Drosophila melanogaster

96 known processes

HLHmdelta (Dmel_CG8328)

E(spl) region transcript mdelta

(Aliases: E(spl)-mdelta,E(spl)delta,mdelta,mdelta0.5,E(spl)mdelta,mC,CG8328,E(Spl) HLH-m delta,E(Spl)-HLH-mdelta,bHLHc14,HLHMD,E(spl)mC,HLH-mdelta,E(spl)Mdelta,E(spl) mdelta,Dmel\CG8328,HLHmC)

HLHmdelta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ precursor cell fate determination GO:0016360 19 1.000
Fly
cell fate determination involved in pattern specification GO:0060582 19 1.000
Fly
r7 cell differentiation GO:0045466 43 1.000
neuron fate determination GO:0048664 1 1.000
Mouse
formation of organ boundary GO:0010160 30 1.000
Fly
r1 r6 cell differentiation GO:0048052 4 0.999
sensory organ boundary specification GO:0008052 22 0.999
Fly
formation of anatomical boundary GO:0048859 37 0.999
Fly
cell fate determination GO:0001709 91 0.999
Mouse Fly
organ formation GO:0048645 39 0.993
Fly
tyrosine phosphorylation of stat protein GO:0007260 1 0.985
Mouse
glial cell fate commitment GO:0021781 3 0.984
Mouse
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.983
Rat
positive regulation of bmp signaling pathway GO:0030513 5 0.981
Mouse
sex determination establishment of x a ratio GO:0007540 1 0.975
Fly
cell fate commitment involved in pattern specification GO:0060581 31 0.969
Fly
compound eye photoreceptor cell differentiation GO:0001751 140 0.966
respiratory system development GO:0060541 213 0.950
Fly
nephron tubule morphogenesis GO:0072078 3 0.949
Mouse
nephron morphogenesis GO:0072028 3 0.949
Mouse
regulation of glial cell differentiation GO:0045685 1 0.946
Mouse
epithelial tube formation GO:0072175 7 0.943
Mouse
notch signaling pathway GO:0007219 120 0.940
Human Zebrafish Mouse Fly
regulation of neuroblast proliferation GO:1902692 34 0.937
Fly
somatic sex determination GO:0018993 2 0.930
Fly
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.930
Mouse
open tracheal system development GO:0007424 204 0.928
Fly
nephron tubule development GO:0072080 3 0.924
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.916
eye development GO:0001654 323 0.907
primary sex determination soma GO:0007539 2 0.907
Fly
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.905
Zebrafish
regulation of timing of cell differentiation GO:0048505 1 0.900
Mouse
nephron epithelium morphogenesis GO:0072088 3 0.899
Mouse
regulation of notch signaling pathway GO:0008593 100 0.889
Mouse
regulation of stem cell proliferation GO:0072091 40 0.885
Fly
stem cell maintenance GO:0019827 67 0.879
Human Mouse Rat
dosage compensation GO:0007549 16 0.871
Fly
negative regulation of gene expression GO:0010629 387 0.865
embryonic epithelial tube formation GO:0001838 6 0.862
Mouse
camera type eye development GO:0043010 4 0.858
Mouse
peripheral nervous system development GO:0007422 52 0.850
Zebrafish
negative regulation of stem cell differentiation GO:2000737 8 0.847
Human
eye photoreceptor cell differentiation GO:0001754 145 0.847
startle response GO:0001964 16 0.842
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.842
nephron tubule formation GO:0072079 3 0.840
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.837
nerve development GO:0021675 6 0.836
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.832
compound eye development GO:0048749 307 0.824
tube development GO:0035295 244 0.822
Zebrafish Mouse Fly
kidney epithelium development GO:0072073 3 0.816
Mouse
embryonic morphogenesis GO:0048598 206 0.814
Zebrafish Mouse
cell fate specification GO:0001708 71 0.813
Worm
compound eye morphogenesis GO:0001745 249 0.811
regulation of neural precursor cell proliferation GO:2000177 35 0.804
Fly
neural precursor cell proliferation GO:0061351 75 0.803
Fly
neuronal stem cell maintenance GO:0097150 4 0.795
Human Mouse Rat
cranial nerve development GO:0021545 1 0.792
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.786
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.778
