
Mouse Fly
synapse assembly GO:0007416 143 0.119
retinal ganglion cell axon guidance GO:0031290 12 0.119
regulation of epithelial cell differentiation GO:0030856 4 0.118
Mouse
memory GO:0007613 94 0.114
gastrulation GO:0007369 70 0.113
Fly
sensory perception of smell GO:0007608 80 0.112
embryonic development via the syncytial blastoderm GO:0001700 148 0.111
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.107
Zebrafish Mouse
reproductive structure development GO:0048608 74 0.105
Human Mouse
central nervous system development GO:0007417 201 0.105
Zebrafish Mouse
response to organic substance GO:0010033 284 0.104
Human Zebrafish Mouse
biological adhesion GO:0022610 138 0.103
Human Mouse
locomotory behavior GO:0007626 176 0.102
regulation of neuron differentiation GO:0045664 103 0.101
Mouse
intracellular signal transduction GO:0035556 300 0.100
Mouse
axis specification GO:0009798 167 0.100
negative regulation of multicellular organismal process GO:0051241 142 0.099
Mouse
activation of innate immune response GO:0002218 4 0.097
dendrite development GO:0016358 204 0.093
regulation of immune effector process GO:0002697 52 0.089
Fly
organonitrogen compound metabolic process GO:1901564 318 0.089
Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.088
detection of stimulus involved in sensory perception GO:0050906 92 0.088
development of primary sexual characteristics GO:0045137 50 0.088
Human Mouse
axonogenesis GO:0007409 290 0.087
positive regulation of cellular protein metabolic process GO:0032270 118 0.086
Human Mouse
neuroblast fate commitment GO:0014017 19 0.085
regulation of protein metabolic process GO:0051246 256 0.083
Human Mouse
limb morphogenesis GO:0035108 1 0.082
secretion by cell GO:0032940 101 0.081
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.080
segment specification GO:0007379 33 0.079
regulation of cellular component biogenesis GO:0044087 201 0.077
skin development GO:0043588 65 0.077
Worm
small molecule metabolic process GO:0044281 305 0.077
heart morphogenesis GO:0003007 32 0.077
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.076
Human Zebrafish Mouse
positive regulation of immune response GO:0050778 63 0.074
Mouse
wound healing GO:0042060 75 0.074
Human Zebrafish Mouse
developmental induction GO:0031128 3 0.073
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.071
dendrite morphogenesis GO:0048813 199 0.069
cardiac cell fate determination GO:0060913 3 0.069
Fly
ventral cord development GO:0007419 16 0.068
wing disc pattern formation GO:0035222 66 0.068
regulation of protein modification process GO:0031399 112 0.067
Human Mouse
tripartite regional subdivision GO:0007351 103 0.066
nephron epithelium development GO:0072009 3 0.066
Mouse
skeletal muscle organ development GO:0060538 48 0.066
peripheral nervous system development GO:0007422 52 0.064
immune response GO:0006955 246 0.064
Mouse Fly
regulation of developmental growth GO:0048638 174 0.064
apoptotic process involved in morphogenesis GO:0060561 3 0.063
synaptic growth at neuromuscular junction GO:0051124 119 0.063
cell proliferation GO:0008283 299 0.063
Human Zebrafish Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.063
cell maturation GO:0048469 144 0.063
Mouse
regulation of embryonic development GO:0045995 68 0.062
Mouse
positive regulation of response to stimulus GO:0048584 323 0.062
Mouse
adult behavior GO:0030534 137 0.060
glial cell differentiation GO:0010001 35 0.060
secretion GO:0046903 109 0.059
Mouse
gliogenesis GO:0042063 80 0.059
taxis GO:0042330 304 0.059
embryonic axis specification GO:0000578 107 0.059
carboxylic acid metabolic process GO:0019752 92 0.058
cellular ketone metabolic process GO:0042180 24 0.058
regulation of humoral immune response GO:0002920 51 0.058
Fly
mesenchymal cell development GO:0014031 1 0.058
dorsal ventral axis specification GO:0009950 66 0.058
nitrogen compound transport GO:0071705 85 0.057
negative regulation of growth GO:0045926 84 0.057
positive regulation of cellular component organization GO:0051130 156 0.057
non sensory hair organization GO:0035316 47 0.056
regulation of response to biotic stimulus GO:0002831 63 0.055
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.055
Human Mouse Fly
maintenance of gastrointestinal epithelium GO:0030277 3 0.054
