Drosophila melanogaster

176 known processes

par-6 (Dmel_CG5884)

CG5884 gene product from transcript CG5884-RA

(Aliases: dmPar-6,Par,dPar-6,Dmpar6,dPAR-6,PAR6,Par6,Dmel\CG5884,par,Dm-Par-6,DmPar-6,DPar6,DPar-6,CG5884,DmPAR-6,PAR-6,par6,DmPar6,Par-6)

par-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
border follicle cell migration GO:0007298 113 1.000
ovarian follicle cell migration GO:0007297 121 1.000
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.997
oocyte development GO:0048599 124 0.997
pole plasm mrna localization GO:0019094 49 0.997
oocyte axis specification GO:0007309 108 0.997
pole plasm oskar mrna localization GO:0045451 46 0.997
epithelial cell development GO:0002064 274 0.995
oocyte construction GO:0007308 112 0.994
pole plasm rna localization GO:0007316 52 0.992
epithelial cell differentiation GO:0030855 322 0.990
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.986
cellular macromolecule localization GO:0070727 220 0.983
establishment of localization in cell GO:0051649 402 0.981
Worm
blastoderm segmentation GO:0007350 159 0.980
ameboidal type cell migration GO:0001667 151 0.980
oocyte differentiation GO:0009994 145 0.974
oocyte microtubule cytoskeleton organization GO:0016325 35 0.971
epithelium migration GO:0090132 148 0.971
regulation of cell differentiation GO:0045595 302 0.968
Zebrafish
female germ line cyst formation GO:0048135 42 0.967
germ line cyst formation GO:0048134 44 0.962
oocyte anterior posterior axis specification GO:0007314 72 0.960
pole plasm assembly GO:0007315 61 0.952
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.951
ovarian follicle cell development GO:0030707 248 0.937
cytoplasm organization GO:0007028 64 0.935
developmental maturation GO:0021700 172 0.932
germarium derived female germ line cyst formation GO:0030727 42 0.903
rna localization GO:0006403 115 0.901
anterior posterior axis specification embryo GO:0008595 103 0.889
spindle organization GO:0007051 253 0.887
establishment or maintenance of cell polarity GO:0007163 167 0.874
cell migration GO:0016477 238 0.864
columnar cuboidal epithelial cell development GO:0002066 249 0.862
embryonic axis specification GO:0000578 107 0.855
localization of cell GO:0051674 257 0.852
germarium derived oocyte fate determination GO:0007294 26 0.852
anterior posterior axis specification GO:0009948 109 0.850
Worm
epithelial cell migration GO:0010631 148 0.850
mitotic spindle organization GO:0007052 220 0.839
stem cell division GO:0017145 69 0.837
macromolecular complex assembly GO:0065003 256 0.806
Human
cell motility GO:0048870 251 0.788
cell maturation GO:0048469 144 0.780
tissue migration GO:0090130 155 0.768
negative regulation of developmental process GO:0051093 201 0.765
single organism cellular localization GO:1902580 180 0.764
Worm
anterior posterior pattern specification GO:0009952 136 0.756
Worm
maternal determination of anterior posterior axis embryo GO:0008358 74 0.749
tripartite regional subdivision GO:0007351 103 0.713
neurological system process GO:0050877 358 0.712
establishment of spindle localization GO:0051293 22 0.701
Worm
tube development GO:0035295 244 0.696
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.695
protein complex assembly GO:0006461 200 0.676
Human
intracellular mrna localization GO:0008298 66 0.673
embryonic development via the syncytial blastoderm GO:0001700 148 0.640
regulation of multicellular organismal development GO:2000026 414 0.637
Zebrafish
regulation of nervous system development GO:0051960 248 0.635
Zebrafish
tissue morphogenesis GO:0048729 297 0.629
organic substance transport GO:0071702 257 0.625
regulation of cellular component biogenesis GO:0044087 201 0.617
notch signaling pathway GO:0007219 120 0.606
embryonic pattern specification GO:0009880 174 0.592
regulation of developmental growth GO:0048638 174 0.581
Zebrafish Worm
cell proliferation GO:0008283 299 0.565
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.553
developmental growth GO:0048589 280 0.546
Zebrafish Worm
axis specification GO:0009798 167 0.531
Worm
oocyte fate determination GO:0030716 27 0.525
cytokinesis GO:0000910 90 0.523
protein complex biogenesis GO:0070271 201 0.496
Human
germarium derived egg chamber formation GO:0007293 101 0.487
segmentation GO:0035282 207 0.485
morphogenesis of an epithelium GO:0002009 276 0.483
small molecule metabolic process GO:0044281 305 0.483
cell projection assembly GO:0030031 94 0.480
immune response GO:0006955 246 0.468