glial cell differentiation GO:0010001 35 0.748
Mouse Rat
regulation of gene expression epigenetic GO:0040029 128 0.746
Fly
renal tubule morphogenesis GO:0061333 44 0.743
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.742
kidney development GO:0001822 3 0.742
Mouse
tube morphogenesis GO:0035239 191 0.739
Mouse Fly
gliogenesis GO:0042063 80 0.733
Zebrafish Mouse Rat
nephron epithelium development GO:0072009 3 0.722
Mouse
rhythmic process GO:0048511 106 0.713
Mouse
kidney morphogenesis GO:0060993 3 0.708
Mouse
negative regulation of cell development GO:0010721 62 0.705
Zebrafish Mouse Rat
regulation of stem cell differentiation GO:2000736 14 0.705
Human
nephron development GO:0072006 3 0.705
Mouse
larval behavior GO:0030537 42 0.693
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.689
tube formation GO:0035148 21 0.685
Mouse
photoreceptor cell differentiation GO:0046530 170 0.685
positive regulation of cellular amine metabolic process GO:0033240 0 0.683
negative regulation of transcription dna templated GO:0045892 237 0.679
axon development GO:0061564 297 0.679
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.679
cellular amino acid metabolic process GO:0006520 61 0.675
positive regulation of transcription dna templated GO:0045893 266 0.657
Mouse
central nervous system development GO:0007417 201 0.652
Zebrafish Mouse Rat Fly
eye morphogenesis GO:0048592 260 0.652
bmp signaling pathway GO:0030509 27 0.648
Mouse
gland morphogenesis GO:0022612 145 0.647
Fly
single organism behavior GO:0044708 391 0.639
Fly
adult behavior GO:0030534 137 0.625
Fly
axon ensheathment in central nervous system GO:0032291 3 0.622
Mouse
gland development GO:0048732 191 0.622
Fly
axonogenesis GO:0007409 290 0.620
Zebrafish
regulation of mitosis GO:0007088 56 0.603
Fly
hair cell differentiation GO:0035315 47 0.601
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.599
Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.590
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.589
peptidyl tyrosine phosphorylation GO:0018108 24 0.579
Mouse
axon ensheathment GO:0008366 10 0.577
Mouse
glial cell development GO:0021782 27 0.552
Mouse
neuron fate commitment GO:0048663 50 0.547
Mouse
ensheathment of neurons GO:0007272 10 0.542
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.539
Mouse
salivary gland development GO:0007431 162 0.533
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.521
peripheral nervous system neuron differentiation GO:0048934 8 0.513
Zebrafish
salivary gland morphogenesis GO:0007435 145 0.507
Fly
cellular ketone metabolic process GO:0042180 24 0.507
head development GO:0060322 135 0.506
Zebrafish Mouse Rat Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.502
Mouse
renal system development GO:0072001 72 0.502
Mouse
regulation of neuron differentiation GO:0045664 103 0.495
Mouse Rat
epidermal cell differentiation GO:0009913 51 0.495
Mouse Worm
response to abiotic stimulus GO:0009628 341 0.493
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.491
Mouse
segment specification GO:0007379 33 0.475
Zebrafish Mouse
peptidyl tyrosine modification GO:0018212 24 0.470
Mouse
morphogenesis of an epithelium GO:0002009 276 0.467
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.467
cell maturation GO:0048469 144 0.464
Mouse
sex determination GO:0007530 18 0.464
Fly
exocrine system development GO:0035272 162 0.463
Fly
brain morphogenesis GO:0048854 16 0.456
Fly
epidermis development GO:0008544 65 0.450
Mouse Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.447
regulation of nervous system development GO:0051960 248 0.445
Zebrafish Mouse Rat Fly
renal tubule development GO:0061326 64 0.439
Mouse
neuronal action potential GO:0019228 10 0.429
Mouse
brain development GO:0007420 120 0.429
Zebrafish Mouse Rat Fly
smoothened signaling pathway GO:0007224 49 0.428
Mouse
peripheral nervous system neuron development GO:0048935 8 0.426
Zebrafish
regulation of neurogenesis GO:0050767 158 0.421
