Drosophila melanogaster

0 known processes

SpdS (Dmel_CG8327)

Spermidine Synthase

(Aliases: Dmel\CG8327,CG8327)

SpdS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.086
small molecule metabolic process GO:0044281 305 0.084
defense response GO:0006952 300 0.060
homeostatic process GO:0042592 199 0.057
response to external biotic stimulus GO:0043207 293 0.048
regulation of cell death GO:0010941 173 0.047
positive regulation of response to stimulus GO:0048584 323 0.046
regulation of neuron death GO:1901214 26 0.045
death GO:0016265 284 0.045
response to biotic stimulus GO:0009607 294 0.045
response to oxidative stress GO:0006979 86 0.043
single organism biosynthetic process GO:0044711 206 0.043
response to other organism GO:0051707 293 0.043
nucleoside phosphate metabolic process GO:0006753 162 0.042
defense response to bacterium GO:0042742 178 0.041
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
Rat
developmental programmed cell death GO:0010623 138 0.040
apoptotic process GO:0006915 159 0.039
regulation of response to stress GO:0080134 200 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.038
single organism behavior GO:0044708 391 0.036
response to abiotic stimulus GO:0009628 341 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
cell death GO:0008219 279 0.033
carboxylic acid metabolic process GO:0019752 92 0.032
anatomical structure homeostasis GO:0060249 97 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
negative regulation of signal transduction GO:0009968 206 0.031
cellular response to oxidative stress GO:0034599 28 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.030
immune system process GO:0002376 347 0.029
appendage morphogenesis GO:0035107 397 0.029
endocytosis GO:0006897 310 0.027
single organism catabolic process GO:0044712 228 0.027
aromatic compound catabolic process GO:0019439 166 0.026
innate immune response GO:0045087 144 0.026
positive regulation of signal transduction GO:0009967 223 0.026
regulation of apoptotic process GO:0042981 130 0.026
cellular response to dna damage stimulus GO:0006974 223 0.026
regulation of immune response GO:0050776 118 0.025
aging GO:0007568 143 0.025
phagocytosis GO:0006909 215 0.025
regulation of catalytic activity GO:0050790 185 0.025
response to bacterium GO:0009617 198 0.025
catabolic process GO:0009056 409 0.024
nucleoside phosphate biosynthetic process GO:1901293 34 0.024
defense response to other organism GO:0098542 225 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.023
protein localization GO:0008104 284 0.023
gland development GO:0048732 191 0.023
regulation of protein metabolic process GO:0051246 256 0.023
regulation of programmed cell death GO:0043067 152 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
purine containing compound metabolic process GO:0072521 155 0.022
embryonic development via the syncytial blastoderm GO:0001700 148 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.021
Rat
response to nutrient levels GO:0031667 114 0.021
positive regulation of signaling GO:0023056 243 0.021
oxidation reduction process GO:0055114 123 0.021
multicellular organismal aging GO:0010259 140 0.020
ribonucleotide metabolic process GO:0009259 145 0.020
response to lipopolysaccharide GO:0032496 4 0.020
cell type specific apoptotic process GO:0097285 38 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
intracellular signal transduction GO:0035556 300 0.020
vesicle mediated transport GO:0016192 381 0.020
positive regulation of response to biotic stimulus GO:0002833 31 0.020
regulation of catabolic process GO:0009894 170 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.019
programmed cell death GO:0012501 257 0.019
negative regulation of cell death GO:0060548 81 0.019
telencephalon development GO:0021537 2 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
regulation of innate immune response GO:0045088 71 0.019
organic substance catabolic process GO:1901575 308 0.018
organophosphate metabolic process GO:0019637 195 0.018
oxoacid metabolic process GO:0043436 103 0.018
pigment metabolic process GO:0042440 84 0.018
response to extracellular stimulus GO:0009991 116 0.017
wing disc morphogenesis GO:0007472 344 0.017
response to starvation GO:0042594 97 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
protein complex biogenesis GO:0070271 201 0.017
developmental pigmentation GO:0048066 68 0.017
growth GO:0040007 359 0.017
regulation of multi organism process GO:0043900 131 0.017
cellular amide metabolic process GO:0043603 80 0.017
regulation of molecular function GO:0065009 217 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.016
neuron death GO:0070997 27 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
immune effector process GO:0002252 98 0.016
