Drosophila melanogaster

12 known processes

b (Dmel_CG7811)

black

(Aliases: anon-34Db,CG7811,cDNA 1,DmGad2,Dmel\CG7811,GAD[[2]],DGad2,BG:DS00941.5,Gad2)

b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.170
Zebrafish Fly
response to other organism GO:0051707 293 0.088
response to fungus GO:0009620 50 0.084
single organism biosynthetic process GO:0044711 206 0.071
Fly
response to abiotic stimulus GO:0009628 341 0.062
endocytosis GO:0006897 310 0.057
pigment metabolic process GO:0042440 84 0.050
response to biotic stimulus GO:0009607 294 0.048
axis specification GO:0009798 167 0.048
small molecule metabolic process GO:0044281 305 0.047
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.047
Zebrafish Fly
defense response to other organism GO:0098542 225 0.045
phagocytosis GO:0006909 215 0.045
organic acid metabolic process GO:0006082 103 0.044
Fly
response to bacterium GO:0009617 198 0.043
vesicle mediated transport GO:0016192 381 0.042
response to external biotic stimulus GO:0043207 293 0.041
negative regulation of cellular metabolic process GO:0031324 382 0.040
indole containing compound biosynthetic process GO:0042435 4 0.040
cytolysis in other organism GO:0051715 1 0.039
immune response GO:0006955 246 0.036
immune system process GO:0002376 347 0.035
killing of cells of other organism GO:0031640 1 0.035
oxoacid metabolic process GO:0043436 103 0.034
Fly
regulation of multicellular organismal development GO:2000026 414 0.032
response to temperature stimulus GO:0009266 106 0.032
pigment biosynthetic process GO:0046148 36 0.031
regulation of transport GO:0051049 181 0.031
positive regulation of lipid storage GO:0010884 4 0.031
positive regulation of response to stimulus GO:0048584 323 0.030
detection of stimulus GO:0051606 156 0.030
developmental pigmentation GO:0048066 68 0.030
positive regulation of signaling GO:0023056 243 0.029
regionalization GO:0003002 416 0.028
pigmentation GO:0043473 75 0.028
defense response to fungus GO:0050832 48 0.028
cellular amino acid metabolic process GO:0006520 61 0.027
Fly
actin cytoskeleton organization GO:0030036 206 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
organic substance transport GO:0071702 257 0.027
catabolic process GO:0009056 409 0.026
Fly
protein maturation GO:0051604 71 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
response to organic substance GO:0010033 284 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
nucleotide metabolic process GO:0009117 161 0.025
dorsal ventral axis specification GO:0009950 66 0.025
negative regulation of biosynthetic process GO:0009890 277 0.024
male courtship behavior GO:0008049 63 0.024
homeostatic process GO:0042592 199 0.024
cellular catabolic process GO:0044248 372 0.024
Fly
organic substance catabolic process GO:1901575 308 0.023
Fly
regulation of phosphate metabolic process GO:0019220 210 0.023
defense response GO:0006952 300 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
protein complex biogenesis GO:0070271 201 0.023
macromolecular complex assembly GO:0065003 256 0.023
heterocycle catabolic process GO:0046700 166 0.023
negative regulation of gene expression GO:0010629 387 0.022
wing disc morphogenesis GO:0007472 344 0.022
cholesterol transport GO:0030301 2 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
body morphogenesis GO:0010171 2 0.022
intracellular signal transduction GO:0035556 300 0.022
male meiosis GO:0007140 52 0.021
immune effector process GO:0002252 98 0.021
cell death GO:0008219 279 0.021
positive regulation of cell communication GO:0010647 250 0.021
gland development GO:0048732 191 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
Fly
peptide metabolic process GO:0006518 80 0.021
protein processing GO:0016485 68 0.021
single organism behavior GO:0044708 391 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
regulation of catalytic activity GO:0050790 185 0.020
organophosphate metabolic process GO:0019637 195 0.020
cell proliferation GO:0008283 299 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
defense response to bacterium GO:0042742 178 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
secondary metabolite biosynthetic process GO:0044550 24 0.019
response to lipopolysaccharide GO:0032496 4 0.019
regulation of localization GO:0032879 275 0.019
actin filament based process GO:0030029 220 0.019
cellular response to organic substance GO:0071310 132 0.019
eye pigmentation GO:0048069 43 0.019
embryonic pattern specification GO:0009880 174 0.019
single organism catabolic process GO:0044712 228 0.019
Fly
dorsal ventral pattern formation GO:0009953 133 0.019
mitotic nuclear division GO:0007067 213 0.019
camera type eye development GO:0043010 4 0.019
eye morphogenesis GO:0048592 260 0.018
positive regulation of signal transduction GO:0009967 223 0.018
cellular amine metabolic process GO:0044106 12 0.018
negative regulation of cell communication GO:0010648 223 0.018
androgen metabolic process GO:0008209 1 0.018
humoral immune response GO:0006959 117 0.017
regulation of immune system process GO:0002682 176 0.017
regulation of molecular function GO:0065009 217 0.017
protein phosphorylation GO:0006468 169 0.017
salivary gland morphogenesis GO:0007435 145 0.017
phosphorylation GO:0016310 294 0.016
eye development GO:0001654 323 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
nuclear division GO:0000280 332 0.016
death GO:0016265 284 0.016
gland morphogenesis GO:0022612 145 0.016
negative regulation of transcription dna templated GO:0045892 237 0.016
response to heat GO:0009408 63 0.016
sensory organ morphogenesis GO:0090596 260 0.016
male mating behavior GO:0060179 70 0.016
response to decreased oxygen levels GO:0036293 58 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
cell division GO:0051301 248 0.016
tissue death GO:0016271 102 0.016
cellular response to biotic stimulus GO:0071216 4 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
growth GO:0040007 359 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
amine metabolic process GO:0009308 12 0.015
positive regulation of molecular function GO:0044093 136 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
organelle fission GO:0048285 340 0.015
protein modification process GO:0036211 438 0.015
maintenance of location GO:0051235 73 0.015
anatomical structure homeostasis GO:0060249 97 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.014
response to nitrogen compound GO:1901698 90 0.014
