Drosophila melanogaster

141 known processes

brk (Dmel_CG9653)

brinker

(Aliases: Dmel\CG9653,Brk,CG9653,ssg-1)

brk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube development GO:0035295 244 0.997
negative regulation of rna biosynthetic process GO:1902679 240 0.997
negative regulation of cellular biosynthetic process GO:0031327 277 0.993
negative regulation of transcription dna templated GO:0045892 237 0.989
transcription from rna polymerase ii promoter GO:0006366 368 0.986
tissue morphogenesis GO:0048729 297 0.984
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.950
negative regulation of nucleic acid templated transcription GO:1903507 240 0.946
ovarian follicle cell development GO:0030707 248 0.901
positive regulation of biosynthetic process GO:0009891 316 0.892
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.888
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.880
cell proliferation GO:0008283 299 0.871
response to alcohol GO:0097305 95 0.857
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.856
negative regulation of cell proliferation GO:0008285 69 0.855
negative regulation of rna metabolic process GO:0051253 251 0.851
morphogenesis of an epithelium GO:0002009 276 0.849
stem cell differentiation GO:0048863 117 0.837
columnar cuboidal epithelial cell development GO:0002066 249 0.835
regionalization GO:0003002 416 0.834
Fly
regulation of cell proliferation GO:0042127 163 0.827
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.821
epithelial cell development GO:0002064 274 0.818
regulation of organ morphogenesis GO:2000027 78 0.816
centrosome organization GO:0051297 163 0.811
chorion containing eggshell formation GO:0007304 105 0.793
digestive tract development GO:0048565 149 0.782
stem cell proliferation GO:0072089 88 0.775
negative regulation of gene expression GO:0010629 387 0.760
post embryonic appendage morphogenesis GO:0035120 385 0.751
digestive system development GO:0055123 149 0.748
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.739
dendrite morphogenesis GO:0048813 199 0.733
axon guidance GO:0007411 233 0.709
negative regulation of signaling GO:0023057 219 0.701
positive regulation of nucleic acid templated transcription GO:1903508 266 0.695
dendrite development GO:0016358 204 0.689
morphogenesis of embryonic epithelium GO:0016331 94 0.674
imaginal disc derived appendage development GO:0048737 399 0.660
embryonic morphogenesis GO:0048598 206 0.655
compound eye development GO:0048749 307 0.643
embryonic heart tube development GO:0035050 22 0.616
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.602
dna metabolic process GO:0006259 227 0.596
Fly
central nervous system development GO:0007417 201 0.590
negative regulation of cellular metabolic process GO:0031324 382 0.590
regulation of heart morphogenesis GO:2000826 3 0.589
neuroblast development GO:0014019 13 0.578
salivary gland development GO:0007431 162 0.564
appendage morphogenesis GO:0035107 397 0.557
ameboidal type cell migration GO:0001667 151 0.547
regulation of embryonic development GO:0045995 68 0.543
nephron morphogenesis GO:0072028 3 0.539
eye development GO:0001654 323 0.531
regulation of epithelial cell proliferation GO:0050678 4 0.522
positive regulation of gene expression GO:0010628 290 0.521
segmentation GO:0035282 207 0.517
head involution GO:0008258 35 0.505
regulation of stem cell proliferation GO:0072091 40 0.502
cellular protein modification process GO:0006464 438 0.501
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.497
axon development GO:0061564 297 0.485
dorsal ventral pattern formation GO:0009953 133 0.477
epithelial cell differentiation GO:0030855 322 0.462
cell cell signaling involved in cell fate commitment GO:0045168 210 0.442
tissue migration GO:0090130 155 0.436
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.417
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.417
mesodermal cell fate specification GO:0007501 2 0.415
death GO:0016265 284 0.413
positive regulation of transcription dna templated GO:0045893 266 0.413
stem cell fate commitment GO:0048865 25 0.413
gastrulation GO:0007369 70 0.402
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.397
apoptotic process GO:0006915 159 0.392
negative regulation of signal transduction GO:0009968 206 0.391
oocyte development GO:0048599 124 0.389