Zebrafish Mouse Rat Fly
locomotory behavior GO:0007626 176 0.420
Fly
larval locomotory behavior GO:0008345 27 0.420
Fly
urogenital system development GO:0001655 72 0.418
Mouse
cellular protein modification process GO:0006464 438 0.414
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.413
Mouse
mesoderm development GO:0007498 78 0.409
Fly
regulation of bmp signaling pathway GO:0030510 23 0.407
Mouse
positive regulation of stem cell proliferation GO:2000648 8 0.407
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.407
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.405
organic acid metabolic process GO:0006082 103 0.405
negative regulation of gliogenesis GO:0014014 6 0.397
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.392
regulation of cell development GO:0060284 215 0.390
Zebrafish Mouse Rat Fly
cellular response to dna damage stimulus GO:0006974 223 0.385
Fly
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.385
Mouse
neuroblast proliferation GO:0007405 74 0.384
Fly
jak stat cascade GO:0007259 49 0.380
Mouse
positive regulation of cell proliferation GO:0008284 47 0.379
Human Fly
oxoacid metabolic process GO:0043436 103 0.377
sensory organ morphogenesis GO:0090596 260 0.373
enzyme linked receptor protein signaling pathway GO:0007167 179 0.366
Mouse
immune system process GO:0002376 347 0.364
Rat
stem cell differentiation GO:0048863 117 0.361
Human Mouse Rat
hematopoietic progenitor cell differentiation GO:0002244 1 0.359
Rat
neurological system process GO:0050877 358 0.355
Mouse Fly
epithelial tube morphogenesis GO:0060562 88 0.354
Mouse
tissue morphogenesis GO:0048729 297 0.352
Mouse
positive regulation of neuroblast proliferation GO:0002052 7 0.350
Fly
amine metabolic process GO:0009308 12 0.334
regulation of cell differentiation GO:0045595 302 0.329
Human Zebrafish Mouse Rat Fly
regulation of phosphate metabolic process GO:0019220 210 0.327
Zebrafish Mouse
regulation of protein metabolic process GO:0051246 256 0.325
Zebrafish Mouse
protein complex biogenesis GO:0070271 201 0.318
Mouse
regulation of nuclear division GO:0051783 58 0.318
Fly
developmental maturation GO:0021700 172 0.316
Mouse
cell proliferation GO:0008283 299 0.310
Human Fly
hindbrain development GO:0030902 2 0.309
Mouse
positive regulation of gene expression GO:0010628 290 0.307
Mouse
protein complex assembly GO:0006461 200 0.305
Mouse
negative regulation of immune system process GO:0002683 50 0.305
Rat
skin development GO:0043588 65 0.302
Mouse Worm
regulation of intracellular signal transduction GO:1902531 236 0.302
Mouse
regulation of cell proliferation GO:0042127 163 0.300
Human Fly
positive regulation of mitotic cell cycle GO:0045931 34 0.298
Fly
connective tissue development GO:0061448 3 0.292
Human Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.286
Mouse
proximal distal pattern formation GO:0009954 15 0.283
Mouse
regulation of catalytic activity GO:0050790 185 0.282
Zebrafish
telencephalon development GO:0021537 2 0.274
Mouse
regulation of multicellular organismal development GO:2000026 414 0.273
Zebrafish Mouse Rat Fly
imaginal disc pattern formation GO:0007447 91 0.273
Fly
regulation of response to stress GO:0080134 200 0.269
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.265
Mouse
small molecule metabolic process GO:0044281 305 0.265
embryonic hindgut morphogenesis GO:0048619 48 0.265
positive regulation of neurogenesis GO:0050769 41 0.256
Fly
positive regulation of cell development GO:0010720 61 0.255
Fly
regulation of cell cycle process GO:0010564 181 0.250
Fly
developmental cell growth GO:0048588 52 0.249
positive regulation of organelle organization GO:0010638 65 0.247
Fly
positive regulation of cell differentiation GO:0045597 64 0.246
Fly
wing disc pattern formation GO:0035222 66 0.246
Fly
mitotic nuclear division GO:0007067 213 0.242
Fly
protein modification process GO:0036211 438 0.240
Zebrafish Mouse
