Drosophila melanogaster

196 known processes

Dredd (Dmel_CG7486)

Death related ced-3/Nedd2-like protein

(Aliases: Dcp-2/Dredd,DCP2,CG7486,dcp-2/dredd,Dcp2,Dmel\CG7486,DCP-2/DREDD,DREDD,Redd,dredd,EG:115C2.9,Dcp-2,anon-1BCa,DCP-2,Dedd,Dredd/DCP-2)

Dredd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 347 0.995
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.993
regulation of defense response to virus by host GO:0050691 10 0.991
antibacterial humoral response GO:0019731 44 0.978
positive regulation of defense response to virus by host GO:0002230 10 0.974
immune response GO:0006955 246 0.973
humoral immune response GO:0006959 117 0.968
defense response to virus GO:0051607 23 0.931
positive regulation of antimicrobial peptide production GO:0002225 28 0.876
response to virus GO:0009615 28 0.876
positive regulation of biosynthetic process GO:0009891 316 0.851
immune effector process GO:0002252 98 0.851
innate immune response GO:0045087 144 0.848
positive regulation of antibacterial peptide production GO:0002803 20 0.846
regulation of defense response to virus GO:0050688 14 0.822
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.822
regulation of antibacterial peptide production GO:0002786 22 0.788
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.788
positive regulation of endopeptidase activity GO:0010950 26 0.780
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.779
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.736
response to bacterium GO:0009617 198 0.726
regulation of antimicrobial humoral response GO:0002759 50 0.711
regulation of response to biotic stimulus GO:0002831 63 0.711
regulation of response to external stimulus GO:0032101 115 0.691
activation of innate immune response GO:0002218 4 0.689
antimicrobial humoral response GO:0019730 99 0.669
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.651
regulation of multi organism process GO:0043900 131 0.650
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.646
response to other organism GO:0051707 293 0.624
antimicrobial peptide production GO:0002775 46 0.619
regulation of humoral immune response GO:0002920 51 0.612
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.593
regulation of defense response GO:0031347 102 0.582
positive regulation of immune effector process GO:0002699 28 0.581
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.581
positive regulation of response to external stimulus GO:0032103 44 0.580
defense response GO:0006952 300 0.577
peptide metabolic process GO:0006518 80 0.561
response to external biotic stimulus GO:0043207 293 0.544
regulation of antimicrobial peptide production GO:0002784 44 0.518
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.495
positive regulation of defense response to bacterium GO:1900426 23 0.492
defense response to other organism GO:0098542 225 0.484
positive regulation of antimicrobial humoral response GO:0002760 28 0.472
response to biotic stimulus GO:0009607 294 0.469
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.466
organonitrogen compound biosynthetic process GO:1901566 117 0.464
cellular amide metabolic process GO:0043603 80 0.428
cellular response to dna damage stimulus GO:0006974 223 0.427
Human
positive regulation of humoral immune response GO:0002922 28 0.419
organonitrogen compound metabolic process GO:1901564 318 0.414
activation of cysteine type endopeptidase activity GO:0097202 17 0.410
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.405
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.404
regulation of innate immune response GO:0045088 71 0.397
positive regulation of cellular biosynthetic process GO:0031328 316 0.376
response to peptidoglycan GO:0032494 2 0.370
innate immune response activating signal transduction GO:0002758 2 0.351
regulation of cysteine type endopeptidase activity GO:2000116 27 0.348
zymogen activation GO:0031638 20 0.341
cell cycle checkpoint GO:0000075 95 0.337
Human
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.331
programmed cell death GO:0012501 257 0.330
cellular response to abiotic stimulus GO:0071214 58 0.325
Human
antibacterial peptide biosynthetic process GO:0002780 22 0.313
positive regulation of defense response GO:0031349 59 0.312
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.307
regulation of immune response GO:0050776 118 0.306
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.303
antibacterial peptide production GO:0002778 22 0.291
response to oxidative stress GO:0006979 86 0.289
positive regulation of immune response GO:0050778 63 0.287
