Drosophila melanogaster

162 known processes

scb (Dmel_CG8095)

scab

(Aliases: vol,alphaPS3,E(sev-cycE)[e93],alphaInt3,Vol,aPS3,alpha[[PS3]],Dm0620,E(Sev-CycE)E93,beta[[PS3],CG8095,CT21280,PS3,Dmel\CG8095,CT36929,alpha-PS3,l(2)01288)

scb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of synapse organization GO:0050807 110 0.993
synaptic growth at neuromuscular junction GO:0051124 119 0.980
single organism behavior GO:0044708 391 0.968
ameboidal type cell migration GO:0001667 151 0.960
Human Fly
regulation of cellular component biogenesis GO:0044087 201 0.954
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.945
hindgut morphogenesis GO:0007442 58 0.942
imaginal disc derived appendage morphogenesis GO:0035114 395 0.930
Fly
regulation of synapse assembly GO:0051963 94 0.927
tube development GO:0035295 244 0.922
Human
behavioral response to ethanol GO:0048149 49 0.912
epithelial cell migration GO:0010631 148 0.899
Fly
dorsal closure GO:0007391 79 0.896
morphogenesis of embryonic epithelium GO:0016331 94 0.887
epithelium migration GO:0090132 148 0.887
Fly
tissue migration GO:0090130 155 0.868
Fly
regulation of phosphate metabolic process GO:0019220 210 0.857
Human
digestive tract development GO:0048565 149 0.847
Human
hemocyte migration GO:0035099 19 0.840
Fly
embryonic hemopoiesis GO:0035162 26 0.830
Fly
regulation of cell morphogenesis GO:0022604 163 0.822
Fly
synaptic transmission GO:0007268 288 0.821
cell division GO:0051301 248 0.799
cell cell junction organization GO:0045216 55 0.799
oocyte development GO:0048599 124 0.783
malpighian tubule development GO:0072002 64 0.781
cognition GO:0050890 141 0.774
vesicle mediated transport GO:0016192 381 0.761
imaginal disc derived appendage development GO:0048737 399 0.746
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.733
chemotaxis GO:0006935 249 0.726
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.717
developmental maturation GO:0021700 172 0.712
neuromuscular junction development GO:0007528 149 0.711
embryonic morphogenesis GO:0048598 206 0.703
digestive system development GO:0055123 149 0.702
Human
synapse assembly GO:0007416 143 0.700
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.690
regulation of anatomical structure morphogenesis GO:0022603 242 0.688
Fly
muscle attachment GO:0016203 36 0.674
Fly
regulation of filopodium assembly GO:0051489 24 0.663
wing disc morphogenesis GO:0007472 344 0.657
Fly
regulation of multicellular organismal development GO:2000026 414 0.642
malpighian tubule morphogenesis GO:0007443 44 0.629
regulation of tube architecture open tracheal system GO:0035152 68 0.624
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.613
Human
response to ethanol GO:0045471 59 0.605
negative regulation of cellular metabolic process GO:0031324 382 0.594
establishment of synaptic vesicle localization GO:0097480 50 0.583
post embryonic appendage morphogenesis GO:0035120 385 0.561
Fly
axonogenesis GO:0007409 290 0.554
cell growth GO:0016049 108 0.551
embryonic hindgut morphogenesis GO:0048619 48 0.542
appendage development GO:0048736 401 0.524
Fly
regulation of wound healing GO:0061041 13 0.523
regulation of cellular protein metabolic process GO:0032268 243 0.520
appendage morphogenesis GO:0035107 397 0.519
Fly
negative regulation of synapse assembly GO:0051964 39 0.515
intracellular signal transduction GO:0035556 300 0.512
Mouse
regulation of developmental growth GO:0048638 174 0.504
cell junction assembly GO:0034329 42 0.502
regulation of synapse structure and activity GO:0050803 128 0.498
negative regulation of rho protein signal transduction GO:0035024 1 0.498
neurological system process GO:0050877 358 0.495
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.487
taxis GO:0042330 304 0.484
synapse organization GO:0050808 196 0.477
digestive tract morphogenesis GO:0048546 127 0.470
Human
