Drosophila melanogaster

157 known processes

comt (Dmel_CG1618)

comatose

(Aliases: dNSF-1,dnsf1,NSF-1,dNSF1,NSF1,NSF,CG1618,dNsf1,Dmel\CG1618,Nsf,CG 1618,com,dNSF,DmNSF)

comt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic vesicle recycling GO:0036465 28 0.956
establishment of synaptic vesicle localization GO:0097480 50 0.954
establishment of vesicle localization GO:0051650 51 0.920
establishment of organelle localization GO:0051656 122 0.920
vesicle mediated transport GO:0016192 381 0.917
synaptic vesicle transport GO:0048489 50 0.916
synaptic vesicle localization GO:0097479 53 0.883
vesicle localization GO:0051648 55 0.806
signal release GO:0023061 49 0.780
neuromuscular junction development GO:0007528 149 0.774
Fly
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.770
synaptic vesicle endocytosis GO:0048488 28 0.767
male courtship behavior veined wing vibration GO:0016545 21 0.719
regulation of neurotransmitter secretion GO:0046928 14 0.659
neurotransmitter secretion GO:0007269 35 0.649
male mating behavior GO:0060179 70 0.646
organelle localization GO:0051640 148 0.621
detection of light stimulus GO:0009583 58 0.608
male courtship behavior veined wing generated song production GO:0045433 20 0.593
response to abiotic stimulus GO:0009628 341 0.576
taxis GO:0042330 304 0.560
male courtship behavior veined wing extension GO:0048065 22 0.496
single organism cellular localization GO:1902580 180 0.496
Yeast
divalent inorganic cation transport GO:0072511 30 0.472
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.464
establishment of localization in cell GO:0051649 402 0.461
intracellular protein transport GO:0006886 104 0.429
Yeast
synaptic vesicle exocytosis GO:0016079 16 0.421
response to light stimulus GO:0009416 124 0.399
dendrite development GO:0016358 204 0.382
cell proliferation GO:0008283 299 0.380
positive regulation of neurotransmitter secretion GO:0001956 2 0.378
regulation of cellular localization GO:0060341 136 0.377
Rat
positive regulation of biosynthetic process GO:0009891 316 0.374
synaptic transmission GO:0007268 288 0.368
regulation of neurotransmitter levels GO:0001505 38 0.367
organophosphate metabolic process GO:0019637 195 0.355
vesicle organization GO:0016050 44 0.355
synaptic vesicle priming GO:0016082 1 0.352
regulation of secretion by cell GO:1903530 39 0.350
Rat
sodium ion transport GO:0006814 22 0.334
cellular component assembly involved in morphogenesis GO:0010927 151 0.326
Worm
positive regulation of transport GO:0051050 92 0.322
single organism membrane organization GO:0044802 93 0.317
cell division GO:0051301 248 0.312
metal ion transport GO:0030001 74 0.296
Mouse
neuroblast proliferation GO:0007405 74 0.292
muscle structure development GO:0061061 224 0.291
Worm
heart process GO:0003015 37 0.286
aging GO:0007568 143 0.279
camera type eye development GO:0043010 4 0.271
exocytosis GO:0006887 28 0.267
monovalent inorganic cation transport GO:0015672 40 0.267
Mouse
cellular protein complex assembly GO:0043623 71 0.260
Worm
single organism intracellular transport GO:1902582 207 0.254
Yeast
negative regulation of signaling GO:0023057 219 0.250
chemical homeostasis GO:0048878 92 0.248
endocytosis GO:0006897 310 0.246
pathway restricted smad protein phosphorylation GO:0060389 1 0.242
regulation of protein localization GO:0032880 76 0.221
response to radiation GO:0009314 155 0.220
positive regulation of cellular component organization GO:0051130 156 0.217
regulation of cell projection organization GO:0031344 92 0.217
learning GO:0007612 75 0.214
morphogenesis of an epithelium GO:0002009 276 0.209
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.209
apoptotic process GO:0006915 159 0.205
Worm
regulation of neuron projection development GO:0010975 69 0.197
specification of symmetry GO:0009799 13 0.193
cellular protein localization GO:0034613 160 0.180
Yeast
multicellular organismal aging GO:0010259 140 0.177
regulation of developmental growth GO:0048638 174 0.176
Fly
synaptic transmission cholinergic GO:0007271 9 0.162
regulation of localization GO:0032879 275 0.160
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.160
negative regulation of cellular metabolic process GO:0031324 382 0.160
growth GO:0040007 359 0.159
Fly
secretion by cell GO:0032940 101 0.156
