Drosophila melanogaster

326 known processes

hep (Dmel_CG4353)

hemipterous

(Aliases: CG2190,l(1)G0107,Dmel\CG4353,dJNKK,Hep,l(1)G0208,D-MKK7,hp,DMKK7,DHEP/MKK7,Mkk7,Hep/Mkk7,DJNKK,MKK7,MAPKK,HEP/MKK7,HEP,l(1)7P1,hem,JNKK,CG4353)

hep biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 302 1.000
negative regulation of transcription dna templated GO:0045892 237 1.000
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.999
negative regulation of nucleic acid templated transcription GO:1903507 240 0.999
negative regulation of cell communication GO:0010648 223 0.998
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.998
morphogenesis of an epithelium GO:0002009 276 0.997
tissue morphogenesis GO:0048729 297 0.997
immune system process GO:0002376 347 0.996
negative regulation of cellular metabolic process GO:0031324 382 0.996
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.995
negative regulation of rna biosynthetic process GO:1902679 240 0.995
cell proliferation GO:0008283 299 0.994
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.993
positive regulation of macromolecule metabolic process GO:0010604 405 0.992
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.992
negative regulation of rna metabolic process GO:0051253 251 0.992
regulation of immune system process GO:0002682 176 0.991
embryonic morphogenesis GO:0048598 206 0.989
actin cytoskeleton organization GO:0030036 206 0.985
cell death GO:0008219 279 0.984
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.980
regulation of cell proliferation GO:0042127 163 0.979
developmental growth GO:0048589 280 0.978
negative regulation of gene expression GO:0010629 387 0.977
tube morphogenesis GO:0035239 191 0.974
positive regulation of cellular biosynthetic process GO:0031328 316 0.972
cellular response to extracellular stimulus GO:0031668 64 0.969
negative regulation of biosynthetic process GO:0009890 277 0.966
negative regulation of signal transduction GO:0009968 206 0.966
enzyme linked receptor protein signaling pathway GO:0007167 179 0.961
negative regulation of signaling GO:0023057 219 0.960
developmental programmed cell death GO:0010623 138 0.960
digestive tract development GO:0048565 149 0.958
tissue migration GO:0090130 155 0.957
growth GO:0040007 359 0.957
tube development GO:0035295 244 0.956
transcription from rna polymerase ii promoter GO:0006366 368 0.950
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.947
negative regulation of cellular biosynthetic process GO:0031327 277 0.943
regulation of anatomical structure morphogenesis GO:0022603 242 0.938
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.938
epithelial cell differentiation GO:0030855 322 0.932
positive regulation of nucleic acid templated transcription GO:1903508 266 0.932
negative regulation of wnt signaling pathway GO:0030178 28 0.931
imaginal disc fusion GO:0046528 19 0.930
positive regulation of gene expression GO:0010628 290 0.925
positive regulation of rna metabolic process GO:0051254 271 0.921
regulation of multicellular organismal development GO:2000026 414 0.915
Fly
dna metabolic process GO:0006259 227 0.905
regulation of nervous system development GO:0051960 248 0.904
death GO:0016265 284 0.894
Rat
cell migration GO:0016477 238 0.886
negative regulation of response to stimulus GO:0048585 258 0.886
columnar cuboidal epithelial cell development GO:0002066 249 0.876
actin filament based process GO:0030029 220 0.873
response to organic substance GO:0010033 284 0.872
Human Rat
establishment of planar polarity GO:0001736 87 0.871
positive regulation of transcription dna templated GO:0045893 266 0.869
dorsal appendage formation GO:0046843 47 0.867
photoreceptor cell differentiation GO:0046530 170 0.865
cellular response to chemical stimulus GO:0070887 199 0.859
wing disc morphogenesis GO:0007472 344 0.851
actin filament organization GO:0007015 126 0.836