skin development GO:0043588 65 0.470
initiation of dorsal closure GO:0007392 12 0.469
filopodium assembly GO:0046847 33 0.465
learning GO:0007612 75 0.458
positive regulation of phosphorus metabolic process GO:0010562 139 0.457
Human
mesoderm development GO:0007498 78 0.432
Human
regulation of phosphorylation GO:0042325 147 0.432
embryonic ectodermal digestive tract development GO:0048611 4 0.429
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.424
regulation of cell projection organization GO:0031344 92 0.421
adherens junction assembly GO:0034333 11 0.419
stem cell proliferation GO:0072089 88 0.418
apoptotic cell clearance GO:0043277 14 0.417
regulation of neuron projection development GO:0010975 69 0.410
neurotransmitter secretion GO:0007269 35 0.408
renal tubule development GO:0061326 64 0.407
g protein coupled receptor signaling pathway GO:0007186 136 0.404
single organism cellular localization GO:1902580 180 0.400
Human
regulation of growth GO:0040008 233 0.400
regulation of cell differentiation GO:0045595 302 0.397
Mouse
regulation of protein metabolic process GO:0051246 256 0.395
spermatid differentiation GO:0048515 114 0.394
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.375
regulation of nervous system development GO:0051960 248 0.374
negative regulation of cellular component organization GO:0051129 108 0.369
regulation of cell development GO:0060284 215 0.367
organelle fission GO:0048285 340 0.362
single organismal cell cell adhesion GO:0016337 45 0.359
Human Mouse
imaginal disc derived leg morphogenesis GO:0007480 80 0.356
chemosensory behavior GO:0007635 106 0.355
cell proliferation GO:0008283 299 0.353
Human Mouse
establishment of localization in cell GO:0051649 402 0.353
regulation of immune response GO:0050776 118 0.353
cell migration GO:0016477 238 0.350
regulation of dendrite development GO:0050773 37 0.346
regulation of protein kinase activity GO:0045859 51 0.345
regulation of embryonic development GO:0045995 68 0.342
hematopoietic or lymphoid organ development GO:0048534 57 0.337
Mouse Fly
response to other organism GO:0051707 293 0.333
Mouse
renal tubule morphogenesis GO:0061333 44 0.326
positive regulation of cellular protein metabolic process GO:0032270 118 0.325
axon guidance GO:0007411 233 0.323
negative regulation of biosynthetic process GO:0009890 277 0.319
regulation of cellular ketone metabolic process GO:0010565 3 0.316
enzyme linked receptor protein signaling pathway GO:0007167 179 0.314
Mouse
cell projection assembly GO:0030031 94 0.314
establishment of organelle localization GO:0051656 122 0.313
negative regulation of transcription dna templated GO:0045892 237 0.311
positive regulation of protein secretion GO:0050714 9 0.310
gastrulation involving germ band extension GO:0010004 36 0.307
positive regulation of transcription dna templated GO:0045893 266 0.303
cell junction organization GO:0034330 57 0.300
motor neuron axon guidance GO:0008045 58 0.296
secretion by cell GO:0032940 101 0.292
memory GO:0007613 94 0.289
positive regulation of cellular component organization GO:0051130 156 0.289
multi organism behavior GO:0051705 175 0.288
imaginal disc derived wing morphogenesis GO:0007476 337 0.288
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.284
border follicle cell migration GO:0007298 113 0.283
Fly
immune system process GO:0002376 347 0.282
Human Mouse Fly
regulation of response to external stimulus GO:0032101 115 0.280
response to temperature stimulus GO:0009266 106 0.279
central nervous system development GO:0007417 201 0.275
Mouse
phosphorylation GO:0016310 294 0.275
growth GO:0040007 359 0.274
neuroblast proliferation GO:0007405 74 0.273
male gamete generation GO:0048232 201 0.269
lipid metabolic process GO:0006629 121 0.266
adherens junction organization GO:0034332 27 0.265
regulation of lipid kinase activity GO:0043550 2 0.265
regulation of cell shape GO:0008360 113 0.264
