Drosophila melanogaster

112 known processes

Sep2 (Dmel_CG4173)

Septin-2

(Aliases: sep2,Dmel\CG4173,CG4173)

Sep2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biosynthetic process GO:0009890 277 0.753
dna conformation change GO:0071103 105 0.537
regulation of multicellular organismal development GO:2000026 414 0.481
positive regulation of biosynthetic process GO:0009891 316 0.417
positive regulation of cellular component organization GO:0051130 156 0.400
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.377
positive regulation of rna metabolic process GO:0051254 271 0.353
ovarian nurse cell to oocyte transport GO:0007300 27 0.334
positive regulation of nervous system development GO:0051962 69 0.308
cellular catabolic process GO:0044248 372 0.295
negative regulation of cellular metabolic process GO:0031324 382 0.290
asymmetric cell division GO:0008356 37 0.271
response to heat GO:0009408 63 0.271
negative regulation of gene expression GO:0010629 387 0.268
gene silencing GO:0016458 138 0.249
organelle assembly GO:0070925 198 0.244
regulation of gene expression epigenetic GO:0040029 128 0.243
dorsal ventral pattern formation GO:0009953 133 0.239
nuclear division GO:0000280 332 0.236
cell migration GO:0016477 238 0.235
meiotic cell cycle process GO:1903046 132 0.233
chromosome segregation GO:0007059 157 0.222
organelle fission GO:0048285 340 0.219
male gamete generation GO:0048232 201 0.213
immune system process GO:0002376 347 0.210
negative regulation of cellular biosynthetic process GO:0031327 277 0.208
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.207
cell proliferation GO:0008283 299 0.204
positive regulation of macromolecule metabolic process GO:0010604 405 0.204
regulation of cell proliferation GO:0042127 163 0.193
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.192
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.192
negative regulation of rna biosynthetic process GO:1902679 240 0.191
negative regulation of transcription dna templated GO:0045892 237 0.186
spermatogenesis GO:0007283 200 0.180
chromatin silencing GO:0006342 76 0.178
spermatid differentiation GO:0048515 114 0.174
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.173
stem cell division GO:0017145 69 0.172
muscle structure development GO:0061061 224 0.171
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.157
female meiotic division GO:0007143 70 0.148
chromatin assembly or disassembly GO:0006333 52 0.148
regulation of catabolic process GO:0009894 170 0.146
meiotic cell cycle GO:0051321 171 0.146
regulation of anatomical structure morphogenesis GO:0022603 242 0.146
negative regulation of multicellular organismal process GO:0051241 142 0.142
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.135
spermatid development GO:0007286 98 0.130
cytoskeleton dependent cytokinesis GO:0061640 81 0.130
nucleobase containing compound catabolic process GO:0034655 165 0.123
chromatin remodeling GO:0006338 72 0.122
posttranscriptional regulation of gene expression GO:0010608 145 0.121
body morphogenesis GO:0010171 2 0.115
transcription from rna polymerase ii promoter GO:0006366 368 0.115
cell division GO:0051301 248 0.113
regulation of cellular catabolic process GO:0031329 157 0.113
chromosome separation GO:0051304 42 0.110
negative regulation of chromosome segregation GO:0051985 14 0.108
cell cycle checkpoint GO:0000075 95 0.106
negative regulation of rna metabolic process GO:0051253 251 0.105
regulation of cell differentiation GO:0045595 302 0.104
positive regulation of protein transport GO:0051222 37 0.102
ubiquitin dependent protein catabolic process GO:0006511 78 0.099
cellular macromolecule catabolic process GO:0044265 136 0.099
negative regulation of developmental process GO:0051093 201 0.095
homeostatic process GO:0042592 199 0.094
cellular protein catabolic process GO:0044257 83 0.093
developmental growth GO:0048589 280 0.092
positive regulation of transport GO:0051050 92 0.092
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.092
regulation of intracellular protein transport GO:0033157 46 0.091
cytokinesis GO:0000910 90 0.088
response to temperature stimulus GO:0009266 106 0.087