regulation of cell death GO:0010941 173 0.834
Rat
r3 r4 cell fate commitment GO:0007464 10 0.830
programmed cell death GO:0012501 257 0.829
Rat
negative regulation of cell proliferation GO:0008285 69 0.829
regulation of intracellular signal transduction GO:1902531 236 0.808
imaginal disc derived wing morphogenesis GO:0007476 337 0.806
positive regulation of cell death GO:0010942 69 0.805
Rat
stress activated mapk cascade GO:0051403 52 0.799
imaginal disc derived appendage morphogenesis GO:0035114 395 0.798
regulation of cell morphogenesis GO:0022604 163 0.797
regulation of cellular localization GO:0060341 136 0.792
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.787
positive regulation of biosynthetic process GO:0009891 316 0.785
compound eye development GO:0048749 307 0.778
negative regulation of cell differentiation GO:0045596 143 0.777
mapk cascade GO:0000165 107 0.776
embryonic development via the syncytial blastoderm GO:0001700 148 0.774
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.763
response to nutrient levels GO:0031667 114 0.760
Worm
chorion containing eggshell formation GO:0007304 105 0.754
dorsal closure GO:0007391 79 0.753
photoreceptor cell fate commitment GO:0046552 41 0.750
eggshell formation GO:0030703 105 0.743
positive regulation of protein kinase activity GO:0045860 25 0.736
regulation of cell shape GO:0008360 113 0.736
epithelial cell development GO:0002064 274 0.734
cell cycle dna replication GO:0044786 23 0.728
regulation of programmed cell death GO:0043067 152 0.728
Rat
organ growth GO:0035265 56 0.726
compound eye photoreceptor cell differentiation GO:0001751 140 0.708
regulation of cellular component biogenesis GO:0044087 201 0.703
tissue death GO:0016271 102 0.692
positive regulation of secretion GO:0051047 22 0.690
digestive system development GO:0055123 149 0.688
positive regulation of cellular component biogenesis GO:0044089 80 0.663
cell cycle g1 s phase transition GO:0044843 31 0.662
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.662
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.659
positive regulation of cell communication GO:0010647 250 0.645
establishment of ommatidial planar polarity GO:0042067 49 0.640
open tracheal system development GO:0007424 204 0.637
intracellular protein transport GO:0006886 104 0.636
dendrite morphogenesis GO:0048813 199 0.630
r3 r4 cell differentiation GO:0048056 12 0.622
epidermis development GO:0008544 65 0.621
protein phosphorylation GO:0006468 169 0.614
regulation of cell development GO:0060284 215 0.610
activation of mapk activity GO:0000187 9 0.609
Human Mouse Rat Worm Fly
imaginal disc derived appendage development GO:0048737 399 0.606
response to extracellular stimulus GO:0009991 116 0.599
Worm
establishment of tissue polarity GO:0007164 87 0.597
respiratory system development GO:0060541 213 0.587
regulation of cellular catabolic process GO:0031329 157 0.587
anterior posterior pattern specification GO:0009952 136 0.586
Zebrafish
cellular response to external stimulus GO:0071496 66 0.584
cellular catabolic process GO:0044248 372 0.579
compound eye morphogenesis GO:0001745 249 0.576
stress activated protein kinase signaling cascade GO:0031098 55 0.571
appendage development GO:0048736 401 0.568
autophagic vacuole assembly GO:0000045 2 0.567
malpighian tubule development GO:0072002 64 0.564
negative regulation of growth GO:0045926 84 0.555
cellular response to organic substance GO:0071310 132 0.552
Rat
skin development GO:0043588 65 0.551
appendage morphogenesis GO:0035107 397 0.547
response to alcohol GO:0097305 95 0.538
epidermal cell differentiation GO:0009913 51 0.537
digestive tract morphogenesis GO:0048546 127 0.533
positive regulation of cell differentiation GO:0045597 64 0.531
exocrine system development GO:0035272 162 0.530
initiation of dorsal closure GO:0007392 12 0.528
cell fate specification GO:0001708 71 0.523
