Drosophila melanogaster

29 known processes

sas-6 (Dmel_CG15524)

spindle assembly abnormal 6

(Aliases: SAS6,DSas6,Dsas6,SAS-6,Dmel\CG15524,Sas-6,dsas-6,DSas-6,DSAS-6,Sas6,CG15524)

sas-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric neuroblast division GO:0055059 33 0.868
neuroblast division GO:0055057 35 0.835
microtubule organizing center organization GO:0031023 168 0.772
centriole replication GO:0007099 24 0.749
centriole assembly GO:0098534 24 0.719
asymmetric stem cell division GO:0098722 49 0.584
centrosome cycle GO:0007098 137 0.567
cellular component assembly involved in morphogenesis GO:0010927 151 0.528
stem cell division GO:0017145 69 0.498
cellular macromolecule localization GO:0070727 220 0.489
centriole centriole cohesion GO:0010457 5 0.466
somatic stem cell division GO:0048103 37 0.437
stem cell proliferation GO:0072089 88 0.362
centrosome duplication GO:0051298 121 0.332
organelle assembly GO:0070925 198 0.323
neuroblast proliferation GO:0007405 74 0.309
cell proliferation GO:0008283 299 0.263
neural precursor cell proliferation GO:0061351 75 0.260
centrosome separation GO:0051299 20 0.253
male gamete generation GO:0048232 201 0.227
cell division GO:0051301 248 0.226
organelle localization GO:0051640 148 0.225
neuronal stem cell division GO:0036445 35 0.185
regulation of microtubule based process GO:0032886 49 0.184
centrosome organization GO:0051297 163 0.181
regulation of mitotic cell cycle GO:0007346 190 0.173
mitotic spindle organization GO:0007052 220 0.172
spermatogenesis GO:0007283 200 0.135
organonitrogen compound metabolic process GO:1901564 318 0.130
blastoderm segmentation GO:0007350 159 0.130
embryonic pattern specification GO:0009880 174 0.108
nucleoside triphosphate metabolic process GO:0009141 120 0.107
regulation of cell cycle GO:0051726 291 0.105
protein complex disassembly GO:0043241 36 0.095
cellular component disassembly GO:0022411 46 0.092
regulation of molecular function GO:0065009 217 0.084
segmentation GO:0035282 207 0.083
catabolic process GO:0009056 409 0.079
cellular protein localization GO:0034613 160 0.079
cilium morphogenesis GO:0060271 39 0.079
regulation of cytoskeleton organization GO:0051493 89 0.078
single organism cellular localization GO:1902580 180 0.077
tripartite regional subdivision GO:0007351 103 0.076
negative regulation of protein depolymerization GO:1901880 23 0.076
cell maturation GO:0048469 144 0.073
protein localization GO:0008104 284 0.071
establishment or maintenance of cell polarity GO:0007163 167 0.069
mitotic centrosome separation GO:0007100 8 0.066
meiotic nuclear division GO:0007126 151 0.065
male meiosis GO:0007140 52 0.062
spermatid differentiation GO:0048515 114 0.061
gland development GO:0048732 191 0.058
male meiosis cytokinesis GO:0007112 26 0.058
asymmetric protein localization GO:0008105 33 0.058
anterior posterior axis specification embryo GO:0008595 103 0.058
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.055
spindle organization GO:0007051 253 0.055
establishment of spindle orientation GO:0051294 18 0.051
vesicle mediated transport GO:0016192 381 0.051
microtubule anchoring GO:0034453 11 0.050
macromolecular complex disassembly GO:0032984 37 0.050
spindle assembly involved in mitosis GO:0090307 50 0.049
endocytosis GO:0006897 310 0.047
regulation of cell development GO:0060284 215 0.047
establishment of organelle localization GO:0051656 122 0.046
organelle fission GO:0048285 340 0.045
mitotic nuclear division GO:0007067 213 0.044
negative regulation of protein complex disassembly GO:0043242 23 0.044
nuclear division GO:0000280 332 0.043
negative regulation of mitotic cell cycle GO:0045930 109 0.043
protein depolymerization GO:0051261 31 0.042
negative regulation of cellular component organization GO:0051129 108 0.039
regulation of hydrolase activity GO:0051336 97 0.039
phosphorylation GO:0016310 294 0.038
protein modification process GO:0036211 438 0.038
negative regulation of developmental process GO:0051093 201 0.038
regulation of phosphorus metabolic process GO:0051174 210 0.037
embryonic axis specification GO:0000578 107 0.037
regulation of growth GO:0040008 233 0.037
small gtpase mediated signal transduction GO:0007264 88 0.037
negative regulation of cytoskeleton organization GO:0051494 30 0.037
oocyte axis specification GO:0007309 108 0.036
cilium assembly GO:0042384 38 0.036
carboxylic acid metabolic process GO:0019752 92 0.035
transcription from rna polymerase ii promoter GO:0006366 368 0.035
sister chromatid segregation GO:0000819 92 0.034
negative regulation of gene expression GO:0010629 387 0.034
response to radiation GO:0009314 155 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.031
