Drosophila melanogaster

30 known processes

Drs (Dmel_CG10810)

Drosomycin

(Aliases: Crp,DIM 19,DRO,Dros,DRS,drom,Dmel\CG10810,BcDNA:LP03851,drsm,Drm,DROM,CG10810,Drom,drm,dmy1,drs)

Drs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.915
antibacterial humoral response GO:0019731 44 0.902
defense response GO:0006952 300 0.891
defense response to other organism GO:0098542 225 0.858
defense response to gram positive bacterium GO:0050830 41 0.818
humoral immune response GO:0006959 117 0.703
defense response to bacterium GO:0042742 178 0.692
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.598
immune response GO:0006955 246 0.584
response to bacterium GO:0009617 198 0.577
response to biotic stimulus GO:0009607 294 0.564
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.530
response to external biotic stimulus GO:0043207 293 0.521
immune system process GO:0002376 347 0.493
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.482
activation of innate immune response GO:0002218 4 0.444
response to other organism GO:0051707 293 0.408
innate immune response GO:0045087 144 0.390
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.365
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.344
defense response to gram negative bacterium GO:0050829 94 0.336
pattern recognition receptor signaling pathway GO:0002221 2 0.323
defense response to fungus GO:0050832 48 0.282
innate immune response activating signal transduction GO:0002758 2 0.280
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.270
response to peptidoglycan GO:0032494 2 0.240
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.231
peptidoglycan metabolic process GO:0000270 3 0.228
defense response to virus GO:0051607 23 0.209
antifungal humoral response GO:0019732 12 0.209
regulation of antibacterial peptide production GO:0002786 22 0.204
positive regulation of antibacterial peptide production GO:0002803 20 0.197
glycosaminoglycan catabolic process GO:0006027 3 0.191
regulation of defense response GO:0031347 102 0.188
antibacterial peptide production GO:0002778 22 0.183
antimicrobial humoral response GO:0019730 99 0.180
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.180
regulation of defense response to bacterium GO:1900424 30 0.147
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.138
antibacterial peptide biosynthetic process GO:0002780 22 0.137
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.126
positive regulation of defense response GO:0031349 59 0.126
determination of adult lifespan GO:0008340 137 0.125
response to lipopolysaccharide GO:0032496 4 0.121
melanization defense response GO:0035006 45 0.119
secondary metabolic process GO:0019748 75 0.119
positive regulation of defense response to bacterium GO:1900426 23 0.117
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.117
positive regulation of antimicrobial peptide production GO:0002225 28 0.113
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.108
production of molecular mediator of immune response GO:0002440 46 0.106
negative regulation of signaling GO:0023057 219 0.102
antimicrobial peptide biosynthetic process GO:0002777 38 0.099
cellular response to lipopolysaccharide GO:0071222 3 0.096
positive regulation of antimicrobial humoral response GO:0002760 28 0.095
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.095
negative regulation of defense response to bacterium GO:1900425 7 0.095
peptide biosynthetic process GO:0043043 42 0.091
positive regulation of cellular amide metabolic process GO:0034250 26 0.085
negative regulation of cell communication GO:0010648 223 0.084
organonitrogen compound metabolic process GO:1901564 318 0.083
antimicrobial peptide production GO:0002775 46 0.082
peptidoglycan catabolic process GO:0009253 3 0.080
response to organic substance GO:0010033 284 0.079
positive regulation of response to stimulus GO:0048584 323 0.075
regulation of innate immune response GO:0045088 71 0.074
appendage morphogenesis GO:0035107 397 0.073
peptide metabolic process GO:0006518 80 0.071
cellular response to molecule of bacterial origin GO:0071219 3 0.070
immune response activating signal transduction GO:0002757 2 0.069
immune response regulating signaling pathway GO:0002764 2 0.068
positive regulation of biosynthetic process GO:0009891 316 0.067
phosphorylation GO:0016310 294 0.065
regulation of humoral immune response GO:0002920 51 0.065
negative regulation of response to stimulus GO:0048585 258 0.064
positive regulation of response to biotic stimulus GO:0002833 31 0.062
negative regulation of signal transduction GO:0009968 206 0.062
toll signaling pathway GO:0008063 25 0.061
negative regulation of cellular metabolic process GO:0031324 382 0.060
regulation of response to stress GO:0080134 200 0.059
wing disc morphogenesis GO:0007472 344 0.056
regulation of multi organism process GO:0043900 131 0.055
positive regulation of immune response GO:0050778 63 0.053
intracellular signal transduction GO:0035556 300 0.053
cellular response to chemical stimulus GO:0070887 199 0.053
multicellular organismal aging GO:0010259 140 0.053
imaginal disc derived wing morphogenesis GO:0007476 337 0.052