positive regulation of response to stimulus GO:0048584 323 0.273
positive regulation of transcription dna templated GO:0045893 266 0.272
Fly
positive regulation of cellular amide metabolic process GO:0034250 26 0.270
regulation of immune system process GO:0002682 176 0.269
defense response to gram negative bacterium GO:0050829 94 0.261
immune response activating signal transduction GO:0002757 2 0.256
transcription from rna polymerase ii promoter GO:0006366 368 0.242
antimicrobial peptide biosynthetic process GO:0002777 38 0.239
positive regulation of multi organism process GO:0043902 40 0.239
dna metabolic process GO:0006259 227 0.234
regulation of immune effector process GO:0002697 52 0.229
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.223
positive regulation of proteolysis GO:0045862 52 0.223
amide biosynthetic process GO:0043604 42 0.220
response to oxygen radical GO:0000305 3 0.215
defense response to bacterium GO:0042742 178 0.215
mitotic dna integrity checkpoint GO:0044774 75 0.206
Human
production of molecular mediator of immune response GO:0002440 46 0.203
regulation of endopeptidase activity GO:0052548 36 0.201
pattern recognition receptor signaling pathway GO:0002221 2 0.199
regulation of cellular amide metabolic process GO:0034248 39 0.199
positive regulation of rna biosynthetic process GO:1902680 266 0.188
Fly
regulation of cell death GO:0010941 173 0.184
negative regulation of cell cycle phase transition GO:1901988 103 0.182
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.179
intracellular protein transport GO:0006886 104 0.173
developmental programmed cell death GO:0010623 138 0.172
Mouse Fly
regulation of response to stress GO:0080134 200 0.162
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.159
Fly
regulation of programmed cell death GO:0043067 152 0.156
regulation of cell cycle process GO:0010564 181 0.154
Human
proteolysis GO:0006508 192 0.151
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.150
Fly
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.149
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.148
Fly
positive regulation of response to biotic stimulus GO:0002833 31 0.142
cell cycle phase transition GO:0044770 140 0.141
Human
gland morphogenesis GO:0022612 145 0.137
Fly
dna integrity checkpoint GO:0031570 81 0.134
Human
regulation of stem cell proliferation GO:0072091 40 0.133
developmental maturation GO:0021700 172 0.132
Fly
negative regulation of cell cycle process GO:0010948 109 0.131
Human
immune response regulating signaling pathway GO:0002764 2 0.130
carbohydrate derivative metabolic process GO:1901135 217 0.129
antifungal peptide production GO:0002781 7 0.129
regulation of intracellular signal transduction GO:1902531 236 0.126
Human Mouse
cell proliferation GO:0008283 299 0.122
Fly
defense response to gram positive bacterium GO:0050830 41 0.120
positive regulation of rna metabolic process GO:0051254 271 0.117
Fly
glycosaminoglycan catabolic process GO:0006027 3 0.116
positive regulation of signaling GO:0023056 243 0.116
Human Mouse Fly
sperm individualization GO:0007291 48 0.114
regulation of proteolysis GO:0030162 87 0.112
salivary gland development GO:0007431 162 0.110
Fly
positive regulation of cell communication GO:0010647 250 0.110
Human Mouse Fly
cell maturation GO:0048469 144 0.109
Fly
positive regulation of hydrolase activity GO:0051345 78 0.108
small molecule metabolic process GO:0044281 305 0.107
protein maturation GO:0051604 71 0.106
negative regulation of defense response to bacterium GO:1900425 7 0.105
positive regulation of immune system process GO:0002684 68 0.104
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.103
Fly
negative regulation of gene expression GO:0010629 387 0.103
single organism carbohydrate metabolic process GO:0044723 72 0.101
post embryonic appendage morphogenesis GO:0035120 385 0.100
regulation of defense response to bacterium GO:1900424 30 0.100
regionalization GO:0003002 416 0.099
positive regulation of antifungal peptide production GO:0002804 6 0.096
appendage morphogenesis GO:0035107 397 0.095
mitotic nuclear division GO:0007067 213 0.090
neuron projection guidance GO:0097485 241 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.090
Human
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.089
positive regulation of innate immune response GO:0045089 38 0.089
cellular protein modification process GO:0006464 438 0.088
positive regulation of macromolecule metabolic process GO:0010604 405 0.088
wing disc morphogenesis GO:0007472 344 0.087