cytoskeleton dependent cytokinesis GO:0061640 81 0.467
neuronal stem cell division GO:0036445 35 0.463
regulation of protein polymerization GO:0032271 28 0.457
regulation of cell morphogenesis GO:0022604 163 0.453
regulation of actin filament polymerization GO:0030833 25 0.438
immune effector process GO:0002252 98 0.431
regulation of actin filament length GO:0030832 27 0.423
establishment of spindle orientation GO:0051294 18 0.415
cellular ketone metabolic process GO:0042180 24 0.403
regulation of cell death GO:0010941 173 0.381
enzyme linked receptor protein signaling pathway GO:0007167 179 0.381
growth GO:0040007 359 0.376
Zebrafish Worm
organelle assembly GO:0070925 198 0.375
chaeta development GO:0022416 97 0.361
organic substance catabolic process GO:1901575 308 0.354
transmembrane transport GO:0055085 139 0.342
regulation of cell development GO:0060284 215 0.336
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 242 0.330
open tracheal system development GO:0007424 204 0.326
germarium derived oocyte differentiation GO:0030706 29 0.323
regulation of cellular amino acid metabolic process GO:0006521 0 0.322
establishment of cell polarity GO:0030010 40 0.321
carboxylic acid metabolic process GO:0019752 92 0.318
positive regulation of rna metabolic process GO:0051254 271 0.315
asymmetric neuroblast division GO:0055059 33 0.310
regulation of actin filament based process GO:0032970 42 0.306
axonogenesis GO:0007409 290 0.278
Zebrafish
nucleocytoplasmic transport GO:0006913 72 0.278
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.277
synapse assembly GO:0007416 143 0.276
stem cell development GO:0048864 79 0.273
negative regulation of signaling GO:0023057 219 0.267
positive regulation of cell projection organization GO:0031346 29 0.258
membrane organization GO:0061024 112 0.257
negative regulation of cytoskeleton organization GO:0051494 30 0.256
actin cytoskeleton organization GO:0030036 206 0.254
cellular macromolecular complex assembly GO:0034622 153 0.251
oxoacid metabolic process GO:0043436 103 0.249
endosomal vesicle fusion GO:0034058 4 0.248
regulation of actin cytoskeleton organization GO:0032956 42 0.248
single organism intracellular transport GO:1902582 207 0.247
adult locomotory behavior GO:0008344 76 0.242
regulation of actin polymerization or depolymerization GO:0008064 27 0.239
stem cell proliferation GO:0072089 88 0.239
cytoplasmic transport GO:0016482 130 0.238
organonitrogen compound metabolic process GO:1901564 318 0.237
single organism membrane organization GO:0044802 93 0.231
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.230
regulation of cell projection assembly GO:0060491 30 0.228
regulation of cytoskeleton organization GO:0051493 89 0.209
asymmetric cell division GO:0008356 37 0.206
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.197
cellular protein complex assembly GO:0043623 71 0.194
cellular response to chemical stimulus GO:0070887 199 0.190
defense response GO:0006952 300 0.186
amine metabolic process GO:0009308 12 0.186
membrane fusion GO:0061025 42 0.185
morphogenesis of embryonic epithelium GO:0016331 94 0.182
Zebrafish
establishment of protein localization GO:0045184 163 0.181
actin filament polymerization GO:0030041 27 0.179
actin polymerization or depolymerization GO:0008154 31 0.179
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.178
synapse organization GO:0050808 196 0.176
nuclear transport GO:0051169 72 0.176
regulation of cellular response to growth factor stimulus GO:0090287 13 0.175
regulation of notch signaling pathway GO:0008593 100 0.173
stem cell differentiation GO:0048863 117 0.173
embryo development ending in birth or egg hatching GO:0009792 152 0.167
Zebrafish Worm
organic acid metabolic process GO:0006082 103 0.167
regulation of protein metabolic process GO:0051246 256 0.167
neuroblast division GO:0055057 35 0.166
branching involved in open tracheal system development GO:0060446 45 0.165
positive regulation of signaling GO:0023056 243 0.163
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.161
negative regulation of biosynthetic process GO:0009890 277 0.158
positive regulation of actin filament polymerization GO:0030838 11 0.155
cellular macromolecule catabolic process GO:0044265 136 0.151
negative regulation of cell differentiation GO:0045596 143 0.148
positive regulation of cytoskeleton organization GO:0051495 21 0.144
ribonucleoprotein complex subunit organization GO:0071826 28 0.144