imaginal disc derived leg morphogenesis GO:0007480 80 0.054
digestive system development GO:0055123 149 0.053
Fly
neural precursor cell proliferation GO:0061351 75 0.051
Human Mouse
regulation of cell proliferation GO:0042127 163 0.051
Human Zebrafish Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.051
Human Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.051
Human Mouse Fly
muscle structure development GO:0061061 224 0.050
negative regulation of neurogenesis GO:0050768 53 0.050
regulation of growth GO:0040008 233 0.049
spiracle morphogenesis open tracheal system GO:0035277 22 0.049
single organism biosynthetic process GO:0044711 206 0.049
positive regulation of cell development GO:0010720 61 0.049
Zebrafish
negative regulation of signaling GO:0023057 219 0.049
Human Mouse
forebrain development GO:0030900 2 0.048
Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.048
endocytosis GO:0006897 310 0.048
Fly
positive regulation of neurogenesis GO:0050769 41 0.047
Zebrafish
negative regulation of synapse assembly GO:0051964 39 0.047
organic substance catabolic process GO:1901575 308 0.047
negative regulation of gene expression GO:0010629 387 0.047
Human Zebrafish Mouse Fly
regulation of neurogenesis GO:0050767 158 0.046
Zebrafish Mouse
antimicrobial peptide production GO:0002775 46 0.046
Fly
cellular protein modification process GO:0006464 438 0.046
Human Mouse
hair cell differentiation GO:0035315 47 0.046
cardiac cell fate commitment GO:0060911 17 0.046
Fly
hemocyte differentiation GO:0042386 38 0.046
Fly
ectodermal placode development GO:0071696 4 0.046
Zebrafish
regulation of defense response GO:0031347 102 0.045
cellular amino acid metabolic process GO:0006520 61 0.045
negative regulation of developmental growth GO:0048640 64 0.045
myoblast proliferation GO:0051450 3 0.045
telencephalon development GO:0021537 2 0.045
outflow tract morphogenesis GO:0003151 4 0.044
female sex differentiation GO:0046660 20 0.044
positive regulation of cell differentiation GO:0045597 64 0.043
Human Zebrafish Mouse
positive regulation of protein metabolic process GO:0051247 128 0.043
Human Mouse
camera type eye development GO:0043010 4 0.042
Mouse
muscle tissue morphogenesis GO:0060415 2 0.042
digestive tract morphogenesis GO:0048546 127 0.042
Fly
cardioblast cell fate determination GO:0007510 3 0.041
Fly
gland development GO:0048732 191 0.041
Mouse Fly
limb development GO:0060173 1 0.041
cell division GO:0051301 248 0.040
covalent chromatin modification GO:0016569 106 0.040
Mouse
negative regulation of cell death GO:0060548 81 0.040
Human Zebrafish Mouse
cellular amine metabolic process GO:0044106 12 0.040
response to bacterium GO:0009617 198 0.039
hindgut morphogenesis GO:0007442 58 0.039
regulation of cell cycle GO:0051726 291 0.039
Mouse
establishment of protein localization GO:0045184 163 0.039
Mouse
regulation of nervous system development GO:0051960 248 0.039
Zebrafish Mouse
retina development in camera type eye GO:0060041 4 0.039
neuroblast fate determination GO:0007400 12 0.039
regulation of intracellular signal transduction GO:1902531 236 0.038
anterior posterior axis specification embryo GO:0008595 103 0.038
camera type eye morphogenesis GO:0048593 2 0.038
protein modification process GO:0036211 438 0.038
Human Mouse
circulatory system development GO:0072359 82 0.038
Human Zebrafish Mouse Fly
synaptic transmission GO:0007268 288 0.038
determination of dorsal ventral asymmetry GO:0048262 3 0.038
response to nitrogen compound GO:1901698 90 0.037
negative regulation of cell communication GO:0010648 223 0.037
Human Mouse
regulation of dendrite development GO:0050773 37 0.037
organic acid metabolic process GO:0006082 103 0.037
positive regulation of signal transduction GO:0009967 223 0.036
axon choice point recognition GO:0016198 26 0.036
response to extracellular stimulus GO:0009991 116 0.036
respiratory system development GO:0060541 213 0.035
regulation of synapse structure and activity GO:0050803 128 0.035
localization of cell GO:0051674 257 0.035
Zebrafish Mouse Fly
protein transport GO:0015031 155 0.035
Mouse
cell death GO:0008219 279 0.035
Human Zebrafish Mouse
regulation of innate immune response GO:0045088 71 0.034
multi organism reproductive behavior GO:0044705 121 0.034
Worm
brain development GO:0007420 120 0.034