positive regulation of cellular biosynthetic process GO:0031328 316 0.382
growth GO:0040007 359 0.373
sensory organ morphogenesis GO:0090596 260 0.371
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.368
embryonic development via the syncytial blastoderm GO:0001700 148 0.364
embryonic pattern specification GO:0009880 174 0.360
alcohol biosynthetic process GO:0046165 14 0.349
stem cell development GO:0048864 79 0.334
compound eye morphogenesis GO:0001745 249 0.334
smoothened signaling pathway GO:0007224 49 0.332
negative regulation of cell differentiation GO:0045596 143 0.320
tube morphogenesis GO:0035239 191 0.318
axis specification GO:0009798 167 0.314
gland development GO:0048732 191 0.314
regulation of cell division GO:0051302 72 0.312
regulation of cell fate commitment GO:0010453 29 0.309
imaginal disc derived appendage morphogenesis GO:0035114 395 0.303
neuron fate commitment GO:0048663 50 0.302
malpighian tubule morphogenesis GO:0007443 44 0.297
kidney morphogenesis GO:0060993 3 0.286
regulation of cell fate specification GO:0042659 27 0.285
negative regulation of response to stimulus GO:0048585 258 0.280
embryonic axis specification GO:0000578 107 0.268
regulation of cell differentiation GO:0045595 302 0.267
blastoderm segmentation GO:0007350 159 0.266
brain development GO:0007420 120 0.266
mating behavior GO:0007617 106 0.261
Fly
imaginal disc pattern formation GO:0007447 91 0.255
regulation of bmp signaling pathway GO:0030510 23 0.253
digestive tract morphogenesis GO:0048546 127 0.252
programmed cell death GO:0012501 257 0.240
eggshell formation GO:0030703 105 0.239
heart development GO:0007507 82 0.238
cell death GO:0008219 279 0.233
r3 r4 cell differentiation GO:0048056 12 0.233
positive regulation of rna biosynthetic process GO:1902680 266 0.230
sex differentiation GO:0007548 81 0.225
regulation of anatomical structure morphogenesis GO:0022603 242 0.224
connective tissue development GO:0061448 3 0.221
cell fate commitment involved in pattern specification GO:0060581 31 0.221
head development GO:0060322 135 0.219
neuron projection guidance GO:0097485 241 0.217
regulation of cell death GO:0010941 173 0.215
neuroblast proliferation GO:0007405 74 0.215
development of primary sexual characteristics GO:0045137 50 0.212
lateral inhibition GO:0046331 206 0.211
nephron tubule morphogenesis GO:0072078 3 0.210
bmp signaling pathway GO:0030509 27 0.206
imaginal disc derived leg morphogenesis GO:0007480 80 0.206
negative regulation of developmental process GO:0051093 201 0.205
Worm
cell division GO:0051301 248 0.199
regulation of cell cycle GO:0051726 291 0.198
negative regulation of cell communication GO:0010648 223 0.198
nephron epithelium development GO:0072009 3 0.195
positive regulation of macromolecule metabolic process GO:0010604 405 0.190
regulation of growth GO:0040008 233 0.189
imaginal disc derived wing vein specification GO:0007474 48 0.189
Fly
regulation of mitosis GO:0007088 56 0.189
establishment of planar polarity GO:0001736 87 0.186
epithelial cell proliferation GO:0050673 15 0.184
exocrine system development GO:0035272 162 0.183
neural retina development GO:0003407 4 0.180
cell migration involved in gastrulation GO:0042074 9 0.175
taxis GO:0042330 304 0.169
leg disc development GO:0035218 92 0.169
mesoderm formation GO:0001707 21 0.168
epithelial cell migration GO:0010631 148 0.167
cellular response to organic cyclic compound GO:0071407 32 0.166
positive regulation of cell proliferation GO:0008284 47 0.166
reproductive structure development GO:0048608 74 0.163
regulation of apoptotic process GO:0042981 130 0.163
positive regulation of apoptotic process GO:0043065 47 0.159
malpighian tubule development GO:0072002 64 0.158
r7 cell differentiation GO:0045466 43 0.157
ventral midline development GO:0007418 9 0.156
photoreceptor cell fate commitment GO:0046552 41 0.155
appendage development GO:0048736 401 0.154
response to sterol GO:0036314 34 0.152
compound eye photoreceptor fate commitment GO:0001752 36 0.152
kidney development GO:0001822 3 0.152
dorsal closure GO:0007391 79 0.150
reproductive system development GO:0061458 74 0.147
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.143
negative regulation of intracellular signal transduction GO:1902532 57 0.140
intracellular signal transduction GO:0035556 300 0.134
mitotic nuclear division GO:0007067 213 0.133
Fly