single organism behavior GO:0044708 391 0.156
organic substance transport GO:0071702 257 0.154
Yeast Rat
choline metabolic process GO:0019695 1 0.147
positive regulation of cell communication GO:0010647 250 0.147
cell death GO:0008219 279 0.139
Worm
purine nucleoside biosynthetic process GO:0042451 3 0.139
mating GO:0007618 120 0.135
response to temperature stimulus GO:0009266 106 0.135
regulation of ion transport GO:0043269 39 0.134
g protein coupled receptor signaling pathway GO:0007186 136 0.134
programmed cell death GO:0012501 257 0.134
Worm
heart morphogenesis GO:0003007 32 0.129
regulation of system process GO:0044057 36 0.127
negative regulation of hormone biosynthetic process GO:0032353 1 0.127
phosphorylation GO:0016310 294 0.127
heart development GO:0007507 82 0.125
negative regulation of cellular component organization GO:0051129 108 0.124
determination of left right symmetry GO:0007368 9 0.121
inorganic ion transmembrane transport GO:0098660 73 0.119
positive regulation of nucleic acid templated transcription GO:1903508 266 0.118
locomotory behavior GO:0007626 176 0.118
cellular macromolecular complex assembly GO:0034622 153 0.118
Worm
protein localization GO:0008104 284 0.118
Yeast Rat
regulation of transport GO:0051049 181 0.118
nitrogen compound transport GO:0071705 85 0.116
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.112
regulation of phosphate metabolic process GO:0019220 210 0.112
cellular macromolecule localization GO:0070727 220 0.111
Yeast
axonogenesis GO:0007409 290 0.110
Zebrafish
regulation of neuron differentiation GO:0045664 103 0.110
adult behavior GO:0030534 137 0.109
cell growth GO:0016049 108 0.108
regulation of olfactory learning GO:0090328 8 0.107
mating behavior GO:0007617 106 0.106
positive regulation of multicellular organismal process GO:0051240 143 0.105
ribose phosphate biosynthetic process GO:0046390 28 0.105
regulation of neurogenesis GO:0050767 158 0.104
dopamine receptor signaling pathway GO:0007212 4 0.104
regulation of establishment of protein localization GO:0070201 61 0.103
purine nucleoside monophosphate metabolic process GO:0009126 50 0.101
compound eye development GO:0048749 307 0.100
regulation of epithelial cell proliferation GO:0050678 4 0.099
central nervous system development GO:0007417 201 0.099
Zebrafish
regulation of vesicle mediated transport GO:0060627 59 0.098
axon cargo transport GO:0008088 29 0.098
neuromuscular synaptic transmission GO:0007274 67 0.098
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.096
developmental growth GO:0048589 280 0.095
Fly
eye morphogenesis GO:0048592 260 0.094
Zebrafish
regulation of growth GO:0040008 233 0.094
Fly
regulation of cell development GO:0060284 215 0.093
transmembrane transport GO:0055085 139 0.090
positive regulation of response to external stimulus GO:0032103 44 0.090
neuron apoptotic process GO:0051402 17 0.089
potassium ion transport GO:0006813 20 0.088
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.087
ribonucleoside biosynthetic process GO:0042455 3 0.085
regulation of membrane potential GO:0042391 35 0.083
Zebrafish
regulation of cell morphogenesis GO:0022604 163 0.083
regulation of cell adhesion GO:0030155 27 0.082
protein complex disassembly GO:0043241 36 0.081
sensory organ morphogenesis GO:0090596 260 0.080
Zebrafish
vesicle fusion GO:0006906 19 0.080
negative regulation of cellular biosynthetic process GO:0031327 277 0.079
protein localization to organelle GO:0033365 82 0.078
sarcomere organization GO:0045214 26 0.078
regulation of chromatin modification GO:1903308 28 0.077
regulation of synaptic vesicle exocytosis GO:2000300 3 0.077
purine nucleoside metabolic process GO:0042278 127 0.077
organic acid metabolic process GO:0006082 103 0.076
macromolecular complex assembly GO:0065003 256 0.075
regulation of cell cycle GO:0051726 291 0.075
anatomical structure homeostasis GO:0060249 97 0.075
regulation of response to external stimulus GO:0032101 115 0.075
stem cell proliferation GO:0072089 88 0.074
nucleoside triphosphate metabolic process GO:0009141 120 0.073
regulation of nervous system development GO:0051960 248 0.072
Fly
regulation of necrotic cell death GO:0010939 1 0.072
cytokinesis GO:0000910 90 0.071
organelle assembly GO:0070925 198 0.070
Yeast Worm