organonitrogen compound biosynthetic process GO:1901566 117 0.051
positive regulation of multi organism process GO:0043902 40 0.051
carbohydrate derivative metabolic process GO:1901135 217 0.050
regulation of intracellular signal transduction GO:1902531 236 0.050
positive regulation of humoral immune response GO:0002922 28 0.049
catabolic process GO:0009056 409 0.048
aging GO:0007568 143 0.048
response to fungus GO:0009620 50 0.047
negative regulation of immune system process GO:0002683 50 0.047
pigment metabolic process GO:0042440 84 0.047
regulation of mapk cascade GO:0043408 92 0.046
vesicle mediated transport GO:0016192 381 0.045
response to oxygen containing compound GO:1901700 200 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.045
positive regulation of cellular biosynthetic process GO:0031328 316 0.045
organic substance catabolic process GO:1901575 308 0.044
imaginal disc derived appendage development GO:0048737 399 0.044
negative regulation of defense response GO:0031348 35 0.043
amide biosynthetic process GO:0043604 42 0.042
regulation of immune response GO:0050776 118 0.041
small molecule metabolic process GO:0044281 305 0.040
appendage development GO:0048736 401 0.040
regulation of antimicrobial peptide production GO:0002784 44 0.039
regulation of immune effector process GO:0002697 52 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
regulation of response to external stimulus GO:0032101 115 0.038
organonitrogen compound catabolic process GO:1901565 128 0.038
regulation of antimicrobial humoral response GO:0002759 50 0.038
immune effector process GO:0002252 98 0.037
response to nitrogen compound GO:1901698 90 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.036
stress activated mapk cascade GO:0051403 52 0.035
cellular response to organic substance GO:0071310 132 0.035
negative regulation of intracellular signal transduction GO:1902532 57 0.034
carbohydrate derivative catabolic process GO:1901136 118 0.033
cellular amide metabolic process GO:0043603 80 0.033
regionalization GO:0003002 416 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
macromolecule catabolic process GO:0009057 161 0.032
regulation of cellular response to stress GO:0080135 89 0.032
endocytosis GO:0006897 310 0.031
dorsal ventral pattern formation GO:0009953 133 0.031
regulation of phosphorus metabolic process GO:0051174 210 0.031
regulation of immune system process GO:0002682 176 0.030
response to virus GO:0009615 28 0.030
negative regulation of innate immune response GO:0045824 30 0.030
phagocytosis GO:0006909 215 0.030
cellular response to oxygen containing compound GO:1901701 79 0.029
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.029
cellular catabolic process GO:0044248 372 0.029
regulation of jnk cascade GO:0046328 40 0.029
cellular response to biotic stimulus GO:0071216 4 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.028
response to organophosphorus GO:0046683 2 0.028
organic acid metabolic process GO:0006082 103 0.028
growth GO:0040007 359 0.027
positive regulation of immune system process GO:0002684 68 0.027
response to endogenous stimulus GO:0009719 119 0.027
melanin metabolic process GO:0006582 47 0.027
positive regulation of melanization defense response GO:0035008 1 0.027
negative regulation of phosphorylation GO:0042326 35 0.027
regulation of response to biotic stimulus GO:0002831 63 0.026
regulation of melanization defense response GO:0035007 6 0.026
response to organonitrogen compound GO:0010243 75 0.026
aminoglycan catabolic process GO:0006026 6 0.026
positive regulation of signaling GO:0023056 243 0.026
negative regulation of gene expression GO:0010629 387 0.026
regulation of phosphorylation GO:0042325 147 0.025
negative regulation of phosphate metabolic process GO:0045936 45 0.025
response to abiotic stimulus GO:0009628 341 0.025
death GO:0016265 284 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
signal transduction by phosphorylation GO:0023014 107 0.024
establishment of localization in cell GO:0051649 402 0.024
regulation of cellular amide metabolic process GO:0034248 39 0.024
positive regulation of cell communication GO:0010647 250 0.024
single organism catabolic process GO:0044712 228 0.024
jnk cascade GO:0007254 50 0.024
amine catabolic process GO:0009310 1 0.024
epithelial cell differentiation GO:0030855 322 0.024
positive regulation of response to external stimulus GO:0032103 44 0.024
aminoglycan metabolic process GO:0006022 18 0.023
taxis GO:0042330 304 0.023
cell death GO:0008219 279 0.023
cellular amino acid metabolic process GO:0006520 61 0.022
regulation of secondary metabolic process GO:0043455 7 0.022
nuclear division GO:0000280 332 0.022
positive regulation of signal transduction GO:0009967 223 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
response to molecule of bacterial origin GO:0002237 7 0.022
organelle fission GO:0048285 340 0.021
positive regulation of innate immune response GO:0045089 38 0.021
chemotaxis GO:0006935 249 0.021
organic hydroxy compound metabolic process GO:1901615 83 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.020
oxoacid metabolic process GO:0043436 103 0.020
