Drosophila melanogaster

5 known processes

Ssadh (Dmel_CG4685)

Succinic semialdehyde dehydrogenase

(Aliases: Dmel\CG4685,DmSSADH,anon-WO0118547.428,CG4685)

Ssadh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.085
Human
response to organic substance GO:0010033 284 0.064
acyl coa metabolic process GO:0006637 3 0.058
defense response GO:0006952 300 0.057
response to other organism GO:0051707 293 0.053
cellular response to chemical stimulus GO:0070887 199 0.051
epithelial cell differentiation GO:0030855 322 0.051
response to biotic stimulus GO:0009607 294 0.050
organic hydroxy compound metabolic process GO:1901615 83 0.049
thioester metabolic process GO:0035383 3 0.040
lipid metabolic process GO:0006629 121 0.039
defense response to other organism GO:0098542 225 0.039
nicotinamide nucleotide metabolic process GO:0046496 2 0.038
response to abiotic stimulus GO:0009628 341 0.038
membrane organization GO:0061024 112 0.036
homeostatic process GO:0042592 199 0.035
nucleotide metabolic process GO:0009117 161 0.034
cell migration GO:0016477 238 0.034
epithelial cell development GO:0002064 274 0.033
regionalization GO:0003002 416 0.033
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.033
appendage development GO:0048736 401 0.033
cellular protein modification process GO:0006464 438 0.032
small molecule metabolic process GO:0044281 305 0.032
Human Rat
hormone metabolic process GO:0042445 33 0.032
defense response to bacterium GO:0042742 178 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
oxidoreduction coenzyme metabolic process GO:0006733 2 0.031
response to oxygen containing compound GO:1901700 200 0.031
steroid catabolic process GO:0006706 1 0.031
cell motility GO:0048870 251 0.030
hormone catabolic process GO:0042447 3 0.030
ovarian follicle cell development GO:0030707 248 0.030
gland development GO:0048732 191 0.030
regulation of localization GO:0032879 275 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
Human Rat
cellular macromolecule localization GO:0070727 220 0.029
establishment of localization in cell GO:0051649 402 0.029
protein modification process GO:0036211 438 0.029
single organism biosynthetic process GO:0044711 206 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
organophosphate metabolic process GO:0019637 195 0.028
death GO:0016265 284 0.028
oxidation reduction process GO:0055114 123 0.028
columnar cuboidal epithelial cell development GO:0002066 249 0.028
cellular ketone metabolic process GO:0042180 24 0.028
camera type eye development GO:0043010 4 0.027
response to organonitrogen compound GO:0010243 75 0.027
intracellular transport GO:0046907 228 0.027
localization of cell GO:0051674 257 0.027
positive regulation of biosynthetic process GO:0009891 316 0.026
cell death GO:0008219 279 0.026
response to organophosphorus GO:0046683 2 0.026
oxoacid metabolic process GO:0043436 103 0.026
Human Rat
single organism cellular localization GO:1902580 180 0.026
response to external biotic stimulus GO:0043207 293 0.026
single organism carbohydrate metabolic process GO:0044723 72 0.026
vesicle mediated transport GO:0016192 381 0.026
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
connective tissue development GO:0061448 3 0.025
cellular response to organic substance GO:0071310 132 0.025
carbohydrate metabolic process GO:0005975 82 0.025
pyridine nucleotide metabolic process GO:0019362 2 0.025
single organism membrane organization GO:0044802 93 0.025
response to bacterium GO:0009617 198 0.024
protein localization GO:0008104 284 0.024
programmed cell death GO:0012501 257 0.024
organic acid metabolic process GO:0006082 103 0.024
Human Rat
ameboidal type cell migration GO:0001667 151 0.024
mitochondrion organization GO:0007005 65 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
sulfur compound biosynthetic process GO:0044272 16 0.024
protein complex assembly GO:0006461 200 0.023
Human
cellular amino acid metabolic process GO:0006520 61 0.023
Human
eye development GO:0001654 323 0.023
chemical homeostasis GO:0048878 92 0.022
cell maturation GO:0048469 144 0.022
positive regulation of cell communication GO:0010647 250 0.022
taxis GO:0042330 304 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
phagocytosis GO:0006909 215 0.021
steroid metabolic process GO:0008202 20 0.021
cellular hormone metabolic process GO:0034754 23 0.021