membrane organization GO:0061024 112 0.070
establishment of protein localization GO:0045184 163 0.070
Yeast Rat
regulation of metal ion transport GO:0010959 15 0.070
neuronal action potential GO:0019228 10 0.069
Zebrafish
positive regulation of developmental process GO:0051094 143 0.069
positive regulation of signaling GO:0023056 243 0.068
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.067
Fly
single organism biosynthetic process GO:0044711 206 0.067
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.066
inorganic cation transmembrane transport GO:0098662 61 0.066
neurotransmitter metabolic process GO:0042133 2 0.064
peptidyl threonine phosphorylation GO:0018107 2 0.063
forebrain development GO:0030900 2 0.061
Zebrafish
negative regulation of gene expression GO:0010629 387 0.060
determination of bilateral symmetry GO:0009855 13 0.060
positive regulation of cell motility GO:2000147 3 0.060
negative regulation of biosynthetic process GO:0009890 277 0.059
positive regulation of phosphorus metabolic process GO:0010562 139 0.059
muscle cell development GO:0055001 50 0.059
Worm
nuclear division GO:0000280 332 0.059
positive regulation of rna metabolic process GO:0051254 271 0.058
cellular protein complex disassembly GO:0043624 35 0.058
neuron projection extension GO:1990138 32 0.058
organonitrogen compound metabolic process GO:1901564 318 0.058
positive regulation of transcription dna templated GO:0045893 266 0.058
regulation of cell differentiation GO:0045595 302 0.058
response to heat GO:0009408 63 0.057
regulation of sodium ion transport GO:0002028 5 0.057
secretion GO:0046903 109 0.057
neurotransmitter transport GO:0006836 37 0.057
heart contraction GO:0060047 26 0.057
mitochondrial fusion GO:0008053 7 0.057
cell fate determination GO:0001709 91 0.057
carboxylic acid metabolic process GO:0019752 92 0.056
dendrite morphogenesis GO:0048813 199 0.056
homeostatic process GO:0042592 199 0.056
positive regulation of protein localization to nucleus GO:1900182 21 0.056
positive regulation of phosphate metabolic process GO:0045937 139 0.056
ion transmembrane transport GO:0034220 122 0.055
cellular amino acid metabolic process GO:0006520 61 0.055
catabolic process GO:0009056 409 0.054
regulation of protein transport GO:0051223 57 0.054
negative regulation of programmed cell death GO:0043069 72 0.054
regulation of cellular ketone metabolic process GO:0010565 3 0.054
regulation of synapse structure and activity GO:0050803 128 0.054
Fly
mitotic cytokinesis GO:0000281 50 0.054
striated muscle myosin thick filament assembly GO:0071688 3 0.054
Worm
ribonucleoside triphosphate metabolic process GO:0009199 119 0.054
regulation of synaptic transmission GO:0050804 69 0.054
macromolecular complex disassembly GO:0032984 37 0.053
regulation of organelle organization GO:0033043 196 0.053
positive regulation of intracellular protein transport GO:0090316 30 0.053
response to cold GO:0009409 13 0.053
retina development in camera type eye GO:0060041 4 0.053
regulation of dna metabolic process GO:0051052 34 0.052
nucleoside phosphate metabolic process GO:0006753 162 0.052
protein transport GO:0015031 155 0.051
Yeast Rat
cellular amine metabolic process GO:0044106 12 0.051
striated muscle cell development GO:0055002 50 0.051
Worm
cell cell junction assembly GO:0007043 38 0.051
cellular ketone metabolic process GO:0042180 24 0.051
axon development GO:0061564 297 0.051
Zebrafish
negative regulation of rna metabolic process GO:0051253 251 0.050
ribonucleoside monophosphate metabolic process GO:0009161 51 0.050
embryonic morphogenesis GO:0048598 206 0.049
membrane budding GO:0006900 4 0.049
regulation of cell death GO:0010941 173 0.049
cytoskeleton dependent cytokinesis GO:0061640 81 0.048
regulation of sequestering of calcium ion GO:0051282 3 0.048
single organism cell adhesion GO:0098602 47 0.047
protein phosphorylation GO:0006468 169 0.046
regulation of axonogenesis GO:0050770 32 0.045
protein complex assembly GO:0006461 200 0.045
adult locomotory behavior GO:0008344 76 0.044
regulation of secretion GO:0051046 44 0.044
Rat
axon target recognition GO:0007412 16 0.044
cellular response to carbon dioxide GO:0071244 2 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.042
positive regulation of cell migration GO:0030335 2 0.042