body morphogenesis GO:0010171 2 0.020
cellular amine metabolic process GO:0044106 12 0.020
organophosphate metabolic process GO:0019637 195 0.020
negative regulation of phosphorus metabolic process GO:0010563 45 0.019
cellular ketone metabolic process GO:0042180 24 0.019
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.019
synaptic transmission GO:0007268 288 0.019
ethanolamine containing compound metabolic process GO:0042439 4 0.019
amine metabolic process GO:0009308 12 0.019
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.019
protein modification process GO:0036211 438 0.019
positive regulation of immune effector process GO:0002699 28 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
benzene containing compound metabolic process GO:0042537 3 0.019
camera type eye development GO:0043010 4 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
regulation of tube architecture open tracheal system GO:0035152 68 0.018
protein processing GO:0016485 68 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
negative regulation of immune response GO:0050777 39 0.018
biological adhesion GO:0022610 138 0.018
spermatid differentiation GO:0048515 114 0.018
respiratory system development GO:0060541 213 0.018
developmental growth GO:0048589 280 0.018
wound healing GO:0042060 75 0.017
regulation of stress activated mapk cascade GO:0032872 41 0.017
dorsal ventral axis specification GO:0009950 66 0.017
single organism behavior GO:0044708 391 0.017
mapk cascade GO:0000165 107 0.017
regulation of transport GO:0051049 181 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
developmental programmed cell death GO:0010623 138 0.017
organelle assembly GO:0070925 198 0.017
tissue death GO:0016271 102 0.017
ovarian follicle cell development GO:0030707 248 0.017
programmed cell death GO:0012501 257 0.017
actin filament based process GO:0030029 220 0.017
regulation of cell cycle GO:0051726 291 0.017
intracellular transport GO:0046907 228 0.017
maintenance of location GO:0051235 73 0.017
cell adhesion GO:0007155 136 0.016
regulation of production of molecular mediator of immune response GO:0002700 44 0.016
cell recognition GO:0008037 102 0.016
negative regulation of mapk cascade GO:0043409 23 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
regulation of localization GO:0032879 275 0.016
response to wounding GO:0009611 94 0.016
forebrain development GO:0030900 2 0.016
glycosaminoglycan metabolic process GO:0030203 11 0.016
gland morphogenesis GO:0022612 145 0.016
positive regulation of cell migration GO:0030335 2 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
axon guidance GO:0007411 233 0.016
positive regulation of gene expression GO:0010628 290 0.016
gene silencing GO:0016458 138 0.016
anatomical structure homeostasis GO:0060249 97 0.016
regulation of molecular function GO:0065009 217 0.016
regulation of catalytic activity GO:0050790 185 0.016
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.016
cellular protein modification process GO:0006464 438 0.016
detection of stimulus GO:0051606 156 0.015
neuron projection guidance GO:0097485 241 0.015
negative regulation of response to biotic stimulus GO:0002832 12 0.015
retina development in camera type eye GO:0060041 4 0.015
phenol containing compound metabolic process GO:0018958 57 0.015
single organism cellular localization GO:1902580 180 0.015
developmental maturation GO:0021700 172 0.015
telencephalon development GO:0021537 2 0.015
epithelial cell development GO:0002064 274 0.015
protein transport GO:0015031 155 0.015
gene silencing by rna GO:0031047 57 0.015
autophagic cell death GO:0048102 83 0.015
homeostatic process GO:0042592 199 0.015
chromosome segregation GO:0007059 157 0.015
meiotic nuclear division GO:0007126 151 0.015
single organism intracellular transport GO:1902582 207 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
epidermal cell differentiation GO:0009913 51 0.015
stress activated protein kinase signaling cascade GO:0031098 55 0.014
single organism biosynthetic process GO:0044711 206 0.014
ion transport GO:0006811 145 0.014
exocrine system development GO:0035272 162 0.014
connective tissue development GO:0061448 3 0.014
xenobiotic catabolic process GO:0042178 1 0.014
regulation of growth GO:0040008 233 0.014
response to lipid GO:0033993 38 0.014
open tracheal system development GO:0007424 204 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
neurological system process GO:0050877 358 0.014
cell junction organization GO:0034330 57 0.014
acetylcholine catabolic process GO:0006581 1 0.014
organic substance transport GO:0071702 257 0.014
regulation of hydrolase activity GO:0051336 97 0.014
regulation of protein metabolic process GO:0051246 256 0.014
protein localization GO:0008104 284 0.014
positive regulation of cell motility GO:2000147 3 0.014
melanotic encapsulation of foreign target GO:0035011 30 0.014
salivary gland histolysis GO:0035070 88 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
cell cell junction organization GO:0045216 55 0.014
response to organic cyclic compound GO:0014070 89 0.013
organelle localization GO:0051640 148 0.013
