Drosophila melanogaster

54 known processes

sdk (Dmel_CG5227)

sidekick

(Aliases: CT16627,Dmel\CG5227,BcDNA:LD22322,CG5227,BcDNA:RE63453,EG:BACR19J1.1)

sdk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.770
eye morphogenesis GO:0048592 260 0.725
negative regulation of erbb signaling pathway GO:1901185 29 0.689
regulation of erbb signaling pathway GO:1901184 42 0.605
epidermal growth factor receptor signaling pathway GO:0007173 58 0.555
ommatidial rotation GO:0016318 20 0.546
erbb signaling pathway GO:0038127 58 0.431
protein modification process GO:0036211 438 0.312
cellular protein modification process GO:0006464 438 0.295
compound eye photoreceptor development GO:0042051 78 0.286
morphogenesis of a polarized epithelium GO:0001738 93 0.281
brain development GO:0007420 120 0.270
establishment or maintenance of cell polarity GO:0007163 167 0.270
compound eye morphogenesis GO:0001745 249 0.261
compound eye development GO:0048749 307 0.251
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.222
macromolecular complex assembly GO:0065003 256 0.211
single organism cell adhesion GO:0098602 47 0.205
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.186
eye photoreceptor cell differentiation GO:0001754 145 0.173
establishment of tissue polarity GO:0007164 87 0.163
imaginal disc derived appendage development GO:0048737 399 0.162
sensory organ morphogenesis GO:0090596 260 0.143
establishment of ommatidial planar polarity GO:0042067 49 0.136
compound eye cone cell differentiation GO:0042675 13 0.135
cell proliferation GO:0008283 299 0.133
enzyme linked receptor protein signaling pathway GO:0007167 179 0.116
muscle attachment GO:0016203 36 0.116
single organismal cell cell adhesion GO:0016337 45 0.114
establishment of planar polarity GO:0001736 87 0.109
eye photoreceptor cell development GO:0042462 81 0.108
negative regulation of signaling GO:0023057 219 0.107
biological adhesion GO:0022610 138 0.107
vesicle mediated transport GO:0016192 381 0.103
compound eye photoreceptor cell differentiation GO:0001751 140 0.102
programmed cell death GO:0012501 257 0.098
regionalization GO:0003002 416 0.093
cellular macromolecule localization GO:0070727 220 0.093
regulation of transport GO:0051049 181 0.093
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.088
regulation of response to stress GO:0080134 200 0.087
regulation of meiosis GO:0040020 3 0.084
photoreceptor cell development GO:0042461 96 0.077
central nervous system development GO:0007417 201 0.075
positive regulation of signaling GO:0023056 243 0.074
cell adhesion GO:0007155 136 0.072
regulation of photoreceptor cell differentiation GO:0046532 34 0.071
positive regulation of macromolecule metabolic process GO:0010604 405 0.071
organonitrogen compound metabolic process GO:1901564 318 0.069
female meiotic division GO:0007143 70 0.063
morphogenesis of an epithelium GO:0002009 276 0.062
regulation of developmental growth GO:0048638 174 0.062
negative regulation of response to stimulus GO:0048585 258 0.062
purine nucleotide metabolic process GO:0006163 146 0.056
photoreceptor cell differentiation GO:0046530 170 0.055
cell motility GO:0048870 251 0.054
regulation of protein metabolic process GO:0051246 256 0.054
regulation of anatomical structure morphogenesis GO:0022603 242 0.053
regulation of catalytic activity GO:0050790 185 0.052
negative regulation of cell communication GO:0010648 223 0.052
homeostatic process GO:0042592 199 0.049
protein localization GO:0008104 284 0.049
tube development GO:0035295 244 0.048
taxis GO:0042330 304 0.046
regulation of cellular component biogenesis GO:0044087 201 0.046
intracellular mrna localization GO:0008298 66 0.046
r7 cell differentiation GO:0045466 43 0.045
regulation of nervous system development GO:0051960 248 0.045
regulation of organelle organization GO:0033043 196 0.043
axonogenesis GO:0007409 290 0.042
ribonucleoside metabolic process GO:0009119 127 0.042
covalent chromatin modification GO:0016569 106 0.042
chromatin organization GO:0006325 207 0.042
amine metabolic process GO:0009308 12 0.040
protein complex biogenesis GO:0070271 201 0.040
negative regulation of molecular function GO:0044092 51 0.040
regulation of axonogenesis GO:0050770 32 0.040
axon development GO:0061564 297 0.040
protein phosphorylation GO:0006468 169 0.040
regulation of cell morphogenesis GO:0022604 163 0.039
protein localization to nucleus GO:0034504 55 0.039
organophosphate metabolic process GO:0019637 195 0.037
response to abiotic stimulus GO:0009628 341 0.036
multi organism behavior GO:0051705 175 0.035
protein modification by small protein conjugation or removal GO:0070647 106 0.035
positive regulation of cell communication GO:0010647 250 0.034
small molecule metabolic process GO:0044281 305 0.034
sensory perception GO:0007600 196 0.034
cell death GO:0008219 279 0.033
regulation of r7 cell differentiation GO:0045676 15 0.033
female meiosis chromosome segregation GO:0016321 33 0.033
appendage development GO:0048736 401 0.033