regulation of protein complex assembly GO:0043254 42 0.142
negative regulation of response to stimulus GO:0048585 258 0.139
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.138
regulation of pole plasm oskar mrna localization GO:0007317 27 0.137
negative regulation of nervous system development GO:0051961 92 0.135
intracellular transport GO:0046907 228 0.134
cellular response to growth factor stimulus GO:0071363 30 0.132
regulation of filopodium assembly GO:0051489 24 0.131
cellular nitrogen compound catabolic process GO:0044270 165 0.131
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.130
morphogenesis of follicular epithelium GO:0016333 36 0.129
establishment of glial blood brain barrier GO:0060857 14 0.129
morphogenesis of a branching epithelium GO:0061138 45 0.128
regulation of proteolysis GO:0030162 87 0.126
cellular protein localization GO:0034613 160 0.126
cellular amino acid metabolic process GO:0006520 61 0.125
regulation of endocytosis GO:0030100 37 0.119
asymmetric stem cell division GO:0098722 49 0.117
negative regulation of cell death GO:0060548 81 0.116
filopodium assembly GO:0046847 33 0.113
transcription from rna polymerase ii promoter GO:0006366 368 0.113
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.113
cortical actin cytoskeleton organization GO:0030866 24 0.111
protein transport GO:0015031 155 0.110
positive regulation of nucleic acid templated transcription GO:1903508 266 0.110
regulation of immune response GO:0050776 118 0.109
larval development GO:0002164 104 0.108
Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.108
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.108
single organism cell adhesion GO:0098602 47 0.108
negative regulation of cell communication GO:0010648 223 0.106
branching morphogenesis of an epithelial tube GO:0048754 45 0.106
cell division GO:0051301 248 0.103
regulation of cellular ketone metabolic process GO:0010565 3 0.102
compound eye development GO:0048749 307 0.101
hindbrain development GO:0030902 2 0.100
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.100
epithelial tube morphogenesis GO:0060562 88 0.099
regionalization GO:0003002 416 0.099
Worm
humoral immune response GO:0006959 117 0.098
catabolic process GO:0009056 409 0.098
cellular catabolic process GO:0044248 372 0.096
establishment of mitotic spindle localization GO:0040001 17 0.096
Worm
positive regulation of response to stimulus GO:0048584 323 0.096
establishment of mitotic spindle orientation GO:0000132 13 0.095
negative regulation of signal transduction GO:0009968 206 0.094
cellular response to carbon dioxide GO:0071244 2 0.094
regulation of cellular amine metabolic process GO:0033238 3 0.093
negative regulation of cellular biosynthetic process GO:0031327 277 0.091
negative regulation of programmed cell death GO:0043069 72 0.090
stem cell maintenance GO:0019827 67 0.090
chromosome segregation GO:0007059 157 0.088
single organism membrane fusion GO:0044801 42 0.088
regulation of protein complex disassembly GO:0043244 29 0.088
regulation of dendrite morphogenesis GO:0048814 28 0.087
positive regulation of cell communication GO:0010647 250 0.087
protein import GO:0017038 55 0.086
cell type specific apoptotic process GO:0097285 38 0.086
response to carbon dioxide GO:0010037 4 0.084
renal tubule development GO:0061326 64 0.084
endocytosis GO:0006897 310 0.084
positive regulation of nervous system development GO:0051962 69 0.084
positive regulation of cellular component biogenesis GO:0044089 80 0.084
tube morphogenesis GO:0035239 191 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.082
cellular amine metabolic process GO:0044106 12 0.082
neuroblast proliferation GO:0007405 74 0.081
positive regulation of signal transduction GO:0009967 223 0.081
regulation of cell cell adhesion GO:0022407 21 0.080
positive regulation of growth GO:0045927 75 0.077
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.076
positive regulation of cellular component organization GO:0051130 156 0.074
pronuclear migration GO:0035046 4 0.074
organophosphate metabolic process GO:0019637 195 0.072
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.072
negative regulation of cell cycle phase transition GO:1901988 103 0.072
negative regulation of neurogenesis GO:0050768 53 0.072
protein polymerization GO:0051258 42 0.071
apical constriction GO:0003383 18 0.071
peptidyl amino acid modification GO:0018193 105 0.071
regulation of mitotic cell cycle GO:0007346 190 0.070
