Drosophila melanogaster

19 known processes

Npc2h (Dmel_CG11315)

Niemann-Pick type C-2h

(Aliases: BcDNA:RH04252,BcDNA:RH68460,CG11315,DmML1A,npc2h,BcDNA:GH26608,Dmel\CG11315)

Npc2h biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sterol homeostasis GO:0055092 4 0.055
Fly
salivary gland development GO:0007431 162 0.053
gland development GO:0048732 191 0.051
endocytosis GO:0006897 310 0.049
innate immune response GO:0045087 144 0.045
immune system process GO:0002376 347 0.043
salivary gland cell autophagic cell death GO:0035071 83 0.043
cell death GO:0008219 279 0.041
sensory organ morphogenesis GO:0090596 260 0.041
programmed cell death GO:0012501 257 0.041
developmental programmed cell death GO:0010623 138 0.040
tissue death GO:0016271 102 0.039
death GO:0016265 284 0.036
compound eye development GO:0048749 307 0.036
salivary gland morphogenesis GO:0007435 145 0.034
organic substance catabolic process GO:1901575 308 0.033
eye pigment biosynthetic process GO:0006726 32 0.031
lateral inhibition GO:0046331 206 0.031
histolysis GO:0007559 102 0.031
response to bacterium GO:0009617 198 0.031
Fly
phagocytosis GO:0006909 215 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
gland morphogenesis GO:0022612 145 0.028
salivary gland histolysis GO:0035070 88 0.027
defense response to bacterium GO:0042742 178 0.027
Fly
compound eye morphogenesis GO:0001745 249 0.025
organic cyclic compound catabolic process GO:1901361 168 0.024
autophagic cell death GO:0048102 83 0.024
pigmentation GO:0043473 75 0.024
detection of stimulus GO:0051606 156 0.023
eye development GO:0001654 323 0.023
exocrine system development GO:0035272 162 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
cellular protein modification process GO:0006464 438 0.021
chaeta development GO:0022416 97 0.020
protein modification process GO:0036211 438 0.020
vesicle mediated transport GO:0016192 381 0.020
positive regulation of cell communication GO:0010647 250 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
aromatic compound catabolic process GO:0019439 166 0.020
homeostatic process GO:0042592 199 0.019
Fly
imaginal disc derived appendage development GO:0048737 399 0.019
humoral immune response GO:0006959 117 0.019
defense response GO:0006952 300 0.019
organic substance transport GO:0071702 257 0.018
Fly
kidney development GO:0001822 3 0.018
sulfur compound metabolic process GO:0006790 59 0.018
response to wounding GO:0009611 94 0.018
appendage development GO:0048736 401 0.018
catabolic process GO:0009056 409 0.018
regulation of localization GO:0032879 275 0.017
response to abiotic stimulus GO:0009628 341 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
regionalization GO:0003002 416 0.016
negative regulation of cell communication GO:0010648 223 0.016
cell proliferation GO:0008283 299 0.016
organonitrogen compound metabolic process GO:1901564 318 0.016
regulation of cell cycle GO:0051726 291 0.016
positive regulation of signaling GO:0023056 243 0.015
regulation of transport GO:0051049 181 0.015
response to other organism GO:0051707 293 0.015
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.015
androgen metabolic process GO:0008209 1 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
response to oxygen containing compound GO:1901700 200 0.014
response to lipopolysaccharide GO:0032496 4 0.014
oxoacid metabolic process GO:0043436 103 0.014
body morphogenesis GO:0010171 2 0.014
positive regulation of signal transduction GO:0009967 223 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
regulation of molecular function GO:0065009 217 0.014
phototransduction GO:0007602 52 0.013
dna metabolic process GO:0006259 227 0.013
organelle fission GO:0048285 340 0.013
cell recognition GO:0008037 102 0.013
Fly
actin filament organization GO:0007015 126 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
glycerolipid catabolic process GO:0046503 3 0.013
pigment metabolic process involved in pigmentation GO:0043474 33 0.012
pigment biosynthetic process GO:0046148 36 0.012
regulation of cell death GO:0010941 173 0.012
wing disc morphogenesis GO:0007472 344 0.012
negative regulation of signal transduction GO:0009968 206 0.012
organic acid metabolic process GO:0006082 103 0.012
detection of abiotic stimulus GO:0009582 66 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
negative regulation of signaling GO:0023057 219 0.012
developmental pigmentation GO:0048066 68 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
glutathione metabolic process GO:0006749 37 0.011
single organism biosynthetic process GO:0044711 206 0.011
Fly
positive regulation of lipid storage GO:0010884 4 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
lipid metabolic process GO:0006629 121 0.011
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
regulation of catabolic process GO:0009894 170 0.011
establishment of localization in cell GO:0051649 402 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
organophosphate metabolic process GO:0019637 195 0.011
defense response to other organism GO:0098542 225 0.011
Fly
response to nitrogen compound GO:1901698 90 0.011
response to temperature stimulus GO:0009266 106 0.011
regulation of cell proliferation GO:0042127 163 0.011
organophosphate catabolic process GO:0046434 112 0.011
intracellular signal transduction GO:0035556 300 0.011
nuclear division GO:0000280 332 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
apoptotic process GO:0006915 159 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
eye morphogenesis GO:0048592 260 0.010
steroid metabolic process GO:0008202 20 0.010
Fly
dorsal ventral axis specification GO:0009950 66 0.010
response to hexose GO:0009746 3 0.010
single organism catabolic process GO:0044712 228 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
cellular modified amino acid metabolic process GO:0006575 45 0.010

Npc2h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.012