negative regulation of developmental process GO:0051093 201 0.021
macromolecular complex assembly GO:0065003 256 0.021
Human
estrogen metabolic process GO:0008210 1 0.021
positive regulation of lipid metabolic process GO:0045834 4 0.021
intracellular signal transduction GO:0035556 300 0.020
ethanolamine containing compound metabolic process GO:0042439 4 0.020
appendage morphogenesis GO:0035107 397 0.020
cellular response to endogenous stimulus GO:0071495 80 0.020
glycerolipid metabolic process GO:0046486 34 0.020
wing disc morphogenesis GO:0007472 344 0.020
endocytosis GO:0006897 310 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.019
response to lipopolysaccharide GO:0032496 4 0.019
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
salivary gland morphogenesis GO:0007435 145 0.019
cell adhesion GO:0007155 136 0.019
spermatogenesis GO:0007283 200 0.019
regulation of hormone levels GO:0010817 40 0.019
response to endogenous stimulus GO:0009719 119 0.019
tissue migration GO:0090130 155 0.019
cellular amine metabolic process GO:0044106 12 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
catabolic process GO:0009056 409 0.019
Human
single organism behavior GO:0044708 391 0.018
ion transport GO:0006811 145 0.018
purine containing compound metabolic process GO:0072521 155 0.018
positive regulation of signal transduction GO:0009967 223 0.018
alcohol metabolic process GO:0006066 25 0.018
kidney development GO:0001822 3 0.018
developmental growth GO:0048589 280 0.018
protein maturation GO:0051604 71 0.018
androgen metabolic process GO:0008209 1 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
wing disc pattern formation GO:0035222 66 0.018
regulation of transport GO:0051049 181 0.018
amine metabolic process GO:0009308 12 0.018
epithelium migration GO:0090132 148 0.018
response to nutrient levels GO:0031667 114 0.018
response to alcohol GO:0097305 95 0.017
response to nitrogen compound GO:1901698 90 0.017
positive regulation of signaling GO:0023056 243 0.017
single organism catabolic process GO:0044712 228 0.017
Human
regulation of catalytic activity GO:0050790 185 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
central nervous system development GO:0007417 201 0.017
Human
regulation of developmental growth GO:0048638 174 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
positive regulation of response to stimulus GO:0048584 323 0.016
multi organism behavior GO:0051705 175 0.016
cellular protein localization GO:0034613 160 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
protein complex biogenesis GO:0070271 201 0.016
Human
body morphogenesis GO:0010171 2 0.016
cellular homeostasis GO:0019725 80 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
negative regulation of gene expression GO:0010629 387 0.016
proteolysis GO:0006508 192 0.016
negative regulation of signaling GO:0023057 219 0.016
regulation of molecular function GO:0065009 217 0.016
immune system process GO:0002376 347 0.016
organic substance catabolic process GO:1901575 308 0.016
Human
energy derivation by oxidation of organic compounds GO:0015980 32 0.016
establishment of protein localization GO:0045184 163 0.016
epithelial cell migration GO:0010631 148 0.016
pyridine containing compound metabolic process GO:0072524 3 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
negative regulation of cell differentiation GO:0045596 143 0.015
cellular lipid metabolic process GO:0044255 83 0.015
protein transport GO:0015031 155 0.015
regulation of protein metabolic process GO:0051246 256 0.015
forebrain development GO:0030900 2 0.015
negative regulation of cell communication GO:0010648 223 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
response to inorganic substance GO:0010035 44 0.015
negative regulation of signal transduction GO:0009968 206 0.015
regulation of anatomical structure size GO:0090066 163 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
neurological system process GO:0050877 358 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
regulation of nervous system development GO:0051960 248 0.014
lipid localization GO:0010876 54 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
ion homeostasis GO:0050801 55 0.014
immune response GO:0006955 246 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