autophagy GO:0006914 108 0.521
sensory organ morphogenesis GO:0090596 260 0.519
regulation of apoptotic process GO:0042981 130 0.519
Rat
cell motility GO:0048870 251 0.512
cellular response to nutrient levels GO:0031669 62 0.509
regulation of mapk cascade GO:0043408 92 0.501
embryo development ending in birth or egg hatching GO:0009792 152 0.498
eye development GO:0001654 323 0.495
regulation of organelle organization GO:0033043 196 0.493
cellular protein modification process GO:0006464 438 0.491
positive regulation of immune system process GO:0002684 68 0.489
negative regulation of phosphate metabolic process GO:0045936 45 0.488
regulation of organ growth GO:0046620 42 0.473
gland development GO:0048732 191 0.464
regulation of response to stress GO:0080134 200 0.462
catabolic process GO:0009056 409 0.451
negative regulation of intracellular signal transduction GO:1902532 57 0.450
regulation of actin cytoskeleton organization GO:0032956 42 0.447
protein targeting to nucleus GO:0044744 51 0.447
positive regulation of rna biosynthetic process GO:1902680 266 0.447
positive regulation of multicellular organismal process GO:0051240 143 0.445
response to radiation GO:0009314 155 0.439
Human
actin filament bundle assembly GO:0051017 26 0.438
dorsal ventral axis specification GO:0009950 66 0.436
homeostatic process GO:0042592 199 0.435
epithelial cell type specification open tracheal system GO:0035153 11 0.430
cardiac cell fate commitment GO:0060911 17 0.430
morphogenesis of a polarized epithelium GO:0001738 93 0.426
cuticle development GO:0042335 86 0.421
Fly
peptidyl amino acid modification GO:0018193 105 0.420
developmental growth involved in morphogenesis GO:0060560 65 0.418
neurological system process GO:0050877 358 0.412
response to oxygen containing compound GO:1901700 200 0.411
Rat
hematopoietic or lymphoid organ development GO:0048534 57 0.410
gland morphogenesis GO:0022612 145 0.409
negative regulation of molecular function GO:0044092 51 0.408
regulation of protein metabolic process GO:0051246 256 0.405
regionalization GO:0003002 416 0.403
activation of protein kinase activity GO:0032147 12 0.401
Human Mouse Rat Worm Fly
protein transport GO:0015031 155 0.401
genital disc development GO:0035215 44 0.399
positive regulation of developmental process GO:0051094 143 0.396
negative regulation of programmed cell death GO:0043069 72 0.396
axon development GO:0061564 297 0.388
establishment or maintenance of cell polarity GO:0007163 167 0.386
central nervous system development GO:0007417 201 0.386
protein import into nucleus GO:0006606 51 0.381
ovarian follicle cell migration GO:0007297 121 0.379
regulation of protein transport GO:0051223 57 0.377
gastrulation GO:0007369 70 0.377
positive regulation of intracellular signal transduction GO:1902533 116 0.377
positive regulation of signaling GO:0023056 243 0.375
sex differentiation GO:0007548 81 0.372
response to growth factor GO:0070848 31 0.368
cellular macromolecule localization GO:0070727 220 0.366
muscle tissue development GO:0060537 30 0.364
positive regulation of programmed cell death GO:0043068 62 0.364
Rat
regulation of map kinase activity GO:0043405 17 0.358
oocyte axis specification GO:0007309 108 0.355
stem cell maintenance GO:0019827 67 0.351
regulation of catalytic activity GO:0050790 185 0.343
post embryonic appendage morphogenesis GO:0035120 385 0.335
eye photoreceptor cell differentiation GO:0001754 145 0.327
cellular response to starvation GO:0009267 61 0.325
border follicle cell migration GO:0007298 113 0.322
regulation of establishment of protein localization GO:0070201 61 0.315
regulation of growth GO:0040008 233 0.314
Worm
wnt signaling pathway GO:0016055 98 0.313
humoral immune response GO:0006959 117 0.313
compound eye photoreceptor development GO:0042051 78 0.313
germarium derived egg chamber formation GO:0007293 101 0.313
regulation of neuron differentiation GO:0045664 103 0.312