positive regulation of catalytic activity GO:0043085 118 0.238
Zebrafish
regulation of protein kinase activity GO:0045859 51 0.236
Zebrafish
carboxylic acid metabolic process GO:0019752 92 0.236
dendrite development GO:0016358 204 0.231
Fly
organonitrogen compound metabolic process GO:1901564 318 0.230
stem cell proliferation GO:0072089 88 0.229
Fly
organelle fission GO:0048285 340 0.226
Fly
endoderm development GO:0007492 6 0.226
Zebrafish
cellular amine metabolic process GO:0044106 12 0.221
positive regulation of cellular component organization GO:0051130 156 0.219
Fly
dendrite morphogenesis GO:0048813 199 0.219
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.217
Zebrafish
positive regulation of protein metabolic process GO:0051247 128 0.215
Zebrafish Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.213
Zebrafish Mouse
regulation of membrane potential GO:0042391 35 0.212
Mouse
response to decreased oxygen levels GO:0036293 58 0.209
Fly
neuron fate specification GO:0048665 12 0.208
regulation of cellular response to stress GO:0080135 89 0.204
Fly
neuroblast fate specification GO:0014018 2 0.203
protein phosphorylation GO:0006468 169 0.203
Zebrafish Mouse
stem cell fate specification GO:0048866 2 0.200
regulation of organelle organization GO:0033043 196 0.198
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.198
negative regulation of cell differentiation GO:0045596 143 0.198
Human Zebrafish Mouse Rat
regulation of phosphorus metabolic process GO:0051174 210 0.197
Zebrafish Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.196
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.194
Zebrafish Mouse
regulation of cell morphogenesis GO:0022604 163 0.192
regulation of cellular ketone metabolic process GO:0010565 3 0.191
negative regulation of neurogenesis GO:0050768 53 0.190
Zebrafish Mouse Rat
positive regulation of biosynthetic process GO:0009891 316 0.188
Mouse
regulation of protein serine threonine kinase activity GO:0071900 25 0.187
Zebrafish
positive regulation of cellular protein metabolic process GO:0032270 118 0.187
Zebrafish Mouse
stem cell fate commitment GO:0048865 25 0.185
anterior posterior pattern specification GO:0009952 136 0.183
Zebrafish Mouse Worm
positive regulation of cell cycle process GO:0090068 28 0.183
Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.182
adult locomotory behavior GO:0008344 76 0.180
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.179
Mouse
positive regulation of developmental process GO:0051094 143 0.178
Fly
response to oxygen containing compound GO:1901700 200 0.177
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.175
nuclear division GO:0000280 332 0.175
Fly
regulation of transferase activity GO:0051338 58 0.171
Zebrafish
regulation of cellular protein metabolic process GO:0032268 243 0.169
Zebrafish Mouse
compound eye photoreceptor fate commitment GO:0001752 36 0.169
positive regulation of rna metabolic process GO:0051254 271 0.168
Mouse
negative regulation of developmental process GO:0051093 201 0.167
Human Zebrafish Mouse Rat
transmission of nerve impulse GO:0019226 12 0.164
Mouse
intracellular signal transduction GO:0035556 300 0.162
Mouse
regulation of response to dna damage stimulus GO:2001020 23 0.162
Fly
positive regulation of neural precursor cell proliferation GO:2000179 8 0.160
Fly
lateral inhibition GO:0046331 206 0.160
regulation of gliogenesis GO:0014013 11 0.159
Mouse
fat soluble vitamin biosynthetic process GO:0042362 1 0.157
cell division GO:0051301 248 0.156
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.152
Fly
regulation of cell cycle GO:0051726 291 0.152
Zebrafish Fly
dorsal ventral pattern formation GO:0009953 133 0.151
Fly
positive regulation of notch signaling pathway GO:0045747 34 0.150
Mouse
positive regulation of cell communication GO:0010647 250 0.148
Mouse
embryonic organ morphogenesis GO:0048562 5 0.148
Zebrafish
digestive tract morphogenesis GO:0048546 127 0.147