ovarian follicle cell development GO:0030707 248 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
regulation of protein complex disassembly GO:0043244 29 0.030
negative regulation of microtubule depolymerization GO:0007026 21 0.029
establishment of cell polarity GO:0030010 40 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.028
regulation of microtubule cytoskeleton organization GO:0070507 41 0.028
eggshell formation GO:0030703 105 0.028
axis specification GO:0009798 167 0.028
developmental maturation GO:0021700 172 0.027
macromolecular complex assembly GO:0065003 256 0.027
regulation of protein depolymerization GO:1901879 27 0.027
protein phosphorylation GO:0006468 169 0.027
organic substance catabolic process GO:1901575 308 0.027
cellular protein modification process GO:0006464 438 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
spindle stabilization GO:0043146 14 0.025
anterior posterior pattern specification GO:0009952 136 0.025
maintenance of location in cell GO:0051651 28 0.025
mitotic cell cycle phase transition GO:0044772 138 0.025
glycosyl compound metabolic process GO:1901657 127 0.025
oxoacid metabolic process GO:0043436 103 0.024
programmed cell death GO:0012501 257 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
sensory perception of mechanical stimulus GO:0050954 72 0.024
negative regulation of transcription dna templated GO:0045892 237 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of microtubule depolymerization GO:0031114 24 0.023
small molecule metabolic process GO:0044281 305 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
organic substance transport GO:0071702 257 0.022
establishment of vesicle localization GO:0051650 51 0.022
cell cycle arrest GO:0007050 4 0.022
peptidyl amino acid modification GO:0018193 105 0.022
microtubule depolymerization GO:0007019 25 0.022
forebrain development GO:0030900 2 0.021
immune system process GO:0002376 347 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
negative regulation of growth GO:0045926 84 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
regulation of neurogenesis GO:0050767 158 0.020
response to organic substance GO:0010033 284 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
body morphogenesis GO:0010171 2 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
chromosome condensation GO:0030261 41 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
microtubule polymerization or depolymerization GO:0031109 39 0.020
maintenance of protein location in cell GO:0032507 26 0.020
response to abiotic stimulus GO:0009628 341 0.019
maintenance of location GO:0051235 73 0.019
microtubule based movement GO:0007018 51 0.019
epithelial cell differentiation GO:0030855 322 0.019
protein localization to organelle GO:0033365 82 0.019
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
establishment of localization in cell GO:0051649 402 0.019
oocyte development GO:0048599 124 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.018
organophosphate metabolic process GO:0019637 195 0.018
spermatid development GO:0007286 98 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
synaptic vesicle endocytosis GO:0048488 28 0.018
embryonic morphogenesis GO:0048598 206 0.018
regulation of cell cycle process GO:0010564 181 0.018
urogenital system development GO:0001655 72 0.018
establishment of mitotic spindle localization GO:0040001 17 0.017
organophosphate catabolic process GO:0046434 112 0.017
positive regulation of immune response GO:0050778 63 0.017
telencephalon development GO:0021537 2 0.017
positive regulation of cell communication GO:0010647 250 0.017
negative regulation of signal transduction GO:0009968 206 0.017
microtubule based transport GO:0010970 42 0.017
mitotic spindle stabilization GO:0043148 6 0.017
pole plasm mrna localization GO:0019094 49 0.017
negative regulation of phosphorus metabolic process GO:0010563 45 0.016
establishment of synaptic vesicle localization GO:0097480 50 0.016
endomembrane system organization GO:0010256 119 0.016
aromatic compound catabolic process GO:0019439 166 0.016
regulation of organelle organization GO:0033043 196 0.016
oocyte construction GO:0007308 112 0.016
immune system development GO:0002520 57 0.016
cell projection assembly GO:0030031 94 0.015
cytokinetic process GO:0032506 27 0.015
cellular protein complex disassembly GO:0043624 35 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
mitotic chromosome condensation GO:0007076 22 0.015
mitotic sister chromatid segregation GO:0000070 87 0.015
maternal determination of anterior posterior axis embryo GO:0008358 74 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of spindle organization GO:0090224 17 0.015
nucleoside metabolic process GO:0009116 127 0.015