organic acid metabolic process GO:0006082 103 0.016
cellular homeostasis GO:0019725 80 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
regulation of defense response GO:0031347 102 0.016
purine containing compound biosynthetic process GO:0072522 30 0.015
protein modification process GO:0036211 438 0.015
positive regulation of molecular function GO:0044093 136 0.015
actin cytoskeleton organization GO:0030036 206 0.015
response to temperature stimulus GO:0009266 106 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
cellular response to external stimulus GO:0071496 66 0.014
response to virus GO:0009615 28 0.014
positive regulation of cell communication GO:0010647 250 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
response to decreased oxygen levels GO:0036293 58 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
cellular protein modification process GO:0006464 438 0.014
phosphorylation GO:0016310 294 0.014
negative regulation of signaling GO:0023057 219 0.014
positive regulation of apoptotic process GO:0043065 47 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
protein phosphorylation GO:0006468 169 0.013
establishment of localization in cell GO:0051649 402 0.013
cellular response to organic substance GO:0071310 132 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
mrna processing GO:0006397 104 0.013
activation of innate immune response GO:0002218 4 0.013
macromolecule methylation GO:0043414 45 0.013
cellular macromolecule localization GO:0070727 220 0.013
cell growth GO:0016049 108 0.013
nucleotide metabolic process GO:0009117 161 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
cell adhesion GO:0007155 136 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
negative regulation of cell communication GO:0010648 223 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
camera type eye development GO:0043010 4 0.013
chromatin organization GO:0006325 207 0.013
proteolysis GO:0006508 192 0.012
peptide biosynthetic process GO:0043043 42 0.012
cellular protein localization GO:0034613 160 0.012
localization of cell GO:0051674 257 0.012
cellular catabolic process GO:0044248 372 0.012
regulation of proteolysis GO:0030162 87 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
salivary gland morphogenesis GO:0007435 145 0.012
chromatin silencing GO:0006342 76 0.012
appendage development GO:0048736 401 0.012
nucleoside metabolic process GO:0009116 127 0.012
regulation of neuron apoptotic process GO:0043523 16 0.012
cellular modified amino acid metabolic process GO:0006575 45 0.012
regulation of organelle organization GO:0033043 196 0.012
cell proliferation GO:0008283 299 0.012
establishment of protein localization GO:0045184 163 0.012
muscle organ development GO:0007517 127 0.012
regulation of peptidase activity GO:0052547 39 0.012
antimicrobial humoral response GO:0019730 99 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
regulation of protein modification process GO:0031399 112 0.011
histolysis GO:0007559 102 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
negative regulation of neuron death GO:1901215 18 0.011
regulation of phosphorylation GO:0042325 147 0.011
dna metabolic process GO:0006259 227 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
protein transport GO:0015031 155 0.011
autophagy GO:0006914 108 0.011
purine nucleobase metabolic process GO:0006144 2 0.011
positive regulation of innate immune response GO:0045089 38 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
body morphogenesis GO:0010171 2 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
forebrain development GO:0030900 2 0.011
response to organic substance GO:0010033 284 0.011
organic substance transport GO:0071702 257 0.011
chromosome organization GO:0051276 360 0.011
salivary gland histolysis GO:0035070 88 0.011
defense response to virus GO:0051607 23 0.011
salivary gland development GO:0007431 162 0.011
humoral immune response GO:0006959 117 0.011
macromolecular complex assembly GO:0065003 256 0.010
g protein coupled receptor signaling pathway GO:0007186 136 0.010
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
amine metabolic process GO:0009308 12 0.010
Rat
cell motility GO:0048870 251 0.010
regulation of immune system process GO:0002682 176 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
negative regulation of gene expression GO:0010629 387 0.010
protein complex assembly GO:0006461 200 0.010
amide biosynthetic process GO:0043604 42 0.010
regulation of cellular response to stress GO:0080135 89 0.010
regulation of hydrolase activity GO:0051336 97 0.010
muscle structure development GO:0061061 224 0.010

SpdS disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.016
disease of anatomical entity DOID:7 0 0.012