Drosophila melanogaster

15 known processes

l(2)k14710 (Dmel_CG8325)

lethal (2) k14710

(Aliases: BcDNA:LD21719,CG8325,Dmel\CG8325,l(2)k15603)

l(2)k14710 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of small gtpase mediated signal transduction GO:0051056 93 0.235
ras protein signal transduction GO:0007265 88 0.208
protein catabolic process GO:0030163 101 0.197
positive regulation of protein catabolic process GO:0045732 34 0.146
cell proliferation GO:0008283 299 0.144
cellular macromolecule catabolic process GO:0044265 136 0.136
organic substance catabolic process GO:1901575 308 0.125
positive regulation of macromolecule metabolic process GO:0010604 405 0.121
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.120
positive regulation of phosphate metabolic process GO:0045937 139 0.119
prenylation GO:0097354 3 0.104
catabolic process GO:0009056 409 0.104
proteolysis GO:0006508 192 0.097
intracellular signal transduction GO:0035556 300 0.092
regulation of intracellular signal transduction GO:1902531 236 0.085
purine ribonucleotide catabolic process GO:0009154 109 0.083
protein modification process GO:0036211 438 0.082
regulation of catalytic activity GO:0050790 185 0.081
positive regulation of phosphorus metabolic process GO:0010562 139 0.080
regulation of phosphorus metabolic process GO:0051174 210 0.069
regulation of molecular function GO:0065009 217 0.067
small gtpase mediated signal transduction GO:0007264 88 0.066
biological adhesion GO:0022610 138 0.062
protein prenylation GO:0018342 3 0.058
cellular macromolecular complex assembly GO:0034622 153 0.057
phosphorylation GO:0016310 294 0.057
developmental growth GO:0048589 280 0.056
macromolecule catabolic process GO:0009057 161 0.054
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.054
regulation of phosphate metabolic process GO:0019220 210 0.053
organonitrogen compound metabolic process GO:1901564 318 0.051
positive regulation of cellular biosynthetic process GO:0031328 316 0.051
positive regulation of response to stimulus GO:0048584 323 0.050
erk1 and erk2 cascade GO:0070371 39 0.049
positive regulation of rna metabolic process GO:0051254 271 0.049
cellular protein modification process GO:0006464 438 0.048
organophosphate metabolic process GO:0019637 195 0.047
cell adhesion GO:0007155 136 0.046
regulation of ras protein signal transduction GO:0046578 93 0.046
positive regulation of catalytic activity GO:0043085 118 0.046
positive regulation of phosphorylation GO:0042327 87 0.046
establishment of localization in cell GO:0051649 402 0.045
positive regulation of molecular function GO:0044093 136 0.045
single organism intracellular transport GO:1902582 207 0.044
positive regulation of cellular amine metabolic process GO:0033240 0 0.044
ion transport GO:0006811 145 0.044
transmembrane transport GO:0055085 139 0.043
purine ribonucleoside metabolic process GO:0046128 127 0.043
internal protein amino acid acetylation GO:0006475 38 0.042
response to organic substance GO:0010033 284 0.042
cellular catabolic process GO:0044248 372 0.041
mapk cascade GO:0000165 107 0.041
regulation of proteolysis GO:0030162 87 0.041
purine nucleoside metabolic process GO:0042278 127 0.041
positive regulation of gene expression GO:0010628 290 0.040
purine ribonucleotide metabolic process GO:0009150 145 0.039
regulation of hydrolase activity GO:0051336 97 0.039
intracellular transport GO:0046907 228 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
cellular protein catabolic process GO:0044257 83 0.036
positive regulation of catabolic process GO:0009896 105 0.036
cellular ion homeostasis GO:0006873 39 0.035
cell division GO:0051301 248 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
plasma membrane organization GO:0007009 26 0.034
macromolecular complex assembly GO:0065003 256 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.033
positive regulation of signaling GO:0023056 243 0.032
purine containing compound metabolic process GO:0072521 155 0.031
positive regulation of biosynthetic process GO:0009891 316 0.031
small molecule metabolic process GO:0044281 305 0.031
protein complex assembly GO:0006461 200 0.030
cellular homeostasis GO:0019725 80 0.029
vesicle mediated transport GO:0016192 381 0.028
regulation of erk1 and erk2 cascade GO:0070372 39 0.028
homeostatic process GO:0042592 199 0.028
positive regulation of hydrolase activity GO:0051345 78 0.028
hindbrain development GO:0030902 2 0.027
regulation of phosphorylation GO:0042325 147 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
positive regulation of mapk cascade GO:0043410 63 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
modification dependent protein catabolic process GO:0019941 78 0.025
single organism catabolic process GO:0044712 228 0.025
positive regulation of ras gtpase activity GO:0032320 36 0.025
protein geranylgeranylation GO:0018344 3 0.025
regulation of protein modification process GO:0031399 112 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
organic substance transport GO:0071702 257 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.023
ribonucleoside triphosphate metabolic process GO:0009199 119 0.023
cellular chemical homeostasis GO:0055082 40 0.023
ion transmembrane transport GO:0034220 122 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.023
immune system process GO:0002376 347 0.022
lipid localization GO:0010876 54 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
immune system development GO:0002520 57 0.021
regulation of neurogenesis GO:0050767 158 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
single organism cellular localization GO:1902580 180 0.021
purine containing compound catabolic process GO:0072523 112 0.021
amine metabolic process GO:0009308 12 0.021
macromolecular complex disassembly GO:0032984 37 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.020