proteasomal protein catabolic process GO:0010498 59 0.086
positive regulation of transcription dna templated GO:0045893 266 0.086
meiotic nuclear division GO:0007126 151 0.086
actin cytoskeleton organization GO:0030036 206 0.085
nucleotide metabolic process GO:0009117 161 0.083
intracellular transport GO:0046907 228 0.083
establishment of localization in cell GO:0051649 402 0.083
purine containing compound metabolic process GO:0072521 155 0.082
macromolecule catabolic process GO:0009057 161 0.080
alternative mrna splicing via spliceosome GO:0000380 60 0.080
maintenance of protein location GO:0045185 28 0.079
cell cycle phase transition GO:0044770 140 0.077
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.077
neurological system process GO:0050877 358 0.076
mitotic spindle organization GO:0007052 220 0.076
negative regulation of nucleic acid templated transcription GO:1903507 240 0.075
negative regulation of protein metabolic process GO:0051248 85 0.073
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.072
positive regulation of nucleic acid templated transcription GO:1903508 266 0.072
determination of adult lifespan GO:0008340 137 0.071
cellular nitrogen compound catabolic process GO:0044270 165 0.070
organonitrogen compound metabolic process GO:1901564 318 0.070
wnt signaling pathway GO:0016055 98 0.070
negative regulation of cell cycle phase transition GO:1901988 103 0.070
carbohydrate derivative metabolic process GO:1901135 217 0.069
regulation of nervous system development GO:0051960 248 0.068
mitotic nuclear division GO:0007067 213 0.067
gene silencing by mirna GO:0035195 22 0.067
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.066
regulation of intracellular transport GO:0032386 64 0.066
actomyosin structure organization GO:0031032 56 0.065
synapse assembly GO:0007416 143 0.064
single organism behavior GO:0044708 391 0.064
cellular amino acid metabolic process GO:0006520 61 0.062
growth GO:0040007 359 0.060
ribonucleotide metabolic process GO:0009259 145 0.059
positive regulation of rna biosynthetic process GO:1902680 266 0.057
aromatic compound catabolic process GO:0019439 166 0.056
golgi vesicle transport GO:0048193 27 0.056
regulation of mitotic sister chromatid segregation GO:0033047 28 0.056
axis specification GO:0009798 167 0.055
purine containing compound catabolic process GO:0072523 112 0.055
posttranscriptional gene silencing GO:0016441 46 0.054
organic cyclic compound catabolic process GO:1901361 168 0.054
oocyte construction GO:0007308 112 0.054
regulation of wnt signaling pathway GO:0030111 68 0.054
protein acetylation GO:0006473 39 0.053
regulation of chromosome segregation GO:0051983 32 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
mitotic cell cycle phase transition GO:0044772 138 0.052
regulation of cellular protein catabolic process GO:1903362 44 0.051
glycosyl compound catabolic process GO:1901658 112 0.050
reproductive behavior GO:0019098 122 0.050
modification dependent macromolecule catabolic process GO:0043632 79 0.050
multi multicellular organism process GO:0044706 123 0.048
regulation of nuclear division GO:0051783 58 0.048
cell motility GO:0048870 251 0.048
purine ribonucleotide catabolic process GO:0009154 109 0.048
nucleoside triphosphate catabolic process GO:0009143 108 0.047
modification dependent protein catabolic process GO:0019941 78 0.047
oocyte axis specification GO:0007309 108 0.045
mitotic sister chromatid separation GO:0051306 30 0.044
nucleobase containing small molecule metabolic process GO:0055086 174 0.044
regulation of sister chromatid segregation GO:0033045 28 0.044
guanosine containing compound catabolic process GO:1901069 74 0.044
regulation of cell cycle phase transition GO:1901987 130 0.043
internal protein amino acid acetylation GO:0006475 38 0.043
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.043
protein complex assembly GO:0006461 200 0.043
peptide metabolic process GO:0006518 80 0.043
dendrite development GO:0016358 204 0.042
regulation of proteasomal protein catabolic process GO:0061136 39 0.042
negative regulation of signal transduction GO:0009968 206 0.042
regulation of meiosis GO:0040020 3 0.041