negative regulation of multicellular organismal process GO:0051241 142 0.087
positive regulation of nucleic acid templated transcription GO:1903508 266 0.087
Fly
positive regulation of nervous system development GO:0051962 69 0.087
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.085
negative regulation of mitotic cell cycle GO:0045930 109 0.085
Human
gland development GO:0048732 191 0.084
Fly
regulation of cell proliferation GO:0042127 163 0.083
Fly
regulation of antifungal peptide production GO:0002788 6 0.083
regulation of cell differentiation GO:0045595 302 0.083
Fly
dna damage checkpoint GO:0000077 78 0.081
Human
response to lipopolysaccharide GO:0032496 4 0.081
Mouse Rat
melanization defense response GO:0035006 45 0.081
Fly
mitotic cell cycle checkpoint GO:0007093 88 0.080
Human
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.080
regulation of developmental growth GO:0048638 174 0.079
positive regulation of peptidase activity GO:0010952 29 0.078
epithelial structure maintenance GO:0010669 17 0.077
tissue morphogenesis GO:0048729 297 0.077
regulation of molecular function GO:0065009 217 0.076
cell migration GO:0016477 238 0.074
cell death GO:0008219 279 0.074
death GO:0016265 284 0.074
paracrine signaling GO:0038001 7 0.074
positive regulation of molecular function GO:0044093 136 0.073
regulation of cellular response to oxidative stress GO:1900407 4 0.072
peptide biosynthetic process GO:0043043 42 0.072
intracellular signal transduction GO:0035556 300 0.072
Human Mouse
establishment of localization in cell GO:0051649 402 0.071
Mouse Rat
negative regulation of apoptotic process GO:0043066 63 0.071
transmembrane transport GO:0055085 139 0.071
cellular response to molecule of bacterial origin GO:0071219 3 0.070
regulation of localization GO:0032879 275 0.070
Mouse Rat
regulation of multicellular organismal development GO:2000026 414 0.069
Fly
anatomical structure homeostasis GO:0060249 97 0.069
stem cell proliferation GO:0072089 88 0.069
negative regulation of biosynthetic process GO:0009890 277 0.069
axonogenesis GO:0007409 290 0.067
vesicle mediated transport GO:0016192 381 0.067
Worm
regulation of catalytic activity GO:0050790 185 0.067
positive regulation of gene expression GO:0010628 290 0.066
Fly
g2 dna damage checkpoint GO:0031572 69 0.066
axon guidance GO:0007411 233 0.065
phosphorylation GO:0016310 294 0.065
regulation of intracellular transport GO:0032386 64 0.065
ovarian follicle cell development GO:0030707 248 0.064
intracellular transport GO:0046907 228 0.063
locomotory behavior GO:0007626 176 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.062
regulation of mitotic cell cycle GO:0007346 190 0.062
Human
regulation of protein localization GO:0032880 76 0.061
Mouse Rat
single organism intracellular transport GO:1902582 207 0.061
adult behavior GO:0030534 137 0.060
carbohydrate derivative biosynthetic process GO:1901137 85 0.060
organophosphate metabolic process GO:0019637 195 0.060
negative regulation of cellular metabolic process GO:0031324 382 0.060
single organism behavior GO:0044708 391 0.059
Rat
mitotic dna damage checkpoint GO:0044773 74 0.059
Human
regulation of cell cycle GO:0051726 291 0.059
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.058
Human Mouse
regulation of production of molecular mediator of immune response GO:0002700 44 0.057
imaginal disc derived wing morphogenesis GO:0007476 337 0.056
macromolecule catabolic process GO:0009057 161 0.056
Worm
regulation of defense response to fungus GO:1900150 6 0.056
response to radiation GO:0009314 155 0.055
Fly
apoptotic process GO:0006915 159 0.054
organic hydroxy compound metabolic process GO:1901615 83 0.054
Fly
response to superoxide GO:0000303 3 0.054
negative regulation of neuron death GO:1901215 18 0.052
positive regulation of apoptotic process GO:0043065 47 0.052
positive regulation of cell death GO:0010942 69 0.052
response to copper ion GO:0046688 4 0.050
epithelial cell differentiation GO:0030855 322 0.050
positive regulation of signal transduction GO:0009967 223 0.050
Human Mouse Fly
epithelial cell development GO:0002064 274 0.049
protein ubiquitination GO:0016567 70 0.049
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.048
salivary gland morphogenesis GO:0007435 145 0.048
Fly
regulation of phosphate metabolic process GO:0019220 210 0.048
positive regulation of cellular catabolic process GO:0031331 95 0.048
Fly
negative regulation of stem cell proliferation GO:2000647 30 0.048
actin filament based movement GO:0030048 26 0.047