neuromuscular process GO:0050905 21 0.144
Fly
regulation of immune system process GO:0002682 176 0.137
Rat
regulation of kinase activity GO:0043549 53 0.136
Zebrafish
positive regulation of protein phosphorylation GO:0001934 34 0.135
Zebrafish Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.133
peptidyl amino acid modification GO:0018193 105 0.133
Mouse
positive regulation of nervous system development GO:0051962 69 0.132
Fly
malpighian tubule morphogenesis GO:0007443 44 0.131
cellular response to abiotic stimulus GO:0071214 58 0.131
regionalization GO:0003002 416 0.131
Zebrafish Mouse Worm Fly
response to hypoxia GO:0001666 53 0.129
Fly
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.129
forebrain development GO:0030900 2 0.129
Mouse Rat
regulation of molecular function GO:0065009 217 0.128
Zebrafish
segmentation GO:0035282 207 0.127
Zebrafish Mouse
positive regulation of cell cycle GO:0045787 43 0.126
Zebrafish Fly
response to other organism GO:0051707 293 0.125
chaeta development GO:0022416 97 0.122
hemopoiesis GO:0030097 46 0.122
Rat
stem cell development GO:0048864 79 0.122
Human Mouse Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.121
humoral immune response GO:0006959 117 0.120
biological adhesion GO:0022610 138 0.120
Mouse
regulation of neuron projection development GO:0010975 69 0.111
regulation of protein modification process GO:0031399 112 0.110
Zebrafish Mouse
neuron projection guidance GO:0097485 241 0.109
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.109
Fly
regulation of phosphorylation GO:0042325 147 0.108
Zebrafish Mouse
positive regulation of molecular function GO:0044093 136 0.107
Zebrafish
phosphorylation GO:0016310 294 0.106
Zebrafish Mouse
wing disc dorsal ventral pattern formation GO:0048190 47 0.106
Fly
neuroepithelial cell differentiation GO:0060563 6 0.104
regulation of protein phosphorylation GO:0001932 64 0.104
Zebrafish Mouse
negative regulation of nervous system development GO:0051961 92 0.104
Zebrafish Mouse Rat
positive regulation of protein modification process GO:0031401 58 0.103
Zebrafish Mouse
epithelial cell differentiation GO:0030855 322 0.101
Mouse Worm
positive regulation of signal transduction GO:0009967 223 0.100
Mouse
positive regulation of protein kinase activity GO:0045860 25 0.098
Zebrafish
hindgut morphogenesis GO:0007442 58 0.097
regulation of mitotic cell cycle GO:0007346 190 0.097
Fly
hematopoietic or lymphoid organ development GO:0048534 57 0.096
Rat
regulation of cell division GO:0051302 72 0.096
Fly
bolwig s organ development GO:0055034 8 0.095
macromolecular complex assembly GO:0065003 256 0.093
Mouse
positive regulation of phosphorylation GO:0042327 87 0.089
Zebrafish Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.086
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.084
Zebrafish Mouse Rat
positive regulation of response to stimulus GO:0048584 323 0.082
Mouse
action potential GO:0001508 13 0.077
Mouse
negative regulation of notch signaling pathway GO:0045746 41 0.075
spinal cord patterning GO:0021511 1 0.074
response to external biotic stimulus GO:0043207 293 0.074
regulation of axonogenesis GO:0050770 32 0.074
medulla oblongata development GO:0021550 2 0.072
cell migration GO:0016477 238 0.070
immune system development GO:0002520 57 0.069
Rat
single organism biosynthetic process GO:0044711 206 0.067
cell adhesion GO:0007155 136 0.064
Mouse
multicellular organismal signaling GO:0035637 12 0.062
Mouse
muscle organ development GO:0007517 127 0.061
positive regulation of signaling GO:0023056 243 0.061
Mouse
neuron projection extension GO:1990138 32 0.059
negative regulation of cell communication GO:0010648 223 0.059
regulation of anatomical structure size GO:0090066 163 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.057
positive regulation of intracellular signal transduction GO:1902533 116 0.057
Mouse
positive regulation of kinase activity GO:0033674 25 0.057
Zebrafish