Fly
positive regulation of cell motility GO:2000147 3 0.262
exocytosis GO:0006887 28 0.260
salivary gland development GO:0007431 162 0.260
oocyte differentiation GO:0009994 145 0.258
regulation of cell cycle GO:0051726 291 0.256
positive regulation of cell migration GO:0030335 2 0.254
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.243
nuclear division GO:0000280 332 0.243
synaptic vesicle localization GO:0097479 53 0.242
anterior posterior pattern specification GO:0009952 136 0.240
single organism biosynthetic process GO:0044711 206 0.240
establishment of protein localization GO:0045184 163 0.239
small molecule metabolic process GO:0044281 305 0.237
ovarian follicle cell migration GO:0007297 121 0.236
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.235
negative regulation of developmental process GO:0051093 201 0.235
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.233
regulation of axonogenesis GO:0050770 32 0.230
spermatid development GO:0007286 98 0.230
actin filament based process GO:0030029 220 0.224
Fly
learning or memory GO:0007611 141 0.224
paracrine signaling GO:0038001 7 0.223
regulation of organelle organization GO:0033043 196 0.223
Fly
cellular macromolecule localization GO:0070727 220 0.222
Human
multicellular organismal homeostasis GO:0048871 41 0.221
Mouse Fly
positive regulation of filopodium assembly GO:0051491 15 0.220
hemopoiesis GO:0030097 46 0.218
Mouse Fly
melanotic encapsulation of foreign target GO:0035011 30 0.217
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.216
oocyte axis specification GO:0007309 108 0.214
positive regulation of cellular component biogenesis GO:0044089 80 0.214
regulation of cell death GO:0010941 173 0.213
ventral cord development GO:0007419 16 0.213
regulation of epithelial cell proliferation GO:0050678 4 0.212
developmental growth GO:0048589 280 0.210
determination of digestive tract left right asymmetry GO:0071907 6 0.210
aminoglycan biosynthetic process GO:0006023 11 0.205
muscle tissue development GO:0060537 30 0.205
signal transduction by phosphorylation GO:0023014 107 0.205
ectodermal digestive tract morphogenesis GO:0048567 7 0.203
olfactory behavior GO:0042048 97 0.201
amine metabolic process GO:0009308 12 0.200
endocytosis GO:0006897 310 0.198
cellular lipid metabolic process GO:0044255 83 0.197
response to wounding GO:0009611 94 0.197
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.197
associative learning GO:0008306 65 0.194
pericardium morphogenesis GO:0003344 2 0.194
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.194
regulation of cellular amino acid metabolic process GO:0006521 0 0.193
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.193
regionalization GO:0003002 416 0.193
Fly
regulation of mitotic cell cycle GO:0007346 190 0.191
positive regulation of cellular amine metabolic process GO:0033240 0 0.191
oocyte microtubule cytoskeleton organization GO:0016325 35 0.189
embryonic development via the syncytial blastoderm GO:0001700 148 0.189
regulation of transferase activity GO:0051338 58 0.187
regulation of protein modification process GO:0031399 112 0.186
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.183
cellular amine metabolic process GO:0044106 12 0.180
mesenchymal cell differentiation GO:0048762 1 0.180
neuron death GO:0070997 27 0.180
cellular amino acid metabolic process GO:0006520 61 0.178
adult behavior GO:0030534 137 0.176
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.174
circulatory system development GO:0072359 82 0.174
dna metabolic process GO:0006259 227 0.173
purine ribonucleotide metabolic process GO:0009150 145 0.173
homeostatic process GO:0042592 199 0.172
Mouse Fly
immune effector process GO:0002252 98 0.172
Human Mouse
regulation of kinase activity GO:0043549 53 0.171
regulation of neuron differentiation GO:0045664 103 0.170