regulation of response to oxidative stress GO:1902882 4 0.047
exocrine system development GO:0035272 162 0.047
Fly
cytoplasmic transport GO:0016482 130 0.047
antifungal peptide biosynthetic process GO:0002783 5 0.047
regulation of cellular response to stress GO:0080135 89 0.045
Fly
mrna metabolic process GO:0016071 124 0.045
regulation of growth GO:0040008 233 0.045
regulation of protein metabolic process GO:0051246 256 0.045
regulation of peptidase activity GO:0052547 39 0.044
neurological system process GO:0050877 358 0.044
Rat
carbohydrate metabolic process GO:0005975 82 0.044
body morphogenesis GO:0010171 2 0.043
cellular response to lipopolysaccharide GO:0071222 3 0.043
growth GO:0040007 359 0.043
negative regulation of developmental process GO:0051093 201 0.043
morphogenesis of an epithelium GO:0002009 276 0.043
multicellular organismal homeostasis GO:0048871 41 0.043
male gamete generation GO:0048232 201 0.043
regulation of cellular component size GO:0032535 98 0.042
cellular response to mechanical stimulus GO:0071260 2 0.042
Human
regulation of cell cycle phase transition GO:1901987 130 0.040
Human
cellular response to biotic stimulus GO:0071216 4 0.040
appendage development GO:0048736 401 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.039
response to abiotic stimulus GO:0009628 341 0.039
Human Mouse Rat Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.039
positive regulation of protein metabolic process GO:0051247 128 0.039
negative regulation of cell death GO:0060548 81 0.038
regulation of hydrolase activity GO:0051336 97 0.038
response to oxygen containing compound GO:1901700 200 0.038
Mouse Rat
dorsal ventral axis specification GO:0009950 66 0.037
nuclear division GO:0000280 332 0.037
salivary gland cell autophagic cell death GO:0035071 83 0.037
Fly
neuron death GO:0070997 27 0.037
Rat
homeostatic process GO:0042592 199 0.037
skin development GO:0043588 65 0.037
establishment of tissue polarity GO:0007164 87 0.036
protein localization GO:0008104 284 0.036
Mouse Rat
regulation of cellular catabolic process GO:0031329 157 0.036
Mouse Fly
regulation of protein import into nucleus GO:0042306 28 0.036
regulation of phosphorylation GO:0042325 147 0.036
response to organic cyclic compound GO:0014070 89 0.035
Mouse Rat
mitotic spindle organization GO:0007052 220 0.034
cellular catabolic process GO:0044248 372 0.034
Mouse Fly
regulation of protein transport GO:0051223 57 0.034
Mouse Rat
cellular protein localization GO:0034613 160 0.034
aromatic compound catabolic process GO:0019439 166 0.033
tube morphogenesis GO:0035239 191 0.033
membrane organization GO:0061024 112 0.032
Worm
compound eye morphogenesis GO:0001745 249 0.032
Fly
wnt signaling pathway GO:0016055 98 0.032
dendrite morphogenesis GO:0048813 199 0.032
Fly
catabolic process GO:0009056 409 0.032
Mouse Worm Fly
regulation of jnk cascade GO:0046328 40 0.032
jak stat cascade GO:0007259 49 0.032
cellularization GO:0007349 90 0.032
heterocycle catabolic process GO:0046700 166 0.032
embryonic morphogenesis GO:0048598 206 0.031
Fly
regulation of dna templated transcription in response to stress GO:0043620 4 0.031
negative regulation of cell differentiation GO:0045596 143 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
multicellular organismal aging GO:0010259 140 0.031
Worm Fly
positive regulation of multicellular organismal process GO:0051240 143 0.031
Mouse Rat Fly
negative regulation of programmed cell death GO:0043069 72 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.030
sensory organ morphogenesis GO:0090596 260 0.030
Fly
nucleotide metabolic process GO:0009117 161 0.030
respiratory system development GO:0060541 213 0.030
Rat
autophagic cell death GO:0048102 83 0.030
Fly
nucleocytoplasmic transport GO:0006913 72 0.030
regulation of autophagy GO:0010506 62 0.030
Mouse Fly
asymmetric cell division GO:0008356 37 0.030
germ line stem cell maintenance GO:0030718 50 0.030
digestive tract morphogenesis GO:0048546 127 0.029
periodic partitioning GO:0007365 29 0.029
protein modification process GO:0036211 438 0.029
response to alcohol GO:0097305 95 0.029
Rat
cell motility GO:0048870 251 0.029
peripheral nervous system development GO:0007422 52 0.029
negative regulation of response to external stimulus GO:0032102 22 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
regulation of establishment of protein localization GO:0070201 61 0.029
Mouse Rat
regulation of neurogenesis GO:0050767 158 0.029
extrinsic apoptotic signaling pathway GO:0097191 1 0.028
Mouse
jnk cascade GO:0007254 50 0.028