glial cell proliferation GO:0014009 13 0.056
response to organic substance GO:0010033 284 0.055
camera type eye morphogenesis GO:0048593 2 0.054
response to oxygen levels GO:0070482 59 0.054
Fly
localization of cell GO:0051674 257 0.051
digestive tract development GO:0048565 149 0.050
compound eye cone cell differentiation GO:0042675 13 0.050
catabolic process GO:0009056 409 0.049
axon extension involved in axon guidance GO:0048846 10 0.047
regulation of cell death GO:0010941 173 0.046
compound eye cone cell fate commitment GO:0042676 5 0.046
regulation of glial cell proliferation GO:0060251 11 0.044
cellular catabolic process GO:0044248 372 0.044
bolwig s organ morphogenesis GO:0001746 8 0.041
negative regulation of cell cycle process GO:0010948 109 0.041
positive regulation of transferase activity GO:0051347 26 0.040
Zebrafish
retina morphogenesis in camera type eye GO:0060042 2 0.040
regulation of axon extension GO:0030516 8 0.040
negative regulation of glial cell proliferation GO:0060253 6 0.040
developmental pigmentation GO:0048066 68 0.039
germarium derived egg chamber formation GO:0007293 101 0.039
positive regulation of phosphorus metabolic process GO:0010562 139 0.039
Zebrafish Mouse
chaeta morphogenesis GO:0008407 42 0.039
regulation of cellular component size GO:0032535 98 0.038
stem cell fate determination GO:0048867 15 0.038
positive regulation of cell division GO:0051781 16 0.038
Fly
photoreceptor cell fate commitment GO:0046552 41 0.038
gastrulation with mouth forming first GO:0001703 36 0.037
wing disc morphogenesis GO:0007472 344 0.037
programmed cell death GO:0012501 257 0.037
pigmentation GO:0043473 75 0.036
regulation of axon guidance GO:1902667 10 0.036
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
sensory perception GO:0007600 196 0.034
defense response to other organism GO:0098542 225 0.033
cell death GO:0008219 279 0.033
digestive system development GO:0055123 149 0.031
death GO:0016265 284 0.031
developmental programmed cell death GO:0010623 138 0.030
appendage development GO:0048736 401 0.029
glandular epithelial cell differentiation GO:0002067 1 0.029
regulation of cellular amide metabolic process GO:0034248 39 0.029
positive regulation of neuron differentiation GO:0045666 26 0.029
gastrulation involving germ band extension GO:0010004 36 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
response to bacterium GO:0009617 198 0.028
retina development in camera type eye GO:0060041 4 0.027
regulation of axon extension involved in axon guidance GO:0048841 4 0.027
spinal cord dorsal ventral patterning GO:0021513 1 0.027
regulation of jak stat cascade GO:0046425 43 0.027
Mouse
epithelial cell migration GO:0010631 148 0.027
regulation of epithelial cell differentiation GO:0030856 4 0.027
negative regulation of cell cycle GO:0045786 116 0.027
eye pigmentation GO:0048069 43 0.027
negative regulation of neuron differentiation GO:0045665 16 0.026
Mouse Rat
vitamin biosynthetic process GO:0009110 1 0.026
neuroblast fate commitment GO:0014017 19 0.026
spinal cord development GO:0021510 1 0.025
embryonic organ development GO:0048568 50 0.025
Zebrafish
response to endogenous stimulus GO:0009719 119 0.024
cellular response to chemical stimulus GO:0070887 199 0.023
circadian rhythm GO:0007623 105 0.023
regulation of cell projection organization GO:0031344 92 0.022
locomotor rhythm GO:0045475 56 0.022
germ line stem cell maintenance GO:0030718 50 0.022
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.022
salivary gland cell autophagic cell death GO:0035071 83 0.021
regulation of localization GO:0032879 275 0.020
r8 cell fate commitment GO:0007460 6 0.020
muscle cell development GO:0055001 50 0.020
actin filament organization GO:0007015 126 0.020
cell growth GO:0016049 108 0.020
ommatidial rotation GO:0016318 20 0.020
regulation of compound eye cone cell fate specification GO:0042682 4 0.020
histolysis GO:0007559 102 0.019