limb development GO:0060173 1 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
response to radiation GO:0009314 155 0.013
male gamete generation GO:0048232 201 0.013
nephron development GO:0072006 3 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
nucleotide metabolic process GO:0009117 161 0.013
imaginal disc derived wing hair organization GO:0035317 45 0.013
protein maturation GO:0051604 71 0.013
cell proliferation GO:0008283 299 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of proteolysis GO:0030162 87 0.013
mitotic nuclear division GO:0007067 213 0.013
spindle organization GO:0007051 253 0.013
response to light stimulus GO:0009416 124 0.013
segmentation GO:0035282 207 0.013
gland development GO:0048732 191 0.013
axonogenesis GO:0007409 290 0.013
regulation of cell differentiation GO:0045595 302 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
protein phosphorylation GO:0006468 169 0.013
salivary gland development GO:0007431 162 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
purine containing compound metabolic process GO:0072521 155 0.013
non sensory hair organization GO:0035316 47 0.013
negative regulation of response to external stimulus GO:0032102 22 0.013
macromolecular complex assembly GO:0065003 256 0.013
protein complex assembly GO:0006461 200 0.013
nephron tubule development GO:0072080 3 0.012
skin development GO:0043588 65 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
aromatic compound catabolic process GO:0019439 166 0.012
salivary gland morphogenesis GO:0007435 145 0.012
spermatogenesis GO:0007283 200 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
chaeta development GO:0022416 97 0.012
septate junction assembly GO:0019991 26 0.012
localization of cell GO:0051674 257 0.012
cellular homeostasis GO:0019725 80 0.012
nucleoside metabolic process GO:0009116 127 0.012
cell cycle checkpoint GO:0000075 95 0.012
positive regulation of molecular function GO:0044093 136 0.012
meiotic cell cycle GO:0051321 171 0.012
synaptic target recognition GO:0008039 45 0.012
pigmentation GO:0043473 75 0.012
heterocycle catabolic process GO:0046700 166 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
establishment of protein localization GO:0045184 163 0.012
imaginal disc pattern formation GO:0007447 91 0.012
proteolysis GO:0006508 192 0.012
kidney morphogenesis GO:0060993 3 0.012
cation homeostasis GO:0055080 51 0.012
hemolymph coagulation GO:0042381 10 0.012
histolysis GO:0007559 102 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of cell death GO:0010941 173 0.011
regulation of gene silencing GO:0060968 63 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
skeletal muscle fiber development GO:0048741 3 0.011
cell motility GO:0048870 251 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
regulation of cell cycle process GO:0010564 181 0.011
blastoderm segmentation GO:0007350 159 0.011
cell migration GO:0016477 238 0.011
cellular macromolecule localization GO:0070727 220 0.011
molting cycle process GO:0022404 29 0.011
negative regulation of developmental process GO:0051093 201 0.011
ovarian follicle cell migration GO:0007297 121 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
endomembrane system organization GO:0010256 119 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
lateral inhibition GO:0046331 206 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
compound eye development GO:0048749 307 0.011
neuromuscular junction development GO:0007528 149 0.011
adult behavior GO:0030534 137 0.011
acetylcholine metabolic process GO:0008291 2 0.011
mitotic spindle organization GO:0007052 220 0.011
rna processing GO:0006396 147 0.011
cellular biogenic amine catabolic process GO:0042402 1 0.011
regulation of anatomical structure size GO:0090066 163 0.011
regulation of catabolic process GO:0009894 170 0.011
nephron epithelium development GO:0072009 3 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
hair cell differentiation GO:0035315 47 0.011
protein complex biogenesis GO:0070271 201 0.011
choline metabolic process GO:0019695 1 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
regulation of developmental growth GO:0048638 174 0.010
single organism cell adhesion GO:0098602 47 0.010
stem cell proliferation GO:0072089 88 0.010
positive regulation of cell death GO:0010942 69 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
regulation of synapse organization GO:0050807 110 0.010
kidney development GO:0001822 3 0.010
mitotic dna integrity checkpoint GO:0044774 75 0.010
cellular protein localization GO:0034613 160 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
acetate ester metabolic process GO:1900619 2 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
axis specification GO:0009798 167 0.010
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of nervous system development GO:0051960 248 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
intracellular protein transport GO:0006886 104 0.010
response to hexose GO:0009746 3 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010

Drs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
nervous system disease DOID:863 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.011