transmembrane transport GO:0055085 139 0.170
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.170
urogenital system development GO:0001655 72 0.169
tripartite regional subdivision GO:0007351 103 0.168
positive regulation of signaling GO:0023056 243 0.165
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.165
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.163
response to external biotic stimulus GO:0043207 293 0.163
Mouse
neuron projection guidance GO:0097485 241 0.161
reactive oxygen species metabolic process GO:0072593 22 0.159
positive regulation of macromolecule metabolic process GO:0010604 405 0.159
negative regulation of cell communication GO:0010648 223 0.158
Mouse
erbb signaling pathway GO:0038127 58 0.158
Mouse
response to heat GO:0009408 63 0.155
regulation of cellular localization GO:0060341 136 0.154
gland morphogenesis GO:0022612 145 0.152
Fly
positive regulation of catalytic activity GO:0043085 118 0.152
Human
stem cell differentiation GO:0048863 117 0.151
single organism cell adhesion GO:0098602 47 0.149
Human Mouse
protein localization GO:0008104 284 0.149
Human Fly
regulation of cell proliferation GO:0042127 163 0.148
Human Mouse
blastoderm segmentation GO:0007350 159 0.147
mesoderm morphogenesis GO:0048332 22 0.146
Human
positive regulation of developmental process GO:0051094 143 0.146
Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.146
cell cell adhesion mediated by integrin GO:0033631 1 0.146
carbohydrate derivative biosynthetic process GO:1901137 85 0.146
cytokinesis GO:0000910 90 0.146
regulation of intracellular signal transduction GO:1902531 236 0.146
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.145
peptidyl tyrosine modification GO:0018212 24 0.144
positive regulation of protein localization to plasma membrane GO:1903078 3 0.142
apoptotic process GO:0006915 159 0.141
response to radiation GO:0009314 155 0.141
death GO:0016265 284 0.139
positive regulation of growth GO:0045927 75 0.138
peripheral nervous system development GO:0007422 52 0.137
organonitrogen compound metabolic process GO:1901564 318 0.135
regulation of cellular component size GO:0032535 98 0.135
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.134
defense response GO:0006952 300 0.133
Mouse
mapk cascade GO:0000165 107 0.133
regulation of tube size open tracheal system GO:0035151 43 0.129
columnar cuboidal epithelial cell development GO:0002066 249 0.129
Fly
negative regulation of signaling GO:0023057 219 0.129
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.129
regulation of immune system process GO:0002682 176 0.128
Mouse
phagocytosis GO:0006909 215 0.128
regulation of cell cell adhesion GO:0022407 21 0.128
Mouse
regulation of epithelial cell migration GO:0010632 12 0.126
peptidyl amino acid modification GO:0018193 105 0.126
dorsal closure spreading of leading edge cells GO:0007395 4 0.126
positive regulation of protein metabolic process GO:0051247 128 0.125
epithelial cell development GO:0002064 274 0.123
Fly
cellular ketone metabolic process GO:0042180 24 0.123
divalent inorganic cation homeostasis GO:0072507 29 0.123
chorion containing eggshell formation GO:0007304 105 0.123
negative regulation of phosphorylation GO:0042326 35 0.123
protein phosphorylation GO:0006468 169 0.121
positive regulation of protein modification process GO:0031401 58 0.121
response to transforming growth factor beta GO:0071559 18 0.119
peptidyl tyrosine phosphorylation GO:0018108 24 0.118
heart morphogenesis GO:0003007 32 0.118
immune response GO:0006955 246 0.118
Human
cellular catabolic process GO:0044248 372 0.118
response to light stimulus GO:0009416 124 0.115
anterior midgut ectodermal morphogenesis GO:0007441 4 0.115
embryonic pattern specification GO:0009880 174 0.114
dendrite morphogenesis GO:0048813 199 0.113
endodermal cell differentiation GO:0035987 3 0.113
Human