gland morphogenesis GO:0022612 145 0.132
regulation of multicellular organismal development GO:2000026 414 0.128
Worm
eye photoreceptor cell differentiation GO:0001754 145 0.127
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.125
wing disc morphogenesis GO:0007472 344 0.125
mesoderm development GO:0007498 78 0.123
mesenchymal cell differentiation GO:0048762 1 0.123
regulation of cell development GO:0060284 215 0.120
regulation of neuroblast proliferation GO:1902692 34 0.115
urogenital system development GO:0001655 72 0.115
cell maturation GO:0048469 144 0.114
pharynx development GO:0060465 1 0.112
localization of cell GO:0051674 257 0.111
regulation of programmed cell death GO:0043067 152 0.111
cell fate determination GO:0001709 91 0.111
cell motility GO:0048870 251 0.111
signal transduction downstream of smoothened GO:0007227 5 0.110
neural precursor cell proliferation GO:0061351 75 0.109
phosphorylation GO:0016310 294 0.109
motor neuron axon guidance GO:0008045 58 0.107
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.106
convergent extension GO:0060026 2 0.106
positive regulation of developmental growth GO:0048639 62 0.105
renal tubule development GO:0061326 64 0.105
negative regulation of biosynthetic process GO:0009890 277 0.102
regulation of phosphorus metabolic process GO:0051174 210 0.102
microtubule organizing center organization GO:0031023 168 0.101
eggshell chorion assembly GO:0007306 66 0.100
regulation of epithelial cell differentiation GO:0030856 4 0.099
spinal cord dorsal ventral patterning GO:0021513 1 0.098
cell migration GO:0016477 238 0.093
chromosome organization GO:0051276 360 0.093
Fly
regulation of intracellular signal transduction GO:1902531 236 0.091
lipid metabolic process GO:0006629 121 0.091
r3 r4 cell fate commitment GO:0007464 10 0.090
ion transport GO:0006811 145 0.089
establishment or maintenance of cell polarity GO:0007163 167 0.088
regulation of lipid metabolic process GO:0019216 15 0.086
positive regulation of developmental process GO:0051094 143 0.085
eye antennal disc morphogenesis GO:0007455 34 0.084
negative regulation of phosphorus metabolic process GO:0010563 45 0.084
negative regulation of cell fate specification GO:0009996 15 0.084
negative regulation of cell death GO:0060548 81 0.083
chromatin organization GO:0006325 207 0.083
forebrain development GO:0030900 2 0.083
branching morphogenesis of an epithelial tube GO:0048754 45 0.083
negative regulation of heart induction GO:1901320 3 0.082
regulation of cell cycle process GO:0010564 181 0.082
anterior posterior axis specification GO:0009948 109 0.082
intrinsic apoptotic signaling pathway GO:0097193 16 0.081
regulation of cell morphogenesis GO:0022604 163 0.079
positive regulation of programmed cell death GO:0043068 62 0.079
determination of ventral identity GO:0048264 1 0.078
eye morphogenesis GO:0048592 260 0.078
response to oxygen containing compound GO:1901700 200 0.078
neurological system process GO:0050877 358 0.077
epidermal cell differentiation GO:0009913 51 0.074
hindgut morphogenesis GO:0007442 58 0.074
negative regulation of immune system process GO:0002683 50 0.073
kidney epithelium development GO:0072073 3 0.072
regulation of cellular response to growth factor stimulus GO:0090287 13 0.072
photoreceptor cell differentiation GO:0046530 170 0.072
developmental maturation GO:0021700 172 0.071
developmental programmed cell death GO:0010623 138 0.070
cardiac cell fate commitment GO:0060911 17 0.069
vitamin metabolic process GO:0006766 2 0.068
nephron tubule development GO:0072080 3 0.067
epithelial structure maintenance GO:0010669 17 0.067
eye photoreceptor cell development GO:0042462 81 0.066
protein modification process GO:0036211 438 0.065
regulation of neuron projection development GO:0010975 69 0.064
ovarian follicle cell migration GO:0007297 121 0.064
oocyte differentiation GO:0009994 145 0.063
spindle assembly GO:0051225 80 0.062
establishment of tissue polarity GO:0007164 87 0.062
regulation of stem cell differentiation GO:2000736 14 0.061
circulatory system development GO:0072359 82 0.061
positive regulation of cell death GO:0010942 69 0.060
retina development in camera type eye GO:0060041 4 0.060
response to light stimulus GO:0009416 124 0.058
protein phosphorylation GO:0006468 169 0.058
small molecule metabolic process GO:0044281 305 0.057
meiotic cell cycle GO:0051321 171 0.057