renal tubule development GO:0061326 64 0.015
eggshell chorion assembly GO:0007306 66 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.014
negative regulation of cell cycle GO:0045786 116 0.014
establishment of spindle localization GO:0051293 22 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
asymmetric cell division GO:0008356 37 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
heterocycle catabolic process GO:0046700 166 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
cell fate determination GO:0001709 91 0.014
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.014
nucleotide metabolic process GO:0009117 161 0.014
salivary gland development GO:0007431 162 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
regulation of kinase activity GO:0043549 53 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
dna packaging GO:0006323 91 0.014
regulation of wnt signaling pathway GO:0030111 68 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
nucleoside catabolic process GO:0009164 112 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
ras protein signal transduction GO:0007265 88 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
negative regulation of developmental growth GO:0048640 64 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
positive regulation of gene expression GO:0010628 290 0.013
neuromuscular junction development GO:0007528 149 0.013
dna templated transcription initiation GO:0006352 25 0.013
regulation of cellular localization GO:0060341 136 0.013
purine containing compound catabolic process GO:0072523 112 0.013
spermatocyte division GO:0048137 13 0.013
positive regulation of signaling GO:0023056 243 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
spindle assembly involved in male meiosis GO:0007053 5 0.013
chorion containing eggshell formation GO:0007304 105 0.012
positive regulation of signal transduction GO:0009967 223 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
proteolysis GO:0006508 192 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
organic acid metabolic process GO:0006082 103 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
regulation of immune system process GO:0002682 176 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
nuclear envelope organization GO:0006998 7 0.012
single organism membrane organization GO:0044802 93 0.012
meiosis i GO:0007127 59 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
regulation of catalytic activity GO:0050790 185 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
protein polymerization GO:0051258 42 0.012
single organism intracellular transport GO:1902582 207 0.012
rna 3 end processing GO:0031123 45 0.012
regulation of immune response GO:0050776 118 0.012
peptidyl threonine modification GO:0018210 3 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
mitotic cytokinesis GO:0000281 50 0.011
localization of cell GO:0051674 257 0.011
regulation of cell division GO:0051302 72 0.011
macromolecule catabolic process GO:0009057 161 0.011
salivary gland morphogenesis GO:0007435 145 0.011
regulation of transferase activity GO:0051338 58 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
regulation of protein kinase activity GO:0045859 51 0.011
positive regulation of neuron differentiation GO:0045666 26 0.011
synaptic transmission GO:0007268 288 0.011
rna processing GO:0006396 147 0.011
regulation of nervous system development GO:0051960 248 0.011
single organism catabolic process GO:0044712 228 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
oocyte differentiation GO:0009994 145 0.011
negative regulation of molecular function GO:0044092 51 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
regulation of cell projection organization GO:0031344 92 0.011
negative regulation of phosphate metabolic process GO:0045936 45 0.011
developmental growth GO:0048589 280 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
reproductive behavior GO:0019098 122 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
cilium organization GO:0044782 41 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
autophagic cell death GO:0048102 83 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
cellular ketone metabolic process GO:0042180 24 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
cellular protein complex assembly GO:0043623 71 0.010
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.010
taxis GO:0042330 304 0.010
sensory perception GO:0007600 196 0.010
protein transport GO:0015031 155 0.010
meiotic chromosome condensation GO:0010032 3 0.010

sas-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.027
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
disease of metabolism DOID:0014667 0 0.011