cell adhesion GO:0007155 136 0.307
regulation of neurogenesis GO:0050767 158 0.304
response to oxidative stress GO:0006979 86 0.300
negative regulation of apoptotic process GO:0043066 63 0.298
regulation of cellular protein metabolic process GO:0032268 243 0.294
regulation of phosphate metabolic process GO:0019220 210 0.291
ovarian follicle cell development GO:0030707 248 0.288
cell type specific apoptotic process GO:0097285 38 0.287
Rat
dorsal closure elongation of leading edge cells GO:0007394 10 0.286
regulation of jnk cascade GO:0046328 40 0.281
regulation of catabolic process GO:0009894 170 0.277
epithelial cell migration GO:0010631 148 0.276
canonical wnt signaling pathway GO:0060070 21 0.274
regulation of developmental growth GO:0048638 174 0.268
hemocyte differentiation GO:0042386 38 0.266
regulation of neuron projection development GO:0010975 69 0.262
response to organic cyclic compound GO:0014070 89 0.257
regulation of intracellular protein transport GO:0033157 46 0.256
positive regulation of cell migration GO:0030335 2 0.253
histolysis GO:0007559 102 0.253
negative regulation of developmental process GO:0051093 201 0.252
phosphorylation GO:0016310 294 0.248
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.248
response to endogenous stimulus GO:0009719 119 0.247
regulation of molecular function GO:0065009 217 0.247
negative regulation of catalytic activity GO:0043086 42 0.247
wound healing GO:0042060 75 0.246
cell maturation GO:0048469 144 0.242
germarium derived female germ line cyst formation GO:0030727 42 0.240
salivary gland morphogenesis GO:0007435 145 0.240
regulation of embryonic development GO:0045995 68 0.238
regulation of dendrite morphogenesis GO:0048814 28 0.238
regulation of multi organism process GO:0043900 131 0.237
aging GO:0007568 143 0.235
regulation of actin filament based process GO:0032970 42 0.232
biological adhesion GO:0022610 138 0.232
positive regulation of response to stimulus GO:0048584 323 0.230
regulation of secretion GO:0051046 44 0.230
response to wounding GO:0009611 94 0.230
cardiovascular system development GO:0072358 82 0.228
intracellular signal transduction GO:0035556 300 0.227
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.224
regulation of cytoskeleton organization GO:0051493 89 0.223
axis specification GO:0009798 167 0.218
response to lipid GO:0033993 38 0.217
histone h3 acetylation GO:0043966 11 0.215
positive regulation of phosphorus metabolic process GO:0010562 139 0.215
activation of jun kinase activity GO:0007257 3 0.213
Mouse Rat Worm Fly
immune response GO:0006955 246 0.211
positive regulation of protein modification process GO:0031401 58 0.209
extracellular structure organization GO:0043062 46 0.205
proteolysis GO:0006508 192 0.204
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.202
oocyte development GO:0048599 124 0.201
regulation of hydrolase activity GO:0051336 97 0.199
posttranscriptional regulation of gene expression GO:0010608 145 0.195
regulation of response to external stimulus GO:0032101 115 0.194
regulation of anatomical structure size GO:0090066 163 0.193
cellular response to endogenous stimulus GO:0071495 80 0.193
regulation of cell cycle GO:0051726 291 0.191
cellular response to dna damage stimulus GO:0006974 223 0.191
nucleobase containing compound catabolic process GO:0034655 165 0.188
instar larval development GO:0002168 55 0.187
molting cycle GO:0042303 56 0.187
Fly
multicellular organism growth GO:0035264 46 0.181
regulation of mitotic cell cycle GO:0007346 190 0.178
response to nitrogen compound GO:1901698 90 0.178
immune system development GO:0002520 57 0.176
chitin based cuticle development GO:0040003 49 0.175
regulation of autophagy GO:0010506 62 0.175
positive regulation of protein phosphorylation GO:0001934 34 0.175
positive regulation of cellular component organization GO:0051130 156 0.174