Mouse
proximal distal pattern formation GO:0009954 15 0.034
neuron fate commitment GO:0048663 50 0.033
Mouse
kidney epithelium development GO:0072073 3 0.033
Mouse
positive regulation of cell communication GO:0010647 250 0.033
chromatin organization GO:0006325 207 0.033
Mouse
muscle organ development GO:0007517 127 0.032
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.032
heart contraction GO:0060047 26 0.031
Fly
wnt signaling pathway GO:0016055 98 0.031
Mouse
phagocytosis GO:0006909 215 0.031
Fly
anterior posterior axis specification GO:0009948 109 0.031
positive regulation of intracellular signal transduction GO:1902533 116 0.031
determination of adult lifespan GO:0008340 137 0.031
regulation of cell cycle process GO:0010564 181 0.031
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.031
instar larval development GO:0002168 55 0.031
positive regulation of phosphorylation GO:0042327 87 0.030
Human Mouse
positive regulation of cell cycle GO:0045787 43 0.030
regulation of axon extension involved in axon guidance GO:0048841 4 0.030
actin filament organization GO:0007015 126 0.030
positive regulation of secretion GO:0051047 22 0.030
digestive tract development GO:0048565 149 0.030
Fly
formation of anatomical boundary GO:0048859 37 0.029
morphogenesis of a polarized epithelium GO:0001738 93 0.029
axon midline choice point recognition GO:0016199 26 0.029
negative chemotaxis GO:0050919 15 0.029
negative regulation of nervous system development GO:0051961 92 0.029
negative regulation of cell differentiation GO:0045596 143 0.029
Human Mouse
chromatin remodeling GO:0006338 72 0.029
mesenchyme development GO:0060485 9 0.029
cell motility GO:0048870 251 0.029
Zebrafish Mouse Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.029
establishment of tissue polarity GO:0007164 87 0.028
pharynx development GO:0060465 1 0.028
eye development GO:0001654 323 0.028
Mouse
regulation of immune system process GO:0002682 176 0.027
Human Zebrafish Mouse Fly
olfactory bulb axon guidance GO:0071678 3 0.027
pigment cell differentiation GO:0050931 3 0.027
response to mechanical stimulus GO:0009612 28 0.027
regulation of molecular function GO:0065009 217 0.027
Human Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
Human Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.026
Human Mouse
innate immune response GO:0045087 144 0.026
pattern recognition receptor signaling pathway GO:0002221 2 0.026
positive regulation of signaling GO:0023056 243 0.026
regulation of response to external stimulus GO:0032101 115 0.026
Fly
amine metabolic process GO:0009308 12 0.026
sensory perception of chemical stimulus GO:0007606 116 0.026
cell cell adhesion GO:0098609 26 0.026
cellular response to chemical stimulus GO:0070887 199 0.026
Human Zebrafish Mouse
leg disc development GO:0035218 92 0.026
regulation of cellular component size GO:0032535 98 0.025
kidney development GO:0001822 3 0.025
Mouse
dorsal ventral axon guidance GO:0033563 2 0.025
ameboidal type cell migration GO:0001667 151 0.025
defense response to bacterium GO:0042742 178 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
nephron tubule morphogenesis GO:0072078 3 0.025
Mouse
tube formation GO:0035148 21 0.025
Mouse
regulation of response to wounding GO:1903034 19 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
Human Mouse
regulation of neuron projection development GO:0010975 69 0.025
Mouse
sleep GO:0030431 49 0.024
actin cytoskeleton organization GO:0030036 206 0.024
ectodermal placode formation GO:0060788 4 0.024
Zebrafish
renal system development GO:0072001 72 0.024
Mouse Fly
negative regulation of cell development GO:0010721 62 0.024
central nervous system projection neuron axonogenesis GO:0021952 6 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
detection of chemical stimulus GO:0009593 93 0.024
oxoacid metabolic process GO:0043436 103 0.024
torso signaling pathway GO:0008293 21 0.024
regulation of multicellular organism growth GO:0040014 40 0.024
developmental programmed cell death GO:0010623 138 0.023
organophosphate metabolic process GO:0019637 195 0.023
neuroblast proliferation GO:0007405 74 0.023
spinal cord development GO:0021510 1 0.023
Zebrafish Mouse
extrinsic apoptotic signaling pathway GO:0097191 1 0.023
Human