actin filament organization GO:0007015 126 0.113
Fly
gastrulation with mouth forming first GO:0001703 36 0.113
leg disc morphogenesis GO:0007478 80 0.112
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.112
maintenance of location GO:0051235 73 0.112
Fly
regulation of localization GO:0032879 275 0.111
spermatogenesis GO:0007283 200 0.111
neuroblast division GO:0055057 35 0.111
cell maturation GO:0048469 144 0.110
negative regulation of growth GO:0045926 84 0.110
multicellular organismal aging GO:0010259 140 0.109
axon development GO:0061564 297 0.108
gliogenesis GO:0042063 80 0.108
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.108
dorsal closure amnioserosa morphology change GO:0046664 7 0.107
response to biotic stimulus GO:0009607 294 0.107
Mouse
anterior posterior axis specification embryo GO:0008595 103 0.107
regulation of mitosis GO:0007088 56 0.106
positive regulation of cell projection organization GO:0031346 29 0.105
negative regulation of response to stimulus GO:0048585 258 0.105
Mouse
positive regulation of nervous system development GO:0051962 69 0.104
regulation of nuclear division GO:0051783 58 0.103
positive regulation of rna biosynthetic process GO:1902680 266 0.103
negative regulation of cellular protein metabolic process GO:0032269 85 0.103
negative regulation of gene expression GO:0010629 387 0.102
positive regulation of hydrolase activity GO:0051345 78 0.102
Human
embryonic axis specification GO:0000578 107 0.102
embryonic organ development GO:0048568 50 0.102
Mouse Fly
negative regulation of programmed cell death GO:0043069 72 0.102
positive regulation of cell cell adhesion GO:0022409 9 0.101
Mouse
organic hydroxy compound metabolic process GO:1901615 83 0.101
negative regulation of mitotic cell cycle GO:0045930 109 0.100
imaginal disc derived wing hair organization GO:0035317 45 0.099
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.098
receptor clustering GO:0043113 3 0.098
Human
cardiovascular system development GO:0072358 82 0.096
regulation of catalytic activity GO:0050790 185 0.096
Human
synaptic vesicle exocytosis GO:0016079 16 0.096
response to oxygen containing compound GO:1901700 200 0.096
wing disc pattern formation GO:0035222 66 0.095
regulation of neurotransmitter levels GO:0001505 38 0.094
response to alcohol GO:0097305 95 0.094
regulation of cell projection assembly GO:0060491 30 0.094
establishment of glial blood brain barrier GO:0060857 14 0.094
hindgut development GO:0061525 58 0.094
regulation of protein serine threonine kinase activity GO:0071900 25 0.093
mitotic nuclear division GO:0007067 213 0.093
regulation of anatomical structure size GO:0090066 163 0.093
negative regulation of nucleic acid templated transcription GO:1903507 240 0.092
germ band extension GO:0007377 11 0.092
dna biosynthetic process GO:0071897 24 0.092
hemocyte development GO:0007516 7 0.091
glial cell differentiation GO:0010001 35 0.090
Mouse
localization of cell GO:0051674 257 0.090
regulation of chemotaxis GO:0050920 12 0.090
epidermis development GO:0008544 65 0.090
negative regulation of apoptotic process GO:0043066 63 0.090
cellular protein modification process GO:0006464 438 0.090
axon regeneration GO:0031103 8 0.089
regulation of apoptotic process GO:0042981 130 0.089
collateral sprouting GO:0048668 3 0.089
myoblast fusion GO:0007520 43 0.089
positive regulation of molecular function GO:0044093 136 0.088
Human
myoblast proliferation GO:0051450 3 0.088
positive regulation of cell communication GO:0010647 250 0.088
Mouse
striated muscle tissue development GO:0014706 27 0.088
male mating behavior GO:0060179 70 0.088
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.086
camp biosynthetic process GO:0006171 17 0.086
transcription from rna polymerase ii promoter GO:0006366 368 0.085
maintenance of cell polarity GO:0030011 18 0.085
regulation of molecular function GO:0065009 217 0.085