protein catabolic process GO:0030163 101 0.055
neuroblast differentiation GO:0014016 29 0.055
enzyme linked receptor protein signaling pathway GO:0007167 179 0.054
regulation of dendrite morphogenesis GO:0048814 28 0.054
centrosome duplication GO:0051298 121 0.054
cellular component assembly involved in morphogenesis GO:0010927 151 0.054
glial cell fate commitment GO:0021781 3 0.053
compound eye retinal cell programmed cell death GO:0046667 23 0.053
nuclear division GO:0000280 332 0.053
Fly
stem cell maintenance GO:0019827 67 0.053
imaginal disc derived wing morphogenesis GO:0007476 337 0.052
regulation of cardioblast differentiation GO:0051890 9 0.052
regulation of muscle organ development GO:0048634 13 0.052
developmental growth GO:0048589 280 0.052
retina morphogenesis in camera type eye GO:0060042 2 0.051
open tracheal system development GO:0007424 204 0.051
female mating behavior GO:0060180 30 0.051
oocyte axis specification GO:0007309 108 0.051
heart morphogenesis GO:0003007 32 0.050
macromolecule catabolic process GO:0009057 161 0.050
positive regulation of signaling GO:0023056 243 0.049
determination of dorsal ventral asymmetry GO:0048262 3 0.049
regulation of steroid metabolic process GO:0019218 2 0.048
camera type eye development GO:0043010 4 0.048
skin development GO:0043588 65 0.048
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.048
single organism cell adhesion GO:0098602 47 0.047
wing disc dorsal ventral pattern formation GO:0048190 47 0.047
epithelial tube morphogenesis GO:0060562 88 0.046
regulation of phosphorylation GO:0042325 147 0.046
positive regulation of cell communication GO:0010647 250 0.046
negative regulation of wnt signaling pathway GO:0030178 28 0.045
muscle organ development GO:0007517 127 0.045
tripartite regional subdivision GO:0007351 103 0.045
centrosome cycle GO:0007098 137 0.045
wnt signaling pathway GO:0016055 98 0.045
cardiovascular system development GO:0072358 82 0.045
chromatin assembly or disassembly GO:0006333 52 0.044
spinal cord development GO:0021510 1 0.043
organelle fission GO:0048285 340 0.043
Fly
nephron development GO:0072006 3 0.042
cell fate specification involved in pattern specification GO:0060573 8 0.042
compound eye photoreceptor development GO:0042051 78 0.041
cardioblast cell fate commitment GO:0042684 14 0.041
cellular ketone metabolic process GO:0042180 24 0.041
regulation of epidermal cell differentiation GO:0045604 3 0.041
organ formation GO:0048645 39 0.040
regulation of neurogenesis GO:0050767 158 0.040
cell fate specification GO:0001708 71 0.040
positive regulation of histone deacetylation GO:0031065 2 0.040
regulation of ras protein signal transduction GO:0046578 93 0.039
formation of anatomical boundary GO:0048859 37 0.039
response to radiation GO:0009314 155 0.039
positive regulation of protein deacetylation GO:0090312 2 0.039
epithelium migration GO:0090132 148 0.038
regulation of cellular catabolic process GO:0031329 157 0.038
regulation of heart induction GO:0090381 3 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.038
response to biotic stimulus GO:0009607 294 0.038
autophagic cell death GO:0048102 83 0.038
epidermis development GO:0008544 65 0.038
salivary gland cell autophagic cell death GO:0035071 83 0.038
regulation of imaginal disc derived wing size GO:0044719 20 0.038
salivary gland histolysis GO:0035070 88 0.037
single organism cellular localization GO:1902580 180 0.037
neuron fate specification GO:0048665 12 0.037
single organism behavior GO:0044708 391 0.037
protein ubiquitination GO:0016567 70 0.037
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.037
regulation of catalytic activity GO:0050790 185 0.037
regulation of cellular protein metabolic process GO:0032268 243 0.036
axonogenesis GO:0007409 290 0.036
chemotaxis GO:0006935 249 0.036
neuroblast fate commitment GO:0014017 19 0.036
multi organism reproductive behavior GO:0044705 121 0.035
Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.035
proteolysis GO:0006508 192 0.034
anterior posterior axis specification embryo GO:0008595 103 0.034
retinal ganglion cell axon guidance GO:0031290 12 0.034
renal tubule morphogenesis GO:0061333 44 0.033
morphogenesis of an epithelial bud GO:0060572 3 0.033
regulation of protein deacetylation GO:0090311 2 0.033
germ cell migration GO:0008354 43 0.033