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.070
macromolecule catabolic process GO:0009057 161 0.070
protein acylation GO:0043543 42 0.069
protein targeting to nucleus GO:0044744 51 0.069
biological adhesion GO:0022610 138 0.069
regulation of neuron differentiation GO:0045664 103 0.069
Zebrafish
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.069
positive regulation of transcription dna templated GO:0045893 266 0.067
response to nutrient levels GO:0031667 114 0.065
negative regulation of rna metabolic process GO:0051253 251 0.063
regulation of multi organism process GO:0043900 131 0.063
mapk cascade GO:0000165 107 0.063
nucleobase containing compound catabolic process GO:0034655 165 0.062
protein targeting GO:0006605 64 0.061
actin filament organization GO:0007015 126 0.060
appendage morphogenesis GO:0035107 397 0.059
purine nucleoside metabolic process GO:0042278 127 0.058
photoreceptor cell development GO:0042461 96 0.058
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.058
regulation of protein depolymerization GO:1901879 27 0.058
neuromuscular junction development GO:0007528 149 0.057
establishment of blood brain barrier GO:0060856 16 0.057
mitotic cell cycle checkpoint GO:0007093 88 0.057
single organismal cell cell adhesion GO:0016337 45 0.057
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.056
somatic stem cell division GO:0048103 37 0.056
regulation of hemocyte proliferation GO:0035206 37 0.056
maintenance of cell polarity GO:0030011 18 0.056
respiratory system development GO:0060541 213 0.055
regulation of dendrite development GO:0050773 37 0.055
taxis GO:0042330 304 0.054
instar larval development GO:0002168 55 0.054
actin filament based process GO:0030029 220 0.052
multicellular organism growth GO:0035264 46 0.052
Worm
regulation of reproductive process GO:2000241 54 0.052
positive regulation of axonogenesis GO:0050772 2 0.052
receptor mediated endocytosis GO:0006898 21 0.052
Worm
regulation of synaptic transmission GO:0050804 69 0.051
positive regulation of notch signaling pathway GO:0045747 34 0.051
intracellular signal transduction GO:0035556 300 0.050
response to other organism GO:0051707 293 0.049
regulation of lamellipodium organization GO:1902743 15 0.049
response to radiation GO:0009314 155 0.049
photoreceptor cell differentiation GO:0046530 170 0.048
mrna metabolic process GO:0016071 124 0.048
trachea morphogenesis GO:0060439 22 0.048
negative regulation of multicellular organismal process GO:0051241 142 0.048
organic cyclic compound catabolic process GO:1901361 168 0.047
response to biotic stimulus GO:0009607 294 0.047
detection of stimulus GO:0051606 156 0.047
nitrogen compound transport GO:0071705 85 0.046
regulation of immune effector process GO:0002697 52 0.046
heterocycle catabolic process GO:0046700 166 0.044
small gtpase mediated signal transduction GO:0007264 88 0.044
compound eye retinal cell programmed cell death GO:0046667 23 0.044
regulation of intracellular signal transduction GO:1902531 236 0.043
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.043
actomyosin structure organization GO:0031032 56 0.043
antimicrobial humoral response GO:0019730 99 0.043
vesicle organization GO:0016050 44 0.042
regulation of response to stress GO:0080134 200 0.042
anatomical structure homeostasis GO:0060249 97 0.041
regulation of cell cycle GO:0051726 291 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
rhodopsin mediated signaling pathway GO:0016056 21 0.041
heart morphogenesis GO:0003007 32 0.041
nuclear division GO:0000280 332 0.040
response to external biotic stimulus GO:0043207 293 0.040
sensory perception of taste GO:0050909 25 0.040
organophosphate catabolic process GO:0046434 112 0.040
maintenance of location GO:0051235 73 0.040
positive regulation of gene expression GO:0010628 290 0.040
cortical cytoskeleton organization GO:0030865 29 0.040
adherens junction organization GO:0034332 27 0.040
single organism catabolic process GO:0044712 228 0.040
response to abiotic stimulus GO:0009628 341 0.039
eye morphogenesis GO:0048592 260 0.039
neural precursor cell proliferation GO:0061351 75 0.039
regulation of neurogenesis GO:0050767 158 0.039
Zebrafish
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.038
intracellular protein transport GO:0006886 104 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
mitotic nuclear division GO:0007067 213 0.037
vesicle fusion GO:0006906 19 0.037
regulation of cellular protein metabolic process GO:0032268 243 0.036