regulation of apoptotic process GO:0042981 130 0.028
positive regulation of intracellular signal transduction GO:1902533 116 0.027
Human Mouse
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
Human Mouse
pigmentation GO:0043473 75 0.027
dendrite development GO:0016358 204 0.026
Fly
immune system development GO:0002520 57 0.026
salivary gland histolysis GO:0035070 88 0.026
Fly
synapse organization GO:0050808 196 0.026
endocytosis GO:0006897 310 0.026
Worm
regulation of intracellular protein transport GO:0033157 46 0.026
adult locomotory behavior GO:0008344 76 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
response to starvation GO:0042594 97 0.026
Fly
small rna loading onto risc GO:0070922 6 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
regulation of cell development GO:0060284 215 0.026
Fly
regulation of epithelial cell differentiation GO:0030856 4 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
lipid metabolic process GO:0006629 121 0.025
cell type specific apoptotic process GO:0097285 38 0.025
Rat Fly
positive regulation of cell differentiation GO:0045597 64 0.025
Fly
forebrain development GO:0030900 2 0.025
cellular response to organic substance GO:0071310 132 0.025
Human Mouse
response to organic substance GO:0010033 284 0.025
Human Mouse Rat
protein import into nucleus GO:0006606 51 0.025
fat soluble vitamin metabolic process GO:0006775 1 0.024
positive regulation of developmental process GO:0051094 143 0.024
Fly
negative regulation of signaling GO:0023057 219 0.024
Fly
regulation of neuron death GO:1901214 26 0.024
Rat
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
tissue death GO:0016271 102 0.024
Fly
ovarian follicle cell migration GO:0007297 121 0.024
reactive oxygen species metabolic process GO:0072593 22 0.024
regulation of wnt signaling pathway GO:0030111 68 0.024
phagocytosis GO:0006909 215 0.024
Worm
actin filament based process GO:0030029 220 0.024
response to mechanical stimulus GO:0009612 28 0.023
Human
metal ion homeostasis GO:0055065 44 0.023
taxis GO:0042330 304 0.023
mucosal immune response GO:0002385 10 0.023
response to dsrna GO:0043331 15 0.023
regulation of nervous system development GO:0051960 248 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
nuclear transport GO:0051169 72 0.023
peptidoglycan catabolic process GO:0009253 3 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
establishment of planar polarity GO:0001736 87 0.022
cellular response to oxygen containing compound GO:1901701 79 0.022
negative regulation of innate immune response GO:0045824 30 0.022
chemotaxis GO:0006935 249 0.022
cellular macromolecule localization GO:0070727 220 0.022
ameboidal type cell migration GO:0001667 151 0.022
cell fate determination GO:0001709 91 0.022
organophosphate biosynthetic process GO:0090407 46 0.022
negative regulation of signal transduction GO:0009968 206 0.022
intracellular protein transmembrane transport GO:0065002 4 0.021
regulation of multicellular organism growth GO:0040014 40 0.021
positive regulation of programmed cell death GO:0043068 62 0.021
protein processing GO:0016485 68 0.021
embryonic pattern specification GO:0009880 174 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
oxoacid metabolic process GO:0043436 103 0.021
regulation of cellular localization GO:0060341 136 0.021
Mouse Rat
nuclear import GO:0051170 51 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
single organism cellular localization GO:1902580 180 0.021
negative regulation of cell cycle GO:0045786 116 0.021
Human
mitotic cytokinesis GO:0000281 50 0.020
organic substance catabolic process GO:1901575 308 0.020
Worm
spermatid differentiation GO:0048515 114 0.020
eye development GO:0001654 323 0.020
Rat Fly
protein catabolic process GO:0030163 101 0.020
Worm
regulation of chromosome organization GO:0033044 64 0.020
regulation of developmental pigmentation GO:0048070 24 0.020
rna processing GO:0006396 147 0.019
response to reactive oxygen species GO:0000302 24 0.019
regulation of mapk cascade GO:0043408 92 0.019
positive regulation of cell development GO:0010720 61 0.019
Fly
organic substance transport GO:0071702 257 0.019
Mouse Rat
negative regulation of growth GO:0045926 84 0.019
molting cycle GO:0042303 56 0.019
blastoderm segmentation GO:0007350 159 0.019
single organism catabolic process GO:0044712 228 0.019
Fly
neuron apoptotic process GO:0051402 17 0.019
Rat
organelle localization GO:0051640 148 0.019
multi organism behavior GO:0051705 175 0.019
establishment of protein localization GO:0045184 163 0.019