negative regulation of phosphate metabolic process GO:0045936 45 0.032
positive regulation of neurogenesis GO:0050769 41 0.032
negative regulation of bmp signaling pathway GO:0030514 12 0.032
cellular response to organic substance GO:0071310 132 0.032
response to mechanical stimulus GO:0009612 28 0.032
specification of segmental identity head GO:0007380 11 0.032
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.032
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.032
protein localization GO:0008104 284 0.031
mesenchymal cell development GO:0014031 1 0.031
negative regulation of epithelial cell proliferation GO:0050680 4 0.031
regulation of organ formation GO:0003156 3 0.031
response to organic cyclic compound GO:0014070 89 0.030
response to organic substance GO:0010033 284 0.030
hemocyte differentiation GO:0042386 38 0.030
locomotory behavior GO:0007626 176 0.029
mesenchyme development GO:0060485 9 0.029
compound eye photoreceptor cell differentiation GO:0001751 140 0.029
salivary gland morphogenesis GO:0007435 145 0.029
cuticle development GO:0042335 86 0.029
regulation of compound eye photoreceptor development GO:0045314 12 0.029
regulation of reproductive process GO:2000241 54 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.028
mating GO:0007618 120 0.028
Fly
positive regulation of signal transduction GO:0009967 223 0.028
glandular epithelial cell differentiation GO:0002067 1 0.028
jak stat cascade GO:0007259 49 0.028
cellular macromolecule localization GO:0070727 220 0.028
ras protein signal transduction GO:0007265 88 0.028
cellular response to extracellular stimulus GO:0031668 64 0.027
developmental induction GO:0031128 3 0.027
negative regulation of smoothened signaling pathway GO:0045879 16 0.027
positive regulation of growth GO:0045927 75 0.027
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.026
mitotic spindle organization GO:0007052 220 0.026
protein targeting GO:0006605 64 0.026
regulation of cellular localization GO:0060341 136 0.026
morphogenesis of a branching epithelium GO:0061138 45 0.026
ribose phosphate metabolic process GO:0019693 145 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
regulation of nuclear division GO:0051783 58 0.025
positive regulation of rna metabolic process GO:0051254 271 0.025
cell projection assembly GO:0030031 94 0.025
chorion containing eggshell pattern formation GO:0030381 11 0.025
cellular response to growth factor stimulus GO:0071363 30 0.025
biological adhesion GO:0022610 138 0.025
protein complex biogenesis GO:0070271 201 0.025
photoreceptor cell fate specification GO:0043704 9 0.024
regulation of molecular function GO:0065009 217 0.024
brain morphogenesis GO:0048854 16 0.024
neuroblast fate determination GO:0007400 12 0.024
regulation of developmental pigmentation GO:0048070 24 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.024
chromatin modification GO:0016568 147 0.024
anterior posterior pattern specification GO:0009952 136 0.024
negative regulation of cardioblast differentiation GO:0051892 7 0.023
embryonic organ development GO:0048568 50 0.023
nephron epithelium morphogenesis GO:0072088 3 0.023
heart induction GO:0003129 3 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.023
eye antennal disc development GO:0035214 60 0.023
cellular response to nutrient levels GO:0031669 62 0.023
wing cell fate specification GO:0035311 3 0.023
telencephalon development GO:0021537 2 0.023
ketone biosynthetic process GO:0042181 16 0.023
negative regulation of multicellular organismal process GO:0051241 142 0.023
Worm
negative regulation of stem cell differentiation GO:2000737 8 0.023
small gtpase mediated signal transduction GO:0007264 88 0.022
response to abiotic stimulus GO:0009628 341 0.022
organic substance transport GO:0071702 257 0.022
multicellular organism growth GO:0035264 46 0.022
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.022
induction of programmed cell death by hormones GO:0035081 12 0.022
negative regulation of nervous system development GO:0051961 92 0.022
cardioblast differentiation GO:0010002 20 0.022
dorsal ventral axis specification GO:0009950 66 0.021
negative regulation of apoptotic process GO:0043066 63 0.021
genitalia development GO:0048806 26 0.021
camera type eye morphogenesis GO:0048593 2 0.021
heart formation GO:0060914 6 0.021
stem cell fate determination GO:0048867 15 0.021