immune response activating signal transduction GO:0002757 2 0.036
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.036
regulation of growth GO:0040008 233 0.036
Zebrafish Worm
mitotic cytokinesis GO:0000281 50 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
negative regulation of rna biosynthetic process GO:1902679 240 0.036
digestive system development GO:0055123 149 0.035
Zebrafish Worm
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.035
axon development GO:0061564 297 0.035
Zebrafish
spermatid development GO:0007286 98 0.035
regulation of transport GO:0051049 181 0.035
neuron projection guidance GO:0097485 241 0.034
regulation of programmed cell death GO:0043067 152 0.034
positive regulation of neurotransmitter transport GO:0051590 2 0.034
regulation of cellular response to stress GO:0080135 89 0.034
retinal cell programmed cell death GO:0046666 25 0.033
apical constriction involved in gastrulation GO:0003384 7 0.033
response to extracellular stimulus GO:0009991 116 0.033
cell adhesion GO:0007155 136 0.033
carbohydrate derivative metabolic process GO:1901135 217 0.033
arp2 3 complex mediated actin nucleation GO:0034314 3 0.033
aromatic compound catabolic process GO:0019439 166 0.033
regulation of synapse assembly GO:0051963 94 0.032
positive regulation of rna biosynthetic process GO:1902680 266 0.032
actin nucleation GO:0045010 8 0.032
molting cycle GO:0042303 56 0.032
regulation of microtubule cytoskeleton organization GO:0070507 41 0.032
dorsal ventral pattern formation GO:0009953 133 0.031
positive regulation of neurogenesis GO:0050769 41 0.031
membrane tubulation GO:0097320 4 0.031
programmed cell death GO:0012501 257 0.031
nucleotide metabolic process GO:0009117 161 0.030
vesicle mediated transport GO:0016192 381 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.030
regulation of phosphatase activity GO:0010921 3 0.030
membrane budding GO:0006900 4 0.030
spindle localization GO:0051653 22 0.030
Worm
neuromuscular synaptic transmission GO:0007274 67 0.029
chorion containing eggshell pattern formation GO:0030381 11 0.029
cellular response to dna damage stimulus GO:0006974 223 0.029
negative regulation of actin filament polymerization GO:0030837 7 0.029
cytoplasmic microtubule organization GO:0031122 22 0.029
regulation of phosphorylation GO:0042325 147 0.028
negative regulation of protein complex disassembly GO:0043242 23 0.028
negative regulation of cell cycle GO:0045786 116 0.028
neuron recognition GO:0008038 101 0.027
regulation of cell shape GO:0008360 113 0.027
sensory perception of chemical stimulus GO:0007606 116 0.027
sex differentiation GO:0007548 81 0.027
Worm
regulation of small gtpase mediated signal transduction GO:0051056 93 0.027
negative regulation of apoptotic process GO:0043066 63 0.027
regulation of hydrolase activity GO:0051336 97 0.027
regulation of organelle organization GO:0033043 196 0.027
exocytosis GO:0006887 28 0.026
positive regulation of developmental growth GO:0048639 62 0.026
Worm
cellular response to endogenous stimulus GO:0071495 80 0.026
dendrite morphogenesis GO:0048813 199 0.026
regulation of neuron projection development GO:0010975 69 0.026
Zebrafish
compound eye morphogenesis GO:0001745 249 0.026
regulation of cellular component size GO:0032535 98 0.026
Zebrafish
nuclear migration GO:0007097 20 0.026
cilium organization GO:0044782 41 0.026
purine nucleoside catabolic process GO:0006152 112 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
apoptotic process GO:0006915 159 0.025
notch receptor processing GO:0007220 13 0.025
regulation of oocyte development GO:0060281 27 0.025
mitotic dna integrity checkpoint GO:0044774 75 0.025
protein modification process GO:0036211 438 0.025
membrane protein ectodomain proteolysis GO:0006509 5 0.025
body morphogenesis GO:0010171 2 0.025
connective tissue development GO:0061448 3 0.025
proteolysis GO:0006508 192 0.024
positive regulation of organelle organization GO:0010638 65 0.024
negative regulation of gene expression GO:0010629 387 0.024
cell death GO:0008219 279 0.024
axon ensheathment in central nervous system GO:0032291 3 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.023
gtp catabolic process GO:0006184 72 0.023
positive regulation of endocytosis GO:0045807 22 0.023
cognition GO:0050890 141 0.023
response to organic substance GO:0010033 284 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
pseudocleavage GO:0030588 9 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.023