negative regulation of apoptotic signaling pathway GO:2001234 5 0.174
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.172
mitotic cell cycle phase transition GO:0044772 138 0.167
regulation of protein complex assembly GO:0043254 42 0.166
protein targeting GO:0006605 64 0.164
negative regulation of phosphorus metabolic process GO:0010563 45 0.162
regulation of dna metabolic process GO:0051052 34 0.161
organic substance transport GO:0071702 257 0.160
positive regulation of map kinase activity GO:0043406 11 0.159
regulation of phosphorus metabolic process GO:0051174 210 0.159
muscle structure development GO:0061061 224 0.156
meiotic cell cycle GO:0051321 171 0.153
Worm
dendrite development GO:0016358 204 0.152
response to inorganic substance GO:0010035 44 0.151
positive regulation of cell motility GO:2000147 3 0.151
convergent extension GO:0060026 2 0.145
positive regulation of catabolic process GO:0009896 105 0.143
protein modification process GO:0036211 438 0.143
g protein coupled receptor signaling pathway GO:0007186 136 0.141
apoptotic signaling pathway GO:0097190 27 0.141
cell cycle phase transition GO:0044770 140 0.140
regulation of response to wounding GO:1903034 19 0.140
axon guidance GO:0007411 233 0.139
positive regulation of organelle organization GO:0010638 65 0.136
regulation of intracellular transport GO:0032386 64 0.136
hindbrain development GO:0030902 2 0.134
determination of adult lifespan GO:0008340 137 0.134
larval development GO:0002164 104 0.133
regulation of phosphorylation GO:0042325 147 0.133
positive regulation of phosphorylation GO:0042327 87 0.133
localization of cell GO:0051674 257 0.133
neuron fate commitment GO:0048663 50 0.132
imaginal disc derived leg morphogenesis GO:0007480 80 0.132
cellular response to growth factor stimulus GO:0071363 30 0.131
signal transduction by phosphorylation GO:0023014 107 0.130
apoptotic process GO:0006915 159 0.128
Rat
regulation of proteolysis GO:0030162 87 0.128
dormancy process GO:0022611 2 0.127
axonogenesis GO:0007409 290 0.126
regulation of stress activated mapk cascade GO:0032872 41 0.125
eye photoreceptor cell fate commitment GO:0042706 37 0.125
photoreceptor cell fate specification GO:0043704 9 0.124
single organism nuclear import GO:1902593 51 0.124
positive regulation of molecular function GO:0044093 136 0.124
endomembrane system organization GO:0010256 119 0.123
eye photoreceptor cell development GO:0042462 81 0.123
taxis GO:0042330 304 0.123
nucleocytoplasmic transport GO:0006913 72 0.123
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.123
single organism catabolic process GO:0044712 228 0.122
cellular response to abiotic stimulus GO:0071214 58 0.122
positive regulation of phosphate metabolic process GO:0045937 139 0.121
eye morphogenesis GO:0048592 260 0.121
cellular carbohydrate metabolic process GO:0044262 22 0.121
dna replication GO:0006260 48 0.117
unidimensional cell growth GO:0009826 15 0.117
salivary gland development GO:0007431 162 0.115
positive regulation of multi organism process GO:0043902 40 0.115
lipid metabolic process GO:0006629 121 0.113
cell division GO:0051301 248 0.111
positive regulation of signal transduction GO:0009967 223 0.111
protein secretion GO:0009306 45 0.110
response to biotic stimulus GO:0009607 294 0.109
single organism intracellular transport GO:1902582 207 0.109
response to reactive oxygen species GO:0000302 24 0.108
regulation of macroautophagy GO:0016241 15 0.108
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.108
eggshell chorion assembly GO:0007306 66 0.106
regulation of cellular amino acid metabolic process GO:0006521 0 0.105
rho protein signal transduction GO:0007266 14 0.105
positive regulation of neurogenesis GO:0050769 41 0.104
hindgut morphogenesis GO:0007442 58 0.103
jnk cascade GO:0007254 50 0.103
actin polymerization or depolymerization GO:0008154 31 0.101
regulation of cell cycle g1 s phase transition GO:1902806 23 0.101