neuron death GO:0070997 27 0.041
tube morphogenesis GO:0035239 191 0.041
Fly
negative regulation of cell cycle process GO:0010948 109 0.041
negative regulation of epithelial cell proliferation GO:0050680 4 0.041
phototransduction visible light GO:0007603 27 0.041
axon extension GO:0048675 32 0.041
actin cytoskeleton organization GO:0030036 206 0.041
Worm
positive regulation of protein import into nucleus GO:0042307 21 0.040
actomyosin structure organization GO:0031032 56 0.040
Worm
visual learning GO:0008542 4 0.040
somatic stem cell division GO:0048103 37 0.040
regulation of lipid metabolic process GO:0019216 15 0.040
regulation of blood circulation GO:1903522 21 0.040
determination of adult lifespan GO:0008340 137 0.039
regulation of intracellular transport GO:0032386 64 0.039
necrotic cell death GO:0070265 1 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.039
membrane tubulation GO:0097320 4 0.038
mapk cascade GO:0000165 107 0.038
death GO:0016265 284 0.038
Worm
regulation of steroid metabolic process GO:0019218 2 0.038
negative regulation of developmental growth GO:0048640 64 0.038
regulation of peptidyl lysine acetylation GO:2000756 7 0.038
metal ion homeostasis GO:0055065 44 0.037
calcium ion transmembrane transport GO:0070588 17 0.037
regulation of cytoskeleton organization GO:0051493 89 0.037
locomotor rhythm GO:0045475 56 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
regulation of programmed cell death GO:0043067 152 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.035
Worm
positive regulation of protein transport GO:0051222 37 0.035
head development GO:0060322 135 0.035
Zebrafish
regulation of ion homeostasis GO:2000021 5 0.035
hindbrain development GO:0030902 2 0.035
protein kinase a signaling GO:0010737 2 0.035
calcium ion transport GO:0006816 24 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
regulation of lipid biosynthetic process GO:0046890 6 0.034
organonitrogen compound biosynthetic process GO:1901566 117 0.034
single organism membrane fusion GO:0044801 42 0.034
stem cell development GO:0048864 79 0.034
positive regulation of apoptotic signaling pathway GO:2001235 4 0.034
apoptotic signaling pathway GO:0097190 27 0.033
positive regulation of secretion by cell GO:1903532 20 0.033
cellular biogenic amine catabolic process GO:0042402 1 0.033
gliogenesis GO:0042063 80 0.033
Zebrafish
circulatory system development GO:0072359 82 0.033
myofibril assembly GO:0030239 36 0.033
Worm
regulation of chromatin organization GO:1902275 32 0.033
atp biosynthetic process GO:0006754 2 0.032
spinal cord development GO:0021510 1 0.032
muscle system process GO:0003012 21 0.032
detection of external stimulus GO:0009581 66 0.032
tissue morphogenesis GO:0048729 297 0.032
Fly
blood circulation GO:0008015 26 0.032
epithelial cell differentiation GO:0030855 322 0.032
cation transport GO:0006812 110 0.031
Mouse
single organismal cell cell adhesion GO:0016337 45 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.031
atp metabolic process GO:0046034 49 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
regulation of protein targeting GO:1903533 29 0.030
nuclear transport GO:0051169 72 0.030
synaptic growth at neuromuscular junction GO:0051124 119 0.030
Fly
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.030
epithelial tube morphogenesis GO:0060562 88 0.030
Fly
regulation of heart contraction GO:0008016 21 0.030
striated muscle cell differentiation GO:0051146 90 0.030
Worm
camera type eye morphogenesis GO:0048593 2 0.029
skeletal muscle fiber development GO:0048741 3 0.029
action potential GO:0001508 13 0.029
Zebrafish
gland development GO:0048732 191 0.029
regionalization GO:0003002 416 0.029
organonitrogen compound catabolic process GO:1901565 128 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
neuromuscular process GO:0050905 21 0.029
nucleoside monophosphate metabolic process GO:0009123 52 0.029
positive regulation of cell differentiation GO:0045597 64 0.029
acetate ester metabolic process GO:1900619 2 0.029
regulation of mrna processing GO:0050684 71 0.028
alcohol metabolic process GO:0006066 25 0.028
response to mechanical stimulus GO:0009612 28 0.028
regulation of anatomical structure morphogenesis GO:0022603 242 0.028
extrinsic apoptotic signaling pathway GO:0097191 1 0.028