response to oxygen containing compound GO:1901700 200 0.023
genitalia development GO:0048806 26 0.023
chaeta development GO:0022416 97 0.023
Fly
regulation of embryonic pattern specification GO:1902875 27 0.023
determination of ventral identity GO:0048264 1 0.023
catabolic process GO:0009056 409 0.023
Fly
innate immune response activating signal transduction GO:0002758 2 0.023
nephron tubule formation GO:0072079 3 0.022
Mouse
anterior commissure morphogenesis GO:0021960 2 0.022
developmental maturation GO:0021700 172 0.022
Mouse
nephron morphogenesis GO:0072028 3 0.022
Mouse
wing disc dorsal ventral pattern formation GO:0048190 47 0.022
imaginal disc derived leg segmentation GO:0036011 26 0.022
response to endogenous stimulus GO:0009719 119 0.022
Human Zebrafish Mouse
renal tubule development GO:0061326 64 0.021
Mouse
positive regulation of nervous system development GO:0051962 69 0.021
Zebrafish
glial cell development GO:0021782 27 0.021
histone modification GO:0016570 106 0.021
Mouse
female gonad development GO:0008585 12 0.021
death GO:0016265 284 0.021
Human Zebrafish Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.021
establishment of planar polarity GO:0001736 87 0.021
specification of segmental identity head GO:0007380 11 0.021
response to acid chemical GO:0001101 25 0.020
gland morphogenesis GO:0022612 145 0.020
Fly
actin filament based process GO:0030029 220 0.020
nephron epithelium morphogenesis GO:0072088 3 0.020
Mouse
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.020
cell type specific apoptotic process GO:0097285 38 0.020
Mouse
regulation of cell projection organization GO:0031344 92 0.020
Mouse
feeding behavior GO:0007631 50 0.019
phosphorylation GO:0016310 294 0.019
Human Mouse
eye morphogenesis GO:0048592 260 0.019
regulation of membrane potential GO:0042391 35 0.019
molting cycle GO:0042303 56 0.019
regulation of cellular localization GO:0060341 136 0.019
endocrine system development GO:0035270 5 0.019
Mouse
epidermal cell differentiation GO:0009913 51 0.019
Worm
regulation of wnt signaling pathway GO:0030111 68 0.019
compound eye retinal cell programmed cell death GO:0046667 23 0.019
retina morphogenesis in camera type eye GO:0060042 2 0.019
cell migration GO:0016477 238 0.018
Zebrafish Mouse Fly
negative regulation of protein metabolic process GO:0051248 85 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
Human Mouse
carbohydrate metabolic process GO:0005975 82 0.018
development of primary female sexual characteristics GO:0046545 12 0.018
nephron tubule development GO:0072080 3 0.018
Mouse
regulation of multi organism process GO:0043900 131 0.018
Fly
trunk segmentation GO:0035290 8 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.018
renal tubule morphogenesis GO:0061333 44 0.018
Mouse
negative regulation of developmental process GO:0051093 201 0.018
Human Mouse
kidney morphogenesis GO:0060993 3 0.017
Mouse
synapse organization GO:0050808 196 0.017
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.017
peptide metabolic process GO:0006518 80 0.017
Fly
regulation of cell division GO:0051302 72 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
Human Zebrafish Mouse
multicellular organism growth GO:0035264 46 0.017
positive regulation of axonogenesis GO:0050772 2 0.017
positive regulation of innate immune response GO:0045089 38 0.017
negative regulation of signal transduction GO:0009968 206 0.017
Human Mouse
stem cell division GO:0017145 69 0.017
defense response to fungus GO:0050832 48 0.017
regulation of antimicrobial humoral response GO:0002759 50 0.017
Fly
regulation of behavior GO:0050795 75 0.017
regulation of photoreceptor cell axon guidance GO:2000289 5 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
compound eye development GO:0048749 307 0.017
embryonic foregut morphogenesis GO:0048617 3 0.016
compound eye morphogenesis GO:0001745 249 0.016
regulation of circadian rhythm GO:0042752 49 0.016
anterior head development GO:0097065 3 0.016
establishment of localization in cell GO:0051649 402 0.016
Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
intracellular mrna localization GO:0008298 66 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
long term memory GO:0007616 62 0.016
leg disc morphogenesis GO:0007478 80 0.016
chromatin modification GO:0016568 147 0.016