intracellular transport GO:0046907 228 0.019
regulation of multi organism process GO:0043900 131 0.019
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.019
r7 cell fate commitment GO:0007465 12 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
axon extension GO:0048675 32 0.019
establishment of ommatidial planar polarity GO:0042067 49 0.018
hormone metabolic process GO:0042445 33 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
axon guidance GO:0007411 233 0.018
multi organism behavior GO:0051705 175 0.018
rhythmic behavior GO:0007622 76 0.018
intracellular protein transport GO:0006886 104 0.018
defense response to bacterium GO:0042742 178 0.017
antimicrobial humoral response GO:0019730 99 0.017
response to biotic stimulus GO:0009607 294 0.017
apoptotic process GO:0006915 159 0.017
regulation of immune effector process GO:0002697 52 0.016
oenocyte development GO:0007438 8 0.016
gene silencing GO:0016458 138 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
eye antennal disc morphogenesis GO:0007455 34 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.015
vitamin metabolic process GO:0006766 2 0.015
epithelial cell development GO:0002064 274 0.015
autophagic cell death GO:0048102 83 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
actin cytoskeleton organization GO:0030036 206 0.015
regulation of gene silencing GO:0060968 63 0.015
negative regulation of signal transduction GO:0009968 206 0.015
antimicrobial peptide production GO:0002775 46 0.015
salivary gland histolysis GO:0035070 88 0.015
defense response GO:0006952 300 0.015
apoptotic process involved in morphogenesis GO:0060561 3 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
central nervous system neuron differentiation GO:0021953 8 0.014
Rat
lipid metabolic process GO:0006629 121 0.014
somatic stem cell maintenance GO:0035019 14 0.014
camera type eye photoreceptor cell differentiation GO:0060219 2 0.014
tissue death GO:0016271 102 0.014
negative regulation of signaling GO:0023057 219 0.014
gene silencing by rna GO:0031047 57 0.014
cellular lipid metabolic process GO:0044255 83 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
central nervous system neuron development GO:0021954 8 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
appendage morphogenesis GO:0035107 397 0.013
regulation of hemocyte proliferation GO:0035206 37 0.013
single organism cellular localization GO:1902580 180 0.013
peptide biosynthetic process GO:0043043 42 0.013
retinal cone cell differentiation GO:0042670 2 0.013
regulation of developmental growth GO:0048638 174 0.013
body morphogenesis GO:0010171 2 0.013
regulation of response to external stimulus GO:0032101 115 0.013
response to hexose GO:0009746 3 0.013
organic substance transport GO:0071702 257 0.012
positive regulation of jak stat cascade GO:0046427 24 0.012
Mouse
cellular response to organic substance GO:0071310 132 0.012
macromolecule catabolic process GO:0009057 161 0.012
gastrulation GO:0007369 70 0.011
regulation of programmed cell death GO:0043067 152 0.011
protein localization to organelle GO:0033365 82 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
neural retina development GO:0003407 4 0.011
regulation of epidermal cell differentiation GO:0045604 3 0.011
phagocytosis GO:0006909 215 0.011
r3 r4 cell differentiation GO:0048056 12 0.010
leg disc development GO:0035218 92 0.010
response to alcohol GO:0097305 95 0.010
developmental growth GO:0048589 280 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
protein processing GO:0016485 68 0.010

HLHmdelta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.935
Human
bone disease DOID:0080001 0 0.935
Human
disease of anatomical entity DOID:7 0 0.935
Human
dysostosis DOID:1934 0 0.935
Human
musculoskeletal system disease DOID:17 0 0.935
Human
connective tissue disease DOID:65 0 0.935
Human
spondylocostal dysostosis DOID:0050568 0 0.707
Human
cardiovascular system disease DOID:1287 0 0.014