regulation of protein localization GO:0032880 76 0.033
stem cell fate commitment GO:0048865 25 0.033
regulation of cell shape GO:0008360 113 0.033
cellular amine metabolic process GO:0044106 12 0.032
instar larval development GO:0002168 55 0.030
regulation of molecular function GO:0065009 217 0.030
single organism cellular localization GO:1902580 180 0.030
meiotic cell cycle GO:0051321 171 0.029
cellular response to dna damage stimulus GO:0006974 223 0.029
purine nucleoside metabolic process GO:0042278 127 0.029
regulation of transferase activity GO:0051338 58 0.028
proteolysis GO:0006508 192 0.028
organelle fission GO:0048285 340 0.028
water homeostasis GO:0030104 3 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
chemotaxis GO:0006935 249 0.027
intracellular transport GO:0046907 228 0.027
camera type eye development GO:0043010 4 0.027
meiotic cell cycle process GO:1903046 132 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
heterocycle catabolic process GO:0046700 166 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
purine nucleoside catabolic process GO:0006152 112 0.026
regulation of establishment of protein localization GO:0070201 61 0.025
response to radiation GO:0009314 155 0.025
histone modification GO:0016570 106 0.025
nuclear division GO:0000280 332 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
response to light stimulus GO:0009416 124 0.025
protein modification by small protein conjugation GO:0032446 79 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.024
single organism behavior GO:0044708 391 0.024
positive regulation of molecular function GO:0044093 136 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
cellular protein localization GO:0034613 160 0.024
nucleoside metabolic process GO:0009116 127 0.023
metal ion homeostasis GO:0055065 44 0.023
negative regulation of transferase activity GO:0051348 18 0.023
neurological system process GO:0050877 358 0.023
positive regulation of transport GO:0051050 92 0.023
regulation of intracellular transport GO:0032386 64 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
chromatin modification GO:0016568 147 0.023
male gamete generation GO:0048232 201 0.022
response to lipopolysaccharide GO:0032496 4 0.022
regulation of intracellular protein transport GO:0033157 46 0.022
endocytosis GO:0006897 310 0.022
spermatid development GO:0007286 98 0.022
tissue morphogenesis GO:0048729 297 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
negative regulation of cellular component organization GO:0051129 108 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.021
ovarian follicle cell development GO:0030707 248 0.021
axis specification GO:0009798 167 0.021
protein ubiquitination GO:0016567 70 0.021
organic acid metabolic process GO:0006082 103 0.021
oocyte differentiation GO:0009994 145 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
hindbrain development GO:0030902 2 0.020
immune system process GO:0002376 347 0.020
spermatid differentiation GO:0048515 114 0.020
defense response GO:0006952 300 0.020
regulation of compound eye photoreceptor development GO:0045314 12 0.020
regulation of protein transport GO:0051223 57 0.020
regulation of notch signaling pathway GO:0008593 100 0.019
regulation of cytoplasmic transport GO:1903649 47 0.019
regulation of nuclear division GO:0051783 58 0.019
organic substance transport GO:0071702 257 0.019
ethanolamine containing compound metabolic process GO:0042439 4 0.019
purine containing compound metabolic process GO:0072521 155 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
death GO:0016265 284 0.019
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.019
cellular amino acid metabolic process GO:0006520 61 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
spermatogenesis GO:0007283 200 0.018
positive regulation of nucleotide catabolic process GO:0030813 46 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
growth GO:0040007 359 0.018
axonal defasciculation GO:0007414 12 0.018
response to oxygen containing compound GO:1901700 200 0.018
positive regulation of jun kinase activity GO:0043507 4 0.018
regulation of cell cycle GO:0051726 291 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
protein localization to organelle GO:0033365 82 0.017
secretion GO:0046903 109 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.017
positive regulation of r7 cell differentiation GO:0045678 7 0.017
maintenance of location GO:0051235 73 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
positive regulation of signal transduction GO:0009967 223 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
intracellular signal transduction GO:0035556 300 0.017
open tracheal system development GO:0007424 204 0.017
phagocytosis GO:0006909 215 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
peptidyl amino acid modification GO:0018193 105 0.016
regulation of cell division GO:0051302 72 0.016
head development GO:0060322 135 0.016
regulation of localization GO:0032879 275 0.016