regulation of cellular component size GO:0032535 98 0.028
clathrin mediated endocytosis GO:0072583 7 0.028
purine ribonucleoside metabolic process GO:0046128 127 0.027
positive regulation of secretion GO:0051047 22 0.027
compound eye morphogenesis GO:0001745 249 0.027
single organism catabolic process GO:0044712 228 0.027
transmission of nerve impulse GO:0019226 12 0.026
Zebrafish
regulation of intracellular protein transport GO:0033157 46 0.026
chromosome organization GO:0051276 360 0.026
regulation of protein deacetylation GO:0090311 2 0.026
regulation of actin filament based process GO:0032970 42 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.026
cellular homeostasis GO:0019725 80 0.026
intracellular transport GO:0046907 228 0.026
Yeast
regulation of mrna metabolic process GO:1903311 72 0.026
neural precursor cell proliferation GO:0061351 75 0.026
tube development GO:0035295 244 0.026
Fly
dopamine biosynthetic process GO:0042416 3 0.025
chromatin organization GO:0006325 207 0.025
ovarian follicle cell development GO:0030707 248 0.025
regulation of behavior GO:0050795 75 0.025
regulation of locomotion GO:0040012 42 0.025
cardiovascular system development GO:0072358 82 0.025
positive regulation of lipid metabolic process GO:0045834 4 0.025
ion homeostasis GO:0050801 55 0.025
meiotic nuclear division GO:0007126 151 0.025
neurotransmitter receptor metabolic process GO:0045213 3 0.025
ribonucleotide metabolic process GO:0009259 145 0.025
mesenchymal cell development GO:0014031 1 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
ion transport GO:0006811 145 0.024
Mouse
small molecule metabolic process GO:0044281 305 0.024
positive regulation of organelle organization GO:0010638 65 0.024
positive regulation of gene expression GO:0010628 290 0.024
regulation of synaptic vesicle transport GO:1902803 10 0.024
organelle fission GO:0048285 340 0.024
myotube cell development GO:0014904 3 0.023
synapse assembly GO:0007416 143 0.023
Fly
multicellular organismal reproductive behavior GO:0033057 110 0.023
regulation of protein complex disassembly GO:0043244 29 0.023
positive regulation of axonogenesis GO:0050772 2 0.023
regulation of endocytosis GO:0030100 37 0.023
stem cell differentiation GO:0048863 117 0.023
protein complex biogenesis GO:0070271 201 0.023
detection of stimulus GO:0051606 156 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
single organism nuclear import GO:1902593 51 0.023
negative regulation of mitotic cell cycle GO:0045930 109 0.022
ribonucleoside monophosphate catabolic process GO:0009158 39 0.022
developmental growth involved in morphogenesis GO:0060560 65 0.022
sperm motility GO:0030317 12 0.022
regulation of ion transmembrane transport GO:0034765 27 0.022
mesenchymal cell differentiation GO:0048762 1 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
Fly
neuron recognition GO:0008038 101 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
cellular response to light stimulus GO:0071482 37 0.022
positive regulation of neurotransmitter transport GO:0051590 2 0.022
protein targeting GO:0006605 64 0.021
cell cycle arrest GO:0007050 4 0.021
regulation of protein localization to nucleus GO:1900180 29 0.021
extracellular structure organization GO:0043062 46 0.021
positive regulation of cell death GO:0010942 69 0.021
eye development GO:0001654 323 0.021
Zebrafish
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.021
regulation of response to stress GO:0080134 200 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
regulation of protein import into nucleus GO:0042306 28 0.021
amine metabolic process GO:0009308 12 0.020
bmp signaling pathway GO:0030509 27 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
cell type specific apoptotic process GO:0097285 38 0.020
detection of abiotic stimulus GO:0009582 66 0.020
monocarboxylic acid transport GO:0015718 3 0.020
acid secretion GO:0046717 1 0.020
positive regulation of locomotion GO:0040017 8 0.020
muscle cell differentiation GO:0042692 103 0.020
Worm
regulation of exocytosis GO:0017157 6 0.020
Rat
purine ribonucleotide biosynthetic process GO:0009152 28 0.020
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.020
purine containing compound metabolic process GO:0072521 155 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