antimicrobial humoral response GO:0019730 99 0.101
germ band shortening GO:0007390 19 0.100
compound eye retinal cell programmed cell death GO:0046667 23 0.099
response to lipopolysaccharide GO:0032496 4 0.098
photoreceptor cell development GO:0042461 96 0.098
morphogenesis of a branching epithelium GO:0061138 45 0.098
organophosphate metabolic process GO:0019637 195 0.098
regulation of nitric oxide biosynthetic process GO:0045428 1 0.097
macroautophagy GO:0016236 42 0.097
regulation of organ morphogenesis GO:2000027 78 0.096
cellular macromolecular complex assembly GO:0034622 153 0.096
nuclear import GO:0051170 51 0.095
positive regulation of r7 cell differentiation GO:0045678 7 0.095
regulation of cellular response to stress GO:0080135 89 0.094
response to light stimulus GO:0009416 124 0.093
Human
regulation of protein localization to nucleus GO:1900180 29 0.092
synaptic growth at neuromuscular junction GO:0051124 119 0.090
lipid localization GO:0010876 54 0.090
positive regulation of stem cell differentiation GO:2000738 3 0.089
negative regulation of developmental growth GO:0048640 64 0.089
regulation of wnt signaling pathway GO:0030111 68 0.088
secretion by cell GO:0032940 101 0.088
autophagic cell death GO:0048102 83 0.087
regulation of developmental pigmentation GO:0048070 24 0.086
Fly
ameboidal type cell migration GO:0001667 151 0.086
blastoderm segmentation GO:0007350 159 0.085
negative regulation of protein metabolic process GO:0051248 85 0.085
macromolecule catabolic process GO:0009057 161 0.084
regulation of vesicle mediated transport GO:0060627 59 0.084
regulation of protein localization GO:0032880 76 0.083
g1 s transition of mitotic cell cycle GO:0000082 31 0.083
regulation of protein import into nucleus GO:0042306 28 0.082
cellular response to oxygen containing compound GO:1901701 79 0.081
Rat
negative regulation of protein phosphorylation GO:0001933 17 0.080
cellular response to oxidative stress GO:0034599 28 0.078
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.077
positive regulation of nitric oxide biosynthetic process GO:0045429 1 0.076
generation of precursor metabolites and energy GO:0006091 42 0.076
regulation of cell adhesion GO:0030155 27 0.076
chromatin organization GO:0006325 207 0.075
cellular protein catabolic process GO:0044257 83 0.075
regulation of neuroblast proliferation GO:1902692 34 0.075
circulatory system development GO:0072359 82 0.074
regulation of secretion by cell GO:1903530 39 0.074
single organism cellular localization GO:1902580 180 0.073
heart field specification GO:0003128 0 0.073
regulation of stem cell proliferation GO:0072091 40 0.072
response to bacterium GO:0009617 198 0.072
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.071
regulation of cell motility GO:2000145 23 0.071
stem cell development GO:0048864 79 0.070
cellular macromolecule catabolic process GO:0044265 136 0.069
protein localization to organelle GO:0033365 82 0.069
response to temperature stimulus GO:0009266 106 0.069
negative regulation of cell death GO:0060548 81 0.069
negative regulation of cellular protein metabolic process GO:0032269 85 0.069
regulation of transport GO:0051049 181 0.068
response to ketone GO:1901654 34 0.068
regulation of defense response GO:0031347 102 0.067
protein localization GO:0008104 284 0.067
signal transduction in response to dna damage GO:0042770 3 0.067
cell activation GO:0001775 9 0.066
regulation of cellular amine metabolic process GO:0033238 3 0.065
heart development GO:0007507 82 0.065
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.065
positive regulation of mapk cascade GO:0043410 63 0.064
regulation of protein phosphorylation GO:0001932 64 0.064
negative regulation of gene expression epigenetic GO:0045814 77 0.064
response to heat GO:0009408 63 0.063
synapse assembly GO:0007416 143 0.063
cellular response to biotic stimulus GO:0071216 4 0.063