hemopoiesis GO:0030097 46 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
regulation of organ morphogenesis GO:2000027 78 0.016
forebrain development GO:0030900 2 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
cellular ketone metabolic process GO:0042180 24 0.016
cell junction assembly GO:0034329 42 0.016
regulation of cellular response to stress GO:0080135 89 0.016
regulation of peptidase activity GO:0052547 39 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.015
respiratory system development GO:0060541 213 0.015
protein alkylation GO:0008213 43 0.015
pigmentation GO:0043473 75 0.015
single organism biosynthetic process GO:0044711 206 0.015
tube morphogenesis GO:0035239 191 0.015
developmental growth involved in morphogenesis GO:0060560 65 0.015
ion transport GO:0006811 145 0.015
response to wounding GO:0009611 94 0.015
wound healing GO:0042060 75 0.014
wing disc morphogenesis GO:0007472 344 0.014
cell division GO:0051301 248 0.014
nucleoside catabolic process GO:0009164 112 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of cell death GO:0010941 173 0.014
circulatory system process GO:0003013 37 0.014
multi organism reproductive behavior GO:0044705 121 0.014
response to other organism GO:0051707 293 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
notch signaling pathway GO:0007219 120 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
epithelial cell differentiation GO:0030855 322 0.014
wnt signaling pathway GO:0016055 98 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
ras protein signal transduction GO:0007265 88 0.013
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.013
endomembrane system organization GO:0010256 119 0.013
regulation of defense response GO:0031347 102 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
morphogenesis of embryonic epithelium GO:0016331 94 0.013
establishment of organelle localization GO:0051656 122 0.013
lateral inhibition GO:0046331 206 0.013
exocrine system development GO:0035272 162 0.013
gene silencing GO:0016458 138 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
release of sequestered calcium ion into cytosol GO:0051209 1 0.013
catabolic process GO:0009056 409 0.013
embryonic morphogenesis GO:0048598 206 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
ribonucleoside monophosphate metabolic process GO:0009161 51 0.013
epithelial cell development GO:0002064 274 0.013
single organism catabolic process GO:0044712 228 0.012
protein complex assembly GO:0006461 200 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
negative regulation of catalytic activity GO:0043086 42 0.012
negative regulation of cell death GO:0060548 81 0.012
immune effector process GO:0002252 98 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
localization of cell GO:0051674 257 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
regulation of cellular localization GO:0060341 136 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
mating GO:0007618 120 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
negative regulation of homeostatic process GO:0032845 2 0.012
regulation of apoptotic process GO:0042981 130 0.012
regulation of protein kinase activity GO:0045859 51 0.012
protein glycosylation GO:0006486 32 0.012
learning or memory GO:0007611 141 0.012
glycoprotein metabolic process GO:0009100 41 0.012
chromosome separation GO:0051304 42 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
oxoacid metabolic process GO:0043436 103 0.012
somatic muscle development GO:0007525 66 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
regulation of anatomical structure size GO:0090066 163 0.011
purine containing compound catabolic process GO:0072523 112 0.011
meiotic chromosome segregation GO:0045132 59 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
calcium ion transport GO:0006816 24 0.011
phosphorylation GO:0016310 294 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
compound eye cone cell fate commitment GO:0042676 5 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
motor neuron axon guidance GO:0008045 58 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of protein modification process GO:0031399 112 0.011
regulation of phosphatase activity GO:0010921 3 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
macromolecule methylation GO:0043414 45 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
establishment of localization in cell GO:0051649 402 0.011
regulation of mapk cascade GO:0043408 92 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.010
organelle localization GO:0051640 148 0.010
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
rho protein signal transduction GO:0007266 14 0.010
regulation of embryonic cell shape GO:0016476 30 0.010
negative regulation of organelle organization GO:0010639 56 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010

sdk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.016
urinary system disease DOID:18 0 0.015
organ system cancer DOID:0050686 0 0.014