regulation of cell division GO:0051302 72 0.020
immune response GO:0006955 246 0.020
purine nucleotide catabolic process GO:0006195 109 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.019
ion homeostasis GO:0050801 55 0.019
regulation of gtp catabolic process GO:0033124 44 0.019
protein acylation GO:0043543 42 0.019
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
positive regulation of nucleoside metabolic process GO:0045979 47 0.019
regulation of cellular catabolic process GO:0031329 157 0.018
glycosyl compound catabolic process GO:1901658 112 0.018
regulation of cell proliferation GO:0042127 163 0.018
adherens junction organization GO:0034332 27 0.018
signal transduction by phosphorylation GO:0023014 107 0.018
endomembrane system organization GO:0010256 119 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
regulation of cell cycle GO:0051726 291 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
regulation of meiosis GO:0040020 3 0.018
protein dna complex subunit organization GO:0071824 86 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.017
protein ubiquitination GO:0016567 70 0.017
regulation of growth GO:0040008 233 0.017
positive regulation of nucleotide catabolic process GO:0030813 46 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
organonitrogen compound catabolic process GO:1901565 128 0.016
aromatic compound catabolic process GO:0019439 166 0.016
negative regulation of cell cycle GO:0045786 116 0.016
organelle assembly GO:0070925 198 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
regulation of neuron differentiation GO:0045664 103 0.016
developmental maturation GO:0021700 172 0.016
body morphogenesis GO:0010171 2 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
protein phosphorylation GO:0006468 169 0.016
regulation of mapk cascade GO:0043408 92 0.016
positive regulation of signal transduction GO:0009967 223 0.016
regulation of epithelial cell proliferation GO:0050678 4 0.016
positive regulation of intracellular transport GO:0032388 42 0.016
regulation of cellular component size GO:0032535 98 0.016
heterocycle catabolic process GO:0046700 166 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
nucleoside metabolic process GO:0009116 127 0.015
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.015
regulation of localization GO:0032879 275 0.015
axonogenesis GO:0007409 290 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
detection of stimulus GO:0051606 156 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
peptidyl amino acid modification GO:0018193 105 0.015
meiotic nuclear division GO:0007126 151 0.015
regulation of purine nucleotide catabolic process GO:0033121 48 0.015
regulation of cell shape GO:0008360 113 0.015
retina development in camera type eye GO:0060041 4 0.015
forebrain development GO:0030900 2 0.015
regulation of ion transport GO:0043269 39 0.015
positive regulation of transport GO:0051050 92 0.015
wing disc morphogenesis GO:0007472 344 0.015
nephron development GO:0072006 3 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of cell development GO:0060284 215 0.014
regulation of protein ubiquitination GO:0031396 22 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
defense response to bacterium GO:0042742 178 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.014
intracellular protein transmembrane transport GO:0065002 4 0.014
spindle organization GO:0007051 253 0.014
nucleotide metabolic process GO:0009117 161 0.014
ribonucleoside metabolic process GO:0009119 127 0.013
nucleotide catabolic process GO:0009166 109 0.013
reactive oxygen species metabolic process GO:0072593 22 0.013
phagocytosis GO:0006909 215 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
axon development GO:0061564 297 0.013
monocarboxylic acid transport GO:0015718 3 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.013
telencephalon development GO:0021537 2 0.013
dna templated transcription elongation GO:0006354 18 0.013
regulation of transferase activity GO:0051338 58 0.013
positive regulation of ras protein signal transduction GO:0046579 43 0.013
regulation of transport GO:0051049 181 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
growth GO:0040007 359 0.012
meiotic cell cycle GO:0051321 171 0.012
disaccharide metabolic process GO:0005984 4 0.012
regulation of ras gtpase activity GO:0032318 38 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
endocytosis GO:0006897 310 0.012
neuron projection guidance GO:0097485 241 0.012
cellular component disassembly GO:0022411 46 0.012
organic acid metabolic process GO:0006082 103 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
positive regulation of cell communication GO:0010647 250 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
histone acetylation GO:0016573 38 0.011
oxoacid metabolic process GO:0043436 103 0.011
inositol lipid mediated signaling GO:0048017 4 0.011
regulation of protein catabolic process GO:0042176 55 0.011
regulation of nervous system development GO:0051960 248 0.011
positive regulation of gtp catabolic process GO:0033126 43 0.011
cell aging GO:0007569 2 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
positive regulation of organelle organization GO:0010638 65 0.011
death GO:0016265 284 0.011
protein kinase b signaling GO:0043491 1 0.011
regulation of neuron projection development GO:0010975 69 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
cell migration GO:0016477 238 0.010
single organism biosynthetic process GO:0044711 206 0.010
cellular cation homeostasis GO:0030003 38 0.010
programmed cell death GO:0012501 257 0.010
positive regulation of nucleotide metabolic process GO:0045981 55 0.010
regulation of protein kinase activity GO:0045859 51 0.010

l(2)k14710 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.036
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034