Human
segmentation GO:0035282 207 0.085
regulation of vesicle mediated transport GO:0060627 59 0.084
negative regulation of phosphorus metabolic process GO:0010563 45 0.084
regulation of protein phosphorylation GO:0001932 64 0.083
olfactory learning GO:0008355 56 0.083
anatomical structure homeostasis GO:0060249 97 0.082
Mouse Fly
regulation of cell division GO:0051302 72 0.081
catabolic process GO:0009056 409 0.081
substrate dependent cell migration GO:0006929 3 0.080
Human Mouse
negative regulation of autophagy GO:0010507 16 0.080
cellular response to growth factor stimulus GO:0071363 30 0.080
dendrite development GO:0016358 204 0.080
positive regulation of response to stimulus GO:0048584 323 0.079
Mouse
regulation of response to wounding GO:1903034 19 0.079
carboxylic acid metabolic process GO:0019752 92 0.079
response to abiotic stimulus GO:0009628 341 0.079
leg disc development GO:0035218 92 0.078
regulation of response to stress GO:0080134 200 0.078
unidimensional cell growth GO:0009826 15 0.078
ras protein signal transduction GO:0007265 88 0.077
gtp metabolic process GO:0046039 72 0.077
regulation of embryonic cell shape GO:0016476 30 0.077
cell adhesion GO:0007155 136 0.077
innate immune response GO:0045087 144 0.077
cytoplasmic transport GO:0016482 130 0.076
defense response to other organism GO:0098542 225 0.076
Mouse
anterior posterior axis specification GO:0009948 109 0.075
cell death GO:0008219 279 0.075
salivary gland morphogenesis GO:0007435 145 0.074
Fly
regulation of protein tyrosine kinase activity GO:0061097 9 0.074
regulation of neurogenesis GO:0050767 158 0.073
positive regulation of immune response GO:0050778 63 0.073
protein transport GO:0015031 155 0.071
negative regulation of intracellular signal transduction GO:1902532 57 0.071
organic substance transport GO:0071702 257 0.071
ribonucleotide metabolic process GO:0009259 145 0.071
formation of primary germ layer GO:0001704 24 0.068
Human
heart development GO:0007507 82 0.068
organophosphate metabolic process GO:0019637 195 0.067
aging GO:0007568 143 0.066
cuticle development GO:0042335 86 0.066
negative regulation of protein phosphorylation GO:0001933 17 0.066
purine ribonucleotide catabolic process GO:0009154 109 0.066
regulation of transport GO:0051049 181 0.066
epidermal growth factor receptor signaling pathway GO:0007173 58 0.065
Mouse
renal filtration GO:0097205 7 0.065
stem cell division GO:0017145 69 0.065
membrane organization GO:0061024 112 0.065
Human
epithelial cell cell adhesion GO:0090136 6 0.064
positive regulation of cell differentiation GO:0045597 64 0.064
Mouse
cell chemotaxis GO:0060326 6 0.064
Mouse
positive regulation of apoptotic process GO:0043065 47 0.064
cellular protein localization GO:0034613 160 0.063
Human
negative regulation of cell death GO:0060548 81 0.063
neuromuscular synaptic transmission GO:0007274 67 0.063
immune response regulating signaling pathway GO:0002764 2 0.063
skeletal muscle organ development GO:0060538 48 0.063
Fly
cellular response to radiation GO:0071478 52 0.062
tube morphogenesis GO:0035239 191 0.062
Human
positive regulation of cell proliferation GO:0008284 47 0.062
Mouse
oocyte anterior posterior axis specification GO:0007314 72 0.061
dorsal ventral pattern formation GO:0009953 133 0.061
regulation of purine nucleotide metabolic process GO:1900542 62 0.061
negative regulation of protein metabolic process GO:0051248 85 0.061
blood circulation GO:0008015 26 0.061
negative regulation of kinase activity GO:0033673 16 0.060
neurotransmitter transport GO:0006836 37 0.060
mitochondrion organization GO:0007005 65 0.060
intraspecies interaction between organisms GO:0051703 4 0.060
nucleoside phosphate metabolic process GO:0006753 162 0.060
positive regulation of gene expression GO:0010628 290 0.060
nucleocytoplasmic transport GO:0006913 72 0.059
cell substrate adhesion GO:0031589 10 0.059