protein complex assembly GO:0006461 200 0.021
limb morphogenesis GO:0035108 1 0.021
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.020
negative regulation of cell fate commitment GO:0010454 17 0.020
stem cell fate specification GO:0048866 2 0.020
purine containing compound metabolic process GO:0072521 155 0.020
regulation of kinase activity GO:0043549 53 0.020
spindle organization GO:0007051 253 0.020
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.019
mushroom body development GO:0016319 70 0.019
negative regulation of cell division GO:0051782 17 0.019
cell type specific apoptotic process GO:0097285 38 0.019
eye photoreceptor cell fate commitment GO:0042706 37 0.019
long term memory GO:0007616 62 0.019
regulation of retinal cell programmed cell death GO:0046668 18 0.018
regulation of proteasomal protein catabolic process GO:0061136 39 0.018
muscle structure development GO:0061061 224 0.018
positive regulation of execution phase of apoptosis GO:1900119 4 0.018
positive regulation of mitotic cell cycle GO:0045931 34 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
steroid biosynthetic process GO:0006694 16 0.017
hindbrain development GO:0030902 2 0.017
developmental pigmentation GO:0048066 68 0.017
organic substance catabolic process GO:1901575 308 0.017
enteroendocrine cell differentiation GO:0035883 1 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
regulation of cellular response to stress GO:0080135 89 0.017
synapse assembly GO:0007416 143 0.017
regulation of glial cell proliferation GO:0060251 11 0.017
central nervous system projection neuron axonogenesis GO:0021952 6 0.017
regulation of smoothened signaling pathway GO:0008589 28 0.017
jnk cascade GO:0007254 50 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
response to endogenous stimulus GO:0009719 119 0.016
midgut development GO:0007494 23 0.016
regulation of histone deacetylation GO:0031063 2 0.016
positive regulation of immune system process GO:0002684 68 0.016
glial cell proliferation GO:0014009 13 0.016
torso signaling pathway GO:0008293 21 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of protein modification process GO:0031399 112 0.016
oocyte construction GO:0007308 112 0.015
regulation of hemocyte differentiation GO:0045610 22 0.015
negative regulation of insulin secretion GO:0046676 1 0.015
cranial nerve development GO:0021545 1 0.015
cellular response to metal ion GO:0071248 6 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.015
positive regulation of stem cell proliferation GO:2000648 8 0.015
germ line stem cell maintenance GO:0030718 50 0.015
epithelial cell migration open tracheal system GO:0007427 32 0.015
determination of adult lifespan GO:0008340 137 0.015
regulation of catabolic process GO:0009894 170 0.015
maintenance of protein location GO:0045185 28 0.014
cellular response to nitrogen compound GO:1901699 51 0.014
response to bacterium GO:0009617 198 0.014
regulation of localization GO:0032879 275 0.014
compound eye cone cell differentiation GO:0042675 13 0.014
photoreceptor cell development GO:0042461 96 0.014
steroid metabolic process GO:0008202 20 0.014
olfactory behavior GO:0042048 97 0.014
negative regulation of growth GO:0045926 84 0.014
wing disc pattern formation GO:0035222 66 0.014
cellular respiration GO:0045333 26 0.014
spermatogenesis GO:0007283 200 0.014
leg disc morphogenesis GO:0007478 80 0.014
establishment of protein localization GO:0045184 163 0.014
developmental cell growth GO:0048588 52 0.013
protein localization to nucleus GO:0034504 55 0.013
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.013
organ induction GO:0001759 3 0.013
regulation of proteolysis GO:0030162 87 0.013
single organismal cell cell adhesion GO:0016337 45 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013

brk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.114
disease of cellular proliferation DOID:14566 0 0.114
organ system cancer DOID:0050686 0 0.114
disease of anatomical entity DOID:7 0 0.088
nervous system disease DOID:863 0 0.079
auditory system disease DOID:2742 0 0.033
sensory system disease DOID:0050155 0 0.033
cardiovascular system disease DOID:1287 0 0.026
musculoskeletal system disease DOID:17 0 0.022
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
physical disorder DOID:0080015 0 0.013
congenital nervous system abnormality DOID:2490 0 0.013