oocyte construction GO:0007308 112 0.062
positive regulation of apoptotic process GO:0043065 47 0.062
Rat
ectodermal digestive tract morphogenesis GO:0048567 7 0.061
small molecule metabolic process GO:0044281 305 0.060
regulation of cell migration GO:0030334 22 0.060
salivary gland cell autophagic cell death GO:0035071 83 0.059
negative regulation of phosphorylation GO:0042326 35 0.059
positive regulation of cytoskeleton organization GO:0051495 21 0.058
positive regulation of cell proliferation GO:0008284 47 0.058
regulation of malpighian tubule diameter GO:0035297 3 0.058
regulation of transferase activity GO:0051338 58 0.058
regulation of imaginal disc growth GO:0045570 26 0.058
positive regulation of cellular protein metabolic process GO:0032270 118 0.058
small gtpase mediated signal transduction GO:0007264 88 0.057
leg disc morphogenesis GO:0007478 80 0.057
regulation of meiosis GO:0040020 3 0.057
regulation of protein serine threonine kinase activity GO:0071900 25 0.057
imaginal disc derived wing hair site selection GO:0035320 4 0.056
regulation of tube size GO:0035150 46 0.056
establishment of protein localization GO:0045184 163 0.055
positive regulation of immune response GO:0050778 63 0.055
i kappab kinase nf kappab signaling GO:0007249 6 0.055
positive regulation of cell development GO:0010720 61 0.054
positive regulation of intracellular transport GO:0032388 42 0.054
imaginal disc growth GO:0007446 37 0.054
peptidyl tyrosine modification GO:0018212 24 0.054
actin filament bundle organization GO:0061572 28 0.054
segmentation GO:0035282 207 0.054
Zebrafish
meiotic nuclear division GO:0007126 151 0.054
Worm
r7 cell fate commitment GO:0007465 12 0.053
rhythmic process GO:0048511 106 0.052
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.052
lipid biosynthetic process GO:0008610 46 0.052
muscle cell differentiation GO:0042692 103 0.052
macromolecular complex assembly GO:0065003 256 0.052
regulation of cell fate specification GO:0042659 27 0.052
regulation of nucleocytoplasmic transport GO:0046822 35 0.052
imaginal disc derived wing hair organization GO:0035317 45 0.051
embryonic organ development GO:0048568 50 0.051
chemotaxis GO:0006935 249 0.051
modification dependent macromolecule catabolic process GO:0043632 79 0.050
single organismal cell cell adhesion GO:0016337 45 0.050
positive regulation of autophagy GO:0010508 21 0.050
negative regulation of transferase activity GO:0051348 18 0.050
positive regulation of transport GO:0051050 92 0.050
actin filament polymerization GO:0030041 27 0.049
epithelium migration GO:0090132 148 0.049
morphogenesis of a branching structure GO:0001763 45 0.049
cell fate determination GO:0001709 91 0.048
positive regulation of catalytic activity GO:0043085 118 0.048
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.048
hemopoiesis GO:0030097 46 0.048
organic cyclic compound catabolic process GO:1901361 168 0.047
negative regulation of stem cell proliferation GO:2000647 30 0.047
intracellular transport GO:0046907 228 0.046
synaptic transmission GO:0007268 288 0.046
protein localization to nucleus GO:0034504 55 0.046
gene silencing GO:0016458 138 0.045
regulation of mitotic spindle checkpoint GO:1903504 1 0.045
positive regulation of locomotion GO:0040017 8 0.044
positive regulation of jnk cascade GO:0046330 16 0.044
defense response GO:0006952 300 0.044
response to mechanical stimulus GO:0009612 28 0.044
protein import GO:0017038 55 0.043
reproductive structure development GO:0048608 74 0.043
genitalia morphogenesis GO:0035112 16 0.043

hep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
familial meningioma DOID:4586 0 0.049
nervous system cancer DOID:3093 0 0.049
central nervous system cancer DOID:3620 0 0.049
cancer DOID:162 0 0.049
disease of cellular proliferation DOID:14566 0 0.049
organ system cancer DOID:0050686 0 0.049
meningioma DOID:3565 0 0.049