Human
endoderm formation GO:0001706 3 0.058
Human
cell motility GO:0048870 251 0.058
micropyle formation GO:0046844 4 0.058
meiotic cytokinesis GO:0033206 33 0.058
positive regulation of biosynthetic process GO:0009891 316 0.058
regulation of small gtpase mediated signal transduction GO:0051056 93 0.058
cardiac cell fate determination GO:0060913 3 0.058
social behavior GO:0035176 4 0.058
gland development GO:0048732 191 0.057
positive regulation of rna metabolic process GO:0051254 271 0.057
regulation of cell junction assembly GO:1901888 2 0.057
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.056
small gtpase mediated signal transduction GO:0007264 88 0.056
positive regulation of wound healing GO:0090303 12 0.056
anterior malpighian tubule development GO:0061327 12 0.056
response to growth factor GO:0070848 31 0.056
single organism catabolic process GO:0044712 228 0.056
organonitrogen compound biosynthetic process GO:1901566 117 0.055
larval development GO:0002164 104 0.055
protein secretion GO:0009306 45 0.055
secretion GO:0046903 109 0.055
epithelial cell proliferation GO:0050673 15 0.055
secondary metabolic process GO:0019748 75 0.055
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.054
multi organism reproductive behavior GO:0044705 121 0.054
pole plasm assembly GO:0007315 61 0.054
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.054
Fly
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.054
regulation of cysteine type endopeptidase activity GO:2000116 27 0.054
lipid localization GO:0010876 54 0.053
regulation of cell substrate adhesion GO:0010810 2 0.053
mating GO:0007618 120 0.053
regulation of synaptic transmission GO:0050804 69 0.053
embryonic anterior midgut ectodermal morphogenesis GO:0048615 4 0.053
cell type specific apoptotic process GO:0097285 38 0.053
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.053
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.052
regulation of reproductive process GO:2000241 54 0.052
axon extension GO:0048675 32 0.052
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.052
establishment or maintenance of cell polarity GO:0007163 167 0.052
apical junction assembly GO:0043297 32 0.051
protein modification process GO:0036211 438 0.051
positive regulation of phosphate metabolic process GO:0045937 139 0.051
Human
hematopoietic progenitor cell differentiation GO:0002244 1 0.050
pigment metabolic process GO:0042440 84 0.050
stress activated mapk cascade GO:0051403 52 0.049
negative regulation of signal transduction GO:0009968 206 0.049
Mouse
positive regulation of synapse assembly GO:0051965 29 0.049
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.049
Mouse
nuclear transport GO:0051169 72 0.048
regulation of lipid metabolic process GO:0019216 15 0.048
neuronal stem cell division GO:0036445 35 0.048
regulation of nucleocytoplasmic transport GO:0046822 35 0.048
positive regulation of mapk cascade GO:0043410 63 0.047
regulation of epithelial cell differentiation GO:0030856 4 0.047
regulation of neurotransmitter secretion GO:0046928 14 0.047
negative regulation of developmental growth GO:0048640 64 0.047
negative regulation of rna metabolic process GO:0051253 251 0.047
negative regulation of ras protein signal transduction GO:0046580 13 0.047
metal ion transport GO:0030001 74 0.047
positive regulation of nucleic acid templated transcription GO:1903508 266 0.047
establishment of vesicle localization GO:0051650 51 0.047
oocyte construction GO:0007308 112 0.046
limb development GO:0060173 1 0.046
negative regulation of phosphate metabolic process GO:0045936 45 0.046

scb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.431
cancer DOID:162 0 0.236
organ system cancer DOID:0050686 0 0.236
disease of anatomical entity DOID:7 0 0.078
Human
cardiovascular system disease DOID:1287 0 0.071
vascular disease DOID:178 0 0.048