cellular amine metabolic process GO:0044106 12 0.041
regulation of multi organism process GO:0043900 131 0.041
response to other organism GO:0051707 293 0.041
cell growth GO:0016049 108 0.041
tissue morphogenesis GO:0048729 297 0.040
neural precursor cell proliferation GO:0061351 75 0.040
regulation of organelle organization GO:0033043 196 0.040
dendrite morphogenesis GO:0048813 199 0.040
positive regulation of gene expression GO:0010628 290 0.040
neuron projection guidance GO:0097485 241 0.039
regulation of translation GO:0006417 56 0.039
nucleoside triphosphate metabolic process GO:0009141 120 0.039
eye development GO:0001654 323 0.038
peptidyl lysine acetylation GO:0018394 39 0.038
regulation of transport GO:0051049 181 0.038
protein exit from endoplasmic reticulum GO:0032527 5 0.038
positive regulation of developmental process GO:0051094 143 0.037
single organism intracellular transport GO:1902582 207 0.037
positive regulation of signal transduction GO:0009967 223 0.037
convergent extension GO:0060026 2 0.037
ribonucleoside catabolic process GO:0042454 112 0.036
negative regulation of sister chromatid segregation GO:0033046 13 0.036
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.036
negative regulation of cell cycle process GO:0010948 109 0.035
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
intracellular signal transduction GO:0035556 300 0.035
spindle checkpoint GO:0031577 11 0.035
organic substance catabolic process GO:1901575 308 0.035
protein maturation GO:0051604 71 0.034
regulation of cellular component biogenesis GO:0044087 201 0.034
karyosome formation GO:0030717 22 0.034
eye morphogenesis GO:0048592 260 0.034
oocyte differentiation GO:0009994 145 0.033
negative regulation of protein polymerization GO:0032272 7 0.033
negative regulation of chromosome organization GO:2001251 19 0.032
embryonic morphogenesis GO:0048598 206 0.032
mitotic cytokinesis GO:0000281 50 0.032
retinal cell programmed cell death GO:0046666 25 0.032
guanosine containing compound metabolic process GO:1901068 74 0.032
retina development in camera type eye GO:0060041 4 0.031
organic acid metabolic process GO:0006082 103 0.031
rna processing GO:0006396 147 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
negative regulation of translation GO:0017148 28 0.030
cellular macromolecule localization GO:0070727 220 0.030
mitotic sister chromatid segregation GO:0000070 87 0.030
negative regulation of catabolic process GO:0009895 36 0.030
peptidyl lysine modification GO:0018205 57 0.030
positive regulation of cell development GO:0010720 61 0.029
cell junction organization GO:0034330 57 0.029
regulation of production of molecular mediator of immune response GO:0002700 44 0.029
spindle organization GO:0007051 253 0.028
regulation of localization GO:0032879 275 0.027
regulation of organ morphogenesis GO:2000027 78 0.027
gastrulation with mouth forming first GO:0001703 36 0.027
regulation of mitosis GO:0007088 56 0.027
cytoplasmic transport GO:0016482 130 0.027
dorsal ventral axis specification GO:0009950 66 0.027
digestive tract morphogenesis GO:0048546 127 0.027
post embryonic appendage morphogenesis GO:0035120 385 0.027
regulation of cell development GO:0060284 215 0.026
small molecule metabolic process GO:0044281 305 0.026
death GO:0016265 284 0.026
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
negative regulation of cell differentiation GO:0045596 143 0.026
macromolecular complex assembly GO:0065003 256 0.026
digestive system development GO:0055123 149 0.026
regulation of proteolysis GO:0030162 87 0.026
chromatin modification GO:0016568 147 0.026
tube development GO:0035295 244 0.026
purine nucleoside triphosphate metabolic process GO:0009144 119 0.025
actin filament based process GO:0030029 220 0.025
head involution GO:0008258 35 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.024
positive regulation of molecular function GO:0044093 136 0.024
negative regulation of cell cycle GO:0045786 116 0.024
establishment of planar polarity GO:0001736 87 0.024
chromatin organization GO:0006325 207 0.023
protein catabolic process GO:0030163 101 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