response to oxygen containing compound GO:1901700 200 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
response to extracellular stimulus GO:0009991 116 0.014
macromolecule catabolic process GO:0009057 161 0.014
adult behavior GO:0030534 137 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
Fly
organic cyclic compound catabolic process GO:1901361 168 0.014
appendage development GO:0048736 401 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
mating GO:0007618 120 0.014
compound eye development GO:0048749 307 0.014
forebrain development GO:0030900 2 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
segmentation GO:0035282 207 0.014
cellular protein modification process GO:0006464 438 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
actin filament organization GO:0007015 126 0.014
positive regulation of developmental process GO:0051094 143 0.014
kidney development GO:0001822 3 0.014
reproductive behavior GO:0019098 122 0.014
regulation of defense response GO:0031347 102 0.013
programmed cell death GO:0012501 257 0.013
regulation of organelle organization GO:0033043 196 0.013
response to nutrient levels GO:0031667 114 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of cell cycle GO:0051726 291 0.013
positive regulation of cell motility GO:2000147 3 0.013
determination of adult lifespan GO:0008340 137 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
secondary metabolic process GO:0019748 75 0.013
purine containing compound metabolic process GO:0072521 155 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
sensory perception GO:0007600 196 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
salivary gland histolysis GO:0035070 88 0.013
regulation of multi organism process GO:0043900 131 0.013
blastoderm segmentation GO:0007350 159 0.013
appendage morphogenesis GO:0035107 397 0.013
connective tissue development GO:0061448 3 0.013
regulation of protein metabolic process GO:0051246 256 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
aromatic compound catabolic process GO:0019439 166 0.013
negative regulation of signaling GO:0023057 219 0.013
innate immune response GO:0045087 144 0.013
circadian rhythm GO:0007623 105 0.013
organophosphate catabolic process GO:0046434 112 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
regulation of response to stress GO:0080134 200 0.012
protein complex assembly GO:0006461 200 0.012
multicellular organismal aging GO:0010259 140 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
developmental programmed cell death GO:0010623 138 0.012
cellular response to radiation GO:0071478 52 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
regulation of response to external stimulus GO:0032101 115 0.012
single organism intracellular transport GO:1902582 207 0.012
intracellular transport GO:0046907 228 0.012
regulation of cell differentiation GO:0045595 302 0.012
tube morphogenesis GO:0035239 191 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
aging GO:0007568 143 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
olfactory behavior GO:0042048 97 0.012
Fly
regulation of cellular catabolic process GO:0031329 157 0.012
proteolysis GO:0006508 192 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
regulation of cell development GO:0060284 215 0.012
response to radiation GO:0009314 155 0.012
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.012
negative regulation of signal transduction GO:0009968 206 0.012
taxis GO:0042330 304 0.011
histolysis GO:0007559 102 0.011
autophagic cell death GO:0048102 83 0.011
neutral lipid catabolic process GO:0046461 3 0.011
response to alcohol GO:0097305 95 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
response to organic cyclic compound GO:0014070 89 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of sterol transport GO:0032371 1 0.011
rhythmic process GO:0048511 106 0.011
multi organism behavior GO:0051705 175 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
positive regulation of cell migration GO:0030335 2 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
regulation of lipid transport GO:0032368 3 0.011
response to monosaccharide GO:0034284 4 0.011
regulation of catabolic process GO:0009894 170 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
establishment of localization in cell GO:0051649 402 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
cellular lipid metabolic process GO:0044255 83 0.011
salivary gland development GO:0007431 162 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
response to oxygen levels GO:0070482 59 0.011
rna processing GO:0006396 147 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
synapse assembly GO:0007416 143 0.011
Fly
molting cycle chitin based cuticle GO:0007591 56 0.011
response to hexose GO:0009746 3 0.011
detection of chemical stimulus GO:0009593 93 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
positive regulation of immune system process GO:0002684 68 0.011
cellular ketone metabolic process GO:0042180 24 0.011
mrna metabolic process GO:0016071 124 0.011
carbohydrate metabolic process GO:0005975 82 0.011
nucleoside metabolic process GO:0009116 127 0.010
alpha amino acid metabolic process GO:1901605 20 0.010
Fly
synapse organization GO:0050808 196 0.010
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
molting cycle GO:0042303 56 0.010
exocrine system development GO:0035272 162 0.010
multi organism reproductive behavior GO:0044705 121 0.010
immune response activating signal transduction GO:0002757 2 0.010
mrna processing GO:0006397 104 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
lipid metabolic process GO:0006629 121 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
embryonic axis specification GO:0000578 107 0.010
atp metabolic process GO:0046034 49 0.010
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
immune response regulating signaling pathway GO:0002764 2 0.010

b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
disease of anatomical entity DOID:7 0 0.031
inherited metabolic disorder DOID:655 0 0.025
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.012
integumentary system disease DOID:16 0 0.012
lipid metabolism disorder DOID:3146 0 0.011
familial hypertriglyceridemia DOID:0050527 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.010
glucose metabolism disease DOID:4194 0 0.010
acquired metabolic disease DOID:0060158 0 0.010