lateral inhibition GO:0046331 206 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of cell death GO:0010941 173 0.014
ovarian follicle cell migration GO:0007297 121 0.013
response to organic cyclic compound GO:0014070 89 0.013
chromosome segregation GO:0007059 157 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
cellular ion homeostasis GO:0006873 39 0.013
phosphorylation GO:0016310 294 0.013
cellular catabolic process GO:0044248 372 0.013
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
anatomical structure homeostasis GO:0060249 97 0.013
single organism intracellular transport GO:1902582 207 0.013
transmembrane transport GO:0055085 139 0.013
response to radiation GO:0009314 155 0.013
regulation of cellular localization GO:0060341 136 0.013
response to metal ion GO:0010038 23 0.013
nitrogen compound transport GO:0071705 85 0.013
nucleoside metabolic process GO:0009116 127 0.013
innate immune response GO:0045087 144 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.013
transition metal ion homeostasis GO:0055076 17 0.013
negative regulation of response to stimulus GO:0048585 258 0.012
cellular response to hormone stimulus GO:0032870 44 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
cation transport GO:0006812 110 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
response to hormone GO:0009725 45 0.012
anion transport GO:0006820 41 0.012
axonogenesis GO:0007409 290 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
organic substance transport GO:0071702 257 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
aromatic compound catabolic process GO:0019439 166 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
multicellular organismal aging GO:0010259 140 0.012
axon development GO:0061564 297 0.012
maintenance of location GO:0051235 73 0.012
cellular respiration GO:0045333 26 0.012
regulation of programmed cell death GO:0043067 152 0.012
chemotaxis GO:0006935 249 0.012
developmental programmed cell death GO:0010623 138 0.012
protein processing GO:0016485 68 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
biological adhesion GO:0022610 138 0.012
adult locomotory behavior GO:0008344 76 0.012
sulfur compound metabolic process GO:0006790 59 0.012
response to hypoxia GO:0001666 53 0.012
head development GO:0060322 135 0.012
synaptic transmission GO:0007268 288 0.011
actin filament based process GO:0030029 220 0.011
response to oxidative stress GO:0006979 86 0.011
aging GO:0007568 143 0.011
protein targeting GO:0006605 64 0.011
growth GO:0040007 359 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
positive regulation of molecular function GO:0044093 136 0.011
apoptotic process GO:0006915 159 0.011
axon guidance GO:0007411 233 0.011
gland morphogenesis GO:0022612 145 0.011
secretion GO:0046903 109 0.011
mitotic nuclear division GO:0007067 213 0.011
respiratory electron transport chain GO:0022904 11 0.011
intracellular protein transport GO:0006886 104 0.011
regulation of cell cycle GO:0051726 291 0.011
determination of adult lifespan GO:0008340 137 0.011
imaginal disc pattern formation GO:0007447 91 0.011
multi multicellular organism process GO:0044706 123 0.011
nuclear division GO:0000280 332 0.011
embryonic morphogenesis GO:0048598 206 0.011
lipid biosynthetic process GO:0008610 46 0.011
stem cell proliferation GO:0072089 88 0.011
regulation of protein transport GO:0051223 57 0.011
positive regulation of cell motility GO:2000147 3 0.011
response to decreased oxygen levels GO:0036293 58 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
metal ion homeostasis GO:0055065 44 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
positive regulation of developmental process GO:0051094 143 0.011
cellular response to nitrogen compound GO:1901699 51 0.010
brain development GO:0007420 120 0.010
histolysis GO:0007559 102 0.010
positive regulation of gene expression GO:0010628 290 0.010
response to oxygen levels GO:0070482 59 0.010
peripheral nervous system development GO:0007422 52 0.010
cytoplasmic transport GO:0016482 130 0.010
regulation of protein localization GO:0032880 76 0.010
positive regulation of cell migration GO:0030335 2 0.010
organophosphate biosynthetic process GO:0090407 46 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010

Ssadh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.013
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.010