Mouse
single organism catabolic process GO:0044712 228 0.016
regulation of localization GO:0032879 275 0.016
Zebrafish
urogenital system development GO:0001655 72 0.016
Mouse Fly
regulation of stem cell proliferation GO:0072091 40 0.016
regulation of antimicrobial peptide production GO:0002784 44 0.016
Fly
defense response GO:0006952 300 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
Human Zebrafish Mouse
cellular response to organic substance GO:0071310 132 0.015
Human Zebrafish Mouse
positive regulation of defense response GO:0031349 59 0.015
striated muscle tissue development GO:0014706 27 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
appendage segmentation GO:0035285 26 0.015
protein import GO:0017038 55 0.015
regulation of synapse assembly GO:0051963 94 0.015
chromosome organization GO:0051276 360 0.015
Mouse
positive regulation of neuron differentiation GO:0045666 26 0.015
regulation of cell size GO:0008361 63 0.015
antimicrobial humoral response GO:0019730 99 0.015
Fly
muscle tissue development GO:0060537 30 0.015
aging GO:0007568 143 0.015
maintenance of location GO:0051235 73 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
salivary gland morphogenesis GO:0007435 145 0.015
Fly
central nervous system segmentation GO:0035283 5 0.015
neuron death GO:0070997 27 0.014
Mouse
cell growth GO:0016049 108 0.014
post embryonic hemopoiesis GO:0035166 17 0.014
Fly
positive regulation of axon extension GO:0045773 2 0.014
mesoderm development GO:0007498 78 0.014
Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
Human Mouse
somatic muscle development GO:0007525 66 0.014
amide biosynthetic process GO:0043604 42 0.014
Fly
regulation of reproductive process GO:2000241 54 0.014
pigmentation GO:0043473 75 0.014
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.014
oocyte construction GO:0007308 112 0.014
axonal defasciculation GO:0007414 12 0.014
positive regulation of developmental growth GO:0048639 62 0.014
neuron fate specification GO:0048665 12 0.014
energy derivation by oxidation of organic compounds GO:0015980 32 0.014
protein acetylation GO:0006473 39 0.014
Mouse
skeletal muscle tissue development GO:0007519 13 0.014
positive regulation of growth GO:0045927 75 0.014
positive regulation of cell cycle process GO:0090068 28 0.013
adult locomotory behavior GO:0008344 76 0.013
male gamete generation GO:0048232 201 0.013
Worm
homeostatic process GO:0042592 199 0.013
Human Zebrafish Mouse Fly
thermotaxis GO:0043052 16 0.013
spermatid differentiation GO:0048515 114 0.013
positive regulation of response to biotic stimulus GO:0002833 31 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
open tracheal system development GO:0007424 204 0.013
larval lymph gland hemopoiesis GO:0035167 17 0.013
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.013
neuron maturation GO:0042551 31 0.013
central nervous system neuron differentiation GO:0021953 8 0.013
Zebrafish Mouse
imaginal disc derived wing vein specification GO:0007474 48 0.013
olfactory learning GO:0008355 56 0.013
malpighian tubule development GO:0072002 64 0.013
regulation of hemocyte differentiation GO:0045610 22 0.013
regulation of secretion GO:0051046 44 0.013
head segmentation GO:0035287 13 0.013
cellular amide metabolic process GO:0043603 80 0.013
Fly
positive regulation of neuron projection development GO:0010976 14 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.012
bmp signaling pathway GO:0030509 27 0.012
jak stat cascade GO:0007259 49 0.012
regulation of programmed cell death GO:0043067 152 0.012
Human Zebrafish Mouse

grn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
Human
musculoskeletal system disease DOID:17 0 0.052
cancer DOID:162 0 0.038
Human
disease of cellular proliferation DOID:14566 0 0.038
Human
congenital heart disease DOID:1682 0 0.030
heart disease DOID:114 0 0.030
cardiovascular system disease DOID:1287 0 0.030
organ system cancer DOID:0050686 0 0.021
Human
nervous system disease DOID:863 0 0.021
bone development disease DOID:0080006 0 0.018
bone disease DOID:0080001 0 0.018
connective tissue disease DOID:65 0 0.018
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
tetralogy of fallot DOID:6419 0 0.015
artery disease DOID:0050828 0 0.015
vascular disease DOID:178 0 0.015