protein modification process GO:0036211 438 0.019
intracellular mrna localization GO:0008298 66 0.019
embryonic organ development GO:0048568 50 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
myotube differentiation GO:0014902 46 0.019
negative regulation of signal transduction GO:0009968 206 0.019
positive regulation of growth GO:0045927 75 0.019
negative regulation of nervous system development GO:0051961 92 0.019
larval heart development GO:0007508 6 0.019
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.019
histone modification GO:0016570 106 0.018
purine nucleotide biosynthetic process GO:0006164 29 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.018
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
cytosolic calcium ion transport GO:0060401 2 0.018
sensory perception of sound GO:0007605 56 0.018
regulation of histone modification GO:0031056 20 0.018
cell adhesion GO:0007155 136 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
regulation of cell growth GO:0001558 43 0.018
macromolecule catabolic process GO:0009057 161 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.018
anion transport GO:0006820 41 0.018
rna splicing GO:0008380 83 0.018
mitotic nuclear division GO:0007067 213 0.018
negative regulation of cell communication GO:0010648 223 0.018
divalent inorganic cation homeostasis GO:0072507 29 0.017
dna metabolic process GO:0006259 227 0.017
cell recognition GO:0008037 102 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
chemotaxis GO:0006935 249 0.017
positive regulation of signal transduction GO:0009967 223 0.017
chromatin modification GO:0016568 147 0.017
cell migration GO:0016477 238 0.017
histone acetylation GO:0016573 38 0.017
body morphogenesis GO:0010171 2 0.017
regulation of histone deacetylation GO:0031063 2 0.017
phosphatidylinositol mediated signaling GO:0048015 4 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
regulation of neuron apoptotic process GO:0043523 16 0.017
receptor mediated endocytosis GO:0006898 21 0.016
Worm
rna processing GO:0006396 147 0.016
cytoplasmic transport GO:0016482 130 0.016
Yeast
neuron cell cell adhesion GO:0007158 1 0.016
negative regulation of transcription dna templated GO:0045892 237 0.016
membrane depolarization GO:0051899 4 0.016
divalent metal ion transport GO:0070838 26 0.016
cellular metal ion homeostasis GO:0006875 31 0.016
regulation of neurotransmitter transport GO:0051588 14 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
axon ensheathment in central nervous system GO:0032291 3 0.016
inositol lipid mediated signaling GO:0048017 4 0.016
anion transmembrane transport GO:0098656 26 0.016
carbohydrate metabolic process GO:0005975 82 0.016
negative regulation of cell death GO:0060548 81 0.016
startle response GO:0001964 16 0.016
positive regulation of protein deacetylation GO:0090312 2 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
epithelial cell development GO:0002064 274 0.015
negative regulation of sequestering of calcium ion GO:0051283 2 0.015
negative regulation of synaptic transmission GO:0050805 12 0.015
biological adhesion GO:0022610 138 0.015
nucleoside biosynthetic process GO:0009163 3 0.015
regulation of carbohydrate metabolic process GO:0006109 10 0.015
lipid metabolic process GO:0006629 121 0.015
response to glucose GO:0009749 2 0.015
skeletal muscle organ development GO:0060538 48 0.015
sequestering of calcium ion GO:0051208 5 0.015
cytosolic calcium ion homeostasis GO:0051480 11 0.015
positive regulation of apoptotic process GO:0043065 47 0.015
nucleotide catabolic process GO:0009166 109 0.014
non sensory hair organization GO:0035316 47 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
endomembrane system organization GO:0010256 119 0.014
nucleoside triphosphate biosynthetic process GO:0009142 2 0.014

comt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.088
disease of anatomical entity DOID:7 0 0.088
nervous system disease DOID:863 0 0.088
neuropathy DOID:870 0 0.088
disease of metabolism DOID:0014667 0 0.040
central nervous system disease DOID:331 0 0.030
neurodegenerative disease DOID:1289 0 0.030
vascular disease DOID:178 0 0.028
cardiovascular system disease DOID:1287 0 0.028
charcot marie tooth disease DOID:10595 0 0.015
long qt syndrome DOID:2843 0 0.014