deactivation of rhodopsin mediated signaling GO:0016059 17 0.023
translation GO:0006412 69 0.022
cell recognition GO:0008037 102 0.022
regulation of immune system process GO:0002682 176 0.022
negative regulation of immune system process GO:0002683 50 0.022
regulation of erk1 and erk2 cascade GO:0070372 39 0.022
nuclear import GO:0051170 51 0.022
locomotory behavior GO:0007626 176 0.022
embryonic morphogenesis GO:0048598 206 0.022
Zebrafish Worm
synaptic transmission gabaergic GO:0051932 1 0.022
peptidyl tyrosine modification GO:0018212 24 0.022
dorsal closure GO:0007391 79 0.022
establishment of planar polarity GO:0001736 87 0.021
positive regulation of protein polymerization GO:0032273 14 0.021
ras protein signal transduction GO:0007265 88 0.021
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.021
dna damage checkpoint GO:0000077 78 0.021
positive regulation of intracellular transport GO:0032388 42 0.021
regulation of apoptotic process GO:0042981 130 0.020
establishment of nucleus localization GO:0040023 26 0.020
cellular protein modification process GO:0006464 438 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
negative regulation of phosphatase activity GO:0010923 3 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
cilium morphogenesis GO:0060271 39 0.020
aging GO:0007568 143 0.020
pole plasm protein localization GO:0007318 10 0.020
synaptic growth at neuromuscular junction GO:0051124 119 0.020
axon guidance GO:0007411 233 0.020
positive regulation of immune response GO:0050778 63 0.020
cellular protein complex disassembly GO:0043624 35 0.020
epithelial cell morphogenesis GO:0003382 25 0.019
posttranscriptional gene silencing GO:0016441 46 0.019
negative regulation of cell development GO:0010721 62 0.019
death GO:0016265 284 0.019
regulation of peptidase activity GO:0052547 39 0.019
positive regulation of feeding behavior GO:2000253 8 0.019
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.019
phospholipid metabolic process GO:0006644 23 0.019
organelle fusion GO:0048284 46 0.019
phosphorylation GO:0016310 294 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
regulation of rab gtpase activity GO:0032313 7 0.018
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.018
regulation of intracellular transport GO:0032386 64 0.018
morphogenesis of a polarized epithelium GO:0001738 93 0.018
spindle assembly GO:0051225 80 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
asymmetric protein localization GO:0008105 33 0.018
Zebrafish
rho protein signal transduction GO:0007266 14 0.018
positive regulation of transport GO:0051050 92 0.018
regulation of jnk cascade GO:0046328 40 0.018
stress activated protein kinase signaling cascade GO:0031098 55 0.018
endomembrane system organization GO:0010256 119 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
positive regulation of rab gtpase activity GO:0032851 7 0.018
parallel actin filament bundle assembly GO:0030046 2 0.017
regulation of cell cycle process GO:0010564 181 0.017
negative regulation of epithelial cell proliferation GO:0050680 4 0.017
organelle localization GO:0051640 148 0.017
Worm
protein localization GO:0008104 284 0.017
Zebrafish
organelle fission GO:0048285 340 0.017
transmission of nerve impulse GO:0019226 12 0.017
phagocytosis GO:0006909 215 0.017
nucleotide catabolic process GO:0009166 109 0.017
protein import into nucleus GO:0006606 51 0.016
response to organic cyclic compound GO:0014070 89 0.016
regulation of catabolic process GO:0009894 170 0.016
single fertilization GO:0007338 24 0.016
cellular polysaccharide metabolic process GO:0044264 11 0.016
regulation of rab protein signal transduction GO:0032483 7 0.016
nephron epithelium morphogenesis GO:0072088 3 0.016
regulation of microtubule based process GO:0032886 49 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.016
Zebrafish
glial cell development GO:0021782 27 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
phenol containing compound metabolic process GO:0018958 57 0.016
cell junction organization GO:0034330 57 0.015
Mouse
formation of primary germ layer GO:0001704 24 0.015
negative regulation of actin filament depolymerization GO:0030835 2 0.015

par-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.575
musculoskeletal system disease DOID:17 0 0.136
cardiovascular system disease DOID:1287 0 0.095
cancer DOID:162 0 0.055
disease of cellular proliferation DOID:14566 0 0.055
organ system cancer DOID:0050686 0 0.055