nucleoside catabolic process GO:0009164 112 0.023
respiratory system development GO:0060541 213 0.023
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.023
gene silencing by rna GO:0031047 57 0.023
negative regulation of response to stimulus GO:0048585 258 0.023
genitalia development GO:0048806 26 0.022
negative regulation of cell division GO:0051782 17 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.022
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.021
multi organism reproductive behavior GO:0044705 121 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
cell maturation GO:0048469 144 0.021
mrna metabolic process GO:0016071 124 0.021
regulation of mitotic sister chromatid separation GO:0010965 28 0.021
regulation of immune system process GO:0002682 176 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
regulation of developmental growth GO:0048638 174 0.020
positive regulation of intracellular transport GO:0032388 42 0.020
internal peptidyl lysine acetylation GO:0018393 38 0.020
posttranscriptional gene silencing by rna GO:0035194 45 0.020
morphogenesis of embryonic epithelium GO:0016331 94 0.020
positive regulation of hydrolase activity GO:0051345 78 0.019
chemotaxis GO:0006935 249 0.019
digestive tract development GO:0048565 149 0.019
chromatin assembly GO:0031497 48 0.019
development of primary sexual characteristics GO:0045137 50 0.019
positive regulation of intracellular protein transport GO:0090316 30 0.019
positive regulation of signaling GO:0023056 243 0.019
maintenance of location in cell GO:0051651 28 0.019
positive regulation of catabolic process GO:0009896 105 0.019
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.019
head development GO:0060322 135 0.019
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.018
regulation of protein localization GO:0032880 76 0.018
multicellular organismal aging GO:0010259 140 0.018
pole plasm assembly GO:0007315 61 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
regulation of phosphatase activity GO:0010921 3 0.018
organophosphate metabolic process GO:0019637 195 0.018
ribonucleoprotein complex assembly GO:0022618 23 0.018
heterocycle catabolic process GO:0046700 166 0.018
dna metabolic process GO:0006259 227 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
asymmetric neuroblast division GO:0055059 33 0.017
developmental maturation GO:0021700 172 0.017
nucleosome organization GO:0034728 59 0.017
regulation of mrna splicing via spliceosome GO:0048024 64 0.017
rna localization GO:0006403 115 0.017
metaphase anaphase transition of cell cycle GO:0044784 28 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
taxis GO:0042330 304 0.017
cell junction assembly GO:0034329 42 0.017
open tracheal system development GO:0007424 204 0.017
multicellular organismal homeostasis GO:0048871 41 0.016
translation GO:0006412 69 0.016
multi organism behavior GO:0051705 175 0.016
oocyte dorsal ventral axis specification GO:0007310 34 0.016
nucleoside metabolic process GO:0009116 127 0.016
regulation of cell division GO:0051302 72 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
regulation of cellular response to stress GO:0080135 89 0.016
maintenance of protein location in cell GO:0032507 26 0.016
protein complex biogenesis GO:0070271 201 0.016
anatomical structure homeostasis GO:0060249 97 0.016
tissue death GO:0016271 102 0.016
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.016
cellular response to organic substance GO:0071310 132 0.016
negative regulation of protein catabolic process GO:0042177 17 0.015
negative regulation of cell communication GO:0010648 223 0.015
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.015
regulation of protein maturation GO:1903317 32 0.015
positive regulation of cell communication GO:0010647 250 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
negative regulation of phosphatase activity GO:0010923 3 0.015
cellular lipid metabolic process GO:0044255 83 0.015
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
regionalization GO:0003002 416 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
carbohydrate derivative biosynthetic process GO:1901137 85 0.014
sensory organ morphogenesis GO:0090596 260 0.014