Mouse Rat
positive regulation of transport GO:0051050 92 0.019
Mouse Rat
regulation of organ morphogenesis GO:2000027 78 0.019
Fly
dna repair GO:0006281 54 0.018
response to molecule of bacterial origin GO:0002237 7 0.018
Mouse Rat
negative regulation of rna metabolic process GO:0051253 251 0.018
melanotic encapsulation of foreign target GO:0035011 30 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
Fly
chromatin modification GO:0016568 147 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
Human
response to toxic substance GO:0009636 22 0.018
Rat
regulation of melanization defense response GO:0035007 6 0.018
defense response to fungus GO:0050832 48 0.018
mitotic g2 m transition checkpoint GO:0044818 70 0.018
organ or tissue specific immune response GO:0002251 10 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
regulation of anatomical structure size GO:0090066 163 0.018
maintenance of gastrointestinal epithelium GO:0030277 3 0.018
mitotic g2 dna damage checkpoint GO:0007095 69 0.018
compound eye development GO:0048749 307 0.018
Fly
purine nucleotide metabolic process GO:0006163 146 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.017
Human Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.017
regulation of reactive oxygen species metabolic process GO:2000377 8 0.017
organic acid metabolic process GO:0006082 103 0.017
antifungal humoral response GO:0019732 12 0.017
pigment metabolic process GO:0042440 84 0.017
Fly
protein modification by small protein conjugation GO:0032446 79 0.017
estrogen metabolic process GO:0008210 1 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
Mouse Fly
regulation of transport GO:0051049 181 0.017
Mouse Rat
ribonucleotide metabolic process GO:0009259 145 0.017
regulation of nucleocytoplasmic transport GO:0046822 35 0.017
necrotic cell death GO:0070265 1 0.017
Mouse
retina development in camera type eye GO:0060041 4 0.017
Rat
chemical homeostasis GO:0048878 92 0.017
hydrogen peroxide catabolic process GO:0042744 6 0.017
chromosome organization GO:0051276 360 0.017
response to glucose GO:0009749 2 0.017
morphogenesis of follicular epithelium GO:0016333 36 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
negative regulation of immune response GO:0050777 39 0.016
cellular response to ionizing radiation GO:0071479 15 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
localization of cell GO:0051674 257 0.016
regulation of mrna metabolic process GO:1903311 72 0.016
oxidation reduction process GO:0055114 123 0.016
oocyte dorsal ventral axis specification GO:0007310 34 0.016
negative regulation of cell communication GO:0010648 223 0.016
Fly
protein complex assembly GO:0006461 200 0.016
Fly
tissue migration GO:0090130 155 0.016
metal ion transport GO:0030001 74 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
energy derivation by oxidation of organic compounds GO:0015980 32 0.016
mitochondrion degradation GO:0000422 8 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
segment polarity determination GO:0007367 25 0.016
tube development GO:0035295 244 0.016
Rat
secondary metabolic process GO:0019748 75 0.016
Fly
response to lipid GO:0033993 38 0.016
Mouse Rat
posttranscriptional gene silencing by rna GO:0035194 45 0.016
protein localization to organelle GO:0033365 82 0.016
purine containing compound metabolic process GO:0072521 155 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
positive regulation of wnt signaling pathway GO:0030177 25 0.015
negative regulation of developmental growth GO:0048640 64 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
cell junction organization GO:0034330 57 0.015
cell division GO:0051301 248 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
organic hydroxy compound biosynthetic process GO:1901617 21 0.015
reproductive structure development GO:0048608 74 0.015
Rat
regulation of stress activated mapk cascade GO:0032872 41 0.015
i kappab phosphorylation GO:0007252 3 0.015
interspecies interaction between organisms GO:0044419 16 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
cell recognition GO:0008037 102 0.015
associative learning GO:0008306 65 0.015
chaeta morphogenesis GO:0008407 42 0.015
neuron remodeling GO:0016322 29 0.015
Fly
positive regulation of cellular component organization GO:0051130 156 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015

Dredd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
disease of cellular proliferation DOID:14566 0 0.058
cancer DOID:162 0 0.041
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.017