asymmetric stem cell division GO:0098722 49 0.014
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.014
regulation of protein localization to nucleus GO:1900180 29 0.014
developmental programmed cell death GO:0010623 138 0.014
organic substance transport GO:0071702 257 0.014
oviposition GO:0018991 19 0.014
epithelial cell development GO:0002064 274 0.014
tissue homeostasis GO:0001894 36 0.014
catabolic process GO:0009056 409 0.014
nucleotide catabolic process GO:0009166 109 0.013
pronuclear migration GO:0035046 4 0.013
amine metabolic process GO:0009308 12 0.013
response to abiotic stimulus GO:0009628 341 0.013
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.013
nuclear migration GO:0007097 20 0.013
striated muscle cell development GO:0055002 50 0.013
negative regulation of nervous system development GO:0051961 92 0.013
compound eye retinal cell programmed cell death GO:0046667 23 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
regulation of synapse assembly GO:0051963 94 0.013
protein heterooligomerization GO:0051291 4 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
cell recognition GO:0008037 102 0.013
regulation of canonical wnt signaling pathway GO:0060828 15 0.013
nucleus organization GO:0006997 45 0.013
camera type eye development GO:0043010 4 0.013
ncrna metabolic process GO:0034660 43 0.013
regulation of response to stress GO:0080134 200 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
chromosome organization GO:0051276 360 0.012
mitotic spindle checkpoint GO:0071174 11 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
regulation of cellular localization GO:0060341 136 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of anatomical structure size GO:0090066 163 0.012
regulation of molecular function GO:0065009 217 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
stem cell proliferation GO:0072089 88 0.012
salivary gland histolysis GO:0035070 88 0.012
axonogenesis GO:0007409 290 0.012
positive regulation of synapse assembly GO:0051965 29 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
proteolysis GO:0006508 192 0.011
response to inorganic substance GO:0010035 44 0.011
establishment of mitotic spindle localization GO:0040001 17 0.011
neuroblast proliferation GO:0007405 74 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
organophosphate catabolic process GO:0046434 112 0.011
cytoplasmic mrna processing body assembly GO:0033962 10 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
meiotic chromosome segregation GO:0045132 59 0.011
negative regulation of protein maturation GO:1903318 31 0.011
ameboidal type cell migration GO:0001667 151 0.011
regulation of cell cycle process GO:0010564 181 0.011
vesicle mediated transport GO:0016192 381 0.011
regulation of protein targeting GO:1903533 29 0.011
positive regulation of organelle organization GO:0010638 65 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
dna packaging GO:0006323 91 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
histolysis GO:0007559 102 0.011
ncrna processing GO:0034470 30 0.011
regulation of neurogenesis GO:0050767 158 0.011
intracellular protein transport GO:0006886 104 0.011
exocrine system development GO:0035272 162 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
central nervous system development GO:0007417 201 0.010
regulation of protein transport GO:0051223 57 0.010
single organism catabolic process GO:0044712 228 0.010
canonical wnt signaling pathway GO:0060070 21 0.010
axon guidance GO:0007411 233 0.010
learning or memory GO:0007611 141 0.010
cell fate specification GO:0001708 71 0.010
protein processing GO:0016485 68 0.010
secretion GO:0046903 109 0.010
muscle cell differentiation GO:0042692 103 0.010
gland development GO:0048732 191 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010
positive regulation of secretion by cell GO:1903532 20 0.010

Sep2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.030
central nervous system disease DOID:331 0 0.030
disease of anatomical entity DOID:7 0 0.030
neurodegenerative disease DOID:1289 0 0.030
nervous system disease DOID:863 0 0.030
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.015